GO_ID LEVEL(S) TERM NB_IN_REF FREQ_IN_REF NB_IN_SET FREQ_IN_SET P_VALUE ENRICHMENT/DEPLETION GENES_IN_SET GO:0000004 2 biological process unknown 1639 0,254 9 0,0466 7,44E-15 D FMP32,LOT6,FYV4,FMP38,UIP5,PFA5,KIN4,YPS7,PHS1 GO:0007582 2 physiological process 4771 0,7392 183 0,9482 1,13E-14 E RRN3,TYR1,RDI1,PNP1,COG2,POL2,TOS2,KTR7,KAR4,YCS4,ARO7,VAC17,CKA2,SRP68,RGR1,FKH2,CDC11,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,NAT2,ARV1,BUD21,NAR1,TUP1,VPS75,STT3,TIM50,PGD1,DCG1,GIN4,DST1,TRS20,PDS5,SRL1,HMT1,RRP7,HSL7,SKI8,NOG1,HSH155,BBP1,YIP1,RSM24,ERG12,HIS7,PML39,COG1,CSM1,RPB2,MNN11,MSH1,SLN1,BUD16,TAO3,TAF6,SEY1,AAD3,TRK1,ERG6,CAF4,GON7,CCT8,DBP7,PEX15,POL30,HOT1,VPS53,SRP54,ALG14,MXR1,TUB4,POM34,THG1,MRS11,SPL2,SRP21,IBD2,WSC2,RFC2,SNF12,PPS1,TLG2,SIT4,AKL1,MNN9,MCD4,MET7,NGL2,ERG26,SMD1,CSM3,SCH9,GAB1,PRP19,SAN1,ARO3,HEM1,SUB2,VBA1,EXG1,PDS1,BNI5,MET30,PMT1,ILV6,ATX2,NDC1,YSH1,HUT1,IKI1,SLY1,CLB5,SPC25,OPY1,TBF1,KAE1,WTM2,IFH1,CKS1,PEX31,TRM11,ACS2,YEH2,BFR1,CDC47,NUP100,DIB1,NMT1,UBC1,PUS1,CBK1,TRP5,ECM31,NAM7,RRP42,MID1,QDR3,CDC50,BAP3,BUD6,PUF4,RRP43,HSL1,AGE2,NUP133,FRE1,NUP145,GCD14,FKH1,YPT31,RSR1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,ARL3,MSI1,GNA1,PCL2,UTP22,TFB4,GRX4,LIP5,DDP1,KTR6,CCA1,CCZ1,OAZ1,MEI4,CCT7,CTF18,MUD2,HUR1,ERP1,DPH1 GO:0009987 2 cellular process 4682 0,7254 181 0,9378 2,19E-14 E RRN3,TYR1,RDI1,PNP1,COG2,POL2,TOS2,KTR7,KAR4,YCS4,ARO7,VAC17,CKA2,SRP68,RGR1,FKH2,CDC11,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,NAT2,ARV1,BUD21,NAR1,TUP1,VPS75,STT3,TIM50,PGD1,GIN4,DST1,TRS20,PDS5,SRL1,HMT1,RRP7,HSL7,SKI8,NOG1,HSH155,BBP1,YIP1,RSM24,ERG12,HIS7,PML39,COG1,CSM1,RPB2,MNN11,MSH1,KSS1,SLN1,BUD16,TAO3,TAF6,SEY1,AAD3,TRK1,ERG6,CAF4,GON7,CCT8,DBP7,PEX15,POL30,HOT1,VPS53,SRP54,ALG14,MXR1,TUB4,POM34,THG1,MRS11,SRP21,IBD2,WSC2,RFC2,SNF12,PPS1,TLG2,SIT4,AKL1,MNN9,MCD4,MET7,NGL2,ERG26,SMD1,CSM3,SCH9,GAB1,PRP19,SAN1,ARO3,HEM1,SUB2,VBA1,EXG1,PDS1,BNI5,MET30,PMT1,ILV6,ATX2,NDC1,YSH1,HUT1,IKI1,SLY1,CLB5,SPC25,OPY1,TBF1,KAE1,WTM2,IFH1,CKS1,PEX31,TRM11,ACS2,YEH2,BFR1,CDC47,NUP100,DIB1,NMT1,UBC1,PUS1,CBK1,TRP5,ECM31,NAM7,RRP42,MID1,QDR3,CDC50,BAP3,BUD6,PUF4,RRP43,HSL1,AGE2,NUP133,FRE1,NUP145,GCD14,FKH1,YPT31,RSR1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,ARL3,MSI1,GNA1,PCL2,UTP22,TFB4,GRX4,LIP5,DDP1,KTR6,CCA1,CCZ1,MEI4,CCT7,CTF18,MUD2,HUR1,ERP1,DPH1 GO:0050875 3 cellular physiological process 4641 0,7191 180 0,9326 3,19E-14 E RRN3,TYR1,RDI1,PNP1,COG2,POL2,TOS2,KTR7,KAR4,YCS4,ARO7,VAC17,CKA2,SRP68,RGR1,FKH2,CDC11,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,NAT2,ARV1,BUD21,NAR1,TUP1,VPS75,STT3,TIM50,PGD1,GIN4,DST1,TRS20,PDS5,SRL1,HMT1,RRP7,HSL7,SKI8,NOG1,HSH155,BBP1,YIP1,RSM24,ERG12,HIS7,PML39,COG1,CSM1,RPB2,MNN11,MSH1,SLN1,BUD16,TAO3,TAF6,SEY1,AAD3,TRK1,ERG6,CAF4,GON7,CCT8,DBP7,PEX15,POL30,HOT1,VPS53,SRP54,ALG14,MXR1,TUB4,POM34,THG1,MRS11,SRP21,IBD2,WSC2,RFC2,SNF12,PPS1,TLG2,SIT4,AKL1,MNN9,MCD4,MET7,NGL2,ERG26,SMD1,CSM3,SCH9,GAB1,PRP19,SAN1,ARO3,HEM1,SUB2,VBA1,EXG1,PDS1,BNI5,MET30,PMT1,ILV6,ATX2,NDC1,YSH1,HUT1,IKI1,SLY1,CLB5,SPC25,OPY1,TBF1,KAE1,WTM2,IFH1,CKS1,PEX31,TRM11,ACS2,YEH2,BFR1,CDC47,NUP100,DIB1,NMT1,UBC1,PUS1,CBK1,TRP5,ECM31,NAM7,RRP42,MID1,QDR3,CDC50,BAP3,BUD6,PUF4,RRP43,HSL1,AGE2,NUP133,FRE1,NUP145,GCD14,FKH1,YPT31,RSR1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,ARL3,MSI1,GNA1,PCL2,UTP22,TFB4,GRX4,LIP5,DDP1,KTR6,CCA1,CCZ1,MEI4,CCT7,CTF18,MUD2,HUR1,ERP1,DPH1 GO:0016043 4 cell organization and biogenesis 1473 0,2282 76 0,3938 6,95E-08 E RDI1,COG2,POL2,KTR7,KAR4,YCS4,VAC17,CKA2,SRP68,CDC11,HCM1,BUD21,TUP1,VPS75,TIM50,GIN4,TRS20,PDS5,HMT1,RRP7,NOG1,BBP1,YIP1,PML39,COG1,BUD16,TAO3,TAF6,SEY1,GON7,CCT8,DBP7,PEX15,VPS53,SRP54,TUB4,POM34,MRS11,SRP21,WSC2,SNF12,SIT4,AKL1,NGL2,SCH9,SAN1,SUB2,EXG1,PDS1,NDC1,SLY1,SPC25,TBF1,IFH1,PEX31,YEH2,NUP100,CBK1,RRP42,CDC50,BUD6,PUF4,RRP43,AGE2,NUP133,NUP145,FKH1,RSR1,LSM5,ARL3,MSI1,UTP22,KTR6,CCZ1,CCT7,ERP1 GO:0007049 4 cell cycle 397 0,0615 32 0,1658 1,30E-07 E KAR4,YCS4,CKA2,FKH2,HCM1,GIN4,DST1,PDS5,HSL7,SKI8,CSM1,TAF6,TUB4,IBD2,RFC2,PPS1,SIT4,CSM3,PDS1,MET30,CLB5,WTM2,CKS1,BFR1,CBK1,CDC50,HSL1,FKH1,PCL2,TFB4,MEI4,CTF18 GO:0006139 5 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1500 0,2324 74 0,3834 7,04E-07 E RRN3,PNP1,POL2,KAR4,YCS4,CKA2,RGR1,FKH2,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,BUD21,TUP1,PGD1,DST1,SRL1,RRP7,SKI8,HSH155,HIS7,CSM1,RPB2,MSH1,TAF6,CAF4,DBP7,POL30,HOT1,THG1,RFC2,SNF12,SIT4,NGL2,SMD1,PRP19,SAN1,SUB2,PDS1,YSH1,IKI1,CLB5,TBF1,IFH1,CKS1,TRM11,BFR1,CDC47,DIB1,PUS1,NAM7,RRP42,CDC50,PUF4,RRP43,NUP133,NUP145,GCD14,FKH1,MGS1,LEU3,LSM5,FIP1,MSI1,GNA1,UTP22,TFB4,DDP1,CCA1,MEI4,MUD2,HUR1 GO:0043283 5 biopolymer metabolism 1593 0,2468 77 0,399 8,41E-07 E POL2,KTR7,YCS4,CKA2,NAT5,RNH201,RFA2,SMX3,NAT2,BUD21,TUP1,STT3,GIN4,DST1,HMT1,RRP7,SKI8,HSH155,CSM1,MNN11,MSH1,SLN1,TAF6,DBP7,POL30,ALG14,THG1,RFC2,SNF12,PPS1,SIT4,MNN9,MCD4,NGL2,SMD1,SCH9,GAB1,PRP19,SAN1,SUB2,EXG1,PDS1,MET30,PMT1,YSH1,CLB5,TBF1,IFH1,TRM11,BFR1,CDC47,DIB1,NMT1,UBC1,PUS1,NAM7,RRP42,PUF4,RRP43,HSL1,NUP133,NUP145,GCD14,FKH1,MGS1,LSM5,PTP3,FIP1,MSI1,UTP22,KTR6,CCA1,OAZ1,MEI4,MUD2,HUR1,DPH1 GO:0000278 5 mitotic cell cycle 231 0,0358 21 0,1088 3,32E-06 E KAR4,YCS4,CKA2,FKH2,HCM1,PDS5,HSL7,TAF6,TUB4,IBD2,PPS1,SIT4,CSM3,PDS1,CLB5,BFR1,CBK1,CDC50,HSL1,TFB4,CTF18 GO:0051244 4 regulation of cellular physiological process 566 0,0877 36 0,1865 5,49E-06 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,GIN4,HSL7,TAF6,CAF4,HOT1,IBD2,RFC2,PPS1,AKL1,CSM3,SUB2,IKI1,CLB5,TBF1,IFH1,CKS1,BFR1,CBK1,NAM7,CDC50,PUF4,HSL1,FKH1,MGS1,LEU3,MSI1,TFB4 GO:0050794 3 regulation of cellular process 568 0,088 36 0,1865 5,93E-06 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,GIN4,HSL7,TAF6,CAF4,HOT1,IBD2,RFC2,PPS1,AKL1,CSM3,SUB2,IKI1,CLB5,TBF1,IFH1,CKS1,BFR1,CBK1,NAM7,CDC50,PUF4,HSL1,FKH1,MGS1,LEU3,MSI1,TFB4 GO:0050789 2 regulation of biological process 597 0,0925 37 0,1917 7,17E-06 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,GIN4,HSL7,TAF6,CAF4,HOT1,IBD2,RFC2,PPS1,AKL1,CSM3,SUB2,IKI1,CLB5,TBF1,IFH1,CKS1,BFR1,CBK1,NAM7,CDC50,PUF4,HSL1,FKH1,MGS1,LEU3,PTP3,MSI1,TFB4 GO:0050791 3 regulation of physiological process 584 0,0905 36 0,1865 1,08E-05 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,GIN4,HSL7,TAF6,CAF4,HOT1,IBD2,RFC2,PPS1,AKL1,CSM3,SUB2,IKI1,CLB5,TBF1,IFH1,CKS1,BFR1,CBK1,NAM7,CDC50,PUF4,HSL1,FKH1,MGS1,LEU3,MSI1,TFB4 GO:0016071 7 mRNA metabolism 185 0,0287 17 0,0881 2,47E-05 E SMX3,DST1,SKI8,HSH155,SMD1,PRP19,SUB2,YSH1,BFR1,DIB1,NAM7,RRP42,PUF4,RRP43,LSM5,FIP1,MUD2 GO:0006996 5 organelle organization and biogenesis 1017 0,1576 51 0,2642 4,08E-05 E RDI1,POL2,KAR4,YCS4,VAC17,CKA2,CDC11,HCM1,BUD21,TUP1,GIN4,PDS5,RRP7,NOG1,BBP1,BUD16,TAF6,CCT8,DBP7,PEX15,VPS53,TUB4,MRS11,WSC2,SNF12,SIT4,AKL1,NGL2,SAN1,SUB2,NDC1,SPC25,TBF1,IFH1,PEX31,NUP100,CBK1,RRP42,CDC50,BUD6,PUF4,RRP43,NUP133,NUP145,FKH1,RSR1,LSM5,MSI1,UTP22,CCZ1,CCT7 GO:0045449 7 regulation of transcription 324 0,0502 22 0,114 0,0001532 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,CDC50,PUF4,FKH1,LEU3,MSI1,TFB4 GO:0000074 5 regulation of progression through cell cycle 140 0,0217 13 0,0674 0,0001937 E FKH2,GIN4,HSL7,IBD2,RFC2,PPS1,CSM3,CLB5,CKS1,BFR1,CBK1,HSL1,FKH1 GO:0043037 8,7 translation 415 0,0643 2 0,0104 0,0002045 D NAM7,DED1 GO:0019219 6 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 355 0,055 23 0,1192 0,0002115 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,CDC50,PUF4,FKH1,MGS1,LEU3,MSI1,TFB4 GO:0009101 8,7 glycoprotein biosynthesis 72 0,0112 9 0,0466 0,0002165 E KTR7,STT3,MNN11,GON7,ALG14,MNN9,PMT1,YEH2,KTR6 