GO_ID LEVEL(S) TERM NB_IN_REF FREQ_IN_REF NB_IN_SET FREQ_IN_SET P_VALUE ENRICHMENT/DEPLETION GENES_IN_SET GO:0019752 6 carboxylic acid metabolism 300 0.0465 14 0.2000 2.460062E-06 E ARG3,FUM1,YAT2,MSW1,ABZ1,LYS1,PCK1,ICL1,ACP1,CEM1,GCV3,GCV1,LEU2,BAT2 GO:0006082 5 organic acid metabolism 300 0.0465 14 0.2000 2.460062E-06 E ARG3,FUM1,YAT2,MSW1,ABZ1,LYS1,PCK1,ICL1,ACP1,CEM1,GCV3,GCV1,LEU2,BAT2 GO:0006656 10,9,11 phosphatidylcholine biosynthesis 7 0.0011 3 0.0429 4.102969E-05 E OPI3,CHO2,CPT1 GO:0009308 5 amine metabolism 218 0.0338 10 0.1429 8.666093E-05 E SHC1,ARG3,YAT2,MSW1,ABZ1,LYS1,GCV3,GCV1,LEU2,BAT2 GO:0046470 9,10 phosphatidylcholine metabolism 9 0.0014 3 0.0429 9.643502E-05 E OPI3,CHO2,CPT1 GO:0050875 3 cellular physiological process 4641 0.7191 63 0.9000 0.0001481 E SHC1,ARG3,CTM1,OPI3,STE3,MSS51,DPB11,BNA6,SED1,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SMF1,SUM1,DIC1,ECM38,COX10,FUM1,YAT2,MSW1,LSB3,SPP1,THI11,CHO2,MRM2,TSA2,ABZ1,CHK1,MIA40,APL3,LYS1,NUP42,PCK1,ICL1,PEX28,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,SGE1,MSU1,DAL5,PST1,CEM1,GCV3,AAC1,GCV1,RER1,COQ5,CDC13,YSC84,GTT1,CPT1,LEU2,BAT2,HXT9,AVT5 GO:0006807 4 nitrogen compound metabolism 236 0.0366 10 0.1429 0.0001636 E SHC1,ARG3,YAT2,MSW1,ABZ1,LYS1,GCV3,GCV1,LEU2,BAT2 GO:0009987 2 cellular process 4682 0.7254 63 0.9000 0.0002203 E SHC1,ARG3,CTM1,OPI3,STE3,MSS51,DPB11,BNA6,SED1,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SMF1,SUM1,DIC1,ECM38,COX10,FUM1,YAT2,MSW1,LSB3,SPP1,THI11,CHO2,MRM2,TSA2,ABZ1,CHK1,MIA40,APL3,LYS1,NUP42,PCK1,ICL1,PEX28,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,SGE1,MSU1,DAL5,PST1,CEM1,GCV3,AAC1,GCV1,RER1,COQ5,CDC13,YSC84,GTT1,CPT1,LEU2,BAT2,HXT9,AVT5 GO:0008610 6,5,7 lipid biosynthesis 124 0.0192 7 0.1000 0.0003068 E OPI3,LAS21,CHO2,LRO1,ACP1,CEM1,CPT1 GO:0046474 9,8,10 glycerophospholipid biosynthesis 34 0.0053 4 0.0571 0.0004321 E OPI3,LAS21,CHO2,CPT1 GO:0007582 2 physiological process 4771 0.7392 63 0.9000 0.0005068 E SHC1,ARG3,CTM1,OPI3,STE3,MSS51,DPB11,BNA6,SED1,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SMF1,SUM1,DIC1,ECM38,COX10,FUM1,YAT2,MSW1,LSB3,SPP1,THI11,CHO2,MRM2,TSA2,ABZ1,CHK1,MIA40,APL3,LYS1,NUP42,PCK1,ICL1,PEX28,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,SGE1,MSU1,DAL5,PST1,CEM1,GCV3,AAC1,GCV1,RER1,COQ5,CDC13,YSC84,GTT1,CPT1,LEU2,BAT2,HXT9,AVT5 GO:0006546 9,10 glycine catabolism 4 0.0006 2 0.0286 0.0006812 E GCV3,GCV1 GO:0051186 5 cofactor metabolism 148 0.0229 7 0.1000 0.0008563 E BNA6,ECM38,COX10,FUM1,ABZ1,COQ5,GTT1 GO:0006519 5 amino acid and derivative metabolism 197 0.0305 8 0.1143 0.0009689 E ARG3,YAT2,MSW1,LYS1,GCV3,GCV1,LEU2,BAT2 GO:0009071 8,9 serine family amino acid catabolism 5 0.0008 2 0.0286 0.0011234 E GCV3,GCV1 GO:0006650 8,9 glycerophospholipid metabolism 46 0.0071 4 0.0571 0.0013430 E OPI3,LAS21,CHO2,CPT1 GO:0006732 6 coenzyme metabolism 119 0.0184 6 0.0857 0.0014572 E BNA6,ECM38,FUM1,ABZ1,COQ5,GTT1 GO:0006544 8,9 glycine metabolism 6 0.0009 2 0.0286 0.0016674 E GCV3,GCV1 GO:0008654 8,7,9 phospholipid biosynthesis 52 0.0081 4 0.0571 0.0020939 E OPI3,LAS21,CHO2,CPT1 GO:0006520 6,7 amino acid metabolism 182 0.0282 7 0.1000 0.0026576 E ARG3,MSW1,LYS1,GCV3,GCV1,LEU2,BAT2 GO:0006749 7,6 glutathione metabolism 8 0.0012 2 0.0286 0.0030472 E ECM38,GTT1 GO:0009063 7,8 amino acid catabolism 28 0.0043 3 0.0429 0.0030828 E GCV3,GCV1,BAT2 GO:0009310 6,7 amine catabolism 31 0.0048 3 0.0429 0.0040990 E GCV3,GCV1,BAT2 GO:0044270 6,5 nitrogen compound catabolism 31 0.0048 3 0.0429 0.0040990 E GCV3,GCV1,BAT2 GO:0030503 6,5 regulation of cell redox homeostasis 10 0.0015 2 0.0286 0.0047944 E TSA2,TRX2 GO:0045454 5 cell redox homeostasis 10 0.0015 2 0.0286 0.0047944 E TSA2,TRX2 GO:0044255 5,6 cellular lipid metabolism 208 0.0322 7 0.1000 0.0052797 E OPI3,LAS21,CHO2,LRO1,ACP1,CEM1,CPT1 GO:0046467 7,6,8 membrane lipid biosynthesis 71 0.0110 4 0.0571 0.0061701 E OPI3,LAS21,CHO2,CPT1 GO:0009058 4 biosynthesis 1184 0.1835 21 0.3000 0.0062437 E SHC1,ARG3,OPI3,MSS51,BNA6,LAS21,MEF1,COX10,MSW1,THI11,CHO2,LYS1,PCK1,PMT6,MRPL19,LRO1,ACP1,CEM1,CPT1,LEU2,BAT2 GO:0006633 8,7,6 fatty acid biosynthesis 12 0.0019 2 0.0286 0.0068842 E ACP1,CEM1 GO:0006730 5 one-carbon compound metabolism 12 0.0019 2 0.0286 0.0068842 E GCV3,GCV1 GO:0006629 5 lipid metabolism 222 0.0344 7 0.1000 0.0072737 E OPI3,LAS21,CHO2,LRO1,ACP1,CEM1,CPT1 GO:0009082 8,9 branched chain family amino acid biosynthesis 13 0.0020 2 0.0286 0.0080500 E LEU2,BAT2 GO:0006644 7,8 phospholipid metabolism 79 0.0122 4 0.0571 0.0087796 E OPI3,LAS21,CHO2,CPT1 GO:0006751 8,7 glutathione catabolism 1 0.0002 1 0.0143 0.0108460 E ECM38 GO:0044273 6 sulfur compound catabolism 1 0.0002 1 0.0143 