GO_ID LEVEL(S) TERM NB_IN_REF FREQ_IN_REF NB_IN_SET FREQ_IN_SET P_VALUE ENRICHMENT/DEPLETION GENES_IN_SET GO:0050896 3 response to stimulus 549 0,0851 38 0,2159 3,281205E-08 E ASR1,SIP2,SNF3,GRR1,FRT2,POG1,TPS3,HSP78,PRB1,PHR1,CIN5,SSA4,HOR7,RAD1,CYR1,FAR10,GRE2,GRE3,TSL1,YRR1,LRE1,CTT1,NCE103,MMS4,PHO2,RGT2,YKU70,MEC1,STE18,KIN82,OPY2,MCR1,GLO4,XBP1,RIM11,HSP104,HSP26,ASK10 GO:0005975 5 carbohydrate metabolism 219 0,0339 22 0,1250 7,327717E-08 E MAL33,ADR1,MAL13,TPS3,SOL4,HAP5,VID30,GSY2,GID8,GAL7,FYV10,GRE3,TSL1,GLC3,CIT2,SDH1,GLG1,GLO4,SGA1,UBC8,PCL6,HAP2 GO:0006109 6,5 regulation of carbohydrate metabolism 27 0,0042 8 0,0455 3,510810E-07 E ADR1,HAP5,VID30,GID8,FYV10,UBC8,PCL6,HAP2 GO:0006091 5 generation of precursor metabolites and energy 224 0,0347 20 0,1136 1,855634E-06 E MCT1,NDI1,TPS3,RSF1,SOL4,VID30,GSY2,GID8,FYV10,TSL1,GLC3,COX14,CIT2,ACS1,SDH1,GLG1,MCR1,SGA1,UBC8,PCL6 GO:0015980 6 energy derivation by oxidation of organic compounds 194 0,0301 18 0,1023 3,598907E-06 E MCT1,TPS3,RSF1,SOL4,VID30,GSY2,GID8,FYV10,TSL1,GLC3,COX14,CIT2,ACS1,SDH1,GLG1,SGA1,UBC8,PCL6 GO:0006950 4 response to stress 395 0,0612 27 0,1534 4,883500E-06 E SIP2,FRT2,TPS3,HSP78,PRB1,PHR1,CIN5,SSA4,HOR7,RAD1,CYR1,GRE2,GRE3,TSL1,LRE1,CTT1,NCE103,MMS4,PHO2,YKU70,MEC1,MCR1,XBP1,RIM11,HSP104,HSP26,ASK10 GO:0016051 7,6 carbohydrate biosynthesis 63 0,0098 10 0,0568 5,625209E-06 E TPS3,VID30,GSY2,GID8,FYV10,TSL1,GLC3,GLG1,UBC8,PCL6 GO:0006112 7 energy reserve metabolism 34 0,0053 7 0,0398 2,614338E-05 E TPS3,GSY2,TSL1,GLC3,GLG1,SGA1,PCL6 GO:0007265 7 Ras protein signal transduction 16 0,0025 5 0,0284 4,634498E-05 E TPK2,SHR5,CYR1,TPK1,IRA2 GO:0043255 8,7,6 regulation of carbohydrate biosynthesis 16 0,0025 5 0,0284 4,634498E-05 E VID30,GID8,FYV10,UBC8,PCL6 GO:0045912 7,6 negative regulation of carbohydrate metabolism 9 0,0014 4 0,0227 5,887001E-05 E VID30,GID8,FYV10,UBC8 GO:0045721 11,12,10,9,7,8 negative regulation of gluconeogenesis 9 0,0014 4 0,0227 5,887001E-05 E VID30,GID8,FYV10,UBC8 GO:0044262 6 cellular carbohydrate metabolism 201 0,0311 16 0,0909 7,696446E-05 E TPS3,SOL4,VID30,GSY2,GID8,GAL7,FYV10,GRE3,TSL1,GLC3,CIT2,SDH1,GLG1,SGA1,UBC8,PCL6 GO:0006111 10,11,9,8,7 regulation of gluconeogenesis 11 0,0017 4 0,0227 0,0001461 E VID30,GID8,FYV10,UBC8 GO:0005978 10,9,8 glycogen biosynthesis 11 0,0017 4 0,0227 0,0001461 E GSY2,GLC3,GLG1,PCL6 GO:0009889 5 regulation of biosynthesis 46 0,0071 7 0,0398 0,0001888 E VID30,GID8,FYV10,ECM32,COX14,UBC8,PCL6 GO:0031326 6 regulation of cellular biosynthesis 46 0,0071 7 0,0398 0,0001888 E VID30,GID8,FYV10,ECM32,COX14,UBC8,PCL6 GO:0007582 2 physiological process 4771 0,7392 149 0,8466 0,0002025 E ASR1,HXT7,DAP1,GIP2,UBP15,CBS2,MAL33,GYP7,MEF2,GEM1,ADR1,MTL1,SRY1,SIP2,PPM1,PXA2,MAL13,SNF3,AMA1,MCT1,OAF1,GRR1,FRT2,POG1,TPK2,NDI1,TPS3,HSP78,PRB1,REC114,PEX5,PHR1,CIN5,RSF1,SSA4,HOR7,SHR5,RAD1,CYR1,SOL4,FAR10,HAP5,SYN8,VID30,OCT1,NPR1,MED4,GSY2,GID8,UBX6,BIO3,UGA3,ENA2,GAL7,TPK1,KIN1,PEX2,GRE2,TCO89,MDJ1,FYV10,SWI1,ASM4,ECM32,GRE3,PUT1,ARC35,TSL1,GLC3,NUD1,RCK2,HXT6,HXT16,YRR1,PEX25,PEX22,COX14,LRE1,CIT2,CTT1,YPK1,SNX41,ACS1,NCE103,NVJ1,MMS4,NUT2,PEP12,APM2,PHO2,SSE2,TAD3,RGT2,FMS1,HEM15,YKU70,SDH1,RSE1,VPS30,THI21,MEC1,STE18,KIN82,YPK2,ECM21,ATG7,GLG1,HXT5,PNC1,UBA3,EMI2,PAI3,EMP46,OPY2,INO4,SCP1,MCR1,LTP1,GLO4,ATG12,MPS1,SGA1,MRP8,MRL1,SMF3,DIT1,THI3,ATG19,PIC2,XBP1,TGL4,CRD1,RIM11,GGA1,UBC8,CST9,HSP104,EHT1,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,PPZ2,TRA1,ISU1,APA2,PDX1 GO:0042221 5 response to chemical stimulus 220 0,0341 16 0,0909 0,0002105 E ASR1,SNF3,GRR1,POG1,CIN5,CYR1,FAR10,YRR1,NCE103,RGT2,STE18,KIN82,OPY2,MCR1,GLO4,ASK10 GO:0007031 6 peroxisome organization and biogenesis 37 0,0057 6 0,0341 0,0003833 E ADR1,OAF1,PEX5,PEX2,PEX25,PEX22 GO:0050791 3 regulation of physiological process 584 0,0905 29 0,1648 0,0005453 E MAL33,ADR1,MAL13,OAF1,GRR1,POG1,CIN5,CYR1,FAR10,HAP5,VID30,NPR1,GID8,UGA3,FYV10,ECM32,YRR1,COX14,YKU70,MEC1,PNC1,OPY2,INO4,MPS1,UBC8,PCL6,RAV2,HAP2,TRA1 GO:0005977 8,9 glycogen metabolism 27 0,0042 5 0,0284 0,0006369 E GSY2,GLC3,GLG1,SGA1,PCL6 GO:0007154 3 cell communication 199 0,0308 14 0,0795 0,0006892 E SIP2,SNF3,TPK2,PRB1,RSF1,SHR5,COS111,CYR1,TPK1,RCK2,PHO2,RGT2,STE18,IRA2 GO:0019222 4 regulation of metabolism 429 0,0665 23 0,1307 0,0007436 E MAL33,ADR1,MAL13,OAF1,POG1,CIN5,HAP5,VID30,NPR1,GID8,UGA3,FYV10,ECM32,YRR1,COX14,YKU70,PNC1,INO4,UBC8,PCL6,RAV2,HAP2,TRA1 GO:0050789 2 regulation of biological process 597 0,0925 29 0,1648 0,0007540 E MAL33,ADR1,MAL13,OAF1,GRR1,POG1,CIN5,CYR1,FAR10,HAP5,VID30,NPR1,GID8,UGA3,FYV10,ECM32,YRR1,COX14,YKU70,MEC1,PNC1,OPY2,INO4,MPS1,UBC8,PCL6,RAV2,HAP2,TRA1 GO:0000751 8,6 cell cycle arrest in response to pheromone 8 0,0012 3 0,0170 0,0009749 E GRR1,FAR10,OPY2 GO:0007165 4 signal transduction 167 0,0259 12 0,0682 0,0013347 E SIP2,SNF3,TPK2,RSF1,SHR5,COS111,CYR1,TPK1,RCK2,RGT2,STE18,IRA2 GO:0009250 9,8,7 glucan biosynthesis 19 0,0029 4 0,0227 0,0013815 E GSY2,GLC3,GLG1,PCL6 GO:0007039 7,8 vacuolar protein catabolism 10 0,0015 3 0,0170 0,0019784 E PRB1,VID30,PAI3 GO:0009628 4 response to abiotic stimulus 301 0,0466 17 0,0966 0,0019870 E ASR1,SNF3,GRR1,POG1,CIN5,CYR1,FAR10,YRR1,LRE1,NCE103,RGT2,STE18,KIN82,OPY2,MCR1,GLO4,ASK10 GO:0015749 6,7 monosaccharide transport 21 0,0033 4 0,0227 0,0020207 E HXT7,HXT6,HXT16,HXT5 GO:0008645 7,8 hexose transport 21 0,0033 4 0,0227 0,0020207 E HXT7,HXT6,HXT16,HXT5 GO:0006092 7 main pathways of carbohydrate metabolism 70 0,0108 7 0,0398 0,0022239 E SOL4,VID30,GID8,FYV10,CIT2,SDH1,UBC8 GO:0006468 8 protein amino acid phosphorylation 91 0,0141 8 0,0455 0,0024462 E SIP2,TPK2,TPK1,RCK2,YPK1,KIN82,YPK2,RIM11 GO:0006090 7 pyruvate metabolism 37 0,0057 5 0,0284 0,0026254 E VID30,GID8,FYV10,UBC8,PDX1 GO:0045786 6 negative regulation of progression through cell cycle 11 0,0017 3 0,0170 0,0026473 E GRR1,FAR10,OPY2 GO:0007050 7 cell cycle arrest 11 0,0017 3 0,0170 0,0026473 E GRR1,FAR10,OPY2 GO:0009987 2 cellular process 4682 0,7254 142 0,8068 0,0030488 E HXT7,DAP1,GIP2,UBP15,CBS2,MAL33,GYP7,MEF2,GEM1,ADR1,MTL1,SRY1,SIP2,PPM1,PXA2,MAL13,SNF3,AMA1,MCT1,OAF1,GRR1,POG1,TPK2,NDI1,TPS3,HSP78,PRB1,REC114,PEX5,PHR1,CIN5,RSF1,SSA4,SHR5,COS111,RAD1,CYR1,SOL4,FAR10,HAP5,SYN8,VID30,OCT1,MED4,GSY2,GID8,UBX6,BIO3,UGA3,ENA2,GAL7,TPK1,KIN1,PEX2,TCO89,MDJ1,FYV10,SWI1,ASM4,ECM32,GRE3,PUT1,ARC35,TSL1,GLC3,NUD1,RCK2,HXT6,HXT16,YRR1,PEX25,PEX22,COX14,LRE1,CIT2,YPK1,SNX41,ACS1,NCE103,NVJ1,MMS4,NUT2,PEP12,APM2,PHO2,SSE2,TAD3,RGT2,FMS1,HEM15,YKU70,SDH1,RSE1,VPS30,THI21,MEC1,STE18,KIN82,YPK2,ECM21,ATG7,GLG1,HXT5,PNC1,UBA3,EMI2,EMP46,OPY2,INO4,SCP1,MCR1,LTP1,GLO4,ATG12,MPS1,SGA1,MRP8,MRL1,SMF3,DIT1,THI3,ATG19,PIC2,IRA2,TGL4,CRD1,RIM11,GGA1,UBC8,CST9,HSP104,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,PPZ2,TRA1,ISU1,APA2,PDX1 GO:0006073 7,8 glucan metabolism 39 0,0060 5 0,0284 0,0032854 E GSY2,GLC3,GLG1,SGA1,PCL6 GO:0006793 5 phosphorus metabolism 188 0,0291 12 0,0682 0,0033211 E GIP2,SIP2,TPK2,NDI1,TPK1,RCK2,YPK1,SDH1,KIN82,YPK2,LTP1,RIM11 GO:0006796 6 phosphate metabolism 188 0,0291 12 0,0682 0,0033211 E GIP2,SIP2,TPK2,NDI1,TPK1,RCK2,YPK1,SDH1,KIN82,YPK2,LTP1,RIM11 GO:0016310 7 phosphorylation 143 0,0222 10 0,0568 0,0037780 E SIP2,TPK2,NDI1,TPK1,RCK2,YPK1,SDH1,KIN82,YPK2,RIM11 GO:0042219 7,6 amino acid derivative catabolism 4 0,0006 2 0,0114 0,0042011 E SRY1,FMS1 GO:0006085 8 acetyl-CoA biosynthesis 4 0,0006 2 0,0114 0,0042011 E ACS1,PDX1 GO:0005992 9,8 trehalose biosynthesis 4 0,0006 2 0,0114 0,0042011 E TPS3,TSL1 GO:0046351 8,7 disaccharide biosynthesis 4 0,0006 2 0,0114 