GO:0008152 3 metabolism 3427 0,531 125 0,6477 0,000239 E RRN3,TYR1,PNP1,POL2,KTR7,KAR4,YCS4,ARO7,CKA2,RGR1,FKH2,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,NAT2,ARV1,BUD21,NAR1,TUP1,STT3,PGD1,DCG1,GIN4,DST1,SRL1,HMT1,RRP7,SKI8,HSH155,RSM24,ERG12,HIS7,CSM1,RPB2,MNN11,MSH1,SLN1,TAF6,AAD3,ERG6,CAF4,GON7,CCT8,DBP7,POL30,HOT1,ALG14,MXR1,THG1,RFC2,SNF12,PPS1,SIT4,MNN9,MCD4,MET7,NGL2,ERG26,SMD1,SCH9,GAB1,PRP19,SAN1,ARO3,HEM1,SUB2,EXG1,PDS1,MET30,PMT1,ILV6,YSH1,IKI1,CLB5,TBF1,KAE1,IFH1,CKS1,TRM11,ACS2,YEH2,BFR1,CDC47,DIB1,NMT1,UBC1,PUS1,TRP5,ECM31,NAM7,RRP42,CDC50,PUF4,RRP43,HSL1,NUP133,NUP145,GCD14,FKH1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,MSI1,GNA1,UTP22,TFB4,GRX4,LIP5,DDP1,KTR6,CCA1,OAZ1,MEI4,CCT7,MUD2,HUR1,DPH1 GO:0009100 7 glycoprotein metabolism 73 0,0113 9 0,0466 0,0002398 E KTR7,STT3,MNN11,GON7,ALG14,MNN9,PMT1,YEH2,KTR6 GO:0006350 6 transcription 484 0,075 28 0,1451 0,0002831 E RRN3,POL2,KAR4,YCS4,CKA2,RGR1,FKH2,SPT21,ELP4,HCM1,TUP1,PGD1,DST1,RPB2,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,CKS1,CDC50,PUF4,FKH1,LEU3,MSI1,TFB4 GO:0044237 4 cellular metabolism 3376 0,5231 123 0,6373 0,000307 E RRN3,TYR1,PNP1,POL2,KTR7,KAR4,YCS4,ARO7,CKA2,RGR1,FKH2,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,NAT2,ARV1,BUD21,NAR1,TUP1,STT3,PGD1,GIN4,DST1,SRL1,HMT1,RRP7,SKI8,HSH155,RSM24,ERG12,HIS7,CSM1,RPB2,MNN11,MSH1,SLN1,TAF6,AAD3,ERG6,CAF4,GON7,CCT8,DBP7,POL30,HOT1,ALG14,MXR1,THG1,RFC2,SNF12,PPS1,SIT4,MNN9,MCD4,MET7,NGL2,ERG26,SMD1,SCH9,GAB1,PRP19,SAN1,ARO3,HEM1,SUB2,EXG1,PDS1,MET30,PMT1,ILV6,YSH1,IKI1,CLB5,TBF1,KAE1,IFH1,CKS1,TRM11,ACS2,YEH2,BFR1,CDC47,DIB1,NMT1,UBC1,PUS1,TRP5,ECM31,NAM7,RRP42,CDC50,PUF4,RRP43,HSL1,NUP133,NUP145,GCD14,FKH1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,MSI1,GNA1,UTP22,TFB4,GRX4,LIP5,DDP1,KTR6,CCA1,MEI4,CCT7,MUD2,HUR1,DPH1 GO:0006355 8 regulation of transcription, DNA-dependent 305 0,0473 20 0,1036 0,0004535 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,PUF4,FKH1,LEU3,MSI1,TFB4 GO:0031323 5 regulation of cellular metabolism 403 0,0624 24 0,1244 0,0005004 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,NAM7,CDC50,PUF4,FKH1,MGS1,LEU3,MSI1,TFB4 GO:0006464 7 protein modification 431 0,0668 25 0,1295 0,0005576 E KTR7,CKA2,NAT5,NAT2,STT3,GIN4,HMT1,MNN11,SLN1,TAF6,ALG14,PPS1,SIT4,MNN9,MCD4,SCH9,GAB1,MET30,PMT1,NMT1,UBC1,HSL1,PTP3,KTR6,DPH1 GO:0044238 4 primary metabolism 3152 0,4884 115 0,5959 0,0005856 E RRN3,TYR1,PNP1,POL2,KTR7,KAR4,YCS4,ARO7,CKA2,RGR1,FKH2,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,NAT2,ARV1,BUD21,TUP1,STT3,PGD1,GIN4,DST1,SRL1,HMT1,RRP7,SKI8,HSH155,RSM24,ERG12,HIS7,CSM1,RPB2,MNN11,MSH1,SLN1,TAF6,ERG6,CAF4,GON7,CCT8,DBP7,POL30,HOT1,ALG14,THG1,RFC2,SNF12,PPS1,SIT4,MNN9,MCD4,NGL2,ERG26,SMD1,SCH9,GAB1,PRP19,SAN1,ARO3,SUB2,EXG1,PDS1,MET30,PMT1,ILV6,YSH1,IKI1,CLB5,TBF1,KAE1,IFH1,CKS1,TRM11,YEH2,BFR1,CDC47,DIB1,NMT1,UBC1,PUS1,TRP5,NAM7,RRP42,CDC50,PUF4,RRP43,HSL1,NUP133,NUP145,GCD14,FKH1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,MSI1,GNA1,UTP22,TFB4,DDP1,KTR6,CCA1,OAZ1,MEI4,CCT7,MUD2,HUR1,DPH1 GO:0007010 6 cytoskeleton organization and biogenesis 290 0,0449 19 0,0984 0,0006231 E RDI1,CKA2,CDC11,HCM1,GIN4,BBP1,BUD16,CCT8,TUB4,WSC2,SIT4,AKL1,NDC1,SPC25,CBK1,CDC50,BUD6,RSR1,CCT7 GO:0016070 6 RNA metabolism 539 0,0835 29 0,1503 0,0006727 E SMX3,BUD21,DST1,RRP7,SKI8,HSH155,DBP7,THG1,NGL2,SMD1,PRP19,SUB2,YSH1,IFH1,TRM11,BFR1,DIB1,PUS1,NAM7,RRP42,PUF4,RRP43,NUP145,GCD14,LSM5,FIP1,UTP22,CCA1,MUD2 GO:0046907 7,5,6 intracellular transport 488 0,0756 27 0,1399 0,0006808 E COG2,SRP68,VPS75,TIM50,TRS20,HMT1,NOG1,YIP1,PML39,COG1,PEX15,VPS53,SRP54,POM34,MRS11,SRP21,SUB2,PDS1,NDC1,SLY1,NUP100,AGE2,NUP133,NUP145,ARL3,CCZ1,ERP1 GO:0043412 6 biopolymer modification 567 0,0879 30 0,1554 0,0007088 E KTR7,CKA2,NAT5,NAT2,STT3,GIN4,HMT1,MNN11,SLN1,TAF6,ALG14,THG1,PPS1,SIT4,MNN9,MCD4,SCH9,GAB1,MET30,PMT1,TRM11,NMT1,UBC1,PUS1,HSL1,GCD14,PTP3,KTR6,CCA1,DPH1 GO:0006260 7 DNA replication 103 0,016 10 0,0518 0,0007211 E POL2,RNH201,RFA2,CSM1,POL30,RFC2,CLB5,CDC47,MGS1,HUR1 GO:0006351 7 transcription, DNA-dependent 441 0,0683 25 0,1295 0,0007578 E RRN3,POL2,KAR4,YCS4,CKA2,RGR1,FKH2,SPT21,ELP4,HCM1,PGD1,DST1,RPB2,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,PUF4,FKH1,LEU3,MSI1,TFB4 GO:0051329 6 interphase of mitotic cell cycle 86 0,0133 9 0,0466 0,0007761 E CKA2,FKH2,HCM1,HSL7,TAF6,SIT4,CLB5,CDC50,HSL1 GO:0051325 5 interphase 86 0,0133 9 0,0466 0,0007761 E CKA2,FKH2,HCM1,HSL7,TAF6,SIT4,CLB5,CDC50,HSL1 GO:0006617 13,11,9,12,10 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 7 0,0011 3 0,0155 0,000818 E SRP68,SRP54,SRP21 GO:0051649 6,5 establishment of cellular localization 498 0,0772 27 0,1399 0,000901 E COG2,SRP68,VPS75,TIM50,TRS20,HMT1,NOG1,YIP1,PML39,COG1,PEX15,VPS53,SRP54,POM34,MRS11,SRP21,SUB2,PDS1,NDC1,SLY1,NUP100,AGE2,NUP133,NUP145,ARL3,CCZ1,ERP1 GO:0006913 8,6,7 nucleocytoplasmic transport 109 0,0169 10 0,0518 0,0010934 E HMT1,NOG1,PML39,POM34,SUB2,PDS1,NDC1,NUP100,NUP133,NUP145 GO:0019222 4 regulation of metabolism 429 0,0665 24 0,1244 0,00112 E POL2,KAR4,YCS4,CKA2,FKH2,SPT21,ELP4,HCM1,TUP1,TAF6,CAF4,HOT1,SUB2,IKI1,TBF1,IFH1,NAM7,CDC50,PUF4,FKH1,MGS1,LEU3,MSI1,TFB4 GO:0018193 8 peptidyl-amino acid modification 17 0,0026 4 0,0207 0,0012538 E NAT2,HMT1,NMT1,DPH1 GO:0006397 8 mRNA processing 132 0,0205 11 0,057 0,0013479 E SMX3,DST1,HSH155,SMD1,PRP19,SUB2,YSH1,DIB1,LSM5,FIP1,MUD2 GO:0051641 5,4 cellular localization 521 0,0807 27 0,1399 0,0016417 E COG2,SRP68,VPS75,TIM50,TRS20,HMT1,NOG1,YIP1,PML39,COG1,PEX15,VPS53,SRP54,POM34,MRS11,SRP21,SUB2,PDS1,NDC1,SLY1,NUP100,AGE2,NUP133,NUP145,ARL3,CCZ1,ERP1 GO:0006396 7 RNA processing 346 0,0536 20 0,1036 0,0018865 E SMX3,BUD21,DST1,RRP7,HSH155,DBP7,NGL2,SMD1,PRP19,SUB2,YSH1,IFH1,DIB1,RRP42,RRP43,NUP145,LSM5,FIP1,UTP22,MUD2 GO:0015931 5,6 nucleobase, nucleoside, nucleotide and nucleic acid transport 80 0,0124 8 0,0415 0,0019517 E HMT1,PML39,MCD4,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0006259 6 DNA metabolism 555 0,086 28 0,1451 0,001959 E POL2,YCS4,RNH201,RFA2,TUP1,DST1,SKI8,CSM1,MSH1,TAF6,POL30,RFC2,SNF12,SIT4,SAN1,SUB2,PDS1,CLB5,TBF1,IFH1,CDC47,PUF4,NUP133,FKH1,MGS1,MSI1,MEI4,HUR1 GO:0007275 2 development 373 0,0578 21 0,1088 0,0019983 E POL2,YCS4,CKA2,CDC11,GIN4,BUD16,TAO3,SIT4,SCH9,SUB2,TBF1,IFH1,UBC1,CBK1,CDC50,BUD6,PUF4,FKH1,RSR1,MSI1,MEI4 GO:0000279 5 M phase 257 0,0398 16 0,0829 0,0025065 E KAR4,YCS4,DST1,PDS5,SKI8,CSM1,TUB4,IBD2,CSM3,PDS1,WTM2,BFR1,CBK1,TFB4,MEI4,CTF18 GO:0051169 8,6,7 nuclear transport 103 0,016 9 0,0466 0,0025715 E HMT1,NOG1,PML39,SUB2,PDS1,NDC1,NUP100,NUP133,NUP145 GO:0000348 9,11,13 nuclear mRNA branch site recognition 3 0,0005 2 0,0104 0,0025902 E SUB2,MUD2 GO:0000370 10,11,12,13,14 U2-type nuclear mRNA branch site recognition 3 0,0005 2 0,0104 0,0025902 E SUB2,MUD2 GO:0040029 3 regulation of gene expression, epigenetic 84 0,013 8 0,0415 0,0026089 E POL2,YCS4,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0009072 7,6,8 aromatic amino acid family metabolism 21 0,0033 4 0,0207 0,0027986 E TYR1,ARO7,ARO3,TRP5 GO:0007067 7 mitosis 146 0,0226 11 0,057 0,0028296 E KAR4,YCS4,PDS5,TUB4,IBD2,CSM3,PDS1,BFR1,CBK1,TFB4,CTF18 GO:0006486 9,8 protein amino acid glycosylation 67 0,0104 7 0,0363 0,0028619 E KTR7,STT3,MNN11,ALG14,MNN9,PMT1,KTR6 GO:0043413 7 biopolymer glycosylation 67 0,0104 7 0,0363 0,0028619 E KTR7,STT3,MNN11,ALG14,MNN9,PMT1,KTR6 GO:0051168 9,7,8 nuclear export 86 0,0133 8 0,0415 0,0029935 E HMT1,NOG1,PML39,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0006886 8,6,7 