0.0108460 E ECM38 GO:0046482 6,7,9,8 para-aminobenzoic acid metabolism 1 0.0002 1 0.0143 0.0108460 E ABZ1 GO:0045946 10,9,8 positive regulation of translation 1 0.0002 1 0.0143 0.0108460 E MSS51 GO:0006106 9,7 fumarate metabolism 1 0.0002 1 0.0143 0.0108460 E FUM1 GO:0015719 8,9 allantoate transport 1 0.0002 1 0.0143 0.0108460 E DAL5 GO:0009081 7,8 branched chain family amino acid metabolism 16 0.0025 2 0.0286 0.0119964 E LEU2,BAT2 GO:0044237 4 cellular metabolism 3376 0.5231 45 0.6429 0.0125742 E SHC1,ARG3,CTM1,OPI3,MSS51,DPB11,BNA6,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SUM1,ECM38,COX10,FUM1,YAT2,MSW1,SPP1,THI11,CHO2,MRM2,ABZ1,CHK1,LYS1,PCK1,ICL1,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,MSU1,CEM1,GCV3,AAC1,GCV1,COQ5,GTT1,CPT1,LEU2,BAT2 GO:0009109 7 coenzyme catabolism 17 0.0026 2 0.0286 0.0134523 E ECM38,FUM1 GO:0016053 6 organic acid biosynthesis 17 0.0026 2 0.0286 0.0134523 E ACP1,CEM1 GO:0031570 7 DNA integrity checkpoint 17 0.0026 2 0.0286 0.0134523 E DPB11,CHK1 GO:0046394 7 carboxylic acid biosynthesis 17 0.0026 2 0.0286 0.0134523 E ACP1,CEM1 GO:0051187 6 cofactor catabolism 18 0.0028 2 0.0286 0.0149740 E ECM38,FUM1 GO:0008152 3 metabolism 3427 0.5310 45 0.6429 0.0163040 E SHC1,ARG3,CTM1,OPI3,MSS51,DPB11,BNA6,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SUM1,ECM38,COX10,FUM1,YAT2,MSW1,SPP1,THI11,CHO2,MRM2,ABZ1,CHK1,LYS1,PCK1,ICL1,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,MSU1,CEM1,GCV3,AAC1,GCV1,COQ5,GTT1,CPT1,LEU2,BAT2 GO:0008652 7,8 amino acid biosynthesis 99 0.0153 4 0.0571 0.0178576 E ARG3,LYS1,LEU2,BAT2 GO:0006890 9,7,6,8 retrograde transport, Golgi to ER 21 0.0033 2 0.0286 0.0199079 E TRX2,RER1 GO:0006790 5 sulfur metabolism 57 0.0088 3 0.0429 0.0203041 E ECM38,TRX2,GTT1 GO:0044249 5 cellular biosynthesis 1105 0.1712 18 0.2571 0.0210241 E SHC1,ARG3,MSS51,BNA6,LAS21,MEF1,COX10,MSW1,THI11,LYS1,PCK1,PMT6,MRPL19,LRO1,ACP1,CEM1,LEU2,BAT2 GO:0046463 7,8,9 acylglycerol biosynthesis 2 0.0003 1 0.0143 0.0214600 E LRO1 GO:0046504 6 glycerol ether biosynthesis 2 0.0003 1 0.0143 0.0214600 E LRO1 GO:0046460 7,6,8 neutral lipid biosynthesis 2 0.0003 1 0.0143 0.0214600 E LRO1 GO:0019432 8,9,10 triacylglycerol biosynthesis 2 0.0003 1 0.0143 0.0214600 E LRO1 GO:0045017 7,6,8 glycerolipid biosynthesis 2 0.0003 1 0.0143 0.0214600 E LRO1 GO:0006436 10,11,9 tryptophanyl-tRNA aminoacylation 2 0.0003 1 0.0143 0.0214600 E MSW1 GO:0019915 6 sequestering of lipid 2 0.0003 1 0.0143 0.0214600 E LRO1 GO:0009069 7,8 serine family amino acid metabolism 22 0.0034 2 0.0286 0.0216672 E GCV3,GCV1 GO:0006643 6,7 membrane lipid metabolism 106 0.0164 4 0.0571 0.0219044 E OPI3,LAS21,CHO2,CPT1 GO:0044271 6,5 nitrogen compound biosynthesis 108 0.0167 4 0.0571 0.0231414 E ARG3,LYS1,LEU2,BAT2 GO:0009309 6,7 amine biosynthesis 108 0.0167 4 0.0571 0.0231414 E ARG3,LYS1,LEU2,BAT2 GO:0016233 9 telomere capping 3 0.0005 1 0.0143 0.0318458 E CDC13 GO:0006285 9,8 base-excision repair, AP site formation 3 0.0005 1 0.0143 0.0318458 E NTG1 GO:0009437 7,8 carnitine metabolism 3 0.0005 1 0.0143 0.0318458 E YAT2 GO:0006835 7,8 dicarboxylic acid transport 3 0.0005 1 0.0143 0.0318458 E DIC1 GO:0006092 7 main pathways of carbohydrate metabolism 70 0.0108 3 0.0429 0.0331218 E FUM1,PCK1,ICL1 GO:0006766 5 vitamin metabolism 74 0.0115 3 0.0429 0.0376021 E BNA6,YAT2,THI11 GO:0006767 6 water-soluble vitamin metabolism 74 0.0115 3 0.0429 0.0376021 E BNA6,YAT2,THI11 GO:0015980 6 energy derivation by oxidation of organic compounds 194 0.0301 5 0.0714 0.0404518 E FUM1,PCK1,ICL1,AAC1,COQ5 GO:0006662 5 glycerol ether metabolism 4 0.0006 1 0.0143 0.0420069 E LRO1 GO:0046160 8,7 heme a metabolism 4 0.0006 1 0.0143 0.0420069 E COX10 GO:0006784 9,8 heme a biosynthesis 4 0.0006 1 0.0143 0.0420069 E COX10 GO:0006638 6,7 neutral lipid metabolism 4 0.0006 1 0.0143 0.0420069 E LRO1 GO:0006097 7,8 glyoxylate cycle 4 0.0006 1 0.0143 0.0420069 E ICL1 GO:0046486 6,7 glycerolipid metabolism 4 0.0006 1 0.0143 0.0420069 E LRO1 GO:0046487 6,7 glyoxylate metabolism 4 0.0006 1 0.0143 0.0420069 E ICL1 GO:0006639 7,6,8 acylglycerol metabolism 4 0.0006 1 0.0143 0.0420069 E LRO1 GO:0006641 8,7,9 triacylglycerol metabolism 4 0.0006 1 0.0143 0.0420069 E LRO1 GO:0044248 5 cellular catabolism 347 0.0538 7 0.1000 0.0475837 E ECM38,FUM1,HRD3,MSU1,GCV3,GCV1,BAT2 GO:0044238 4 primary metabolism 3152 0.4884 39 0.5571 0.0491985 E SHC1,ARG3,CTM1,OPI3,MSS51,DPB11,BNA6,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SUM1,COX10,FUM1,YAT2,MSW1,SPP1,CHO2,MRM2,CHK1,LYS1,PCK1,ICL1,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,MSU1,CEM1,GCV3,GCV1,CPT1,LEU2,BAT2 GO:0009060 8 aerobic respiration 84 0.0130 3 0.0429 0.0497296 E FUM1,AAC1,COQ5 