0,0042011 E TPS3,TSL1 GO:0009267 5,6 cellular response to starvation 13 0,0020 3 0,0170 0,0043455 E SIP2,PRB1,PHO2 GO:0042594 5 response to starvation 13 0,0020 3 0,0170 0,0043455 E SIP2,PRB1,PHO2 GO:0006094 9,10,8 gluconeogenesis 26 0,0040 4 0,0227 0,0044076 E VID30,GID8,FYV10,UBC8 GO:0019740 5 nitrogen utilization 14 0,0022 3 0,0170 0,0053821 E VID30,NPR1,UGA3 GO:0019319 8,9 hexose biosynthesis 28 0,0043 4 0,0227 0,0057178 E VID30,GID8,FYV10,UBC8 GO:0046364 7,8 monosaccharide biosynthesis 28 0,0043 4 0,0227 0,0057178 E VID30,GID8,FYV10,UBC8 GO:0000271 8,7,6 polysaccharide biosynthesis 28 0,0043 4 0,0227 0,0057178 E GSY2,GLC3,GLG1,PCL6 GO:0043284 7,5,6 biopolymer biosynthesis 28 0,0043 4 0,0227 0,0057178 E GSY2,GLC3,GLG1,PCL6 GO:0006625 10,7,8,9 protein targeting to peroxisome 15 0,0023 3 0,0170 0,0065469 E PEX5,PEX25,PEX22 GO:0009749 8,7 response to glucose stimulus 5 0,0008 2 0,0114 0,0068130 E SNF3,RGT2 GO:0009746 7,6 response to hexose stimulus 5 0,0008 2 0,0114 0,0068130 E SNF3,RGT2 GO:0006066 5 alcohol metabolism 157 0,0243 10 0,0568 0,0068137 E DAP1,SOL4,VID30,GID8,GAL7,TCO89,FYV10,GRE3,MCR1,UBC8 GO:0046165 6 alcohol biosynthesis 30 0,0046 4 0,0227 0,0072488 E VID30,GID8,FYV10,UBC8 GO:0006457 7 protein folding 67 0,0104 6 0,0341 0,0073389 E HSP78,SSA4,MDJ1,SSE2,HSP104,HSP26 GO:0051244 4 regulation of cellular physiological process 566 0,0877 24 0,1364 0,0086308 E MAL33,MAL13,OAF1,GRR1,POG1,CIN5,CYR1,FAR10,VID30,GID8,UGA3,FYV10,ECM32,YRR1,COX14,YKU70,MEC1,PNC1,OPY2,INO4,MPS1,UBC8,PCL6,TRA1 GO:0050794 3 regulation of cellular process 568 0,0880 24 0,1364 0,0089303 E MAL33,MAL13,OAF1,GRR1,POG1,CIN5,CYR1,FAR10,VID30,GID8,UGA3,FYV10,ECM32,YRR1,COX14,YKU70,MEC1,PNC1,OPY2,INO4,MPS1,UBC8,PCL6,TRA1 GO:0005996 6,7 monosaccharide metabolism 92 0,0143 7 0,0398 0,0089979 E SOL4,VID30,GID8,GAL7,FYV10,GRE3,UBC8 GO:0051179 3 localization 991 0,1535 37 0,2102 0,0096337 E HXT7,GYP7,GEM1,PXA2,NDI1,HSP78,PEX5,SSA4,SHR5,SYN8,OCT1,ENA2,KIN1,ASM4,ARC35,HXT6,HXT16,YRR1,PEX25,PEX22,YPK1,SNX41,PEP12,APM2,SDH1,VPS30,ATG7,HXT5,EMP46,MCR1,ATG12,MRL1,SMF3,ATG19,PIC2,GGA1,RAV2 GO:0009743 6,5 response to carbohydrate stimulus 6 0,0009 2 0,0114 0,0099437 E SNF3,RGT2 GO:0050875 3 cellular physiological process 4641 0,7191 138 0,7841 0,0100542 E HXT7,DAP1,GIP2,UBP15,CBS2,MAL33,GYP7,MEF2,GEM1,ADR1,MTL1,SRY1,SIP2,PPM1,PXA2,MAL13,AMA1,MCT1,OAF1,GRR1,POG1,TPK2,NDI1,TPS3,HSP78,PRB1,REC114,PEX5,PHR1,CIN5,RSF1,SSA4,SHR5,RAD1,CYR1,SOL4,FAR10,HAP5,SYN8,VID30,OCT1,MED4,GSY2,GID8,UBX6,BIO3,UGA3,ENA2,GAL7,TPK1,KIN1,PEX2,TCO89,MDJ1,FYV10,SWI1,ASM4,ECM32,GRE3,PUT1,ARC35,TSL1,GLC3,NUD1,RCK2,HXT6,HXT16,YRR1,PEX25,PEX22,COX14,LRE1,CIT2,YPK1,SNX41,ACS1,NCE103,NVJ1,MMS4,NUT2,PEP12,APM2,PHO2,SSE2,TAD3,FMS1,HEM15,YKU70,SDH1,RSE1,VPS30,THI21,MEC1,STE18,KIN82,YPK2,ECM21,ATG7,GLG1,HXT5,PNC1,UBA3,EMI2,EMP46,OPY2,INO4,SCP1,MCR1,LTP1,GLO4,ATG12,MPS1,SGA1,MRP8,MRL1,SMF3,DIT1,THI3,ATG19,PIC2,TGL4,CRD1,RIM11,GGA1,UBC8,CST9,HSP104,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,PPZ2,TRA1,ISU1,APA2,PDX1 GO:0019236 6 response to pheromone 73 0,0113 6 0,0341 0,0106472 E GRR1,POG1,FAR10,STE18,KIN82,OPY2 GO:0008643 5,6 carbohydrate transport 34 0,0053 4 0,0227 0,0110045 E HXT7,HXT6,HXT16,HXT5 GO:0044264 6,7 cellular polysaccharide metabolism 53 0,0082 5 0,0284 0,0112136 E GSY2,GLC3,GLG1,SGA1,PCL6 GO:0005976 6 polysaccharide metabolism 53 0,0082 5 0,0284 0,0112136 E GSY2,GLC3,GLG1,SGA1,PCL6 GO:0051186 5 cofactor metabolism 148 0,0229 9 0,0511 0,0124704 E SOL4,BIO3,ACS1,FMS1,HEM15,SDH1,PNC1,ISU1,PDX1 GO:0031323 5 regulation of cellular metabolism 403 0,0624 18 0,1023 0,0125002 E MAL33,MAL13,OAF1,POG1,CIN5,VID30,GID8,UGA3,FYV10,ECM32,YRR1,COX14,YKU70,PNC1,INO4,UBC8,PCL6,TRA1 GO:0007264 6 small GTPase mediated signal transduction 55 0,0085 5 0,0284 0,0128770 E TPK2,SHR5,CYR1,TPK1,IRA2 GO:0006914 4 autophagy 36 0,0056 4 0,0227 0,0132385 E NVJ1,VPS30,ATG7,ATG12 GO:0005991 8 trehalose metabolism 7 0,0011 2 0,0114 0,0135455 E TPS3,TSL1 GO:0005980 10,9 glycogen catabolism 7 0,0011 2 0,0114 0,0135455 E SGA1,PCL6 GO:0007127 8 meiosis I 56 0,0087 5 0,0284 0,0137616 E AMA1,REC114,MMS4,MEC1,CST9 GO:0006810 4,5 transport 924 0,1432 34 0,1932 0,0141731 E HXT7,GYP7,GEM1,PXA2,NDI1,HSP78,PEX5,SSA4,SYN8,OCT1,ENA2,KIN1,ASM4,HXT6,HXT16,YRR1,PEX25,PEX22,YPK1,SNX41,PEP12,APM2,SDH1,VPS30,ATG7,HXT5,EMP46,MCR1,ATG12,MRL1,ATG19,PIC2,GGA1,RAV2 GO:0009991 4,5 response to extracellular stimulus 20 0,0031 3 0,0170 0,0143143 E SIP2,PRB1,PHO2 GO:0006084 7 acetyl-CoA metabolism 20 0,0031 3 0,0170 0,0143143 E ACS1,SDH1,PDX1 GO:0030435 4 sporulation 105 0,0163 7 0,0398 0,0164682 E AMA1,PRB1,UBX6,EMI2,SGA1,DIT1,RIM11 GO:0051234 4 establishment of localization 942 0,1460 34 0,1932 0,0172917 E HXT7,GYP7,GEM1,PXA2,NDI1,HSP78,PEX5,SSA4,SYN8,OCT1,ENA2,KIN1,ASM4,HXT6,HXT16,YRR1,PEX25,PEX22,YPK1,SNX41,PEP12,APM2,SDH1,VPS30,ATG7,HXT5,EMP46,MCR1,ATG12,MRL1,ATG19,PIC2,GGA1,RAV2 GO:0006808 6 regulation of nitrogen utilization 8 0,0012 2 0,0114 0,0175732 E VID30,NPR1 GO:0051171 5 regulation of nitrogen metabolism 8 0,0012 2 0,0114 0,0175732 E VID30,NPR1 GO:0030154 3 cell differentiation 107 0,0166 7 0,0398 0,0178757 E AMA1,PRB1,UBX6,EMI2,SGA1,DIT1,RIM11 GO:0015031 5,6 protein transport 245 0,0380 12 0,0682 0,0189956 E HSP78,PEX5,SSA4,OCT1,ASM4,PEX25,PEX22,SNX41,VPS30,ATG7,ATG12,ATG19 GO:0019318 7,8 hexose metabolism 85 0,0132 6 0,0341 0,0197779 E SOL4,VID30,GID8,GAL7,FYV10,UBC8 GO:0007569 5,4 cell aging 41 0,0064 4 0,0227 0,0198683 E SIP2,CYR1,PNC1,SCP1 GO:0006464 7 protein modification 431 0,0668 18 0,1023 0,0204442 E GIP2,UBP15,SIP2,PPM1,GRR1,TPK2,SHR5,OCT1,TPK1,RCK2,YPK1,KIN82,YPK2,UBA3,LTP1,RIM11,UBC8,TRA1 GO:0009056 4 catabolism 369 0,0572 16 0,0909 0,0205712 E SRY1,AMA1,GRR1,PRB1,REC114,SOL4,VID30,UBX6,GRE3,PUT1,FMS1,SDH1,PAI3,GLO4,SGA1,PCL6 GO:0050876 3 reproductive physiological process 192 0,0297 10 0,0568 0,0210747 E AMA1,GRR1,POG1,FAR10,STE18,EMI2,OPY2,SGA1,DIT1,RIM11 GO:0048610 4 reproductive cellular physiological process 192 0,0297 10 0,0568 0,0210747 E AMA1,GRR1,POG1,FAR10,STE18,EMI2,OPY2,SGA1,DIT1,RIM11 GO:0006605 9,7,8 protein targeting 221 0,0342 11 0,0625 0,0213434 E HSP78,PEX5,SSA4,OCT1,ASM4,PEX25,PEX22,VPS30,ATG7,ATG12,ATG19 GO:0007568 3,4 aging 42 0,0065 4 0,0227 0,0213707 E SIP2,CYR1,PNC1,SCP1 GO:0009251 9,8 glucan catabolism 9 0,0014 2 0,0114 0,0219843 E SGA1,PCL6 GO:0000074 5 regulation of progression through cell cycle 140 0,0217 8 0,0455 0,0230461 E GRR1,POG1,CYR1,FAR10,GID8,MEC1,OPY2,MPS1 GO:0006006 8,9 glucose metabolism 65 0,0101 5 0,0284 0,0233156 E SOL4,VID30,GID8,FYV10,UBC8 GO:0045184 5 establishment of protein localization 255 0,0395 12 0,0682 0,0237431 E HSP78,PEX5,SSA4,OCT1,ASM4,PEX25,PEX22,SNX41,VPS30,ATG7,ATG12,ATG19 GO:0008104 4 protein localization 285 0,0442 13 0,0739 0,0237514 E HSP78,PEX5,SSA4,SHR5,OCT1,ASM4,PEX25,PEX22,SNX41,VPS30,ATG7,ATG12,ATG19 GO:0051243 5 negative regulation of cellular physiological process 170 0,0263 9 0,0511 0,0248241 E GRR1,FAR10,VID30,GID8,FYV10,YKU70,PNC1,OPY2,UBC8 GO:0048523 4 negative regulation of cellular process 170 0,0263 9 0,0511 0,0248241 E GRR1,FAR10,VID30,GID8,FYV10,YKU70,PNC1,OPY2,UBC8 GO:0043118 4 negative regulation of physiological process 172 0,0267 9 0,0511 0,0261998 E GRR1,FAR10,VID30,GID8,FYV10,YKU70,PNC1,OPY2,UBC8 GO:0001300 6,5 chronological cell aging 10 0,0015 2 0,0114 0,0267384 E CYR1,SCP1 GO:0051085 9 chaperone cofactor dependent protein folding 1 0,0002 1 0,0057 0,0272699 E HSP104 GO:0045471 7 response to ethanol 1 0,0002 1 0,0057 0,0272699 E ASR1 GO:0019654 8 