intracellular protein transport 239 0,037 15 0,0777 0,0030837 E SRP68,VPS75,TIM50,NOG1,PEX15,SRP54,MRS11,SRP21,PDS1,NDC1,NUP100,NUP133,NUP145,ARL3,CCZ1 GO:0000087 6 M phase of mitotic cell cycle 148 0,0229 11 0,057 0,0031161 E KAR4,YCS4,PDS5,TUB4,IBD2,CSM3,PDS1,BFR1,CBK1,TFB4,CTF18 GO:0006400 8 tRNA modification 36 0,0056 5 0,0259 0,0034176 E THG1,TRM11,PUS1,GCD14,CCA1 GO:0006605 9,7,8 protein targeting 221 0,0342 14 0,0725 0,0037928 E SRP68,VPS75,TIM50,NOG1,PEX15,SRP54,MRS11,SRP21,PDS1,NDC1,NUP100,NUP133,NUP145,CCZ1 GO:0015031 5,6 protein transport 245 0,038 15 0,0777 0,0037994 E SRP68,VPS75,TIM50,NOG1,PEX15,SRP54,MRS11,SRP21,PDS1,NDC1,NUP100,NUP133,NUP145,ARL3,CCZ1 GO:0016125 6,7,8 sterol metabolism 37 0,0057 5 0,0259 0,0038358 E ARV1,ERG12,ERG6,ERG26,YEH2 GO:0006405 10,8,9,7 RNA export from nucleus 72 0,0112 7 0,0363 0,0041817 E HMT1,PML39,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0050657 6,7 nucleic acid transport 72 0,0112 7 0,0363 0,0041817 E HMT1,PML39,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0050658 7,6,8 RNA transport 72 0,0112 7 0,0363 0,0041817 E HMT1,PML39,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0051236 5 establishment of RNA localization 72 0,0112 7 0,0363 0,0041817 E HMT1,PML39,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0006402 8 mRNA catabolism 55 0,0085 6 0,0311 0,0045173 E SKI8,NAM7,RRP42,PUF4,RRP43,LSM5 GO:0000301 10,8,7,9 retrograde transport, vesicle recycling within Golgi 4 0,0006 2 0,0104 0,0050271 E COG2,COG1 GO:0000135 7 septin checkpoint 4 0,0006 2 0,0104 0,0050271 E GIN4,HSL1 GO:0000086 7 G2/M transition of mitotic cell cycle 25 0,0039 4 0,0207 0,00525 E CKA2,HSL7,CLB5,HSL1 GO:0045184 5 establishment of protein localization 255 0,0395 15 0,0777 0,0052663 E SRP68,VPS75,TIM50,NOG1,PEX15,SRP54,MRS11,SRP21,PDS1,NDC1,NUP100,NUP133,NUP145,ARL3,CCZ1 GO:0006810 4,5 transport 924 0,1432 39 0,2021 0,0056544 E COG2,SRP68,ARV1,VPS75,TIM50,TRS20,HMT1,NOG1,YIP1,PML39,COG1,PEX15,VPS53,SRP54,POM34,MRS11,SRP21,TLG2,AKL1,MCD4,SUB2,VBA1,PDS1,NDC1,HUT1,SLY1,NUP100,UBC1,MID1,QDR3,BAP3,AGE2,NUP133,FRE1,NUP145,YPT31,ARL3,CCZ1,ERP1 GO:0000398 9,11 nuclear mRNA splicing, via spliceosome 97 0,015 8 0,0415 0,0058937 E SMX3,HSH155,SMD1,PRP19,SUB2,DIB1,LSM5,MUD2 GO:0008104 4 protein localization 285 0,0442 16 0,0829 0,0060982 E SRP68,VPS75,TIM50,NOG1,PEX15,SRP54,MRS11,SRP21,PDS1,NDC1,NUP100,PUF4,NUP133,NUP145,ARL3,CCZ1 GO:0000377 10 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 98 0,0152 8 0,0415 0,0062308 E SMX3,HSH155,SMD1,PRP19,SUB2,DIB1,LSM5,MUD2 GO:0006272 10 leading strand elongation 14 0,0022 3 0,0155 0,0068989 E POL2,POL30,RFC2 GO:0000902 5,4 cellular morphogenesis 144 0,0223 10 0,0518 0,0070472 E CKA2,CDC11,GIN4,BUD16,TAO3,SCH9,CBK1,CDC50,BUD6,RSR1 GO:0009653 3 morphogenesis 144 0,0223 10 0,0518 0,0070472 E CKA2,CDC11,GIN4,BUD16,TAO3,SCH9,CBK1,CDC50,BUD6,RSR1 GO:0006091 5 generation of precursor metabolites and energy 224 0,0347 1 0,0052 0,0070528 D RSM24 GO:0051234 4 establishment of localization 942 0,146 39 0,2021 0,0073262 E COG2,SRP68,ARV1,VPS75,TIM50,TRS20,HMT1,NOG1,YIP1,PML39,COG1,PEX15,VPS53,SRP54,POM34,MRS11,SRP21,TLG2,AKL1,MCD4,SUB2,VBA1,PDS1,NDC1,HUT1,SLY1,NUP100,UBC1,MID1,QDR3,BAP3,AGE2,NUP133,FRE1,NUP145,YPT31,ARL3,CCZ1,ERP1 GO:0006487 10,9 protein amino acid N-linked glycosylation 44 0,0068 5 0,0259 0,0077601 E KTR7,STT3,ALG14,MNN9,KTR6 GO:0007062 5 sister chromatid cohesion 28 0,0043 4 0,0207 0,0077698 E PDS5,RFC2,CSM3,CTF18 GO:0006406 11,9,10,8 mRNA export from nucleus 62 0,0096 6 0,0311 0,0077826 E HMT1,PML39,SUB2,NUP100,NUP133,NUP145 GO:0051028 8,7,9 mRNA transport 62 0,0096 6 0,0311 0,0077826 E HMT1,PML39,SUB2,NUP100,NUP133,NUP145 GO:0031106 6 septin ring organization 5 0,0008 2 0,0104 0,0081304 E GIN4,BNI5 GO:0000921 7 septin ring assembly 5 0,0008 2 0,0104 0,0081304 E GIN4,BNI5 GO:0006379 9 mRNA cleavage 15 0,0023 3 0,0155 0,0083692 E DST1,YSH1,FIP1 GO:0000245 8,10,12 spliceosome assembly 15 0,0023 3 0,0155 0,0083692 E HSH155,SUB2,MUD2 GO:0008202 6,7 steroid metabolism 45 0,007 5 0,0259 0,008474 E ARV1,ERG12,ERG6,ERG26,YEH2 GO:0006403 4 RNA localization 83 0,0129 7 0,0363 0,0085105 E HMT1,PML39,SUB2,NDC1,NUP100,NUP133,NUP145 GO:0007059 4 chromosome segregation 104 0,0161 8 0,0415 0,0085415 E YCS4,PDS5,CSM1,RFC2,CSM3,PDS1,SPC25,CTF18 GO:0008380 8 RNA splicing 126 0,0195 9 0,0466 0,00857 E SMX3,HSH155,SMD1,PRP19,SUB2,DIB1,NUP145,LSM5,MUD2 GO:0006401 7 RNA catabolism 64 0,0099 6 0,0311 0,0089444 E SKI8,NAM7,RRP42,PUF4,RRP43,LSM5 GO:0000375 9 RNA splicing, via transesterification reactions 105 0,0163 8 0,0415 0,0089766 E SMX3,HSH155,SMD1,PRP19,SUB2,DIB1,LSM5,MUD2 GO:0031497 10 chromatin assembly 84 0,013 7 0,0363 0,0090131 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1 GO:0006606 10,8,7,9 protein import into nucleus 46 0,0071 5 0,0259 0,0092286 E PDS1,NDC1,NUP100,NUP133,NUP145 GO:0051170 9,7,8 nuclear import 46 0,0071 5 0,0259 0,0092286 E PDS1,NDC1,NUP100,NUP133,NUP145 GO:0051179 3 localization 991 0,1535 40 0,2073 0,0094282 E COG2,SRP68,ARV1,VPS75,TIM50,TRS20,HMT1,NOG1,YIP1,PML39,COG1,PEX15,VPS53,SRP54,POM34,MRS11,SRP21,TLG2,AKL1,MCD4,SUB2,VBA1,PDS1,NDC1,HUT1,SLY1,NUP100,UBC1,MID1,QDR3,BAP3,PUF4,AGE2,NUP133,FRE1,NUP145,YPT31,ARL3,CCZ1,ERP1 GO:0006271 9 DNA strand elongation 30 0,0046 4 0,0207 0,0097968 E POL2,RFA2,POL30,RFC2 GO:0007163 6,7,5 establishment and/or maintenance of cell polarity 107 0,0166 8 0,0415 0,0098913 E CKA2,CDC11,GIN4,BUD16,CBK1,CDC50,BUD6,RSR1 GO:0030467 7,8,6 establishment and/or maintenance of cell polarity (sensu Fungi) 107 0,0166 8 0,0415 0,0098913 E CKA2,CDC11,GIN4,BUD16,CBK1,CDC50,BUD6,RSR1 GO:0009073 8,7,9 aromatic amino acid family biosynthesis 16 0,0025 3 0,0155 0,0099966 E ARO7,ARO3,TRP5 GO:0000075 6 cell cycle checkpoint 47 0,0073 5 0,0259 0,0100242 E GIN4,IBD2,RFC2,CSM3,HSL1 GO:0045045 5,6 secretory pathway 202 0,0313 12 0,0622 0,0103157 E COG2,SRP68,TRS20,YIP1,COG1,VPS53,SRP54,SRP21,SLY1,AGE2,YPT31,ERP1 GO:0009059 6,5 macromolecule biosynthesis 844 0,1308 16 0,0829 0,0109702 D KTR7,STT3,RSM24,MNN11,GON7,ALG14,MNN9,MCD4,GAB1,PMT1,YEH2,NMT1,NAM7,DED1,GNA1,KTR6 GO:0006338 10 chromatin remodeling 132 0,0205 9 0,0466 0,0110609 E POL2,YCS4,SNF12,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0006325 8 establishment and/or maintenance of chromatin architecture 205 0,0318 12 0,0622 0,0113293 E POL2,YCS4,TUP1,TAF6,SNF12,SAN1,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0006323 7 DNA packaging 205 0,0318 12 0,0622 0,0113293 E POL2,YCS4,TUP1,TAF6,SNF12,SAN1,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0019438 6 aromatic compound biosynthesis 17 0,0026 3 0,0155 0,0117805 E ARO7,ARO3,TRP5 GO:0006950 4 response to stress 395 0,0612 19 0,0984 0,0125305 E POL2,CKA2,RFA2,SKI8,MSH1,SLN1,GON7,POL30,HOT1,MXR1,WSC2,RFC2,SIT4,SCH9,SAN1,PDS1,BUD6,MSI1,GRX4 GO:0046903 5 secretion 209 0,0324 12 0,0622 0,0127826 E COG2,SRP68,TRS20,YIP1,COG1,VPS53,SRP54,SRP21,SLY1,AGE2,YPT31,ERP1 GO:0017038 6,7 protein import 91 0,0141 7 0,0363 0,0130879 E TIM50,MRS11,PDS1,NDC1,NUP100,NUP133,NUP145 GO:0007020 9 microtubule nucleation 33 0,0051 4 0,0207 0,0133745 E BBP1,TUB4,NDC1,SPC25 GO:0006412 7,6 protein biosynthesis 783 0,1213 15 0,0777 0,0146844 D KTR7,STT3,RSM24,MNN11,GON7,ALG14,MNN9,MCD4,GAB1,PMT1,YEH2,NMT1,NAM7,DED1,KTR6 GO:0050896 3 response to stimulus 549 0,0851 24 0,1244 0,0153227 E POL2,CKA2,RFA2,SKI8,MSH1,SLN1,GON7,POL30,HOT1,MXR1,SPL2,WSC2,RFC2,SIT4,SCH9,SAN1,PDS1,MET30,CBK1,QDR3,BUD6,PTP3,MSI1,GRX4 GO:0015980 6 energy derivation by oxidation of organic compounds 194 