GO:0009098 9,10 leucine biosynthesis 5 0.0008 1 0.0143 0.0519469 E LEU2 GO:0000076 8 DNA replication checkpoint 5 0.0008 1 0.0143 0.0519469 E DPB11 GO:0042364 7 water-soluble vitamin biosynthesis 38 0.0059 2 0.0286 0.0556167 E BNA6,THI11 GO:0009110 6 vitamin biosynthesis 38 0.0059 2 0.0286 0.0556167 E BNA6,THI11 GO:0045333 7 cellular respiration 89 0.0138 3 0.0429 0.0562171 E FUM1,AAC1,COQ5 GO:0009056 4 catabolism 369 0.0572 7 0.1000 0.0584353 E ECM38,FUM1,HRD3,MSU1,GCV3,GCV1,BAT2 GO:0006091 5 generation of precursor metabolites and energy 224 0.0347 5 0.0714 0.0610806 E FUM1,PCK1,ICL1,AAC1,COQ5 GO:0045041 11,9,7,10,8 protein import into mitochondrial intermembrane space 6 0.0009 1 0.0143 0.0616693 E MIA40 GO:0006591 8,9,6,5 ornithine metabolism 6 0.0009 1 0.0143 0.0616693 E ARG3 GO:0006631 6,7 fatty acid metabolism 43 0.0067 2 0.0286 0.0677319 E ACP1,CEM1 GO:0006551 8,9 leucine metabolism 7 0.0011 1 0.0143 0.0711776 E LEU2 GO:0006621 6 protein retention in ER 7 0.0011 1 0.0143 0.0711776 E RER1 GO:0009435 9,8,11,10 NAD biosynthesis 7 0.0011 1 0.0143 0.0711776 E BNA6 GO:0006828 9,10 manganese ion transport 7 0.0011 1 0.0143 0.0711776 E SMF1 GO:0006348 13,8,11,6 chromatin silencing at telomere 45 0.0070 2 0.0286 0.0726905 E SUM1,SPP1 GO:0031509 12 telomeric heterochromatin formation 45 0.0070 2 0.0286 0.0726905 E SUM1,SPP1 GO:0006733 7 oxidoreduction coenzyme metabolism 45 0.0070 2 0.0286 0.0726905 E BNA6,COQ5 GO:0006810 4,5 transport 924 0.1432 13 0.1857 0.0754950 E SMF1,DIC1,MIA40,APL3,NUP42,TRX2,SGE1,DAL5,AAC1,RER1,YSC84,HXT9,AVT5 GO:0000075 6 cell cycle checkpoint 47 0.0073 2 0.0286 0.0776967 E DPB11,CHK1 GO:0019363 8,7,9 pyridine nucleotide biosynthesis 8 0.0012 1 0.0143 0.0804752 E BNA6 GO:0019878 10,11 lysine biosynthesis via aminoadipic acid 8 0.0012 1 0.0143 0.0804752 E LYS1 GO:0015718 7,8 monocarboxylic acid transport 8 0.0012 1 0.0143 0.0804752 E DAL5 GO:0051234 4 establishment of localization 942 0.1460 13 0.1857 0.0806179 E SMF1,DIC1,MIA40,APL3,NUP42,TRX2,SGE1,DAL5,AAC1,RER1,YSC84,HXT9,AVT5 GO:0006974 5 response to DNA damage stimulus 177 0.0274 4 0.0571 0.0826365 E DPB11,NTG1,RRD1,CHK1 GO:0046942 6,7 carboxylic acid transport 50 0.0077 2 0.0286 0.0852725 E DIC1,DAL5 GO:0015849 5,6 organic acid transport 51 0.0079 2 0.0286 0.0878106 E DIC1,DAL5 GO:0009719 4 response to endogenous stimulus 183 0.0284 4 0.0571 0.0887192 E DPB11,NTG1,RRD1,CHK1 GO:0006553 8,9 lysine metabolism 9 0.0014 1 0.0143 0.0895655 E LYS1 GO:0006760 6,8,7 folic acid and derivative metabolism 9 0.0014 1 0.0143 0.0895655 E ABZ1 GO:0019794 7,8 nonprotein amino acid metabolism 9 0.0014 1 0.0143 0.0895655 E ARG3 GO:0009085 9,10 lysine biosynthesis 9 0.0014 1 0.0143 0.0895655 E LYS1 GO:0006031 10,9,11,8,7 chitin biosynthesis 9 0.0014 1 0.0143 0.0895655 E SHC1 GO:0006743 8 ubiquinone metabolism 9 0.0014 1 0.0143 0.0895655 E COQ5 GO:0051179 3 localization 991 0.1535 13 0.1857 0.0938293 E SMF1,DIC1,MIA40,APL3,NUP42,TRX2,SGE1,DAL5,AAC1,RER1,YSC84,HXT9,AVT5 GO:0006284 8,7 base-excision repair 10 0.0015 1 0.0143 0.0984518 E NTG1 GO:0006791 6 sulfur utilization 10 0.0015 1 0.0143 0.0984518 E TRX2 GO:0006526 9,10,7,6 arginine biosynthesis 10 0.0015 1 0.0143 0.0984518 E ARG3 GO:0000103 7 sulfate assimilation 10 0.0015 1 0.0143 0.0984518 E TRX2 GO:0044262 6 cellular carbohydrate metabolism 201 0.0311 4 0.0571 0.1070201 E SHC1,FUM1,PCK1,ICL1 GO:0006839 8,6,7 mitochondrial transport 11 0.0017 1 0.0143 0.1071374 E AAC1 GO:0006030 9,7,8,10 chitin metabolism 11 0.0017 1 0.0143 0.1071374 E SHC1 GO:0046349 7,8 amino sugar biosynthesis 12 0.0019 1 0.0143 0.1156255 E SHC1 GO:0006045 9,10 N-acetylglucosamine biosynthesis 12 0.0019 1 0.0143 0.1156255 E SHC1 GO:0006042 8,9 glucosamine biosynthesis 12 0.0019 1 0.0143 0.1156255 E SHC1 GO:0016051 7,6 carbohydrate biosynthesis 63 0.0098 2 0.0286 0.1183173 E SHC1,PCK1 GO:0007015 9 actin filament organization 63 0.0098 2 0.0286 0.1183173 E LSB3,YSC84 GO:0015893 5,6,7 drug transport 13 0.0020 1 0.0143 0.1239193 E SGE1 GO:0000077 8,7 DNA damage checkpoint 13 0.0020 1 0.0143 0.1239193 E CHK1 GO:0005975 5 carbohydrate metabolism 219 0.0339 4 0.0571 0.1248740 E SHC1,FUM1,PCK1,ICL1 GO:0000074 5 regulation of progression through cell cycle 140 0.0217 3 0.0429 0.1288796 E DPB11,SUM1,CHK1 GO:0006044 8,9 N-acetylglucosamine metabolism 14 0.0022 1 0.0143 0.1320219 E SHC1 GO:0046148 6 pigment biosynthesis 14 0.0022 1 0.0143 0.1320219 E COX10 GO:0006041 7,8 glucosamine metabolism 14 0.0022 1 0.0143 0.1320219 E SHC1 GO:0006040 6,7 amino sugar metabolism 14 0.0022 1 0.0143 0.1320219 E SHC1 GO:0000394 9 RNA splicing, via endonucleolytic cleavage and ligation 14 0.0022 1 0.0143 0.1320219 E POA1 GO:0006779 7 