acetate fermentation 1 0,0002 1 0,0057 0,0272699 E ACS1 GO:0006120 9,11,8 mitochondrial electron transport, NADH to ubiquinone 1 0,0002 1 0,0057 0,0272699 E NDI1 GO:0018410 8 peptide or protein carboxyl-terminal blocking 1 0,0002 1 0,0057 0,0272699 E PPM1 GO:0006481 9,10 C-terminal protein amino acid methylation 1 0,0002 1 0,0057 0,0272699 E PPM1 GO:0000719 9,8 photoreactive repair 1 0,0002 1 0,0057 0,0272699 E PHR1 GO:0006290 8,7 pyrimidine dimer repair 1 0,0002 1 0,0057 0,0272699 E PHR1 GO:0010033 6 response to organic substance 1 0,0002 1 0,0057 0,0272699 E ASR1 GO:0006350 6 transcription 484 0,0750 19 0,1080 0,0277870 E MAL33,ADR1,MAL13,OAF1,POG1,CIN5,RSF1,HAP5,MED4,UGA3,YRR1,NUT2,PHO2,YKU70,PNC1,INO4,ASK10,HAP2,TRA1 GO:0008219 4 cell death 46 0,0071 4 0,0227 0,0279451 E SIP2,CYR1,PNC1,SCP1 GO:0016265 3 death 47 0,0073 4 0,0227 0,0297248 E SIP2,CYR1,PNC1,SCP1 GO:0009605 4 response to external stimulus 27 0,0042 3 0,0170 0,0303452 E SIP2,PRB1,PHO2 GO:0048519 3 negative regulation of biological process 178 0,0276 9 0,0511 0,0305669 E GRR1,FAR10,VID30,GID8,FYV10,YKU70,PNC1,OPY2,UBC8 GO:0006082 5 organic acid metabolism 300 0,0465 13 0,0739 0,0313876 E MCT1,OAF1,VID30,GID8,BIO3,FYV10,PUT1,CIT2,ACS1,PHO2,GLO4,UBC8,PDX1 GO:0019752 6 carboxylic acid metabolism 300 0,0465 13 0,0739 0,0313876 E MCT1,OAF1,VID30,GID8,BIO3,FYV10,PUT1,CIT2,ACS1,PHO2,GLO4,UBC8,PDX1 GO:0007034 8,6,7 vacuolar transport 48 0,0074 4 0,0227 0,0315565 E PEP12,MRL1,GGA1,RAV2 GO:0006886 8,6,7 intracellular protein transport 239 0,0370 11 0,0625 0,0317471 E HSP78,PEX5,SSA4,OCT1,ASM4,PEX25,PEX22,VPS30,ATG7,ATG12,ATG19 GO:0006766 5 vitamin metabolism 74 0,0115 5 0,0284 0,0356145 E SOL4,BIO3,THI21,PNC1,THI3 GO:0006767 6 water-soluble vitamin metabolism 74 0,0115 5 0,0284 0,0356145 E SOL4,BIO3,THI21,PNC1,THI3 GO:0006879 8,9 iron ion homeostasis 29 0,0045 3 0,0170 0,0358947 E OCT1,SMF3,ISU1 GO:0044247 8,7 cellular polysaccharide catabolism 12 0,0019 2 0,0114 0,0371270 E SGA1,PCL6 GO:0000272 6,7 polysaccharide catabolism 12 0,0019 2 0,0114 0,0371270 E SGA1,PCL6 GO:0043285 5,6 biopolymer catabolism 157 0,0243 8 0,0455 0,0372516 E AMA1,GRR1,PRB1,VID30,UBX6,PAI3,SGA1,PCL6 GO:0051321 5 meiotic cell cycle 129 0,0200 7 0,0398 0,0378022 E AMA1,REC114,CYR1,RCK2,MMS4,MEC1,CST9 GO:0007126 7 meiosis 129 0,0200 7 0,0398 0,0378022 E AMA1,REC114,CYR1,RCK2,MMS4,MEC1,CST9 GO:0051327 6 M phase of meiotic cell cycle 129 0,0200 7 0,0398 0,0378022 E AMA1,REC114,CYR1,RCK2,MMS4,MEC1,CST9 GO:0006979 6,5 response to oxidative stress 52 0,0081 4 0,0227 0,0393757 E CYR1,NCE103,MCR1,ASK10 GO:0000749 7,5 response to pheromone during conjugation with cellular fusion 53 0,0082 4 0,0227 0,0414457 E GRR1,FAR10,STE18,OPY2 GO:0006118 6,5 electron transport 31 0,0048 3 0,0170 0,0418101 E NDI1,SDH1,MCR1 GO:0006537 9,10 glutamate biosynthesis 13 0,0020 2 0,0114 0,0426922 E PUT1,CIT2 GO:0008152 3 metabolism 3427 0,5310 99 0,5625 0,0427340 E DAP1,GIP2,UBP15,CBS2,MAL33,MEF2,ADR1,SRY1,SIP2,PPM1,MAL13,AMA1,MCT1,OAF1,GRR1,POG1,TPK2,NDI1,TPS3,HSP78,PRB1,REC114,PHR1,CIN5,RSF1,SSA4,SHR5,RAD1,CYR1,SOL4,HAP5,VID30,OCT1,NPR1,MED4,GSY2,GID8,UBX6,BIO3,UGA3,GAL7,TPK1,TCO89,MDJ1,FYV10,SWI1,ECM32,GRE3,PUT1,TSL1,GLC3,RCK2,YRR1,COX14,CIT2,YPK1,ACS1,NCE103,MMS4,NUT2,PHO2,SSE2,TAD3,FMS1,HEM15,YKU70,SDH1,RSE1,THI21,MEC1,KIN82,YPK2,GLG1,PNC1,UBA3,PAI3,INO4,MCR1,LTP1,GLO4,SGA1,MRP8,THI3,TGL4,CRD1,RIM11,UBC8,HSP104,EHT1,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,TRA1,ISU1,APA2,PDX1 GO:0006800 5 oxygen and reactive oxygen species metabolism 54 0,0084 4 0,0227 0,0435586 E CYR1,NCE103,MCR1,ASK10 GO:0007242 5 intracellular signaling cascade 107 0,0166 6 0,0341 0,0450235 E TPK2,RSF1,SHR5,CYR1,TPK1,IRA2 GO:0010133 10,9,11 proline catabolism to glutamate 2 0,0003 1 0,0057 0,0530607 E PUT1 GO:0051238 5 sequestering of metal ion 2 0,0003 1 0,0057 0,0530607 E SMF3 GO:0019365 9,7,8 pyridine nucleotide salvage 2 0,0003 1 0,0057 0,0530607 E PNC1 GO:0019358 10,8,9 nicotinate nucleotide salvage 2 0,0003 1 0,0057 0,0530607 E PNC1 GO:0006642 9,8,10 triacylglycerol mobilization 2 0,0003 1 0,0057 0,0530607 E TGL4 GO:0051084 8 posttranslational protein folding 2 0,0003 1 0,0057 0,0530607 E HSP104 GO:0046497 9,8 nicotinate nucleotide metabolism 2 0,0003 1 0,0057 0,0530607 E PNC1 GO:0043173 6 nucleotide salvage 2 0,0003 1 0,0057 0,0530607 E PNC1 GO:0042149 6,7 cellular response to glucose starvation 2 0,0003 1 0,0057 0,0530607 E SIP2 GO:0006086 9,8 acetyl-CoA biosynthesis from pyruvate 2 0,0003 1 0,0057 0,0530607 E PDX1 GO:0006880 9,10,6 intracellular sequestering of iron ion 2 0,0003 1 0,0057 0,0530607 E SMF3 GO:0000736 10,9 double-strand break repair via single-strand annealing, removal of nonhomologous ends 2 0,0003 1 0,0057 0,0530607 E RAD1 GO:0006623 10,8,9 protein targeting to vacuole 59 0,0091 4 0,0227 0,0547014 E VPS30,ATG7,ATG12,ATG19 GO:0006875 7 metal ion homeostasis 60 0,0093 4 0,0227 0,0570323 E OCT1,SMF3,PPZ2,ISU1 GO:0044237 4 cellular metabolism 3376 0,5231 94 0,5341 0,0584090 E DAP1,GIP2,UBP15,CBS2,MAL33,MEF2,ADR1,SRY1,SIP2,PPM1,MAL13,MCT1,OAF1,GRR1,POG1,TPK2,NDI1,TPS3,HSP78,REC114,PHR1,CIN5,RSF1,SSA4,SHR5,RAD1,CYR1,SOL4,HAP5,VID30,OCT1,MED4,GSY2,GID8,UBX6,BIO3,UGA3,GAL7,TPK1,TCO89,MDJ1,FYV10,SWI1,ECM32,GRE3,PUT1,TSL1,GLC3,RCK2,YRR1,COX14,CIT2,YPK1,ACS1,NCE103,MMS4,NUT2,PHO2,SSE2,TAD3,FMS1,HEM15,YKU70,SDH1,RSE1,THI21,MEC1,KIN82,YPK2,GLG1,PNC1,UBA3,INO4,MCR1,LTP1,GLO4,SGA1,MRP8,THI3,TGL4,CRD1,RIM11,UBC8,HSP104,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,TRA1,ISU1,APA2,PDX1 GO:0044238 4 primary metabolism 3152 0,4884 87 0,4943 0,0601252 E DAP1,GIP2,UBP15,CBS2,MAL33,MEF2,ADR1,SRY1,SIP2,PPM1,MAL13,AMA1,MCT1,OAF1,GRR1,POG1,TPK2,TPS3,HSP78,PRB1,REC114,PHR1,CIN5,RSF1,SSA4,SHR5,RAD1,SOL4,HAP5,VID30,OCT1,MED4,GSY2,GID8,UBX6,UGA3,GAL7,TPK1,MDJ1,FYV10,SWI1,ECM32,GRE3,PUT1,TSL1,GLC3,RCK2,YRR1,COX14,CIT2,YPK1,MMS4,NUT2,PHO2,SSE2,TAD3,FMS1,YKU70,SDH1,RSE1,MEC1,KIN82,YPK2,GLG1,PNC1,UBA3,PAI3,INO4,MCR1,LTP1,GLO4,SGA1,MRP8,TGL4,CRD1,RIM11,UBC8,HSP104,EHT1,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,TRA1,APA2 GO:0006536 8,9 glutamate metabolism 16 0,0025 2 0,0114 0,0604991 E PUT1,CIT2 GO:0044248 5 cellular catabolism 347 0,0538 13 0,0739 0,0608341 E SRY1,GRR1,REC114,SOL4,VID30,UBX6,GRE3,PUT1,FMS1,SDH1,GLO4,SGA1,PCL6 GO:0030003 6 cation homeostasis 89 0,0138 5 0,0284 0,0610254 E OCT1,SMF3,RAV2,PPZ2,ISU1 GO:0006732 6 coenzyme metabolism 119 0,0184 6 0,0341 0,0623951 E SOL4,ACS1,FMS1,SDH1,PNC1,PDX1 GO:0043412 6 biopolymer modification 567 0,0879 19 0,1080 0,0638958 E GIP2,UBP15,SIP2,PPM1,GRR1,TPK2,SHR5,OCT1,TPK1,RCK2,YPK1,TAD3,KIN82,YPK2,UBA3,LTP1,RIM11,UBC8,TRA1 GO:0042364 7 water-soluble vitamin biosynthesis 38 0,0059 3 0,0170 0,0648102 E BIO3,THI21,THI3 GO:0009110 6 vitamin biosynthesis 38 0,0059 3 0,0170 0,0648102 E BIO3,THI21,THI3 GO:0030437 6 sporulation (sensu Fungi) 92 0,0143 5 0,0284 0,0666282 E AMA1,EMI2,SGA1,DIT1,RIM11 GO:0048622 5 reproductive sporulation 92 0,0143 5 0,0284 0,0666282 E AMA1,EMI2,SGA1,DIT1,RIM11 GO:0007131 9,8 meiotic recombination 39 0,0060 3 0,0170 0,0683179 E REC114,MMS4,MEC1 GO:0045941 8 positive regulation of transcription 65 0,0101 4 0,0227 0,0690889 E OAF1,UGA3,YRR1,INO4 GO:0000003 2 reproduction 255 0,0395 10 0,0568 0,0697021 E AMA1,GRR1,POG1,FAR10,STE18,EMI2,OPY2,SGA1,DIT1,RIM11 GO:0006629 5 lipid metabolism 222 0,0344 9 0,0511 0,0706987 E DAP1,MCT1,OAF1,YPK1,INO4,MCR1,TGL4,CRD1,EHT1 GO:0045935 7 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 66 0,0102 4 0,0227 0,0715663 E OAF1,UGA3,YRR1,INO4 GO:0007166 5 