0,0301 1 0,0052 0,015586 D RSM24 GO:0006614 12,10,8,11,9 SRP-dependent cotranslational protein targeting to membrane 19 0,0029 3 0,0155 0,0158107 E SRP68,SRP54,SRP21 GO:0007064 9,6,7 mitotic sister chromatid cohesion 19 0,0029 3 0,0155 0,0158107 E PDS5,CSM3,CTF18 GO:0007264 6 small GTPase mediated signal transduction 55 0,0085 5 0,0259 0,0179117 E RDI1,WSC2,BUD6,RSR1,MSI1 GO:0000819 5 sister chromatid segregation 55 0,0085 5 0,0259 0,0179117 E YCS4,PDS5,CSM3,PDS1,CTF18 GO:0000070 8,6 mitotic sister chromatid segregation 55 0,0085 5 0,0259 0,0179117 E YCS4,PDS5,CSM3,PDS1,CTF18 GO:0045005 9 maintenance of fidelity during DNA-dependent DNA replication 20 0,0031 3 0,0155 0,0180516 E POL2,POL30,RFC2 GO:0006298 8,10,7 mismatch repair 20 0,0031 3 0,0155 0,0180516 E POL2,POL30,RFC2 GO:0006273 10 lagging strand elongation 20 0,0031 3 0,0155 0,0180516 E POL2,RFA2,POL30 GO:0006888 9,7,6,8 ER to Golgi transport 76 0,0118 6 0,0311 0,0182559 E COG2,TRS20,YIP1,SLY1,AGE2,ERP1 GO:0006366 8 transcription from RNA polymerase II promoter 277 0,0429 14 0,0725 0,0189609 E KAR4,RGR1,FKH2,SPT21,ELP4,HCM1,PGD1,DST1,RPB2,TAF6,HOT1,IKI1,LEU3,TFB4 GO:0019954 3 asexual reproduction 77 0,0119 6 0,0311 0,0192181 E TOS2,CDC11,GIN4,TAO3,BUD6,RSR1 GO:0007114 5,4 cell budding 77 0,0119 6 0,0311 0,0192181 E TOS2,CDC11,GIN4,TAO3,BUD6,RSR1 GO:0051301 4 cell division 123 0,0191 8 0,0415 0,0194576 E TOS2,CDC11,GIN4,BUD16,TAO3,BNI5,BUD6,RSR1 GO:0043170 4 macromolecule metabolism 2511 0,3891 85 0,4404 0,0197573 E POL2,KTR7,YCS4,CKA2,NAT5,RNH201,RFA2,SMX3,NAT2,BUD21,TUP1,STT3,GIN4,DST1,HMT1,RRP7,SKI8,HSH155,RSM24,CSM1,MNN11,MSH1,SLN1,TAF6,GON7,CCT8,DBP7,POL30,ALG14,THG1,RFC2,SNF12,PPS1,SIT4,MNN9,MCD4,NGL2,SMD1,SCH9,GAB1,PRP19,SAN1,SUB2,EXG1,PDS1,MET30,PMT1,YSH1,CLB5,TBF1,KAE1,IFH1,TRM11,YEH2,BFR1,CDC47,DIB1,NMT1,UBC1,PUS1,NAM7,RRP42,PUF4,RRP43,HSL1,NUP133,NUP145,GCD14,FKH1,MGS1,LSM5,PTP3,DED1,FIP1,MSI1,GNA1,UTP22,KTR6,CCA1,OAZ1,MEI4,CCT7,MUD2,HUR1,DPH1 GO:0006333 9 chromatin assembly or disassembly 100 0,0155 7 0,0363 0,0198152 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1 GO:0006891 9,7,6,8 intra-Golgi transport 21 0,0033 3 0,0155 0,0204383 E COG2,COG1,AGE2 GO:0000903 6,5 cellular morphogenesis during vegetative growth 8 0,0012 2 0,0104 0,0208013 E TAO3,CBK1 GO:0006342 12,7,10,5 chromatin silencing 79 0,0122 6 0,0311 0,0212287 E POL2,YCS4,SUB2,IFH1,FKH1,MSI1 GO:0031507 11 heterochromatin formation 79 0,0122 6 0,0311 0,0212287 E POL2,YCS4,SUB2,IFH1,FKH1,MSI1 GO:0016458 6 gene silencing 79 0,0122 6 0,0311 0,0212287 E POL2,YCS4,SUB2,IFH1,FKH1,MSI1 GO:0045814 4 negative regulation of gene expression, epigenetic 79 0,0122 6 0,0311 0,0212287 E POL2,YCS4,SUB2,IFH1,FKH1,MSI1 GO:0051276 6 chromosome organization and biogenesis 255 0,0395 13 0,0674 0,0213321 E POL2,YCS4,TUP1,PDS5,TAF6,SNF12,SAN1,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0006261 8 DNA-dependent DNA replication 80 0,0124 6 0,0311 0,0222768 E POL2,RFA2,POL30,RFC2,CDC47,MGS1 GO:0006613 11,9,7,10,8 cotranslational protein targeting to membrane 22 0,0034 3 0,0155 0,0229665 E SRP68,SRP54,SRP21 GO:0007120 6,8,10,11,9,5 axial bud site selection 22 0,0034 3 0,0155 0,0229665 E CDC11,GIN4,RSR1 GO:0016481 8 negative regulation of transcription 128 0,0198 8 0,0415 0,023288 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0044249 5 cellular biosynthesis 1105 0,1712 25 0,1295 0,0233924 D KTR7,ARO7,STT3,RSM24,HIS7,MNN11,GON7,ALG14,MNN9,MCD4,GAB1,ARO3,HEM1,PMT1,ILV6,YEH2,NMT1,TRP5,ECM31,NAM7,LEU3,DED1,GNA1,LIP5,KTR6 GO:0051321 5 meiotic cell cycle 129 0,02 8 0,0415 0,0241016 E KAR4,DST1,SKI8,CSM1,CSM3,WTM2,BFR1,MEI4 GO:0051327 6 M phase of meiotic cell cycle 129 0,02 8 0,0415 0,0241016 E KAR4,DST1,SKI8,CSM1,CSM3,WTM2,BFR1,MEI4 GO:0007126 7 meiosis 129 0,02 8 0,0415 0,0241016 E KAR4,DST1,SKI8,CSM1,CSM3,WTM2,BFR1,MEI4 GO:0016568 9 chromatin modification 181 0,028 10 0,0518 0,024876 E POL2,YCS4,TAF6,SNF12,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0006357 9 regulation of transcription from RNA polymerase II promoter 181 0,028 10 0,0518 0,024876 E KAR4,FKH2,SPT21,ELP4,HCM1,TAF6,HOT1,IKI1,LEU3,TFB4 GO:0006608 11,9,8,10 snRNP protein import into nucleus 23 0,0036 3 0,0155 0,0256312 E NUP100,NUP133,NUP145 GO:0006607 11,9,8,10 NLS-bearing substrate import into nucleus 23 0,0036 3 0,0155 0,0256312 E NUP100,NUP133,NUP145 GO:0006408 11,9,10,8 snRNA export from nucleus 23 0,0036 3 0,0155 0,0256312 E NUP100,NUP133,NUP145 GO:0006610 11,9,8,10 ribosomal protein import into nucleus 23 0,0036 3 0,0155 0,0256312 E NUP100,NUP133,NUP145 GO:0051030 8,7,9 snRNA transport 23 0,0036 3 0,0155 0,0256312 E NUP100,NUP133,NUP145 GO:0000737 7,8 DNA catabolism, endonucleolytic 9 0,0014 2 0,0104 0,0259521 E SKI8,MEI4 GO:0042278 7 purine nucleoside metabolism 9 0,0014 2 0,0104 0,0259521 E PNP1,DDP1 GO:0006345 11,10,5 loss of chromatin silencing 9 0,0014 2 0,0104 0,0259521 E TBF1,PUF4 GO:0042138 10,8,9 meiotic DNA double-strand break formation 9 0,0014 2 0,0104 0,0259521 E SKI8,MEI4 GO:0006374 10,12 nuclear mRNA splicing via U2-type spliceosome 9 0,0014 2 0,0104 0,0259521 E SUB2,MUD2 GO:0045815 4 positive regulation of gene expression, epigenetic 9 0,0014 2 0,0104 0,0259521 E TBF1,PUF4 GO:0007076 9,8,7 mitotic chromosome condensation 9 0,0014 2 0,0104 0,0259521 E YCS4,PDS5 GO:0007242 5 intracellular signaling cascade 107 0,0166 7 0,0363 0,0262151 E RDI1,WSC2,SIT4,BUD6,RSR1,PTP3,MSI1 GO:0005975 5 carbohydrate metabolism 219 0,0339 2 0,0104 0,027919 D EXG1,GNA1 GO:0000085 7 G2 phase of mitotic cell cycle 1 0,0002 1 0,0052 0,0299039 E FKH2 GO:0048280 7,5,8 vesicle fusion with Golgi apparatus 1 0,0002 1 0,0052 0,0299039 E YIP1 GO:0018008 13,10,12 N-terminal peptidyl-glycine N-myristoylation 1 0,0002 1 0,0052 0,0299039 E NMT1 GO:0000046 6,7 autophagic vacuole fusion 1 0,0002 1 0,0052 0,0299039 E CCZ1 GO:0006570 8,7,9 tyrosine metabolism 1 0,0002 1 0,0052 0,0299039 E TYR1 GO:0009105 8,7 lipoic acid biosynthesis 1 0,0002 1 0,0052 0,0299039 E LIP5 GO:0000273 7,6 lipoic acid metabolism 1 0,0002 1 0,0052 0,0299039 E LIP5 GO:0018201 9 peptidyl-glycine modification 1 0,0002 1 0,0052 0,0299039 E NMT1 GO:0006152 7,8 purine nucleoside catabolism 1 0,0002 1 0,0052 0,0299039 E PNP1 GO:0007090 7 regulation of S phase of mitotic cell cycle 1 0,0002 1 0,0052 0,0299039 E PPS1 GO:0051319 6 G2 phase 1 0,0002 1 0,0052 0,0299039 E FKH2 GO:0015785 8,9 UDP-galactose transport 1 0,0002 1 0,0052 0,0299039 E HUT1 GO:0000116 8,1 G2-specific transcription in mitotic cell cycle 1 0,0002 1 0,0052 0,0299039 E FKH2 GO:0015959 10 diadenosine polyphosphate metabolism 1 0,0002 1 0,0052 0,0299039 E DDP1 GO:0007001 7 chromosome organization and biogenesis (sensu Eukaryota) 243 0,0377 12 0,0622 0,0299607 E POL2,YCS4,TUP1,TAF6,SNF12,SAN1,SUB2,TBF1,IFH1,PUF4,FKH1,MSI1 GO:0009628 4 response to abiotic stimulus 301 0,0466 14 0,0725 0,0307418 E SKI8,SLN1,GON7,HOT1,MXR1,SPL2,WSC2,SCH9,MET30,CBK1,QDR3,BUD6,PTP3,GRX4 GO:0006609 11,9,8,10 mRNA-binding (hnRNP) protein import into nucleus 25 0,0039 3 0,0155 0,0313493 E NUP100,NUP133,NUP145 GO:0008204 7,8,9 ergosterol metabolism 25 0,0039 3 0,0155 0,0313493 E ERG12,ERG6,ERG26 GO:0006696 8,9,10 ergosterol biosynthesis 25 0,0039 3 0,0155 0,0313493 E ERG12,ERG6,ERG26 GO:0000282 7,9,10,8 bud site selection 65 0,0101 5 0,0259 0,0315564 E CDC11,GIN4,BUD16,BUD6,RSR1 GO:0007105 6 cytokinesis, site selection 65 0,0101 5 0,0259 0,0315564 E CDC11,GIN4,BUD16,BUD6,RSR1 GO:0045934 7 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 138 0,0214 8 0,0415 0,0321104 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0006611 