porphyrin biosynthesis 14 0.0022 1 0.0143 0.1320219 E COX10 GO:0006783 8,7 heme biosynthesis 14 0.0022 1 0.0143 0.1320219 E COX10 GO:0019674 10,9 NAD metabolism 14 0.0022 1 0.0143 0.1320219 E BNA6 GO:0006388 10,9 tRNA splicing 14 0.0022 1 0.0143 0.1320219 E POA1 GO:0006272 10 leading strand elongation 14 0.0022 1 0.0143 0.1320219 E DPB11 GO:0042770 6 DNA damage response, signal transduction 14 0.0022 1 0.0143 0.1320219 E CHK1 GO:0007067 7 mitosis 146 0.0226 3 0.0429 0.1372259 E RRD1,SUM1,CSE2 GO:0046483 5 heterocycle metabolism 71 0.0110 2 0.0286 0.1381932 E COX10,ABZ1 GO:0051188 6 cofactor biosynthesis 71 0.0110 2 0.0286 0.1381932 E BNA6,COX10 GO:0000051 5,4 urea cycle intermediate metabolism 15 0.0023 1 0.0143 0.1399365 E ARG3 GO:0042440 5 pigment metabolism 15 0.0023 1 0.0143 0.1399365 E COX10 GO:0000011 7 vacuole inheritance 15 0.0023 1 0.0143 0.1399365 E TRX2 GO:0006778 6 porphyrin metabolism 15 0.0023 1 0.0143 0.1399365 E COX10 GO:0006525 8,9,6,5 arginine metabolism 15 0.0023 1 0.0143 0.1399365 E ARG3 GO:0042168 7,6 heme metabolism 15 0.0023 1 0.0143 0.1399365 E COX10 GO:0046356 8 acetyl-CoA catabolism 15 0.0023 1 0.0143 0.1399365 E FUM1 GO:0006099 9,8 tricarboxylic acid cycle 15 0.0023 1 0.0143 0.1399365 E FUM1 GO:0000087 6 M phase of mitotic cell cycle 148 0.0229 3 0.0429 0.1399616 E RRD1,SUM1,CSE2 GO:0006281 7,6 DNA repair 150 0.0232 3 0.0429 0.1426716 E DPB11,NTG1,RRD1 GO:0050896 3 response to stimulus 549 0.0851 7 0.1000 0.1434958 E STE3,DPB11,NTG1,RRD1,CHK1,TRX2,SGE1 GO:0006493 10,9 protein amino acid O-linked glycosylation 16 0.0025 1 0.0143 0.1476661 E PMT6 GO:0051244 4 regulation of cellular physiological process 566 0.0877 7 0.1000 0.1481668 E MSS51,DPB11,SUM1,SPP1,TSA2,CHK1,TRX2 GO:0050794 3 regulation of cellular process 568 0.0880 7 0.1000 0.1486575 E MSS51,DPB11,SUM1,SPP1,TSA2,CHK1,TRX2 GO:0006888 9,7,6,8 ER to Golgi transport 76 0.0118 2 0.0286 0.1502244 E TRX2,RER1 GO:0050791 3 regulation of physiological process 584 0.0905 7 0.1000 0.1521283 E MSS51,DPB11,SUM1,SPP1,TSA2,CHK1,TRX2 GO:0050789 2 regulation of biological process 597 0.0925 7 0.1000 0.1543472 E MSS51,DPB11,SUM1,SPP1,TSA2,CHK1,TRX2 GO:0016571 12,9,10 histone methylation 17 0.0026 1 0.0143 0.1552137 E SPP1 GO:0016458 6 gene silencing 79 0.0122 2 0.0286 0.1572605 E SUM1,SPP1 GO:0045814 4 negative regulation of gene expression, epigenetic 79 0.0122 2 0.0286 0.1572605 E SUM1,SPP1 GO:0031507 11 heterochromatin formation 79 0.0122 2 0.0286 0.1572605 E SUM1,SPP1 GO:0006342 12,7,10,5 chromatin silencing 79 0.0122 2 0.0286 0.1572605 E SUM1,SPP1 GO:0006261 8 DNA-dependent DNA replication 80 0.0124 2 0.0286 0.1595723 E DPB11,TRX2 GO:0009067 8,9 aspartate family amino acid biosynthesis 18 0.0028 1 0.0143 0.1625822 E LYS1 GO:0019748 4 secondary metabolism 18 0.0028 1 0.0143 0.1625822 E COX10 GO:0031497 10 chromatin assembly 84 0.0130 2 0.0286 0.1686402 E SUM1,SPP1 GO:0040029 3 regulation of gene expression, epigenetic 84 0.0130 2 0.0286 0.1686402 E SUM1,SPP1 GO:0006100 8 tricarboxylic acid cycle intermediate metabolism 19 0.0029 1 0.0143 0.1697747 E FUM1 GO:0006081 5 aldehyde metabolism 19 0.0029 1 0.0143 0.1697747 E ICL1 GO:0009228 8,9 thiamin biosynthesis 19 0.0029 1 0.0143 0.1697747 E THI11 GO:0006950 4 response to stress 395 0.0612 5 0.0714 0.1723254 E DPB11,NTG1,RRD1,CHK1,TRX2 GO:0007049 4 cell cycle 397 0.0615 5 0.0714 0.1729828 E DPB11,RRD1,SUM1,CHK1,CSE2 GO:0016192 5,6 vesicle-mediated transport 282 0.0437 4 0.0571 0.1760937 E APL3,TRX2,RER1,YSC84 GO:0006273 10 lagging strand elongation 20 0.0031 1 0.0143 0.1767940 E DPB11 GO:0006772 8 thiamin metabolism 20 0.0031 1 0.0143 0.1767940 E THI11 GO:0006084 7 acetyl-CoA metabolism 20 0.0031 1 0.0143 0.1767940 E FUM1 GO:0045005 9 maintenance of fidelity during DNA-dependent DNA replication 20 0.0031 1 0.0143 0.1767940 E DPB11 GO:0008213 8 protein amino acid alkylation 20 0.0031 1 0.0143 0.1767940 E SPP1 GO:0042724 8 thiamin and derivative biosynthesis 20 0.0031 1 0.0143 0.1767940 E THI11 GO:0006479 9,8 protein amino acid methylation 20 0.0031 1 0.0143 0.1767940 E SPP1 GO:0030433 10,12,11,13 ER-associated protein catabolism 20 0.0031 1 0.0143 0.1767940 E HRD3 GO:0006298 8,10,7 mismatch repair 20 0.0031 1 0.0143 0.1767940 E DPB11 GO:0006464 7 protein modification 431 0.0668 5 0.0714 0.1809472 E CTM1,LAS21,SPP1,CHK1,PMT6 GO:0015749 6,7 monosaccharide transport 21 0.0033 1 0.0143 0.1836429 E HXT9 GO:0008645 7,8 hexose transport 21 0.0033 1 0.0143 0.1836429 E HXT9 GO:0017038 6,7 protein import 91 0.0141 2 0.0286 0.1837574 E MIA40,NUP42 GO:0009628 4 response to abiotic stimulus 301 0.0466 4 0.0571 0.1865339 E STE3,RRD1,TRX2,SGE1 GO:0042723 7 thiamin and derivative metabolism 22 