cell surface receptor linked signal transduction 40 0,0062 3 0,0170 0,0718654 E CYR1,RCK2,STE18 GO:0006896 10,9,8,7 Golgi to vacuole transport 18 0,0028 2 0,0114 0,0730228 E PEP12,GGA1 GO:0009893 5 positive regulation of metabolism 68 0,0105 4 0,0227 0,0765706 E OAF1,UGA3,YRR1,INO4 GO:0031325 6 positive regulation of cellular metabolism 68 0,0105 4 0,0227 0,0765706 E OAF1,UGA3,YRR1,INO4 GO:0051641 5,4 cellular localization 521 0,0807 17 0,0966 0,0769962 E HSP78,PEX5,SSA4,OCT1,ASM4,ARC35,PEX25,PEX22,PEP12,VPS30,ATG7,EMP46,ATG12,MRL1,ATG19,GGA1,RAV2 GO:0006883 8 sodium ion homeostasis 3 0,0005 1 0,0057 0,0774323 E PPZ2 GO:0000067 5 DNA replication and chromosome cycle 3 0,0005 1 0,0057 0,0774323 E CST9 GO:0018345 10,9 protein palmitoylation 3 0,0005 1 0,0057 0,0774323 E SHR5 GO:0009051 11,12,13,9 pentose-phosphate shunt, oxidative branch 3 0,0005 1 0,0057 0,0774323 E SOL4 GO:0043254 8,7,6 regulation of protein complex assembly 3 0,0005 1 0,0057 0,0774323 E RAV2 GO:0006390 8 transcription from mitochondrial promoter 3 0,0005 1 0,0057 0,0774323 E RSF1 GO:0000320 6 re-entry into mitotic cell cycle 3 0,0005 1 0,0057 0,0774323 E POG1 GO:0009438 6 methylglyoxal metabolism 3 0,0005 1 0,0057 0,0774323 E GLO4 GO:0006449 10,9,8 regulation of translational termination 3 0,0005 1 0,0057 0,0774323 E ECM32 GO:0019243 8 methylglyoxal catabolism to D-lactate 3 0,0005 1 0,0057 0,0774323 E GLO4 GO:0018318 11,10 protein amino acid palmitoylation 3 0,0005 1 0,0057 0,0774323 E SHR5 GO:0051596 7 methylglyoxal catabolism 3 0,0005 1 0,0057 0,0774323 E GLO4 GO:0000321 7,8,6 re-entry into mitotic cell cycle after pheromone arrest 3 0,0005 1 0,0057 0,0774323 E POG1 GO:0006598 8,9 polyamine catabolism 3 0,0005 1 0,0057 0,0774323 E FMS1 GO:0051595 7 response to methylglyoxal 3 0,0005 1 0,0057 0,0774323 E GLO4 GO:0042402 7,8 biogenic amine catabolism 3 0,0005 1 0,0057 0,0774323 E FMS1 GO:0006814 8,9 sodium ion transport 3 0,0005 1 0,0057 0,0774323 E ENA2 GO:0016036 6,7 cellular response to phosphate starvation 3 0,0005 1 0,0057 0,0774323 E PHO2 GO:0006873 5 cell ion homeostasis 98 0,0152 5 0,0284 0,0781284 E OCT1,SMF3,RAV2,PPZ2,ISU1 GO:0007275 2 development 373 0,0578 13 0,0739 0,0781507 E SIP2,AMA1,PRB1,RAD1,CYR1,UBX6,YKU70,PNC1,EMI2,SCP1,SGA1,DIT1,RIM11 GO:0006081 5 aldehyde metabolism 19 0,0029 2 0,0114 0,0794073 E CIT2,GLO4 GO:0009228 8,9 thiamin biosynthesis 19 0,0029 2 0,0114 0,0794073 E THI21,THI3 GO:0046907 7,5,6 intracellular transport 488 0,0756 16 0,0909 0,0794436 E HSP78,PEX5,SSA4,OCT1,ASM4,PEX25,PEX22,PEP12,VPS30,ATG7,EMP46,ATG12,MRL1,ATG19,GGA1,RAV2 GO:0051649 6,5 establishment of cellular localization 498 0,0772 16 0,0909 0,0841491 E HSP78,PEX5,SSA4,OCT1,ASM4,PEX25,PEX22,PEP12,VPS30,ATG7,EMP46,ATG12,MRL1,ATG19,GGA1,RAV2 GO:0043119 4 positive regulation of physiological process 71 0,0110 4 0,0227 0,0841699 E OAF1,UGA3,YRR1,INO4 GO:0051242 5 positive regulation of cellular physiological process 71 0,0110 4 0,0227 0,0841699 E OAF1,UGA3,YRR1,INO4 GO:0048522 4 positive regulation of cellular process 71 0,0110 4 0,0227 0,0841699 E OAF1,UGA3,YRR1,INO4 GO:0016052 6 carbohydrate catabolism 71 0,0110 4 0,0227 0,0841699 E SOL4,GRE3,SGA1,PCL6 GO:0044275 7 cellular carbohydrate catabolism 71 0,0110 4 0,0227 0,0841699 E SOL4,GRE3,SGA1,PCL6 GO:0042724 8 thiamin and derivative biosynthesis 20 0,0031 2 0,0114 0,0858446 E THI21,THI3 GO:0006772 8 thiamin metabolism 20 0,0031 2 0,0114 0,0858446 E THI21,THI3 GO:0050801 4 ion homeostasis 102 0,0158 5 0,0284 0,0859178 E OCT1,SMF3,RAV2,PPZ2,ISU1 GO:0009057 5 macromolecule catabolism 280 0,0434 10 0,0568 0,0914422 E AMA1,GRR1,PRB1,SOL4,VID30,UBX6,GRE3,PAI3,SGA1,PCL6 GO:0019953 3 sexual reproduction 105 0,0163 5 0,0284 0,0917743 E GRR1,POG1,FAR10,STE18,OPY2 GO:0000746 5 conjugation 105 0,0163 5 0,0284 0,0917743 E GRR1,POG1,FAR10,STE18,OPY2 GO:0000747 6,4 conjugation with cellular fusion 105 0,0163 5 0,0284 0,0917743 E GRR1,POG1,FAR10,STE18,OPY2 GO:0044255 5,6 cellular lipid metabolism 208 0,0322 8 0,0455 0,0926025 E DAP1,MCT1,OAF1,YPK1,INO4,MCR1,TGL4,CRD1 GO:0007049 4 cell cycle 397 0,0615 13 0,0739 0,0926534 E AMA1,GRR1,POG1,REC114,CYR1,FAR10,GID8,RCK2,MMS4,MEC1,OPY2,MPS1,CST9 GO:0051246 6,5 regulation of protein metabolism 46 0,0071 3 0,0170 0,0937039 E ECM32,COX14,RAV2 GO:0045449 7 regulation of transcription 324 0,0502 11 0,0625 0,0959560 E MAL33,MAL13,OAF1,POG1,CIN5,UGA3,YRR1,YKU70,PNC1,INO4,TRA1 GO:0046916 8 transition metal ion homeostasis 47 0,0073 3 0,0170 0,0973905 E OCT1,SMF3,ISU1 GO:0019725 4 cell homeostasis 108 0,0167 5 0,0284 0,0976107 E OCT1,SMF3,RAV2,PPZ2,ISU1 GO:0042723 7 thiamin and derivative metabolism 22 0,0034 2 0,0114 0,0987998 E THI21,THI3 GO:0019566 8,9 arabinose metabolism 4 0,0006 1 0,0057 0,1004424 E GRE3 GO:0042843 9,10 D-xylose catabolism 4 0,0006 1 0,0057 0,1004424 E GRE3 GO:0006101 9,7 citrate metabolism 4 0,0006 1 0,0057 0,1004424 E CIT2 GO:0006662 5 glycerol ether metabolism 4 0,0006 1 0,0057 0,1004424 E TGL4 GO:0006562 9,10 proline catabolism 4 0,0006 1 0,0057 0,1004424 E PUT1 GO:0006097 7,8 glyoxylate cycle 4 0,0006 1 0,0057 0,1004424 E CIT2 GO:0009102 7,8 biotin biosynthesis 4 0,0006 1 0,0057 0,1004424 E BIO3 GO:0005981 11,10,6 regulation of glycogen catabolism 4 0,0006 1 0,0057 0,1004424 E PCL6 GO:0007187 7,8 G-protein signaling, coupled to cyclic nucleotide second messenger 4 0,0006 1 0,0057 0,1004424 E CYR1 GO:0006121 9,11,8 mitochondrial electron transport, succinate to ubiquinone 4 0,0006 1 0,0057 0,1004424 E SDH1 GO:0042732 8,9 D-xylose metabolism 4 0,0006 1 0,0057 0,1004424 E GRE3 GO:0015908 6,7 fatty acid transport 4 0,0006 1 0,0057 0,1004424 E PXA2 GO:0000735 10,7 removal of nonhomologous ends 4 0,0006 1 0,0057 0,1004424 E RAD1 GO:0006638 6,7 neutral lipid metabolism 4 0,0006 1 0,0057 0,1004424 E TGL4 GO:0046487 6,7 glyoxylate metabolism 4 0,0006 1 0,0057 0,1004424 E CIT2 GO:0046486 6,7 glycerolipid metabolism 4 0,0006 1 0,0057 0,1004424 E TGL4 GO:0016478 10,9,8 negative regulation of translation 4 0,0006 1 0,0057 0,1004424 E COX14 GO:0000059 11,9,8,10 protein import into nucleus, docking 4 0,0006 1 0,0057 0,1004424 E ASM4 GO:0007188 8,9 G-protein signaling, coupled to cAMP nucleotide second messenger 4 0,0006 1 0,0057 0,1004424 E CYR1 GO:0019568 9,10 arabinose catabolism 4 0,0006 1 0,0057 0,1004424 E GRE3 GO:0006768 6,7 biotin metabolism 4 0,0006 1 0,0057 0,1004424 E BIO3 GO:0006639 7,6,8 acylglycerol metabolism 4 0,0006 1 0,0057 0,1004424 E TGL4 GO:0006641 8,7,9 triacylglycerol metabolism 4 0,0006 1 0,0057 0,1004424 E TGL4 GO:0048518 3 positive regulation of biological process 78 0,0121 4 0,0227 0,1020516 E OAF1,UGA3,YRR1,INO4 GO:0030163 6,7 protein catabolism 145 0,0225 6 0,0341 0,1028984 E AMA1,GRR1,PRB1,VID30,UBX6,PAI3 GO:0009719 4 response to endogenous stimulus 183 0,0284 7 0,0398 0,1057231 E SNF3,PHR1,RAD1,MMS4,RGT2,YKU70,MEC1 GO:0042592 3 homeostasis 114 0,0177 5 0,0284 0,1091117 E OCT1,SMF3,RAV2,PPZ2,ISU1 GO:0006355 8 regulation of transcription, DNA-dependent 305 0,0473 10 0,0568 0,1101313 E MAL33,MAL13,POG1,CIN5,UGA3,YRR1,YKU70,PNC1,INO4,TRA1 GO:0031324 6 negative regulation of cellular metabolism 150 0,0232 6 0,0341 0,1103953 E VID30,GID8,FYV10,YKU70,PNC1,UBC8 GO:0006351 7 transcription, DNA-dependent 441 0,0683 13 0,0739 0,1111223 E MAL33,MAL13,POG1,CIN5,RSF1,MED4,UGA3,YRR1,NUT2,YKU70,PNC1,INO4,TRA1 GO:0009084 8,9 glutamine family amino acid biosynthesis 24 0,0037 2 0,0114 0,1117455 E PUT1,CIT2 GO:0019219 6 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 355 0,0550 11 0,0625 0,1139981 