10,8,9 protein export from nucleus 45 0,007 4 0,0207 0,0340153 E NOG1,NUP100,NUP133,NUP145 GO:0051031 8,7,9 tRNA transport 26 0,004 3 0,0155 0,034391 E NUP100,NUP133,NUP145 GO:0051029 8,7,9 rRNA transport 26 0,004 3 0,0155 0,034391 E NUP100,NUP133,NUP145 GO:0006409 11,9,10,8 tRNA export from nucleus 26 0,004 3 0,0155 0,034391 E NUP100,NUP133,NUP145 GO:0006407 11,9,10,8 rRNA export from nucleus 26 0,004 3 0,0155 0,034391 E NUP100,NUP133,NUP145 GO:0007165 4 signal transduction 167 0,0259 9 0,0466 0,0345698 E RDI1,KSS1,SLN1,WSC2,SIT4,BUD6,RSR1,PTP3,MSI1 GO:0045229 5 external encapsulating structure organization and biogenesis 141 0,0218 8 0,0415 0,0350406 E KTR7,CDC11,GON7,WSC2,SIT4,EXG1,YEH2,KTR6 GO:0048193 8,6,7 Golgi vesicle transport 141 0,0218 8 0,0415 0,0350406 E COG2,TRS20,YIP1,COG1,VPS53,SLY1,AGE2,ERP1 GO:0007047 6 cell wall organization and biogenesis 141 0,0218 8 0,0415 0,0350406 E KTR7,CDC11,GON7,WSC2,SIT4,EXG1,YEH2,KTR6 GO:0006468 8 protein amino acid phosphorylation 91 0,0141 6 0,0311 0,0356028 E CKA2,GIN4,SLN1,SIT4,SCH9,HSL1 GO:0000082 7 G1/S transition of mitotic cell cycle 46 0,0071 4 0,0207 0,0361563 E CKA2,HCM1,SIT4,CLB5 GO:0016192 5,6 vesicle-mediated transport 282 0,0437 13 0,0674 0,0366535 E COG2,TRS20,YIP1,COG1,VPS53,TLG2,AKL1,SLY1,UBC1,AGE2,YPT31,CCZ1,ERP1 GO:0006301 8,7 postreplication repair 11 0,0017 2 0,0104 0,0373337 E RFA2,POL30 GO:0030261 7 chromosome condensation 11 0,0017 2 0,0104 0,0373337 E YCS4,PDS5 GO:0006308 6,7 DNA catabolism 11 0,0017 2 0,0104 0,0373337 E SKI8,MEI4 GO:0045132 8,5 meiotic chromosome segregation 11 0,0017 2 0,0104 0,0373337 E CSM1,CSM3 GO:0006999 7 nuclear pore organization and biogenesis 27 0,0042 3 0,0155 0,0375463 E NUP100,NUP133,NUP145 GO:0009058 4 biosynthesis 1184 0,1835 29 0,1503 0,0376472 D KTR7,ARO7,STT3,RSM24,ERG12,HIS7,MNN11,ERG6,GON7,ALG14,MNN9,MCD4,ERG26,GAB1,ARO3,HEM1,PMT1,ILV6,YEH2,NMT1,TRP5,ECM31,NAM7,LEU3,DED1,GNA1,LIP5,KTR6,DPH1 GO:0006365 9 35S primary transcript processing 69 0,0107 5 0,0259 0,0381 E RRP7,DBP7,RRP42,RRP43,UTP22 GO:0007154 3 cell communication 199 0,0308 10 0,0518 0,0385361 E RDI1,CKA2,KSS1,SLN1,WSC2,SIT4,BUD6,RSR1,PTP3,MSI1 GO:0045047 10,8,6,9,7 protein targeting to ER 28 0,0043 3 0,0155 0,0408087 E SRP68,SRP54,SRP21 GO:0044262 6 cellular carbohydrate metabolism 201 0,0311 2 0,0104 0,0411213 D EXG1,GNA1 GO:0006997 6 nuclear organization and biogenesis 49 0,0076 4 0,0207 0,0429114 E KAR4,NUP100,NUP133,NUP145 GO:0006364 8 rRNA processing 176 0,0273 9 0,0466 0,0429179 E BUD21,RRP7,DBP7,NGL2,IFH1,RRP42,RRP43,LSM5,UTP22 GO:0007234 7,6 osmosensory signaling pathway via two-component system 12 0,0019 2 0,0104 0,0434723 E SLN1,PTP3 GO:0006057 8,7 mannoprotein biosynthesis 12 0,0019 2 0,0104 0,0434723 E GON7,YEH2 GO:0006056 7 mannoprotein metabolism 12 0,0019 2 0,0104 0,0434723 E GON7,YEH2 GO:0000160 5 two-component signal transduction system (phosphorelay) 12 0,0019 2 0,0104 0,0434723 E SLN1,PTP3 GO:0006268 9 DNA unwinding during replication 12 0,0019 2 0,0104 0,0434723 E RFA2,CDC47 GO:0031506 7,9,8 cell wall glycoprotein biosynthesis 12 0,0019 2 0,0104 0,0434723 E GON7,YEH2 GO:0000032 8,10,9 cell wall mannoprotein biosynthesis 12 0,0019 2 0,0104 0,0434723 E GON7,YEH2 GO:0007103 9,6 spindle pole body duplication in nuclear envelope 12 0,0019 2 0,0104 0,0434723 E BBP1,NDC1 GO:0006974 5 response to DNA damage stimulus 177 0,0274 9 0,0466 0,0438919 E POL2,CKA2,RFA2,MSH1,POL30,RFC2,SIT4,PDS1,MSI1 GO:0000910 5 cytokinesis 97 0,015 6 0,0311 0,0441282 E CDC11,GIN4,BUD16,BNI5,BUD6,RSR1 GO:0016126 7,8,9 sterol biosynthesis 29 0,0045 3 0,0155 0,0441716 E ERG12,ERG6,ERG26 GO:0006281 7,6 DNA repair 150 0,0232 8 0,0415 0,0445226 E POL2,RFA2,MSH1,POL30,RFC2,SIT4,PDS1,MSI1 GO:0031324 6 negative regulation of cellular metabolism 150 0,0232 8 0,0415 0,0445226 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0048519 3 negative regulation of biological process 178 0,0276 9 0,0466 0,0448742 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,PTP3,MSI1,TFB4 GO:0045892 9 negative regulation of transcription, DNA-dependent 124 0,0192 7 0,0363 0,0456128 E POL2,YCS4,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0008652 7,8 amino acid biosynthesis 99 0,0153 6 0,0311 0,0471379 E ARO7,HIS7,ARO3,ILV6,TRP5,LEU3 GO:0030474 8,5 spindle pole body duplication 13 0,002 2 0,0104 0,0498531 E BBP1,NDC1 GO:0051300 7 spindle pole body organization and biogenesis 13 0,002 2 0,0104 0,0498531 E BBP1,NDC1 GO:0031023 6 microtubule organizing center organization and biogenesis 13 0,002 2 0,0104 0,0498531 E BBP1,NDC1 GO:0009082 8,9 branched chain family amino acid biosynthesis 13 0,002 2 0,0104 0,0498531 E ILV6,LEU3 GO:0009719 4 response to endogenous stimulus 183 0,0284 9 0,0466 0,049902 E POL2,CKA2,RFA2,MSH1,POL30,RFC2,SIT4,PDS1,MSI1 GO:0006979 6,5 response to oxidative stress 52 0,0081 4 0,0207 0,0501175 E SLN1,MXR1,SCH9,GRX4 GO:0006612 10,8,9 protein targeting to membrane 31 0,0048 3 0,0155 0,0511716 E SRP68,SRP54,SRP21 GO:0006289 8,7 nucleotide-excision repair 31 0,0048 3 0,0155 0,0511716 E POL2,RFA2,POL30 GO:0007046 7 ribosome biogenesis 214 0,0332 10 0,0518 0,051871 E BUD21,RRP7,NOG1,DBP7,NGL2,IFH1,RRP42,RRP43,LSM5,UTP22 GO:0009892 5 negative regulation of metabolism 157 0,0243 8 0,0415 0,0525038 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0030010 7,8,6 establishment of cell polarity 103 0,016 6 0,0311 0,053375 E CKA2,CDC11,GIN4,BUD16,BUD6,RSR1 GO:0030468 8,9,7 establishment of cell polarity (sensu Fungi) 103 0,016 6 0,0311 0,053375 E CKA2,CDC11,GIN4,BUD16,BUD6,RSR1 GO:0006399 7 tRNA metabolism 103 0,016 6 0,0311 0,053375 E THG1,TRM11,PUS1,NUP145,GCD14,CCA1 GO:0006800 5 oxygen and reactive oxygen species metabolism 54 0,0084 4 0,0207 0,0551394 E SLN1,MXR1,SCH9,GRX4 GO:0030488 9 tRNA methylation 14 0,0022 2 0,0104 0,0564372 E TRM11,GCD14 GO:0009116 6 nucleoside metabolism 14 0,0022 2 0,0104 0,0564372 E PNP1,DDP1 GO:0015781 7,8 pyrimidine nucleotide-sugar transport 2 0,0003 1 0,0052 0,0580284 E HUT1 GO:0009847 4 spore germination 2 0,0003 1 0,0052 0,0580284 E UBC1 GO:0018195 9 peptidyl-arginine modification 2 0,0003 1 0,0052 0,0580284 E HMT1 GO:0000078 7 cell morphogenesis checkpoint 2 0,0003 1 0,0052 0,0580284 E HSL1 GO:0051503 8,9 adenine nucleotide transport 2 0,0003 1 0,0052 0,0580284 E MCD4 GO:0006048 10,11,8 UDP-N-acetylglucosamine biosynthesis 2 0,0003 1 0,0052 0,0580284 E GNA1 GO:0006047 9,7,10 UDP-N-acetylglucosamine metabolism 2 0,0003 1 0,0052 0,0580284 E GNA1 GO:0016236 5 macroautophagy 2 0,0003 1 0,0052 0,0580284 E CCZ1 GO:0015867 9,1 ATP transport 2 0,0003 1 0,0052 0,0580284 E MCD4 GO:0010032 8 meiotic chromosome condensation 2 0,0003 1 0,0052 0,0580284 E YCS4 GO:0001302 6,5 replicative cell aging 33 0,0051 3 0,0155 0,0584911 E SIT4,SCH9,PUF4 GO:0007127 8 meiosis I 56 0,0087 4 0,0207 0,0603115 E DST1,SKI8,CSM1,MEI4 GO:0009309 6,7 amine biosynthesis 108 0,0167 6 0,0311 0,0615138 E ARO7,HIS7,ARO3,ILV6,TRP5,LEU3 GO:0044271 6,5 nitrogen compound biosynthesis 108 0,0167 6 0,0311 0,0615138 E ARO7,HIS7,ARO3,ILV6,TRP5,LEU3 GO:0000003 2 reproduction 255 0,0395 11 0,057 0,0617148 E TOS2,KAR4,CDC11,GIN4,TAO3,OPY1,CBK1,BUD6,RSR1,PTP3,MEI4 GO:0006725 5 aromatic compound metabolism 57 0,0088 4 0,0207 0,0629472 E TYR1,ARO7,ARO3,TRP5 GO:0007231 6 osmosensory signaling pathway 15 0,0023 2 0,0104 0,0631885 E SLN1,PTP3 GO:0006311 9,8 meiotic gene conversion 15 0,0023 2 0,0104 0,0631885 E SKI8,MEI4 GO:0001510 8 RNA methylation 15 0,0023 2 0,0104 0,0631885 E TRM11,GCD14 GO:0048523 4 negative