0.0034 1 0.0143 0.1903243 E THI11 GO:0006515 9,10 misfolded or incompletely synthesized protein catabolism 22 0.0034 1 0.0143 0.1903243 E HRD3 GO:0042144 7,4 vacuole fusion, non-autophagic 22 0.0034 1 0.0143 0.1903243 E TRX2 GO:0000750 7,8,6 signal transduction during conjugation with cellular fusion 22 0.0034 1 0.0143 0.1903243 E STE3 GO:0030466 13,8,11,6 chromatin silencing at silent mating-type cassette 22 0.0034 1 0.0143 0.1903243 E SUM1 GO:0006408 11,9,10,8 snRNA export from nucleus 23 0.0036 1 0.0143 0.1968408 E NUP42 GO:0006506 10,11,9,12 GPI anchor biosynthesis 23 0.0036 1 0.0143 0.1968408 E LAS21 GO:0006610 11,9,8,10 ribosomal protein import into nucleus 23 0.0036 1 0.0143 0.1968408 E NUP42 GO:0006607 11,9,8,10 NLS-bearing substrate import into nucleus 23 0.0036 1 0.0143 0.1968408 E NUP42 GO:0006608 11,9,8,10 snRNP protein import into nucleus 23 0.0036 1 0.0143 0.1968408 E NUP42 GO:0051030 8,7,9 snRNA transport 23 0.0036 1 0.0143 0.1968408 E NUP42 GO:0006333 9 chromatin assembly or disassembly 100 0.0155 2 0.0286 0.2016387 E SUM1,SPP1 GO:0030036 8 actin cytoskeleton organization and biogenesis 100 0.0155 2 0.0286 0.2016387 E LSB3,YSC84 GO:0030472 9,11,5 mitotic spindle organization and biogenesis in nucleus 24 0.0037 1 0.0143 0.2031953 E RRD1 GO:0006505 10,11 GPI anchor metabolism 24 0.0037 1 0.0143 0.2031953 E LAS21 GO:0046489 10,9,11 phosphoinositide biosynthesis 24 0.0037 1 0.0143 0.2031953 E LAS21 GO:0009084 8,9 glutamine family amino acid biosynthesis 24 0.0037 1 0.0143 0.2031953 E ARG3 GO:0006399 7 tRNA metabolism 103 0.0160 2 0.0286 0.2071836 E POA1,MSW1 GO:0006260 7 DNA replication 103 0.0160 2 0.0286 0.2071836 E DPB11,TRX2 GO:0030029 7 actin filament-based process 104 0.0161 2 0.0286 0.2089842 E LSB3,YSC84 GO:0006270 9 DNA replication initiation 25 0.0039 1 0.0143 0.2093905 E DPB11 GO:0006609 11,9,8,10 mRNA-binding (hnRNP) protein import into nucleus 25 0.0039 1 0.0143 0.2093905 E NUP42 GO:0006576 6,7 biogenic amine metabolism 25 0.0039 1 0.0143 0.2093905 E YAT2 GO:0042221 5 response to chemical stimulus 220 0.0341 3 0.0429 0.2135448 E STE3,TRX2,SGE1 GO:0006407 11,9,10,8 rRNA export from nucleus 26 0.0040 1 0.0143 0.2154289 E NUP42 GO:0006409 11,9,10,8 tRNA export from nucleus 26 0.0040 1 0.0143 0.2154289 E NUP42 GO:0051029 8,7,9 rRNA transport 26 0.0040 1 0.0143 0.2154289 E NUP42 GO:0051031 8,7,9 tRNA transport 26 0.0040 1 0.0143 0.2154289 E NUP42 GO:0006094 9,10,8 gluconeogenesis 26 0.0040 1 0.0143 0.2154289 E PCK1 GO:0019725 4 cell homeostasis 108 0.0167 2 0.0286 0.2159449 E TSA2,TRX2 GO:0000278 5 mitotic cell cycle 231 0.0358 3 0.0429 0.2196231 E RRD1,SUM1,CSE2 GO:0000002 7 mitochondrial genome maintenance 27 0.0042 1 0.0143 0.2213132 E SED1 GO:0007186 6 G-protein coupled receptor protein signaling pathway 27 0.0042 1 0.0143 0.2213132 E STE3 GO:0006999 7 nuclear pore organization and biogenesis 27 0.0042 1 0.0143 0.2213132 E NUP42 GO:0006575 6 amino acid derivative metabolism 27 0.0042 1 0.0143 0.2213132 E YAT2 GO:0007001 7 chromosome organization and biogenesis (sensu Eukaryota) 243 0.0377 3 0.0429 0.2246347 E SUM1,SPP1,CDC13 GO:0042592 3 homeostasis 114 0.0177 2 0.0286 0.2256498 E TSA2,TRX2 GO:0046364 7,8 monosaccharide biosynthesis 28 0.0043 1 0.0143 0.2270460 E PCK1 GO:0043284 7,5,6 biopolymer biosynthesis 28 0.0043 1 0.0143 0.2270460 E SHC1 GO:0019319 8,9 hexose biosynthesis 28 0.0043 1 0.0143 0.2270460 E PCK1 GO:0000271 8,7,6 polysaccharide biosynthesis 28 0.0043 1 0.0143 0.2270460 E SHC1 GO:0051276 6 chromosome organization and biogenesis 255 0.0395 3 0.0429 0.2280123 E SUM1,SPP1,CDC13 GO:0000279 5 M phase 257 0.0398 3 0.0429 0.2284217 E RRD1,SUM1,CSE2 GO:0006445 9,8,7 regulation of translation 29 0.0045 1 0.0143 0.2326298 E MSS51 GO:0045185 5 maintenance of protein localization 29 0.0045 1 0.0143 0.2326298 E RER1 GO:0043038 7,8 amino acid activation 30 0.0046 1 0.0143 0.2380671 E MSW1 GO:0006418 9,10,8 tRNA aminoacylation for protein translation 30 0.0046 1 0.0143 0.2380671 E MSW1 GO:0046165 6 alcohol biosynthesis 30 0.0046 1 0.0143 0.2380671 E PCK1 GO:0043039 8,9 tRNA aminoacylation 30 0.0046 1 0.0143 0.2380671 E MSW1 GO:0006417 8,7,6 regulation of protein biosynthesis 30 0.0046 1 0.0143 0.2380671 E MSS51 GO:0006271 9 DNA strand elongation 30 0.0046 1 0.0143 0.2380671 E DPB11 GO:0045892 9 negative regulation of transcription, DNA-dependent 124 0.0192 2 0.0286 0.2398352 E SUM1,SPP1 GO:0042493 6 response to drug 31 0.0048 1 0.0143 0.2433603 E SGE1 GO:0006769 9,8 nicotinamide metabolism 31 0.0048 1 0.0143 0.2433603 E BNA6 GO:0006289 8,7 nucleotide-excision repair 31 0.0048 1 0.0143 0.2433603 E DPB11 GO:0051235 4 maintenance of localization 31 0.0048 1 0.0143 