E MAL33,MAL13,OAF1,POG1,CIN5,UGA3,YRR1,YKU70,PNC1,INO4,TRA1 GO:0030005 7 di-, tri-valent inorganic cation homeostasis 52 0,0081 3 0,0170 0,1157534 E OCT1,SMF3,ISU1 GO:0009060 8 aerobic respiration 84 0,0130 4 0,0227 0,1171463 E MCT1,RSF1,COX14,SDH1 GO:0042775 8,10,7 ATP synthesis coupled electron transport (sensu Eukaryota) 25 0,0039 2 0,0114 0,1181757 E NDI1,SDH1 GO:0042773 7,9,6 ATP synthesis coupled electron transport 25 0,0039 2 0,0114 0,1181757 E NDI1,SDH1 GO:0006366 8 transcription from RNA polymerase II promoter 277 0,0429 9 0,0511 0,1194495 E POG1,CIN5,RSF1,MED4,UGA3,YRR1,NUT2,INO4,TRA1 GO:0009892 5 negative regulation of metabolism 157 0,0243 6 0,0341 0,1204031 E VID30,GID8,FYV10,YKU70,PNC1,UBC8 GO:0006508 7 proteolysis 157 0,0243 6 0,0341 0,1204031 E GRR1,VID30,UBX6,MDJ1,RIM11,RPN14 GO:0006089 7 lactate metabolism 5 0,0008 1 0,0057 0,1221465 E GLO4 GO:0009636 6 response to toxin 5 0,0008 1 0,0057 0,1221465 E GLO4 GO:0000076 8 DNA replication checkpoint 5 0,0008 1 0,0057 0,1221465 E MEC1 GO:0007130 10 synaptonemal complex formation 5 0,0008 1 0,0057 0,1221465 E CST9 GO:0046185 6 aldehyde catabolism 5 0,0008 1 0,0057 0,1221465 E GLO4 GO:0005979 11,9,8,10,7 regulation of glycogen biosynthesis 5 0,0008 1 0,0057 0,1221465 E PCL6 GO:0006627 11,9,10 mitochondrial protein processing 5 0,0008 1 0,0057 0,1221465 E OCT1 GO:0019323 8,9 pentose catabolism 5 0,0008 1 0,0057 0,1221465 E GRE3 GO:0045116 8 protein neddylation 5 0,0008 1 0,0057 0,1221465 E UBA3 GO:0007089 8,6 traversing start control point of mitotic cell cycle 5 0,0008 1 0,0057 0,1221465 E GID8 GO:0006470 8 protein amino acid dephosphorylation 26 0,0040 2 0,0114 0,1245587 E GIP2,LTP1 GO:0045333 7 cellular respiration 89 0,0138 4 0,0227 0,1292720 E MCT1,RSF1,COX14,SDH1 GO:0007186 6 G-protein coupled receptor protein signaling pathway 27 0,0042 2 0,0114 0,1308820 E CYR1,STE18 GO:0006575 6 amino acid derivative metabolism 27 0,0042 2 0,0114 0,1308820 E SRY1,FMS1 GO:0000279 5 M phase 257 0,0398 8 0,0455 0,1350457 E AMA1,REC114,CYR1,RCK2,MMS4,MEC1,MPS1,CST9 GO:0005984 7 disaccharide metabolism 28 0,0043 2 0,0114 0,1371339 E TPS3,TSL1 GO:0000726 8,7 non-recombinational repair 28 0,0043 2 0,0114 0,1371339 E RAD1,YKU70 GO:0019932 6 second-messenger-mediated signaling 28 0,0043 2 0,0114 0,1371339 E RSF1,CYR1 GO:0045893 9 positive regulation of transcription, DNA-dependent 59 0,0091 3 0,0170 0,1405478 E UGA3,YRR1,INO4 GO:0009113 8,7 purine base biosynthesis 6 0,0009 1 0,0057 0,1425983 E PHO2 GO:0016558 11,8,9,7,10 protein import into peroxisome matrix 6 0,0009 1 0,0057 0,1425983 E PEX25 GO:0006415 9,8 translational termination 6 0,0009 1 0,0057 0,1425983 E ECM32 GO:0019321 7,8 pentose metabolism 6 0,0009 1 0,0057 0,1425983 E GRE3 GO:0016237 5 microautophagy 6 0,0009 1 0,0057 0,1425983 E NVJ1 GO:0006445 9,8,7 regulation of translation 29 0,0045 2 0,0114 0,1433036 E ECM32,COX14 GO:0016192 5,6 vesicle-mediated transport 282 0,0437 8 0,0455 0,1439761 E GYP7,GEM1,KIN1,YPK1,PEP12,APM2,EMP46,GGA1 GO:0006357 9 regulation of transcription from RNA polymerase II promoter 181 0,0280 6 0,0341 0,1483020 E POG1,CIN5,UGA3,YRR1,INO4,TRA1 GO:0006417 8,7,6 regulation of protein biosynthesis 30 0,0046 2 0,0114 0,1493815 E ECM32,COX14 GO:0006807 4 nitrogen compound metabolism 236 0,0366 7 0,0398 0,1504346 E VID30,NPR1,UGA3,PUT1,CIT2,PHO2,FMS1 GO:0042493 6 response to drug 31 0,0048 2 0,0114 0,1553585 E CIN5,YRR1 GO:0044270 6,5 nitrogen compound catabolism 31 0,0048 2 0,0114 0,1553585 E PUT1,FMS1 GO:0009310 6,7 amine catabolism 31 0,0048 2 0,0114 0,1553585 E PUT1,FMS1 GO:0030004 7 monovalent inorganic cation homeostasis 32 0,0050 2 0,0114 0,1612265 E RAV2,PPZ2 GO:0006560 8,9 proline metabolism 7 0,0011 1 0,0057 0,1618495 E PUT1 GO:0001306 7,6 age-dependent response to oxidative stress 7 0,0011 1 0,0057 0,1618495 E CYR1 GO:0006595 7,8 polyamine metabolism 7 0,0011 1 0,0057 0,1618495 E FMS1 GO:0006083 7 acetate metabolism 7 0,0011 1 0,0057 0,1618495 E ACS1 GO:0001324 8,7 age-dependent response to oxidative stress during chronological cell aging 7 0,0011 1 0,0057 0,1618495 E CYR1 GO:0001323 7,6 age-dependent general metabolic decline during chronological cell aging 7 0,0011 1 0,0057 0,1618495 E CYR1 GO:0031146 12,13 SCF-dependent proteasomal ubiquitin-dependent protein catabolism 7 0,0011 1 0,0057 0,1618495 E GRR1 GO:0019722 7 calcium-mediated signaling 7 0,0011 1 0,0057 0,1618495 E RSF1 GO:0001302 6,5 replicative cell aging 33 0,0051 2 0,0114 0,1669780 E SIP2,PNC1 GO:0006512 8 ubiquitin cycle 69 0,0107 3 0,0170 0,1721518 E UBP15,GRR1,UBC8 GO:0019362 8,7 pyridine nucleotide metabolism 34 0,0053 2 0,0114 0,1726065 E SOL4,PNC1 GO:0046365 7,8 monosaccharide catabolism 34 0,0053 2 0,0114 0,1726065 E SOL4,GRE3 GO:0046483 5 heterocycle metabolism 71 0,0110 3 0,0170 0,1777556 E BIO3,PHO2,HEM15 GO:0016311 7 dephosphorylation 35 0,0054 2 0,0114 0,1781058 E GIP2,LTP1 GO:0006071 7 glycerol metabolism 8 0,0012 1 0,0057 0,1799500 E TCO89 GO:0006012 8,9 galactose metabolism 8 0,0012 1 0,0057 0,1799500 E GAL7 GO:0019935 7 cyclic-nucleotide-mediated signaling 8 0,0012 1 0,0057 0,1799500 E CYR1 GO:0019933 8 cAMP-mediated signaling 8 0,0012 1 0,0057 0,1799500 E CYR1 GO:0006855 6,7,8 multidrug transport 8 0,0012 1 0,0057 0,1799500 E YRR1 GO:0015939 8 pantothenate metabolism 8 0,0012 1 0,0057 0,1799500 E FMS1 GO:0007571 6,5 age-dependent general metabolic decline 8 0,0012 1 0,0057 0,1799500 E CYR1 GO:0015940 8,9 pantothenate biosynthesis 8 0,0012 1 0,0057 0,1799500 E FMS1 GO:0019751 6 polyol metabolism 8 0,0012 1 0,0057 0,1799500 E TCO89 GO:0006974 5 response to DNA damage stimulus 177 0,0274 5 0,0284 0,1799898 E PHR1,RAD1,MMS4,YKU70,MEC1 GO:0046164 6 alcohol catabolism 37 0,0057 2 0,0114 0,1886964 E SOL4,GRE3 GO:0016125 6,7,8 sterol metabolism 37 0,0057 2 0,0114 0,1886964 E DAP1,MCR1 GO:0007129 9 synapsis 9 0,0014 1 0,0057 0,1969477 E CST9 GO:0031163 6 metallo-sulfur cluster assembly 9 0,0014 1 0,0057 0,1969477 E ISU1 GO:0000737 7,8 DNA catabolism, endonucleolytic 9 0,0014 1 0,0057 0,1969477 E REC114 GO:0006098 10,11,12,8 pentose-phosphate shunt 9 0,0014 1 0,0057 0,1969477 E SOL4 GO:0006616 13,11,9,12,10 SRP-dependent cotranslational protein targeting to membrane, translocation 9 0,0014 1 0,0057 0,1969477 E SSA4 GO:0016226 7 iron-sulfur cluster assembly 9 0,0014 1 0,0057 0,1969477 E ISU1 GO:0042138 10,8,9 meiotic DNA double-strand break formation 9 0,0014 1 0,0057 0,1969477 E REC114 GO:0042244 5 spore wall assembly 39 0,0060 2 0,0114 0,1987139 E AMA1,DIT1 GO:0030476 7,6 spore wall assembly (sensu Fungi) 39 0,0060 2 0,0114 0,1987139 E AMA1,DIT1 GO:0006302 8,7 double-strand break repair 41 0,0064 2 0,0114 0,2081312 E RAD1,YKU70 GO:0051329 6 interphase of mitotic cell cycle 86 0,0133 3 0,0170 0,2106767 E GRR1,POG1,GID8 GO:0051325 5 interphase 86 0,0133 3 0,0170 0,2106767 E GRR1,POG1,GID8 GO:0030447 3 filamentous growth 87 0,0135 3 0,0170 0,2122730 E SIP2,TPK2,TPK1 GO:0006817 8,9 phosphate transport 10 0,0015 1 0,0057 0,2128889 E PIC2 GO:0009117 6 nucleotide metabolism 90 0,0139 3 0,0170 0,2166091 E SOL4,PNC1,APA2 GO:0006631 6,7 fatty acid metabolism 43 0,0067 2 0,0114 0,2169285 E MCT1,OAF1 GO:0009064 7,8 glutamine family amino acid metabolism 43 0,0067 2 0,0114 0,2169285 E PUT1,CIT2 GO:0017038 6,7 protein import 91 0,0141 3 0,0170 0,2179044 E HSP78,ASM4,PEX25 GO:0007005 6 mitochondrion organization and biogenesis 95 0,0147 3 0,0170 0,2223463 E HSP78,ARC35,CRD1 GO:0000723 8 telomere maintenance 45 0,0070 2 0,0114 0,2250930 E YKU70,MEC1 GO:0008202 