regulation of cellular process 170 0,0263 8 0,0415 0,0682619 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0051243 5 negative regulation of cellular physiological process 170 0,0263 8 0,0415 0,0682619 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0000226 8 microtubule cytoskeleton organization and biogenesis 85 0,0132 5 0,0259 0,0688957 E HCM1,BBP1,TUB4,NDC1,SPC25 GO:0019538 5 protein metabolism 1424 0,2206 43 0,2228 0,0697402 E KTR7,CKA2,NAT5,NAT2,STT3,GIN4,HMT1,RRP7,SKI8,HSH155,RSM24,MNN11,SLN1,TAF6,GON7,CCT8,DBP7,ALG14,PPS1,SIT4,MNN9,MCD4,SCH9,GAB1,PRP19,SAN1,SUB2,MET30,PMT1,KAE1,YEH2,NMT1,UBC1,NAM7,HSL1,PTP3,DED1,MSI1,KTR6,OAZ1,CCT7,MUD2,DPH1 GO:0044260 5 cellular macromolecule metabolism 1448 0,2244 43 0,2228 0,0698181 D KTR7,CKA2,NAT5,NAT2,STT3,GIN4,HMT1,RRP7,SKI8,HSH155,RSM24,MNN11,SLN1,TAF6,GON7,CCT8,DBP7,ALG14,PPS1,SIT4,MNN9,MCD4,SCH9,GAB1,PRP19,SAN1,SUB2,EXG1,MET30,PMT1,KAE1,YEH2,NMT1,UBC1,NAM7,HSL1,PTP3,DED1,MSI1,KTR6,CCT7,MUD2,DPH1 GO:0006694 7,6,8 steroid biosynthesis 36 0,0056 3 0,0155 0,0699476 E ERG12,ERG6,ERG26 GO:0042158 8,7 lipoprotein biosynthesis 36 0,0056 3 0,0155 0,0699476 E MCD4,GAB1,NMT1 GO:0042157 7 lipoprotein metabolism 36 0,0056 3 0,0155 0,0699476 E MCD4,GAB1,NMT1 GO:0006497 9,8 protein lipidation 36 0,0056 3 0,0155 0,0699476 E MCD4,GAB1,NMT1 GO:0009081 7,8 branched chain family amino acid metabolism 16 0,0025 2 0,0104 0,0700733 E ILV6,LEU3 GO:0044267 6 cellular protein metabolism 1400 0,2169 42 0,2176 0,070493 E KTR7,CKA2,NAT5,NAT2,STT3,GIN4,HMT1,RRP7,SKI8,HSH155,RSM24,MNN11,SLN1,TAF6,GON7,CCT8,DBP7,ALG14,PPS1,SIT4,MNN9,MCD4,SCH9,GAB1,PRP19,SAN1,SUB2,MET30,PMT1,KAE1,YEH2,NMT1,UBC1,NAM7,HSL1,PTP3,DED1,MSI1,KTR6,CCT7,MUD2,DPH1 GO:0043118 4 negative regulation of physiological process 172 0,0267 8 0,0415 0,070748 E POL2,YCS4,TUP1,SUB2,IFH1,FKH1,MSI1,TFB4 GO:0006807 4 nitrogen compound metabolism 236 0,0366 10 0,0518 0,073078 E TYR1,ARO7,DCG1,HIS7,ARO3,ILV6,TRP5,LEU3,PRO3,GNA1 GO:0030471 4 spindle pole body and microtubule cycle (sensu Fungi) 37 0,0057 3 0,0155 0,0738659 E BBP1,TUB4,NDC1 GO:0048284 6 organelle fusion 17 0,0026 2 0,0104 0,0770604 E KAR4,CCZ1 GO:0007266 7 Rho protein signal transduction 17 0,0026 2 0,0104 0,0770604 E WSC2,BUD6 GO:0006473 8 protein amino acid acetylation 38 0,0059 3 0,0155 0,0778228 E NAT5,NAT2,TAF6 GO:0006461 7 protein complex assembly 148 0,0229 7 0,0363 0,0790417 E RRP7,SKI8,HSH155,DBP7,SUB2,MSI1,MUD2 GO:0007131 9,8 meiotic recombination 39 0,006 3 0,0155 0,0818113 E DST1,SKI8,MEI4 GO:0006520 6,7 amino acid metabolism 182 0,0282 8 0,0415 0,0832039 E TYR1,ARO7,HIS7,ARO3,ILV6,TRP5,LEU3,PRO3 GO:0006378 10 mRNA polyadenylylation 18 0,0028 2 0,0104 0,0841205 E YSH1,FIP1 GO:0006449 10,9,8 regulation of translational termination 3 0,0005 1 0,0052 0,0844523 E NAM7 GO:0030100 6,7,8 regulation of endocytosis 3 0,0005 1 0,0052 0,0844523 E AKL1 GO:0006862 6,7 nucleotide transport 3 0,0005 1 0,0052 0,0844523 E MCD4 GO:0015865 7,8 purine nucleotide transport 3 0,0005 1 0,0052 0,0844523 E MCD4 GO:0017196 12,1 N-terminal peptidyl-methionine acetylation 3 0,0005 1 0,0052 0,0844523 E NAT2 GO:0006452 10,9,8 translational frameshifting 3 0,0005 1 0,0052 0,0844523 E NAM7 GO:0018206 9 peptidyl-methionine modification 3 0,0005 1 0,0052 0,0844523 E NAT2 GO:0016584 11 nucleosome spacing 3 0,0005 1 0,0052 0,0844523 E TUP1 GO:0006561 9,1 proline biosynthesis 3 0,0005 1 0,0052 0,0844523 E PRO3 GO:0042542 8,7 response to hydrogen peroxide 3 0,0005 1 0,0052 0,0844523 E SLN1 GO:0009308 5 amine metabolism 218 0,0338 9 0,0466 0,0875718 E TYR1,ARO7,HIS7,ARO3,ILV6,TRP5,LEU3,PRO3,GNA1 GO:0007028 5 cytoplasm organization and biogenesis 253 0,0392 10 0,0518 0,0892787 E BUD21,RRP7,NOG1,DBP7,NGL2,IFH1,RRP42,RRP43,LSM5,UTP22 GO:0042254 6 ribosome biogenesis and assembly 253 0,0392 10 0,0518 0,0892787 E BUD21,RRP7,NOG1,DBP7,NGL2,IFH1,RRP42,RRP43,LSM5,UTP22 GO:0042221 5 response to chemical stimulus 220 0,0341 9 0,0466 0,0896835 E SKI8,SLN1,MXR1,SCH9,MET30,CBK1,QDR3,PTP3,GRX4 GO:0007569 5,4 cell aging 41 0,0064 3 0,0155 0,0898577 E SIT4,SCH9,PUF4 GO:0006793 5 phosphorus metabolism 188 0,0291 8 0,0415 0,0905689 E CKA2,GIN4,SLN1,PPS1,SIT4,SCH9,HSL1,PTP3 GO:0006796 6 phosphate metabolism 188 0,0291 8 0,0415 0,0905689 E CKA2,GIN4,SLN1,PPS1,SIT4,SCH9,HSL1,PTP3 GO:0007568 3,4 aging 42 0,0065 3 0,0155 0,0939028 E SIT4,SCH9,PUF4 GO:0007243 6 protein kinase cascade 20 0,0031 2 0,0104 0,0983547 E SIT4,PTP3 GO:0009266 5 response to temperature stimulus 20 0,0031 2 0,0104 0,0983547 E SPL2,WSC2 GO:0030036 8 actin cytoskeleton organization and biogenesis 100 0,0155 5 0,0259 0,1008359 E RDI1,WSC2,SIT4,AKL1,BUD6 GO:0007017 7 microtubule-based process 100 0,0155 5 0,0259 0,1008359 E HCM1,BBP1,TUB4,NDC1,SPC25 GO:0006519 5 amino acid and derivative metabolism 197 0,0305 8 0,0415 0,1012199 E TYR1,ARO7,HIS7,ARO3,ILV6,TRP5,LEU3,PRO3 GO:0006367 9 transcription initiation from RNA polymerase II promoter 44 0,0068 3 0,0155 0,1020063 E HCM1,TAF6,TFB4 GO:0051338 4 regulation of transferase activity 21 0,0033 2 0,0104 0,1054807 E CLB5,PTP3 GO:0045859 5 regulation of protein kinase activity 21 0,0033 2 0,0104 0,1054807 E CLB5,PTP3 GO:0006348 13,8,11,6 chromatin silencing at telomere 45 0,007 3 0,0155 0,1060529 E POL2,SUB2,IFH1 GO:0031509 12 telomeric heterochromatin formation 45 0,007 3 0,0155 0,1060529 E POL2,SUB2,IFH1 GO:0030029 7 actin filament-based process 104 0,0161 5 0,0259 0,1092235 E RDI1,WSC2,SIT4,AKL1,BUD6 GO:0046686 8 response to cadmium ion 4 0,0006 1 0,0052 0,1092517 E MET30 GO:0006279 8 premeiotic DNA synthesis 4 0,0006 1 0,0052 0,1092517 E CLB5 GO:0006085 8 acetyl-CoA biosynthesis 4 0,0006 1 0,0052 0,1092517 E ACS2 GO:0009164 6,7 nucleoside catabolism 4 0,0006 1 0,0052 0,1092517 E PNP1 GO:0015780 6,7 nucleotide-sugar transport 4 0,0006 1 0,0052 0,1092517 E HUT1 GO:0006356 9 regulation of transcription from RNA polymerase I promoter 4 0,0006 1 0,0052 0,1092517 E CKA2 GO:0000731 8,7 DNA synthesis during DNA repair 4 0,0006 1 0,0052 0,1092517 E POL2 GO:0030007 8 potassium ion homeostasis 4 0,0006 1 0,0052 0,1092517 E TRK1 GO:0008219 4 cell death 46 0,0071 3 0,0155 0,1100885 E SIT4,SCH9,PUF4 GO:0000747 6,4 conjugation with cellular fusion 105 0,0163 5 0,0259 0,1112892 E KAR4,CDC11,OPY1,CBK1,PTP3 GO:0019953 3 sexual reproduction 105 0,0163 5 0,0259 0,1112892 E KAR4,CDC11,OPY1,CBK1,PTP3 GO:0000746 5 conjugation 105 0,0163 5 0,0259 0,1112892 E KAR4,CDC11,OPY1,CBK1,PTP3 GO:0009057 5 macromolecule catabolism 280 0,0434 10 0,0518 0,1113645 E SKI8,PRP19,SAN1,MET30,NAM7,RRP42,PUF4,RRP43,LSM5,OAZ1 GO:0030466 13,8,11,6 chromatin silencing at silent mating-type cassette 22 0,0034 2 0,0104 0,1125838 E YCS4,FKH1 GO:0016265 3 death 47 0,0073 3 0,0155 0,1141078 E SIT4,SCH9,PUF4 GO:0009056 4 catabolism 369 0,0572 12 0,0622 0,1147697 E PNP1,SKI8,PRP19,SAN1,MET30,NAM7,RRP42,PUF4,RRP43,LSM5,OAZ1,MEI4 GO:0007088 8,6 regulation of mitosis 48 0,0074 3 0,0155 0,1181056 E IBD2,BFR1,CBK1 GO:0051318 6 G1 phase 23 0,0036 2 0,0104 0,1196444 E TAF6,CDC50 GO:0000080 7 G1 phase of mitotic cell cycle 23 0,0036 2 0,0104 0,1196444 E TAF6,CDC50 GO:0006506 10,11,9,12 GPI anchor biosynthesis 23 0,0036 2 0,0104 0,1196444 E MCD4,GAB1 GO:0016310 7 phosphorylation 143 0,0222 6 0,0311 0,1201652 E CKA2,GIN4,SLN1,SIT4,SCH9,HSL1 GO:0016072 7 rRNA metabolism 254 0,0394 9 0,0466 0,1203867 E BUD21,RRP7,DBP7,NGL2,IFH1,RRP42,RRP43,LSM5,UTP22 GO:0044248 5 cellular catabolism 347 0,0538 11 0,057 0,1224404 E PNP1,SKI8,PRP19,SAN1,MET30,NAM7,RRP42,PUF4,RRP43,LSM5,MEI4 GO:0044265 6 cellular macromolecule catabolism 258 0,04 