0.2433603 E RER1 GO:0030384 9,10 phosphoinositide metabolism 31 0.0048 1 0.0143 0.2433603 E LAS21 GO:0016481 8 negative regulation of transcription 128 0.0198 2 0.0286 0.2448120 E SUM1,SPP1 GO:0006338 10 chromatin remodeling 132 0.0205 2 0.0286 0.2493936 E SUM1,SPP1 GO:0045934 7 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 138 0.0214 2 0.0286 0.2555341 E SUM1,SPP1 GO:0007047 6 cell wall organization and biogenesis 141 0.0218 2 0.0286 0.2582800 E SED1,PST1 GO:0045229 5 external encapsulating structure organization and biogenesis 141 0.0218 2 0.0286 0.2582800 E SED1,PST1 GO:0048193 8,6,7 Golgi vesicle transport 141 0.0218 2 0.0286 0.2582800 E TRX2,RER1 GO:0008033 8 tRNA processing 34 0.0053 1 0.0143 0.2584001 E POA1 GO:0008643 5,6 carbohydrate transport 34 0.0053 1 0.0143 0.2584001 E HXT9 GO:0019362 8,7 pyridine nucleotide metabolism 34 0.0053 1 0.0143 0.2584001 E BNA6 GO:0043414 7 biopolymer methylation 35 0.0054 1 0.0143 0.2631412 E SPP1 GO:0031324 6 negative regulation of cellular metabolism 150 0.0232 2 0.0286 0.2652553 E SUM1,SPP1 GO:0042158 8,7 lipoprotein biosynthesis 36 0.0056 1 0.0143 0.2677501 E LAS21 GO:0042157 7 lipoprotein metabolism 36 0.0056 1 0.0143 0.2677501 E LAS21 GO:0006497 9,8 protein lipidation 36 0.0056 1 0.0143 0.2677501 E LAS21 GO:0009892 5 negative regulation of metabolism 157 0.0243 2 0.0286 0.2694166 E SUM1,SPP1 GO:0006508 7 proteolysis 157 0.0243 2 0.0286 0.2694166 E PRD1,HRD3 GO:0006066 5 alcohol metabolism 157 0.0243 2 0.0286 0.2694166 E YAT2,PCK1 GO:0030471 4 spindle pole body and microtubule cycle (sensu Fungi) 37 0.0057 1 0.0143 0.2722291 E RRD1 GO:0006090 7 pyruvate metabolism 37 0.0057 1 0.0143 0.2722291 E PCK1 GO:0007031 6 peroxisome organization and biogenesis 37 0.0057 1 0.0143 0.2722291 E PEX28 GO:0051243 5 negative regulation of cellular physiological process 170 0.0263 2 0.0286 0.2743956 E SUM1,SPP1 GO:0048523 4 negative regulation of cellular process 170 0.0263 2 0.0286 0.2743956 E SUM1,SPP1 GO:0043118 4 negative regulation of physiological process 172 0.0267 2 0.0286 0.2748622 E SUM1,SPP1 GO:0048519 3 negative regulation of biological process 178 0.0276 2 0.0286 0.2758114 E SUM1,SPP1 GO:0016568 9 chromatin modification 181 0.0280 2 0.0286 0.2760413 E SUM1,SPP1 GO:0048308 6 organelle inheritance 38 0.0059 1 0.0143 0.2765803 E TRX2 GO:0007033 6 vacuole organization and biogenesis 39 0.0060 1 0.0143 0.2808060 E TRX2 GO:0007166 5 cell surface receptor linked signal transduction 40 0.0062 1 0.0143 0.2849084 E STE3 GO:0007052 8,10 mitotic spindle organization and biogenesis 42 0.0065 1 0.0143 0.2927515 E RRD1 GO:0009064 7,8 glutamine family amino acid metabolism 43 0.0067 1 0.0143 0.2964964 E ARG3 GO:0007051 9 spindle organization and biogenesis 43 0.0067 1 0.0143 0.2964964 E RRD1 GO:0000041 8,9 transition metal ion transport 43 0.0067 1 0.0143 0.2964964 E SMF1 GO:0006752 7 group transfer coenzyme metabolism 44 0.0068 1 0.0143 0.3001264 E ABZ1 GO:0006611 10,8,9 protein export from nucleus 45 0.0070 1 0.0143 0.3036433 E NUP42 GO:0009066 7,8 aspartate family amino acid metabolism 45 0.0070 1 0.0143 0.3036433 E LYS1 GO:0000723 8 telomere maintenance 45 0.0070 1 0.0143 0.3036433 E CDC13 GO:0009889 5 regulation of biosynthesis 46 0.0071 1 0.0143 0.3070492 E MSS51 GO:0006606 10,8,7,9 protein import into nucleus 46 0.0071 1 0.0143 0.3070492 E NUP42 GO:0031326 6 regulation of cellular biosynthesis 46 0.0071 1 0.0143 0.3070492 E MSS51 GO:0051246 6,5 regulation of protein metabolism 46 0.0071 1 0.0143 0.3070492 E MSS51 GO:0051170 9,7,8 nuclear import 46 0.0071 1 0.0143 0.3070492 E NUP42 GO:0043161 11,12 proteasomal ubiquitin-dependent protein catabolism 46 0.0071 1 0.0143 0.3070492 E HRD3 GO:0006626 10,8,9 protein targeting to mitochondrion 47 0.0073 1 0.0143 0.3103461 E MIA40 GO:0007088 8,6 regulation of mitosis 48 0.0074 1 0.0143 0.3135358 E SUM1 GO:0006997 6 nuclear organization and biogenesis 49 0.0076 1 0.0143 0.3166203 E NUP42 GO:0015674 7,8 di-, tri-valent inorganic cation transport 51 0.0079 1 0.0143 0.3224811 E SMF1 GO:0006979 6,5 response to oxidative stress 52 0.0081 1 0.0143 0.3252610 E TRX2 GO:0005976 6 polysaccharide metabolism 53 0.0082 1 0.0143 0.3279430 E SHC1 GO:0044264 6,7 cellular polysaccharide metabolism 53 0.0082 1 0.0143 0.3279430 E SHC1 GO:0000749 7,5 response to pheromone during conjugation with cellular fusion 53 0.0082 1 0.0143 0.3279430 E STE3 GO:0006800 5 oxygen and reactive oxygen species metabolism 54 0.0084 1 0.0143 0.3305288 E TRX2 GO:0009165 6,7 nucleotide biosynthesis 55 0.0085 1 0.0143 0.3330202 E BNA6 GO:0000070 8,6 mitotic sister chromatid segregation 55 0.0085 1 0.0143 0.3330202 E CSE2 GO:0000819 5 sister chromatid segregation 