6,7 steroid metabolism 45 0,0070 2 0,0114 0,2250930 E DAP1,MCR1 GO:0006733 7 oxidoreduction coenzyme metabolism 45 0,0070 2 0,0114 0,2250930 E SOL4,PNC1 GO:0008652 7,8 amino acid biosynthesis 99 0,0153 3 0,0170 0,2256324 E PUT1,CIT2,PHO2 GO:0045002 9,8 double-strand break repair via single-strand annealing 11 0,0017 1 0,0057 0,2278182 E RAD1 GO:0006308 6,7 DNA catabolism 11 0,0017 1 0,0057 0,2278182 E REC114 GO:0006119 6,8 oxidative phosphorylation 46 0,0071 2 0,0114 0,2289356 E NDI1,SDH1 GO:0000082 7 G1/S transition of mitotic cell cycle 46 0,0071 2 0,0114 0,2289356 E GRR1,POG1 GO:0043161 11,12 proteasomal ubiquitin-dependent protein catabolism 46 0,0071 2 0,0114 0,2289356 E GRR1,VID30 GO:0044271 6,5 nitrogen compound biosynthesis 108 0,0167 3 0,0170 0,2290519 E PUT1,CIT2,PHO2 GO:0009309 6,7 amine biosynthesis 108 0,0167 3 0,0170 0,2290519 E PUT1,CIT2,PHO2 GO:0000075 6 cell cycle checkpoint 47 0,0073 2 0,0114 0,2326179 E MEC1,MPS1 GO:0006626 10,8,9 protein targeting to mitochondrion 47 0,0073 2 0,0114 0,2326179 E HSP78,OCT1 GO:0007124 4 pseudohyphal growth 48 0,0074 2 0,0114 0,2361396 E TPK2,TPK1 GO:0045944 10 positive regulation of transcription from RNA polymerase II promoter 48 0,0074 2 0,0114 0,2361396 E YRR1,INO4 GO:0007103 9,6 spindle pole body duplication in nuclear envelope 12 0,0019 1 0,0057 0,2417785 E MPS1 GO:0000083 8,10 G1/S-specific transcription in mitotic cell cycle 12 0,0019 1 0,0057 0,2417785 E POG1 GO:0006740 11,10 NADPH regeneration 12 0,0019 1 0,0057 0,2417785 E SOL4 GO:0009651 6 response to salt stress 12 0,0019 1 0,0057 0,2417785 E CIN5 GO:0009894 5 regulation of catabolism 12 0,0019 1 0,0057 0,2417785 E PCL6 GO:0006892 9,7,6,8 post-Golgi transport 51 0,0079 2 0,0114 0,2457456 E PEP12,GGA1 GO:0016567 9 protein ubiquitination 51 0,0079 2 0,0114 0,2457456 E GRR1,UBC8 GO:0030474 8,5 spindle pole body duplication 13 0,0020 1 0,0057 0,2548114 E MPS1 GO:0009065 8,9 glutamine family amino acid catabolism 13 0,0020 1 0,0057 0,2548114 E PUT1 GO:0000077 8,7 DNA damage checkpoint 13 0,0020 1 0,0057 0,2548114 E MEC1 GO:0006739 10,9 NADP metabolism 13 0,0020 1 0,0057 0,2548114 E SOL4 GO:0015893 5,6,7 drug transport 13 0,0020 1 0,0057 0,2548114 E YRR1 GO:0007534 9,6 gene conversion at mating-type locus 13 0,0020 1 0,0057 0,2548114 E RAD1 GO:0000754 7,5 adaptation to pheromone during conjugation with cellular fusion 13 0,0020 1 0,0057 0,2548114 E POG1 GO:0031023 6 microtubule organizing center organization and biogenesis 13 0,0020 1 0,0057 0,2548114 E MPS1 GO:0051300 7 spindle pole body organization and biogenesis 13 0,0020 1 0,0057 0,2548114 E MPS1 GO:0046148 6 pigment biosynthesis 14 0,0022 1 0,0057 0,2669566 E HEM15 GO:0006779 7 porphyrin biosynthesis 14 0,0022 1 0,0057 0,2669566 E HEM15 GO:0006547 8,9 histidine metabolism 14 0,0022 1 0,0057 0,2669566 E PHO2 GO:0042770 6 DNA damage response, signal transduction 14 0,0022 1 0,0057 0,2669566 E MEC1 GO:0009075 7,8 histidine family amino acid metabolism 14 0,0022 1 0,0057 0,2669566 E PHO2 GO:0009076 8,9 histidine family amino acid biosynthesis 14 0,0022 1 0,0057 0,2669566 E PHO2 GO:0000183 13,8,11,6 chromatin silencing at rDNA 14 0,0022 1 0,0057 0,2669566 E PNC1 GO:0000105 9,10 histidine biosynthesis 14 0,0022 1 0,0057 0,2669566 E PHO2 GO:0006783 8,7 heme biosynthesis 14 0,0022 1 0,0057 0,2669566 E HEM15 GO:0051188 6 cofactor biosynthesis 71 0,0110 2 0,0114 0,2758277 E FMS1,HEM15 GO:0006778 6 porphyrin metabolism 15 0,0023 1 0,0057 0,2782525 E HEM15 GO:0007231 6 osmosensory signaling pathway 15 0,0023 1 0,0057 0,2782525 E RCK2 GO:0042168 7,6 heme metabolism 15 0,0023 1 0,0057 0,2782525 E HEM15 GO:0000245 8,10,12 spliceosome assembly 15 0,0023 1 0,0057 0,2782525 E RSE1 GO:0046356 8 acetyl-CoA catabolism 15 0,0023 1 0,0057 0,2782525 E SDH1 GO:0044272 6 sulfur compound biosynthesis 15 0,0023 1 0,0057 0,2782525 E BIO3 GO:0042440 5 pigment metabolism 15 0,0023 1 0,0057 0,2782525 E HEM15 GO:0006311 9,8 meiotic gene conversion 15 0,0023 1 0,0057 0,2782525 E REC114 GO:0006099 9,8 tricarboxylic acid cycle 15 0,0023 1 0,0057 0,2782525 E SDH1 GO:0015698 7,8 inorganic anion transport 16 0,0025 1 0,0057 0,2887361 E PIC2 GO:0006113 7 fermentation 16 0,0025 1 0,0057 0,2887361 E ACS1 GO:0006144 7 purine base metabolism 16 0,0025 1 0,0057 0,2887361 E PHO2 GO:0043094 5 metabolic compound salvage 16 0,0025 1 0,0057 0,2887361 E PNC1 GO:0006820 6,7 anion transport 17 0,0026 1 0,0057 0,2984431 E PIC2 GO:0009109 7 coenzyme catabolism 17 0,0026 1 0,0057 0,2984431 E SDH1 GO:0009408 6,5 response to heat 17 0,0026 1 0,0057 0,2984431 E LRE1 GO:0031570 7 DNA integrity checkpoint 17 0,0026 1 0,0057 0,2984431 E MEC1 GO:0007533 5 mating type switching 17 0,0026 1 0,0057 0,2984431 E RAD1 GO:0051187 6 cofactor catabolism 18 0,0028 1 0,0057 0,3074076 E SDH1 GO:0019748 4 secondary metabolism 18 0,0028 1 0,0057 0,3074076 E HEM15 GO:0016579 9 protein deubiquitination 18 0,0028 1 0,0057 0,3074076 E UBP15 GO:0000724 9,8 double-strand break repair via homologous recombination 18 0,0028 1 0,0057 0,3074076 E YKU70 GO:0000209 10 protein polyubiquitination 19 0,0029 1 0,0057 0,3156628 E UBC8 GO:0007006 6,7 mitochondrial membrane organization and biogenesis 19 0,0029 1 0,0057 0,3156628 E CRD1 GO:0000725 8,7 recombinational repair 19 0,0029 1 0,0057 0,3156628 E YKU70 GO:0006614 12,10,8,11,9 SRP-dependent cotranslational protein targeting to membrane 19 0,0029 1 0,0057 0,3156628 E SSA4 GO:0006100 8 tricarboxylic acid cycle intermediate metabolism 19 0,0029 1 0,0057 0,3156628 E CIT2 GO:0006303 9,8 double-strand break repair via nonhomologous end-joining 19 0,0029 1 0,0057 0,3156628 E YKU70 GO:0008213 8 protein amino acid alkylation 20 0,0031 1 0,0057 0,3232403 E PPM1 GO:0009266 5 response to temperature stimulus 20 0,0031 1 0,0057 0,3232403 E LRE1 GO:0006869 5,6 lipid transport 20 0,0031 1 0,0057 0,3232403 E PXA2 GO:0006479 9,8 protein amino acid methylation 20 0,0031 1 0,0057 0,3232403 E PPM1 GO:0040020 8 regulation of meiosis 20 0,0031 1 0,0057 0,3232403 E RCK2 GO:0031577 7 spindle checkpoint 21 0,0033 1 0,0057 0,3301709 E MPS1 GO:0007094 10,8 mitotic spindle checkpoint 21 0,0033 1 0,0057 0,3301709 E MPS1 GO:0030150 11,9,7,10,8 protein import into mitochondrial matrix 21 0,0033 1 0,0057 0,3301709 E HSP78 GO:0046112 7,6 nucleobase biosynthesis 21 0,0033 1 0,0057 0,3301709 E PHO2 GO:0000750 7,8,6 signal transduction during conjugation with cellular fusion 22 0,0034 1 0,0057 0,3364838 E STE18 GO:0006513 10 protein monoubiquitination 22 0,0034 1 0,0057 0,3364838 E UBC8 GO:0006613 11,9,7,10,8 cotranslational protein targeting to membrane 22 0,0034 1 0,0057 0,3364838 E SSA4 GO:0007093 9,7 mitotic checkpoint 22 0,0034 1 0,0057 0,3364838 E MPS1 GO:0030641 8 hydrogen ion homeostasis 23 0,0036 1 0,0057 0,3422074 E RAV2 GO:0000080 7 G1 phase of mitotic cell cycle 23 0,0036 1 0,0057 0,3422074 E GID8 GO:0045851 6 pH reduction 23 0,0036 1 0,0057 0,3422074 E RAV2 GO:0006608 11,9,8,10 snRNP protein import into nucleus 23 0,0036 1 0,0057 0,3422074 E ASM4 GO:0007531 4 mating type determination 23 0,0036 1 0,0057 0,3422074 E RAD1 GO:0051030 8,7,9 snRNA transport 23 0,0036 1 0,0057 0,3422074 E ASM4 GO:0006610 11,9,8,10 ribosomal protein import into nucleus 23 0,0036 1 0,0057 0,3422074 E ASM4 GO:0051453 9,6 regulation of cellular pH 23 0,0036 1 0,0057 0,3422074 E RAV2 GO:0007530 3 sex determination 23 0,0036 1 0,0057 0,3422074 E RAD1 GO:0051318 6 G1 phase 23 0,0036 1 0,0057 0,3422074 E GID8 GO:0051452 10,7 cellular pH reduction 23 0,0036 1 0,0057 0,3422074 E RAV2 