9 0,0466 0,1231062 E SKI8,PRP19,SAN1,MET30,NAM7,RRP42,PUF4,RRP43,LSM5 GO:0046489 10,9,11 phosphoinositide biosynthesis 24 0,0037 2 0,0104 0,1266447 E MCD4,GAB1 GO:0006505 10,11 GPI anchor metabolism 24 0,0037 2 0,0104 0,1266447 E MCD4,GAB1 GO:0040007 2 growth 113 0,0175 5 0,0259 0,12718 E TOS2,FKH2,GIN4,KSS1,FKH1 GO:0030435 4 sporulation 105 0,0163 1 0,0052 0,1322739 D MEI4 GO:0016255 11,12,10,13 attachment of GPI anchor to protein 5 0,0008 1 0,0052 0,1324995 E GAB1 GO:0007346 6 regulation of progression through mitotic cell cycle 5 0,0008 1 0,0052 0,1324995 E PPS1 GO:0045143 9,6 homologous chromosome segregation 5 0,0008 1 0,0052 0,1324995 E CSM1 GO:0018202 9 peptidyl-histidine modification 5 0,0008 1 0,0052 0,1324995 E DPH1 GO:0000173 9,8 inactivation of MAPK activity during osmolarity sensing 5 0,0008 1 0,0052 0,1324995 E PTP3 GO:0017183 11,5 peptidyl-diphthamide biosynthesis from peptidyl-histidine 5 0,0008 1 0,0052 0,1324995 E DPH1 GO:0000188 8 inactivation of MAPK activity 5 0,0008 1 0,0052 0,1324995 E PTP3 GO:0030026 8,9 manganese ion homeostasis 5 0,0008 1 0,0052 0,1324995 E ATX2 GO:0006816 8,9 calcium ion transport 5 0,0008 1 0,0052 0,1324995 E MID1 GO:0017182 10 peptidyl-diphthamide metabolism 5 0,0008 1 0,0052 0,1324995 E DPH1 GO:0018377 10,9 protein myristoylation 5 0,0008 1 0,0052 0,1324995 E NMT1 GO:0009098 9,1 leucine biosynthesis 5 0,0008 1 0,0052 0,1324995 E LEU3 GO:0006499 12,11 N-terminal protein myristoylation 5 0,0008 1 0,0052 0,1324995 E NMT1 GO:0043407 7 negative regulation of MAPK activity 5 0,0008 1 0,0052 0,1324995 E PTP3 GO:0018319 11,1 protein amino acid myristoylation 5 0,0008 1 0,0052 0,1324995 E NMT1 GO:0015677 10,11 copper ion import 5 0,0008 1 0,0052 0,1324995 E FRE1 GO:0000076 8 DNA replication checkpoint 5 0,0008 1 0,0052 0,1324995 E CSM3 GO:0009225 6 nucleotide-sugar metabolism 5 0,0008 1 0,0052 0,1324995 E GNA1 GO:0006334 11,8 nucleosome assembly 5 0,0008 1 0,0052 0,1324995 E MSI1 GO:0050790 3 regulation of enzyme activity 25 0,0039 2 0,0104 0,1335683 E CLB5,PTP3 GO:0006082 5 organic acid metabolism 300 0,0465 9 0,0466 0,136999 E TYR1,ARO7,HIS7,ARO3,ILV6,TRP5,LEU3,PRO3,LIP5 GO:0019752 6 carboxylic acid metabolism 300 0,0465 9 0,0466 0,136999 E TYR1,ARO7,HIS7,ARO3,ILV6,TRP5,LEU3,PRO3,LIP5 GO:0006470 8 protein amino acid dephosphorylation 26 0,004 2 0,0104 0,1404001 E PPS1,PTP3 GO:0006352 8 transcription initiation 55 0,0085 3 0,0155 0,1450877 E HCM1,TAF6,TFB4 GO:0008610 6,5,7 lipid biosynthesis 124 0,0192 5 0,0259 0,1464668 E ERG12,ERG6,MCD4,ERG26,GAB1 GO:0044255 5,6 cellular lipid metabolism 208 0,0322 7 0,0363 0,146832 E ARV1,ERG12,ERG6,MCD4,ERG26,GAB1,YEH2 GO:0009451 7 RNA modification 126 0,0195 5 0,0259 0,1495764 E THG1,TRM11,PUS1,GCD14,CCA1 GO:0006629 5 lipid metabolism 222 0,0344 7 0,0363 0,1526388 E ARV1,ERG12,ERG6,MCD4,ERG26,GAB1,YEH2 GO:0006360 8 transcription from RNA polymerase I promoter 28 0,0043 2 0,0104 0,1537353 E RRN3,CKA2 GO:0046685 7 response to arsenic 6 0,0009 1 0,0052 0,1542656 E MET30 GO:0051348 5 negative regulation of transferase activity 6 0,0009 1 0,0052 0,1542656 E PTP3 GO:0018409 10 peptide or protein amino-terminal blocking 6 0,0009 1 0,0052 0,1542656 E NAT2 GO:0006415 9,8 translational termination 6 0,0009 1 0,0052 0,1542656 E NAM7 GO:0015918 6,7 sterol transport 6 0,0009 1 0,0052 0,1542656 E ARV1 GO:0006469 6 negative regulation of protein kinase activity 6 0,0009 1 0,0052 0,1542656 E PTP3 GO:0006474 11,9 N-terminal protein amino acid acetylation 6 0,0009 1 0,0052 0,1542656 E NAT2 GO:0043405 6 regulation of MAPK activity 6 0,0009 1 0,0052 0,1542656 E PTP3 GO:0043086 4 negative regulation of enzyme activity 6 0,0009 1 0,0052 0,1542656 E PTP3 GO:0031365 9 N-terminal protein amino acid modification 6 0,0009 1 0,0052 0,1542656 E NAT2 GO:0001402 5,4 signal transduction during filamentous growth 6 0,0009 1 0,0052 0,1542656 E KSS1 GO:0045893 9 positive regulation of transcription, DNA-dependent 59 0,0091 3 0,0155 0,1593599 E KAR4,TBF1,PUF4 GO:0007005 6 mitochondrion organization and biogenesis 95 0,0147 1 0,0052 0,1626496 D MRS11 GO:0050876 3 reproductive physiological process 192 0,0297 6 0,0311 0,1647752 E KAR4,CDC11,OPY1,CBK1,PTP3,MEI4 GO:0048610 4 reproductive cellular physiological process 192 0,0297 6 0,0311 0,1647752 E KAR4,CDC11,OPY1,CBK1,PTP3,MEI4 GO:0006906 6,4,7 vesicle fusion 30 0,0046 2 0,0104 0,166556 E YIP1,TLG2 GO:0007117 6,4,5 budding cell bud growth 30 0,0046 2 0,0104 0,166556 E TOS2,GIN4 GO:0048590 3 non-developmental growth 30 0,0046 2 0,0104 0,166556 E TOS2,GIN4 GO:0030437 6 sporulation (sensu Fungi) 92 0,0143 1 0,0052 0,1726828 D MEI4 GO:0048622 5 reproductive sporulation 92 0,0143 1 0,0052 0,1726828 D MEI4 GO:0030384 9,1 phosphoinositide metabolism 31 0,0048 2 0,0104 0,1727491 E MCD4,GAB1 GO:0006310 7 DNA recombination 189 0,0293 5 0,0259 0,1728741 D RFA2,DST1,SKI8,PDS1,MEI4 GO:0051186 5 cofactor metabolism 148 0,0229 5 0,0259 0,1741461 E NAR1,HEM1,ACS2,ECM31,LIP5 GO:0006560 8,9 proline metabolism 7 0,0011 1 0,0052 0,1746175 E PRO3 GO:0031146 12,13 SCF-dependent proteasomal ubiquitin-dependent protein catabolism 7 0,0011 1 0,0052 0,1746175 E MET30 GO:0009613 6,5 response to pest, pathogen or parasite 7 0,0011 1 0,0052 0,1746175 E SKI8 GO:0001306 7,6 age-dependent response to oxidative stress 7 0,0011 1 0,0052 0,1746175 E SCH9 GO:0043331 6 response to dsRNA 7 0,0011 1 0,0052 0,1746175 E SKI8 GO:0001324 8,7 age-dependent response to oxidative stress during chronological cell aging 7 0,0011 1 0,0052 0,1746175 E SCH9 GO:0043330 7,8 response to exogenous dsRNA 7 0,0011 1 0,0052 0,1746175 E SKI8 GO:0009615 7,6 response to virus 7 0,0011 1 0,0052 0,1746175 E SKI8 GO:0006551 8,9 leucine metabolism 7 0,0011 1 0,0052 0,1746175 E LEU3 GO:0043207 5 response to external biotic stimulus 7 0,0011 1 0,0052 0,1746175 E SKI8 GO:0006269 11 DNA replication, synthesis of RNA primer 7 0,0011 1 0,0052 0,1746175 E RFA2 GO:0006972 6 hyperosmotic response 7 0,0011 1 0,0052 0,1746175 E HOT1 GO:0006280 7 mutagenesis 7 0,0011 1 0,0052 0,1746175 E POL30 GO:0009607 4 response to biotic stimulus 7 0,0011 1 0,0052 0,1746175 E SKI8 GO:0000302 7,6 response to reactive oxygen species 7 0,0011 1 0,0052 0,1746175 E SLN1 GO:0006359 9 regulation of transcription from RNA polymerase III promoter 7 0,0011 1 0,0052 0,1746175 E CKA2 GO:0001323 7,6 age-dependent general metabolic decline during chronological cell aging 7 0,0011 1 0,0052 0,1746175 E SCH9 GO:0045941 8 positive regulation of transcription 65 0,0101 3 0,0155 0,1786628 E KAR4,TBF1,PUF4 GO:0007121 6,8,10,11,9,5 bipolar bud site selection 32 0,005 2 0,0104 0,1787862 E BUD6,RSR1 GO:0016044 5 membrane organization and biogenesis 32 0,005 2 0,0104 0,1787862 E SEY1,MRS11 GO:0006066 5 alcohol metabolism 157 0,0243 5 0,0259 0,178831 E ARV1,ERG12,ERG6,ERG26,YEH2 GO:0009117 6 nucleotide metabolism 90 0,0139 1 0,0052 0,1796033 D HIS7 GO:0045935 7 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 66 0,0102 3 0,0155 0,1816044 E KAR4,TBF1,PUF4 GO:0045333 7 cellular respiration 89 0,0138 1 0,0052 0,1831319 D RSM24 GO:0009893 5 positive regulation of metabolism 68 0,0105 3 0,0155 0,1872354 E KAR4,TBF1,PUF4 GO:0031325 6 positive regulation of cellular metabolism 68 0,0105 3 0,0155 0,1872354 E KAR4,TBF1,PUF4 GO:0043285 5,6 biopolymer catabolism 157 0,0243 4 0,0207 0,188899 D PRP19,SAN1,MET30,OAZ1 GO:0006508 7 proteolysis 157 0,0243 4 0,0207 0,188899 D PRP19,SAN1,MET30,KAE1 GO:0046474 9,8,10 glycerophospholipid biosynthesis 34 0,0053 2 0,0104 0,1903654 E MCD4,GAB1 GO:0001308 8,12,11,7,6 