55 0.0085 1 0.0143 0.3330202 E CSE2 GO:0009108 7 coenzyme biosynthesis 57 0.0088 1 0.0143 0.3377265 E BNA6 GO:0030001 7,8 metal ion transport 57 0.0088 1 0.0143 0.3377265 E SMF1 GO:0006725 5 aromatic compound metabolism 57 0.0088 1 0.0143 0.3377265 E ABZ1 GO:0006944 3 membrane fusion 58 0.0090 1 0.0143 0.3399448 E TRX2 GO:0016569 10 covalent chromatin modification 59 0.0091 1 0.0143 0.3420754 E SPP1 GO:0016570 11,8 histone modification 59 0.0091 1 0.0143 0.3420754 E SPP1 GO:0006970 5 response to osmotic stress 59 0.0091 1 0.0143 0.3420754 E RRD1 GO:0006406 11,9,10,8 mRNA export from nucleus 62 0.0096 1 0.0143 0.3479567 E NUP42 GO:0051028 8,7,9 mRNA transport 62 0.0096 1 0.0143 0.3479567 E NUP42 GO:0006401 7 RNA catabolism 64 0.0099 1 0.0143 0.3514678 E MSU1 GO:0006006 8,9 glucose metabolism 65 0.0101 1 0.0143 0.3531050 E PCK1 GO:0006486 9,8 protein amino acid glycosylation 67 0.0104 1 0.0143 0.3561500 E PMT6 GO:0043413 7 biopolymer glycosylation 67 0.0104 1 0.0143 0.3561500 E PMT6 GO:0006897 6,7 endocytosis 69 0.0107 1 0.0143 0.3588987 E YSC84 GO:0051236 5 establishment of RNA localization 72 0.0112 1 0.0143 0.3624906 E NUP42 GO:0009101 8,7 glycoprotein biosynthesis 72 0.0112 1 0.0143 0.3624906 E PMT6 GO:0006405 10,8,9,7 RNA export from nucleus 72 0.0112 1 0.0143 0.3624906 E NUP42 GO:0050658 7,6,8 RNA transport 72 0.0112 1 0.0143 0.3624906 E NUP42 GO:0050657 6,7 nucleic acid transport 72 0.0112 1 0.0143 0.3624906 E NUP42 GO:0009100 7 glycoprotein metabolism 73 0.0113 1 0.0143 0.3635516 E PMT6 GO:0019236 6 response to pheromone 73 0.0113 1 0.0143 0.3635516 E STE3 GO:0015931 5,6 nucleobase, nucleoside, nucleotide and nucleic acid transport 80 0.0124 1 0.0143 0.3692031 E NUP42 GO:0006403 4 RNA localization 83 0.0129 1 0.0143 0.3707407 E NUP42 GO:0000226 8 microtubule cytoskeleton organization and biogenesis 85 0.0132 1 0.0143 0.3714941 E RRD1 GO:0019318 7,8 hexose metabolism 85 0.0132 1 0.0143 0.3714941 E PCK1 GO:0051168 9,7,8 nuclear export 86 0.0133 1 0.0143 0.3717926 E NUP42 GO:0000154 8 rRNA modification 89 0.0138 1 0.0143 0.3723881 E MRM2 GO:0006812 6,7 cation transport 89 0.0138 1 0.0143 0.3723881 E SMF1 GO:0009117 6 nucleotide metabolism 90 0.0139 1 0.0143 0.3724900 E BNA6 GO:0006468 8 protein amino acid phosphorylation 91 0.0141 1 0.0143 0.3725452 E CHK1 GO:0048622 5 reproductive sporulation 92 0.0143 1 0.0143 0.3725549 E SHC1 GO:0005996 6,7 monosaccharide metabolism 92 0.0143 1 0.0143 0.3725549 E PCK1 GO:0030437 6 sporulation (sensu Fungi) 92 0.0143 1 0.0143 0.3725549 E SHC1 GO:0008150 1 biological_process 6454 1.0000 70 1.0000 1.0000000 D SHC1,ARG3,CTM1,ICS2,OPI3,STE3,MSS51,DPB11,BNA6,SED1,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SMF1,SUM1,CPR5,DIC1,ECM38,COX10,FUM1,YAT2,MSW1,LSB3,SPP1,THI11,CHO2,MRM2,TSA2,SNT2,ABZ1,PST2,CHK1,MIA40,APL3,LYS1,NUP42,PCK1,ICL1,SNA3,PEX28,HRD3,PMT6,CSE2,MRPL19,LRO1,ACP1,TRX2,SGE1,MSU1,DAL5,PST1,CEM1,GCV3,AAC1,GCV1,RER1,COQ5,CDC13,YSC84,GTT1,CPT1,LEU2,BAT2,RMD11,HXT9,AVT5,YSA1 GO:0007005 6 mitochondrion organization and biogenesis 95 0.0147 1 0.0143 0.3723197 D SED1 GO:0007017 7 microtubule-based process 100 0.0155 1 0.0143 0.3711026 D RRD1 GO:0051169 8,6,7 nuclear transport 103 0.0160 1 0.0143 0.3699161 D NUP42 GO:0007059 4 chromosome segregation 104 0.0161 1 0.0143 0.3694495 D CSE2 GO:0030435 4 sporulation 105 0.0163 1 0.0143 0.3689488 D SHC1 GO:0000747 6,4 conjugation with cellular fusion 105 0.0163 1 0.0143 0.3689488 D STE3 GO:0000746 5 conjugation 105 0.0163 1 0.0143 0.3689488 D STE3 GO:0019953 3 sexual reproduction 105 0.0163 1 0.0143 0.3689488 D STE3 GO:0006811 5,6 ion transport 107 0.0166 1 0.0143 0.3678481 D SMF1 GO:0030154 3 cell differentiation 107 0.0166 1 0.0143 0.3678481 D SHC1 GO:0006913 8,6,7 nucleocytoplasmic transport 109 0.0169 1 0.0143 0.3666200 D NUP42 GO:0006511 10,11 ubiquitin-dependent protein catabolism 121 0.0187 1 0.0143 0.3568954 D HRD3 GO:0019941 9,10 modification-dependent protein catabolism 121 0.0187 1 0.0143 0.3568954 D HRD3 GO:0044257 7,8 cellular protein catabolism 123 0.0191 1 0.0143 0.3549314 D HRD3 GO:0051603 8,9 proteolysis during cellular protein catabolism 123 0.0191 1 0.0143 0.3549314 D HRD3 GO:0008380 8 RNA splicing 126 0.0195 1 0.0143 0.3518276 D POA1 GO:0009451 7 RNA modification 126 0.0195 1 0.0143 0.3518276 D MRM2 GO:0016310 7 phosphorylation 143 0.0222 1 0.0143 0.3313191 D CHK1 GO:0030163 6,7 protein catabolism 145 0.0225 1 0.0143 0.3286464 D HRD3 GO:0006461 7 protein complex assembly 148 0.0229 1 0.0143 0.3245581 D COX10 GO:0043285 5,6 biopolymer catabolism 157 0.0243 1 0.0143 0.3118164 D HRD3 GO:0007165 4 signal transduction 167 0.0259 1 0.0143 0.2970506 D STE3 GO:0048610 4 reproductive