GO:0006408 11,9,10,8 snRNA export from nucleus 23 0,0036 1 0,0057 0,3422074 E ASM4 GO:0007035 11,9,7,8 vacuolar acidification 23 0,0036 1 0,0057 0,3422074 E RAV2 GO:0006607 11,9,8,10 NLS-bearing substrate import into nucleus 23 0,0036 1 0,0057 0,3422074 E ASM4 GO:0000001 8,7 mitochondrion inheritance 25 0,0039 1 0,0057 0,3519947 E ARC35 GO:0008204 7,8,9 ergosterol metabolism 25 0,0039 1 0,0057 0,3519947 E MCR1 GO:0006576 6,7 biogenic amine metabolism 25 0,0039 1 0,0057 0,3519947 E FMS1 GO:0048311 7,6 mitochondrion distribution 25 0,0039 1 0,0057 0,3519947 E ARC35 GO:0006609 11,9,8,10 mRNA-binding (hnRNP) protein import into nucleus 25 0,0039 1 0,0057 0,3519947 E ASM4 GO:0051646 6,5 mitochondrion localization 25 0,0039 1 0,0057 0,3519947 E ARC35 GO:0006696 8,9,10 ergosterol biosynthesis 25 0,0039 1 0,0057 0,3519947 E MCR1 GO:0006312 8 mitotic recombination 26 0,0040 1 0,0057 0,3561098 E RAD1 GO:0006407 11,9,10,8 rRNA export from nucleus 26 0,0040 1 0,0057 0,3561098 E ASM4 GO:0051029 8,7,9 rRNA transport 26 0,0040 1 0,0057 0,3561098 E ASM4 GO:0006885 5 regulation of pH 27 0,0042 1 0,0057 0,3597385 E RAV2 GO:0000002 7 mitochondrial genome maintenance 27 0,0042 1 0,0057 0,3597385 E HSP78 GO:0006999 7 nuclear pore organization and biogenesis 27 0,0042 1 0,0057 0,3597385 E ASM4 GO:0045047 10,8,6,9,7 protein targeting to ER 28 0,0043 1 0,0057 0,3629041 E SSA4 GO:0016573 12,9 histone acetylation 28 0,0043 1 0,0057 0,3629041 E TRA1 GO:0009063 7,8 amino acid catabolism 28 0,0043 1 0,0057 0,3629041 E PUT1 GO:0016126 7,8,9 sterol biosynthesis 29 0,0045 1 0,0057 0,3656290 E MCR1 GO:0006007 9,10 glucose catabolism 29 0,0045 1 0,0057 0,3656290 E SOL4 GO:0019320 8,9 hexose catabolism 29 0,0045 1 0,0057 0,3656290 E SOL4 GO:0006665 7,8 sphingolipid metabolism 29 0,0045 1 0,0057 0,3656290 E YPK1 GO:0015672 7,8 monovalent inorganic cation transport 30 0,0046 1 0,0057 0,3679347 E ENA2 GO:0006612 10,8,9 protein targeting to membrane 31 0,0048 1 0,0057 0,3698420 E SSA4 GO:0051235 4 maintenance of localization 31 0,0048 1 0,0057 0,3698420 E SMF3 GO:0006769 9,8 nicotinamide metabolism 31 0,0048 1 0,0057 0,3698420 E SOL4 GO:0006289 8,7 nucleotide-excision repair 31 0,0048 1 0,0057 0,3698420 E RAD1 GO:0016044 5 membrane organization and biogenesis 32 0,0050 1 0,0057 0,3713706 E CRD1 GO:0016485 8 protein processing 32 0,0050 1 0,0057 0,3713706 E OCT1 GO:0007020 9 microtubule nucleation 33 0,0051 1 0,0057 0,3725398 E NUD1 GO:0009112 6 nucleobase metabolism 33 0,0051 1 0,0057 0,3725398 E PHO2 GO:0043414 7 biopolymer methylation 35 0,0054 1 0,0057 0,3738725 E PPM1 GO:0042157 7 lipoprotein metabolism 36 0,0056 1 0,0057 0,3740706 E SHR5 GO:0006400 8 tRNA modification 36 0,0056 1 0,0057 0,3740706 E TAD3 GO:0006887 6,7 exocytosis 36 0,0056 1 0,0057 0,3740706 E KIN1 GO:0006694 7,6,8 steroid biosynthesis 36 0,0056 1 0,0057 0,3740706 E MCR1 GO:0042158 8,7 lipoprotein biosynthesis 36 0,0056 1 0,0057 0,3740706 E SHR5 GO:0006497 9,8 protein lipidation 36 0,0056 1 0,0057 0,3740706 E SHR5 GO:0008150 1 biological_process 6454 1,0000 176 1,0000 1,0000000 D ASR1,HXT7,DAP1,GIP2,UBP15,CBS2,MAL33,GYP7,MEF2,LDB17,GEM1,ADR1,MTL1,SRY1,SIP2,PPM1,PXA2,PHM8,MAL13,SNF3,AMA1,MCT1,OAF1,GRR1,FRT2,POG1,PNS1,TPK2,NDI1,TPS3,KRE29,HSP78,PRB1,REC114,PEX5,PHR1,CIN5,RSF1,SSA4,LEE1,AST2,HOR7,SHR5,COS111,RAD1,CYR1,SOL4,FAR10,HAP5,SYN8,FMP16,VID30,YPT35,FMP29,OCT1,OMS1,NPR1,MED4,SET6,GSY2,GID8,UBX6,BIO3,UGA3,ENA2,GAL7,TPK1,KIN1,PEX2,GRE2,UIP4,TCO89,MDJ1,MTQ1,FYV10,SWI1,ASM4,ECM32,GRE3,PUT1,ARC35,TSL1,GLC3,NUD1,RCK2,HXT6,HXT16,YRR1,PEX25,PEX22,COX14,LRE1,CIT2,CTT1,YPK1,SNX41,ACS1,NCE103,NVJ1,MMS4,NUT2,PEP12,SPG4,APM2,PHO2,STB3,SSE2,TAD3,RGT2,FMS1,HEM15,YKU70,SDH1,RSE1,VPS30,THI21,MEC1,STE18,KIN82,YPK2,ZTA1,ZSP1,ECM21,ATG7,GLG1,MPM1,HXT5,GTO3,PNC1,UBA3,EMI2,PAI3,UBP11,EMP46,OPY2,INO4,SCP1,MCR1,LTP1,SPG3,GLO4,ATG12,MPS1,SGA1,MRP8,MRL1,SMF3,DIT1,THI3,ATG19,PIC2,IRA2,FMP12,XBP1,UIP3,TGL4,CRD1,RIM11,GGA1,UBC8,CST9,HSP104,PAU7,EHT1,HSP26,RPN14,PCL6,ASK10,RAV2,HAP2,UGX2,PPZ2,TRA1,ISU1,APA2,PDX1 GO:0030471 4 spindle pole body and microtubule cycle (sensu Fungi) 37 0,0057 1 0,0057 0,3739783 D MPS1 GO:0006473 8 protein amino acid acetylation 38 0,0059 1 0,0057 0,3736113 D TRA1 GO:0048308 6 organelle inheritance 38 0,0059 1 0,0057 0,3736113 D ARC35 GO:0006752 7 group transfer coenzyme metabolism 44 0,0068 1 0,0057 0,3664372 D FMS1 GO:0031509 12 telomeric heterochromatin formation 45 0,0070 1 0,0057 0,3645338 D PNC1 GO:0006611 10,8,9 protein export from nucleus 45 0,0070 1 0,0057 0,3645338 D ASM4 GO:0006348 13,8,11,6 chromatin silencing at telomere 45 0,0070 1 0,0057 0,3645338 D PNC1 GO:0006606 10,8,7,9 protein import into nucleus 46 0,0071 1 0,0057 0,3624596 D ASM4 GO:0051170 9,7,8 nuclear import 46 0,0071 1 0,0057 0,3624596 D ASM4 GO:0007088 8,6 regulation of mitosis 48 0,0074 1 0,0057 0,3578412 D MPS1 GO:0006997 6 nuclear organization and biogenesis 49 0,0076 1 0,0057 0,3553171 D ASM4 GO:0051640 4 organelle localization 49 0,0076 1 0,0057 0,3553171 D ARC35 GO:0008654 8,7,9 phospholipid biosynthesis 52 0,0081 1 0,0057 0,3469959 D INO4 GO:0006725 5 aromatic compound metabolism 57 0,0088 1 0,0057 0,3311256 D PHO2 GO:0006790 5 sulfur metabolism 57 0,0088 1 0,0057 0,3311256 D BIO3 GO:0009108 7 coenzyme biosynthesis 57 0,0088 1 0,0057 0,3311256 D FMS1 GO:0030001 7,8 metal ion transport 57 0,0088 1 0,0057 0,3311256 D ENA2 GO:0016570 11,8 histone modification 59 0,0091 1 0,0057 0,3242465 D TRA1 GO:0006970 5 response to osmotic stress 59 0,0091 1 0,0057 0,3242465 D CIN5 GO:0016569 10 covalent chromatin modification 59 0,0091 1 0,0057 0,3242465 D TRA1 GO:0006406 11,9,10,8 mRNA export from nucleus 62 0,0096 1 0,0057 0,3135153 D ASM4 GO:0051028 8,7,9 mRNA transport 62 0,0096 1 0,0057 0,3135153 D ASM4 GO:0007015 9 actin filament organization 63 0,0098 1 0,0057 0,3098502 D SCP1 GO:0006897 6,7 endocytosis 69 0,0107 1 0,0057 0,2872663 D YPK1 GO:0046467 7,6,8 membrane lipid biosynthesis 71 0,0110 1 0,0057 0,2796105 D INO4 GO:0050658 7,6,8 RNA transport 72 0,0112 1 0,0057 0,2757747 D ASM4 GO:0051236 5 establishment of RNA localization 72 0,0112 1 0,0057 0,2757747 D ASM4 GO:0006405 10,8,9,7 RNA export from nucleus 72 0,0112 1 0,0057 0,2757747 D ASM4 GO:0050657 6,7 nucleic acid transport 72 0,0112 1 0,0057 0,2757747 D ASM4 GO:0031507 11 heterochromatin formation 79 0,0122 2 0,0114 0,2741096 D YKU70,PNC1 GO:0045814 4 negative regulation of gene expression, epigenetic 79 0,0122 2 0,0114 0,2741096 D YKU70,PNC1 GO:0006342 12,7,10,5 chromatin silencing 79 0,0122 2 0,0114 0,2741096 D YKU70,PNC1 GO:0016458 6 gene silencing 79 0,0122 2 0,0114 0,2741096 D YKU70,PNC1 GO:0040029 3 regulation of gene expression, epigenetic 84 0,0130 2 0,0114 0,2700527 D YKU70,PNC1 GO:0031497 10 chromatin assembly 84 0,0130 2 0,0114 0,2700527 D YKU70,PNC1 GO:0000226 8 microtubule cytoskeleton organization and biogenesis 85 0,0132 2 0,0114 0,2690056 D ARC35,NUD1 GO:0006888 9,7,6,8 ER to Golgi transport 76 0,0118 1 0,0057 0,2604497 D EMP46 GO:0006644 7,8 phospholipid metabolism 79 0,0122 1 0,0057 0,2490482 D INO4 GO:0030036 8 actin cytoskeleton organization and biogenesis 100 0,0155 2 0,0114 0,2460639 D ARC35,SCP1 GO:0007017 7 microtubule-based process 100 0,0155 2 0,0114 0,2460639 D ARC35,NUD1 GO:0006333 9 chromatin assembly or disassembly 100 0,0155 2 0,0114 0,2460639 D YKU70,PNC1 GO:0015931 5,6 nucleobase, nucleoside, nucleotide and nucleic acid transport 80 0,0124 1 0,0057 0,2452775 D ASM4 GO:0030029 7 actin filament-based process 104 0,0161 2 0,0114 0,2382521 D ARC35,SCP1 