cellular physiological process 192 0.0297 2 0.0286 0.2755798 D SHC1,STE3 GO:0050876 3 reproductive physiological process 192 0.0297 2 0.0286 0.2755798 D SHC1,STE3 GO:0045045 5,6 secretory pathway 202 0.0313 2 0.0286 0.2735314 D TRX2,RER1 GO:0006323 7 DNA packaging 205 0.0318 2 0.0286 0.2726422 D SUM1,SPP1 GO:0006325 8 establishment and/or maintenance of chromatin architecture 205 0.0318 2 0.0286 0.2726422 D SUM1,SPP1 GO:0046903 5 secretion 209 0.0324 2 0.0286 0.2712732 D TRX2,RER1 GO:0006605 9,7,8 protein targeting 221 0.0342 2 0.0286 0.2660135 D MIA40,NUP42 GO:0006793 5 phosphorus metabolism 188 0.0291 1 0.0143 0.2651325 D CHK1 GO:0006796 6 phosphate metabolism 188 0.0291 1 0.0143 0.2651325 D CHK1 GO:0006886 8,6,7 intracellular protein transport 239 0.0370 2 0.0286 0.2553835 D MIA40,NUP42 GO:0015031 5,6 protein transport 245 0.0380 2 0.0286 0.2512435 D MIA40,NUP42 GO:0007154 3 cell communication 199 0.0308 1 0.0143 0.2484379 D STE3 GO:0000003 2 reproduction 255 0.0395 2 0.0286 0.2438104 D SHC1,STE3 GO:0045184 5 establishment of protein localization 255 0.0395 2 0.0286 0.2438104 D MIA40,NUP42 GO:0044265 6 cellular macromolecule catabolism 258 0.0400 2 0.0286 0.2414671 D HRD3,MSU1 GO:0008104 4 protein localization 285 0.0442 3 0.0429 0.2298766 D MIA40,NUP42,RER1 GO:0007010 6 cytoskeleton organization and biogenesis 290 0.0449 3 0.0429 0.2293575 D RRD1,LSB3,YSC84 GO:0009057 5 macromolecule catabolism 280 0.0434 2 0.0286 0.2230740 D HRD3,MSU1 GO:0006355 8 regulation of transcription, DNA-dependent 305 0.0473 2 0.0286 0.2006221 D SUM1,SPP1 GO:0007275 2 development 373 0.0578 3 0.0429 0.1962626 D SHC1,SUM1,SPP1 GO:0045449 7 regulation of transcription 324 0.0502 2 0.0286 0.1832556 D SUM1,SPP1 GO:0046907 7,5,6 intracellular transport 488 0.0756 5 0.0714 0.1813766 D MIA40,NUP42,TRX2,AAC1,RER1 GO:0051649 6,5 establishment of cellular localization 498 0.0772 5 0.0714 0.1799683 D MIA40,NUP42,TRX2,AAC1,RER1 GO:0031323 5 regulation of cellular metabolism 403 0.0624 3 0.0429 0.1774977 D MSS51,SUM1,SPP1 GO:0051641 5,4 cellular localization 521 0.0807 5 0.0714 0.1753117 D MIA40,NUP42,TRX2,AAC1,RER1 GO:0016072 7 rRNA metabolism 254 0.0394 1 0.0143 0.1718243 D MRM2 GO:0043037 8,7 translation 415 0.0643 3 0.0429 0.1696039 D MSS51,MEF1,MSW1 GO:0006259 6 DNA metabolism 555 0.0860 6 0.0857 0.1688744 D DPB11,NTG1,RRD1,SUM1,SPP1,TRX2 GO:0043412 6 biopolymer modification 567 0.0879 6 0.0857 0.1685196 D CTM1,LAS21,SPP1,MRM2,CHK1,PMT6 GO:0019222 4 regulation of metabolism 429 0.0665 3 0.0429 0.1602727 D MSS51,SUM1,SPP1 GO:0019219 6 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 355 0.0550 2 0.0286 0.1555929 D SUM1,SPP1 GO:0006351 7 transcription, DNA-dependent 441 0.0683 3 0.0429 0.1522489 D SUM1,SPP1,CSE2 GO:0006366 8 transcription from RNA polymerase II promoter 277 0.0429 1 0.0143 0.1447912 D CSE2 GO:0016070 6 RNA metabolism 539 0.0835 4 0.0571 0.1411996 D POA1,MSW1,MRM2,MSU1 GO:0009059 6,5 macromolecule biosynthesis 844 0.1308 8 0.1143 0.1364936 D SHC1,MSS51,LAS21,MEF1,MSW1,PCK1,PMT6,MRPL19 GO:0006996 5 organelle organization and biogenesis 1017 0.1576 10 0.1429 0.1279748 D SED1,RRD1,SUM1,LSB3,SPP1,NUP42,PEX28,TRX2,CDC13,YSC84 GO:0006350 6 transcription 484 0.0750 3 0.0429 0.1241791 D SUM1,SPP1,CSE2 GO:0006414 9,8 translational elongation 312 0.0483 1 0.0143 0.1099493 D MEF1 GO:0043283 5 biopolymer metabolism 1593 0.2468 16 0.2286 0.1064209 D SHC1,CTM1,DPB11,LAS21,POA1,NTG1,RRD1,SUM1,MSW1,SPP1,MRM2,CHK1,HRD3,PMT6,TRX2,MSU1 GO:0006412 7,6 protein biosynthesis 783 0.1213 6 0.0857 0.1062191 D MSS51,LAS21,MEF1,MSW1,PMT6,MRPL19 GO:0016043 4 cell organization and biogenesis 1473 0.2282 14 0.2000 0.1009421 D SED1,RRD1,SUM1,LSB3,SPP1,MIA40,NUP42,PEX28,TRX2,PST1,AAC1,RER1,CDC13,YSC84 GO:0044260 5 cellular macromolecule metabolism 1448 0.2244 13 0.1857 0.0891190 D SHC1,CTM1,MSS51,LAS21,PRD1,MEF1,COX10,MSW1,SPP1,CHK1,HRD3,PMT6,MRPL19 GO:0006396 7 RNA processing 346 0.0536 1 0.0143 0.0829545 D POA1 GO:0044267 6 cellular protein metabolism 1400 0.2169 12 0.1714 0.0800253 D CTM1,MSS51,LAS21,PRD1,MEF1,COX10,MSW1,SPP1,CHK1,HRD3,PMT6,MRPL19 GO:0019538 5 protein metabolism 1424 0.2206 12 0.1714 0.0744002 D CTM1,MSS51,LAS21,PRD1,MEF1,COX10,MSW1,SPP1,CHK1,HRD3,PMT6,MRPL19 GO:0043170 4 macromolecule metabolism 2511 0.3891 24 0.3429 0.0728155 D SHC1,CTM1,MSS51,DPB11,LAS21,POA1,PRD1,NTG1,RRD1,MEF1,SUM1,COX10,FUM1,MSW1,SPP1,MRM2,CHK1,PCK1,ICL1,HRD3,PMT6,MRPL19,TRX2,MSU1 GO:0006139 5 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1500 0.2324 12 0.1714 0.0572629 D DPB11,BNA6,POA1,NTG1,RRD1,SUM1,MSW1,SPP1,MRM2,CSE2,TRX2,MSU1 GO:0000004 2 biological process unknown 1639 0.2540 7 0.1000 0.0007532 D ICS2,CPR5,SNT2,PST2,SNA3,RMD11,YSA1