GO:0006643 6,7 membrane lipid metabolism 106 0,0164 2 0,0114 0,2341674 D YPK1,INO4 GO:0006403 4 RNA localization 83 0,0129 1 0,0057 0,2340824 D ASM4 GO:0006811 5,6 ion transport 107 0,0166 2 0,0114 0,2320869 D ENA2,PIC2 GO:0040007 2 growth 113 0,0175 3 0,0170 0,2287715 D SIP2,TPK2,TPK1 GO:0006511 10,11 ubiquitin-dependent protein catabolism 121 0,0187 3 0,0170 0,2254940 D GRR1,VID30,UBX6 GO:0019941 9,10 modification-dependent protein catabolism 121 0,0187 3 0,0170 0,2254940 D GRR1,VID30,UBX6 GO:0044257 7,8 cellular protein catabolism 123 0,0191 3 0,0170 0,2241880 D GRR1,VID30,UBX6 GO:0051603 8,9 proteolysis during cellular protein catabolism 123 0,0191 3 0,0170 0,2241880 D GRR1,VID30,UBX6 GO:0008610 6,5,7 lipid biosynthesis 124 0,0192 3 0,0170 0,2234683 D INO4,MCR1,CRD1 GO:0051168 9,7,8 nuclear export 86 0,0133 1 0,0057 0,2230975 D ASM4 GO:0006338 10 chromatin remodeling 132 0,0205 3 0,0170 0,2162656 D SWI1,YKU70,PNC1 GO:0006812 6,7 cation transport 89 0,0138 1 0,0057 0,2123609 D ENA2 GO:0045229 5 external encapsulating structure organization and biogenesis 141 0,0218 3 0,0170 0,2056086 D MTL1,LRE1,ECM21 GO:0048193 8,6,7 Golgi vesicle transport 141 0,0218 3 0,0170 0,2056086 D PEP12,EMP46,GGA1 GO:0007047 6 cell wall organization and biogenesis 141 0,0218 3 0,0170 0,2056086 D MTL1,LRE1,ECM21 GO:0006281 7,6 DNA repair 150 0,0232 4 0,0227 0,2000982 D PHR1,RAD1,MMS4,YKU70 GO:0045892 9 negative regulation of transcription, DNA-dependent 124 0,0192 2 0,0114 0,1944452 D YKU70,PNC1 GO:0016481 8 negative regulation of transcription 128 0,0198 2 0,0114 0,1853754 D YKU70,PNC1 GO:0000398 9,11 nuclear mRNA splicing, via spliceosome 97 0,0150 1 0,0057 0,1851570 D RSE1 GO:0000377 10 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 98 0,0152 1 0,0057 0,1819162 D RSE1 GO:0016568 9 chromatin modification 181 0,0280 4 0,0227 0,1808312 D SWI1,YKU70,PNC1,TRA1 GO:0006310 7 DNA recombination 189 0,0293 5 0,0284 0,1799710 D REC114,RAD1,MMS4,YKU70,MEC1 GO:0006519 5 amino acid and derivative metabolism 197 0,0305 5 0,0284 0,1778152 D SRY1,PUT1,CIT2,PHO2,FMS1 GO:0045045 5,6 secretory pathway 202 0,0313 5 0,0284 0,1756945 D SSA4,KIN1,PEP12,EMP46,GGA1 GO:0046903 5 secretion 209 0,0324 5 0,0284 0,1718362 D SSA4,KIN1,PEP12,EMP46,GGA1 GO:0051169 8,6,7 nuclear transport 103 0,0160 1 0,0057 0,1662790 D ASM4 GO:0006399 7 tRNA metabolism 103 0,0160 1 0,0057 0,1662790 D TAD3 GO:0045934 7 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 138 0,0214 2 0,0114 0,1630880 D YKU70,PNC1 GO:0000375 9 RNA splicing, via transesterification reactions 105 0,0163 1 0,0057 0,1602942 D RSE1 GO:0044265 6 cellular macromolecule catabolism 258 0,0400 7 0,0398 0,1541442 D GRR1,SOL4,VID30,UBX6,GRE3,SGA1,PCL6 GO:0006323 7 DNA packaging 205 0,0318 4 0,0227 0,1530941 D SWI1,YKU70,PNC1,TRA1 GO:0006325 8 establishment and/or maintenance of chromatin architecture 205 0,0318 4 0,0227 0,1530941 D SWI1,YKU70,PNC1,TRA1 GO:0006913 8,6,7 nucleocytoplasmic transport 109 0,0169 1 0,0057 0,1487951 D ASM4 GO:0007001 7 chromosome organization and biogenesis (sensu Eukaryota) 243 0,0377 5 0,0284 0,1426589 D SWI1,YKU70,MEC1,PNC1,TRA1 GO:0006461 7 protein complex assembly 148 0,0229 2 0,0114 0,1419027 D RSE1,RAV2 GO:0006520 6,7 amino acid metabolism 182 0,0282 3 0,0170 0,1416907 D PUT1,CIT2,PHO2 GO:0009308 5 amine metabolism 218 0,0338 4 0,0227 0,1363971 D PUT1,CIT2,PHO2,FMS1 GO:0051276 6 chromosome organization and biogenesis 255 0,0395 5 0,0284 0,1300750 D SWI1,YKU70,MEC1,PNC1,TRA1 GO:0000278 5 mitotic cell cycle 231 0,0358 4 0,0227 0,1196858 D GRR1,POG1,GID8,MPS1 GO:0008380 8 RNA splicing 126 0,0195 1 0,0057 0,1068509 D RSE1 GO:0009451 7 RNA modification 126 0,0195 1 0,0057 0,1068509 D TAD3 GO:0006397 8 mRNA processing 132 0,0205 1 0,0057 0,0945965 D RSE1 GO:0044260 5 cellular macromolecule metabolism 1448 0,2244 39 0,2216 0,0729465 D GIP2,UBP15,CBS2,MEF2,SIP2,PPM1,GRR1,TPK2,HSP78,SSA4,SHR5,VID30,OCT1,GSY2,UBX6,TPK1,MDJ1,ECM32,GLC3,RCK2,COX14,YPK1,SSE2,RSE1,KIN82,YPK2,GLG1,UBA3,LTP1,SGA1,MRP8,RIM11,UBC8,HSP104,HSP26,RPN14,PCL6,RAV2,TRA1 GO:0007067 7 mitosis 146 0,0226 1 0,0057 0,0705989 D MPS1 GO:0019538 5 protein metabolism 1424 0,2206 37 0,2102 0,0704334 D GIP2,UBP15,CBS2,MEF2,SIP2,PPM1,AMA1,GRR1,TPK2,HSP78,PRB1,SSA4,SHR5,VID30,OCT1,UBX6,TPK1,MDJ1,ECM32,RCK2,COX14,YPK1,SSE2,RSE1,KIN82,YPK2,UBA3,PAI3,LTP1,MRP8,RIM11,UBC8,HSP104,HSP26,RPN14,RAV2,TRA1 GO:0000087 6 M phase of mitotic cell cycle 148 0,0229 1 0,0057 0,0676499 D MPS1 GO:0043170 4 macromolecule metabolism 2511 0,3891 66 0,3750 0,0582941 D GIP2,UBP15,CBS2,MAL33,MEF2,ADR1,SIP2,PPM1,MAL13,AMA1,GRR1,TPK2,TPS3,HSP78,PRB1,REC114,PHR1,SSA4,SHR5,RAD1,SOL4,HAP5,VID30,OCT1,GSY2,GID8,UBX6,GAL7,TPK1,MDJ1,FYV10,SWI1,ECM32,GRE3,TSL1,GLC3,RCK2,COX14,CIT2,YPK1,MMS4,SSE2,TAD3,YKU70,SDH1,RSE1,MEC1,KIN82,YPK2,GLG1,PNC1,UBA3,PAI3,LTP1,GLO4,SGA1,MRP8,RIM11,UBC8,HSP104,HSP26,RPN14,PCL6,RAV2,HAP2,TRA1 GO:0044267 6 cellular protein metabolism 1400 0,2169 34 0,1932 0,0565329 D GIP2,UBP15,CBS2,MEF2,SIP2,PPM1,GRR1,TPK2,HSP78,SSA4,SHR5,VID30,OCT1,UBX6,TPK1,MDJ1,ECM32,RCK2,COX14,YPK1,SSE2,RSE1,KIN82,YPK2,UBA3,LTP1,MRP8,RIM11,UBC8,HSP104,HSP26,RPN14,RAV2,TRA1 GO:0009058 4 biosynthesis 1184 0,1835 27 0,1534 0,0476247 D CBS2,MEF2,TPS3,SHR5,VID30,GSY2,GID8,BIO3,FYV10,ECM32,PUT1,TSL1,GLC3,COX14,CIT2,PHO2,FMS1,HEM15,THI21,GLG1,INO4,MCR1,MRP8,THI3,CRD1,UBC8,PCL6 GO:0043283 5 biopolymer metabolism 1593 0,2468 38 0,2159 0,0457500 D GIP2,UBP15,SIP2,PPM1,AMA1,GRR1,TPK2,PRB1,REC114,PHR1,SHR5,RAD1,VID30,OCT1,GSY2,UBX6,TPK1,SWI1,GLC3,RCK2,YPK1,MMS4,TAD3,YKU70,RSE1,MEC1,KIN82,YPK2,GLG1,PNC1,UBA3,PAI3,LTP1,SGA1,RIM11,UBC8,PCL6,TRA1 GO:0044249 5 cellular biosynthesis 1105 0,1712 24 0,1364 0,0389165 D CBS2,MEF2,TPS3,SHR5,VID30,GSY2,GID8,BIO3,FYV10,ECM32,PUT1,TSL1,GLC3,COX14,CIT2,PHO2,FMS1,HEM15,THI21,GLG1,MRP8,THI3,UBC8,PCL6 GO:0016071 7 mRNA metabolism 185 0,0287 1 0,0057 0,0297595 D RSE1 GO:0007010 6 cytoskeleton organization and biogenesis 290 0,0449 3 0,0170 0,0273908 D ARC35,NUD1,SCP1 GO:0006259 6 DNA metabolism 555 0,0860 9 0,0511 0,0272621 D REC114,PHR1,RAD1,SWI1,MMS4,YKU70,MEC1,PNC1,TRA1 GO:0009059 6,5 macromolecule biosynthesis 844 0,1308 16 0,0909 0,0261523 D CBS2,MEF2,TPS3,SHR5,VID30,GSY2,GID8,FYV10,ECM32,TSL1,GLC3,COX14,GLG1,MRP8,UBC8,PCL6 GO:0016043 4 cell organization and biogenesis 1473 0,2282 32 0,1818 0,0245577 D ADR1,MTL1,OAF1,HSP78,PEX5,SSA4,OCT1,PEX2,SWI1,ASM4,ARC35,NUD1,PEX25,PEX22,LRE1,PEP12,YKU70,VPS30,MEC1,ECM21,ATG7,PNC1,EMP46,SCP1,ATG12,MPS1,MRL1,ATG19,CRD1,GGA1,RAV2,TRA1 GO:0006996 5 organelle organization and biogenesis 1017 0,1576 18 0,1023 0,0097833 D ADR1,OAF1,HSP78,PEX5,PEX2,SWI1,ASM4,ARC35,NUD1,PEX25,PEX22,YKU70,MEC1,PNC1,SCP1,MPS1,CRD1,TRA1 GO:0006139 5 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1500 0,2324 29 0,1648 0,0066864 D MAL33,ADR1,MAL13,OAF1,POG1,REC114,PHR1,CIN5,RSF1,RAD1,SOL4,HAP5,MED4,UGA3,SWI1,YRR1,MMS4,NUT2,PHO2,TAD3,YKU70,RSE1,MEC1,PNC1,INO4,ASK10,HAP2,TRA1,APA2 GO:0043037 8,7 translation 415 0,0643 3 0,0170 0,0022106 D MEF2,ECM32,COX14 GO:0006414 9,8 translational elongation 312 0,0483 1 0,0057 0,0013271 D MEF2 GO:0006396 7 RNA processing 346 0,0536 1 0,0057 0,0005493 D RSE1 GO:0000004 2 biological process unknown 1639 0,2540 25 0,1420 0,0001024 D LDB17,PHM8,PNS1,KRE29,LEE1,AST2,FMP16,YPT35,FMP29,OMS1,SET6,UIP4,MTQ1,SPG4,STB3,ZTA1,ZSP1,MPM1,GTO3,UBP11,SPG3,FMP12,UIP3,PAU7,UGX2 GO:0006412 7,6 protein biosynthesis 783 0,1213 6 0,0341 2,879985E-05 D CBS2,MEF2,SHR5,ECM32,COX14,MRP8 GO:0016070 6 RNA metabolism 539 0,0835 2 0,0114 2,343538E-05 D TAD3,RSE1