loss of chromatin silencing during replicative cell aging 8 0,0012 1 0,0052 0,1936196 E PUF4 GO:0046128 8 purine ribonucleoside metabolism 8 0,0012 1 0,0052 0,1936196 E DDP1 GO:0051049 5,6 regulation of transport 8 0,0012 1 0,0052 0,1936196 E AKL1 GO:0006275 9,8 regulation of DNA replication 8 0,0012 1 0,0052 0,1936196 E MGS1 GO:0015939 8 pantothenate metabolism 8 0,0012 1 0,0052 0,1936196 E ECM31 GO:0006855 6,7,8 multidrug transport 8 0,0012 1 0,0052 0,1936196 E QDR3 GO:0007571 6,5 age-dependent general metabolic decline 8 0,0012 1 0,0052 0,1936196 E SCH9 GO:0015940 8,9 pantothenate biosynthesis 8 0,0012 1 0,0052 0,1936196 E ECM31 GO:0048522 4 positive regulation of cellular process 71 0,011 3 0,0155 0,1950325 E KAR4,TBF1,PUF4 GO:0051188 6 cofactor biosynthesis 71 0,011 3 0,0155 0,1950325 E HEM1,ECM31,LIP5 GO:0051242 5 positive regulation of cellular physiological process 71 0,011 3 0,0155 0,1950325 E KAR4,TBF1,PUF4 GO:0046483 5 heterocycle metabolism 71 0,011 3 0,0155 0,1950325 E HEM1,TRP5,LIP5 GO:0043119 4 positive regulation of physiological process 71 0,011 3 0,0155 0,1950325 E KAR4,TBF1,PUF4 GO:0016311 7 dephosphorylation 35 0,0054 2 0,0104 0,1958959 E PPS1,PTP3 GO:0043414 7 biopolymer methylation 35 0,0054 2 0,0104 0,1958959 E TRM11,GCD14 GO:0030163 6,7 protein catabolism 145 0,0225 4 0,0207 0,1974047 D PRP19,SAN1,MET30,OAZ1 GO:0009060 8 aerobic respiration 84 0,013 1 0,0052 0,2014337 D RSM24 GO:0007031 6 peroxisome organization and biogenesis 37 0,0057 2 0,0104 0,2064158 E PEX15,PEX31 GO:0006865 6,7,8 amino acid transport 37 0,0057 2 0,0104 0,2064158 E VBA1,BAP3 GO:0006811 5,6 ion transport 107 0,0166 2 0,0104 0,2095427 D MID1,FRE1 GO:0030154 3 cell differentiation 107 0,0166 2 0,0104 0,2095427 D UBC1,MEI4 GO:0048518 3 positive regulation of biological process 78 0,0121 3 0,0155 0,2100827 E KAR4,TBF1,PUF4 GO:0031163 6 metallo-sulfur cluster assembly 9 0,0014 1 0,0052 0,211334 E NAR1 GO:0045039 11,8,9,7,10 protein import into mitochondrial inner membrane 9 0,0014 1 0,0052 0,211334 E MRS11 GO:0016226 7 iron-sulfur cluster assembly 9 0,0014 1 0,0052 0,211334 E NAR1 GO:0000501 7,6 flocculation (sensu Saccharomyces) 9 0,0014 1 0,0052 0,211334 E CKA2 GO:0000161 8,7 MAPKKK cascade during osmolarity sensing 9 0,0014 1 0,0052 0,211334 E PTP3 GO:0046021 9,1 regulation of transcription from RNA polymerase II promoter, mitotic 9 0,0014 1 0,0052 0,211334 E TFB4 GO:0015802 7,8,9 basic amino acid transport 9 0,0014 1 0,0052 0,211334 E VBA1 GO:0007070 10,11 negative regulation of transcription from RNA polymerase II promoter, mitotic 9 0,0014 1 0,0052 0,211334 E TFB4 GO:0000128 5 flocculation 9 0,0014 1 0,0052 0,211334 E CKA2 GO:0000184 9 mRNA catabolism, nonsense-mediated decay 9 0,0014 1 0,0052 0,211334 E NAM7 GO:0001304 7,6 progressive alteration of chromatin during replicative cell aging 9 0,0014 1 0,0052 0,211334 E PUF4 GO:0016339 6 calcium-dependent cell-cell adhesion 9 0,0014 1 0,0052 0,211334 E CKA2 GO:0006383 8 transcription from RNA polymerase III promoter 38 0,0059 2 0,0104 0,2113981 E CKA2,IFH1 GO:0044257 7,8 cellular protein catabolism 123 0,0191 3 0,0155 0,2131734 D PRP19,SAN1,MET30 GO:0051603 8,9 proteolysis during cellular protein catabolism 123 0,0191 3 0,0155 0,2131734 D PRP19,SAN1,MET30 GO:0006511 10,11 ubiquitin-dependent protein catabolism 121 0,0187 3 0,0155 0,2156037 D PRP19,SAN1,MET30 GO:0019941 9,1 modification-dependent protein catabolism 121 0,0187 3 0,0155 0,2156037 D PRP19,SAN1,MET30 GO:0006732 6 coenzyme metabolism 119 0,0184 3 0,0155 0,2178759 D ACS2,ECM31,LIP5 GO:0007166 5 cell surface receptor linked signal transduction 40 0,0062 2 0,0104 0,2207946 E SLN1,PTP3 GO:0042592 3 homeostasis 114 0,0177 3 0,0155 0,2227858 D CKA2,TRK1,ATX2 GO:0030447 3 filamentous growth 87 0,0135 3 0,0155 0,2228984 E FKH2,KSS1,FKH1 GO:0019725 4 cell homeostasis 108 0,0167 3 0,0155 0,2270074 D CKA2,TRK1,ATX2 GO:0006284 8,7 base-excision repair 10 0,0015 1 0,0052 0,2278203 E POL30 GO:0000742 8,7,5 karyogamy during conjugation with cellular fusion 10 0,0015 1 0,0052 0,2278203 E KAR4 GO:0045896 8,9 regulation of transcription, mitotic 10 0,0015 1 0,0052 0,2278203 E TFB4 GO:0006586 7,8 indolalkylamine metabolism 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0046219 8,9,7 indolalkylamine biosynthesis 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0009119 7 ribonucleoside metabolism 10 0,0015 1 0,0052 0,2278203 E DDP1 GO:0000162 10,9,8,11 tryptophan biosynthesis 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0009269 7,6 response to desiccation 10 0,0015 1 0,0052 0,2278203 E GON7 GO:0042147 9,8,7 retrograde transport, endosome to Golgi 10 0,0015 1 0,0052 0,2278203 E VPS53 GO:0001301 6,5 progressive alteration of chromatin during cell aging 10 0,0015 1 0,0052 0,2278203 E PUF4 GO:0006488 11,1 dolichol-linked oligosaccharide biosynthesis 10 0,0015 1 0,0052 0,2278203 E ALG14 GO:0042434 7 indole derivative metabolism 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0006568 8,9,7 tryptophan metabolism 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0042430 6 indole and derivative metabolism 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0009096 9,8,10 aromatic amino acid family biosynthesis, anthranilate pathway 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0009414 6,5 response to water deprivation 10 0,0015 1 0,0052 0,2278203 E GON7 GO:0001300 6,5 chronological cell aging 10 0,0015 1 0,0052 0,2278203 E SCH9 GO:0009415 5 response to water 10 0,0015 1 0,0052 0,2278203 E GON7 GO:0042435 8,6 indole derivative biosynthesis 10 0,0015 1 0,0052 0,2278203 E TRP5 GO:0007068 9,1 negative regulation of transcription, mitotic 10 0,0015 1 0,0052 0,2278203 E TFB4 GO:0006643 6,7 membrane lipid metabolism 106 0,0164 3 0,0155 0,2279563 D ARV1,MCD4,GAB1 GO:0050801 4 ion homeostasis 102 0,0158 3 0,0155 0,2290934 D CKA2,TRK1,ATX2 GO:0006873 5 cell ion homeostasis 98 0,0152 3 0,0155 0,2291364 E CKA2,TRK1,ATX2 GO:0007051 9 spindle organization and biogenesis 43 0,0067 2 0,0104 0,2334467 E HCM1,TUB4 GO:0006650 8,9 glycerophospholipid metabolism 46 0,0071 2 0,0104 0,2443588 E MCD4,GAB1 GO:0006626 10,8,9 protein targeting to mitochondrion 47 0,0073 2 0,0104 0,247612 E TIM50,MRS11 GO:0006812 6,7 cation transport 89 0,0138 2 0,0104 0,2505828 D MID1,FRE1 GO:0030003 6 cation homeostasis 89 0,0138 2 0,0104 0,2505828 D TRK1,ATX2 GO:0015837 5,6 amine transport 48 0,0074 2 0,0104 0,2506752 E VBA1,BAP3 GO:0007124 4 pseudohyphal growth 48 0,0074 2 0,0104 0,2506752 E FKH2,FKH1 GO:0007034 8,6,7 vacuolar transport 48 0,0074 2 0,0104 0,2506752 E VPS53,CCZ1 GO:0046942 6,7 carboxylic acid transport 50 0,0077 2 0,0104 0,2562387 E VBA1,BAP3 GO:0008361 6,5 regulation of cell size 12 0,0019 1 0,0052 0,2573347 E SCH9 GO:0006045 9,1 N-acetylglucosamine biosynthesis 12 0,0019 1 0,0052 0,2573347 E GNA1 GO:0006730 5 one-carbon compound metabolism 12 0,0019 1 0,0052 0,2573347 E MET7 GO:0000741 7 karyogamy 12 0,0019 1 0,0052 0,2573347 E KAR4 GO:0006042 8,9 glucosamine biosynthesis 12 0,0019 1 0,0052 0,2573347 E GNA1 GO:0000083 8,1 G1/S-specific transcription in mitotic cell cycle 12 0,0019 1 0,0052 0,2573347 E HCM1 GO:0046349 7,8 amino sugar biosynthesis 12 0,0019 1 0,0052 0,2573347 E GNA1 GO:0015849 5,6 organic acid transport 51 0,0079 2 0,0104 0,2587431 E VBA1,BAP3 GO:0015674 7,8 di-, tri-valent inorganic cation transport 51 0,0079 2 0,0104 0,2587431 E MID1,FRE1 GO:0016567 9 protein ubiquitination 51 0,0079 2 0,0104 0,2587431 E MET30,UBC1 GO:0042257 8,9 ribosomal subunit assembly 52 0,0081 2 0,0104 0,2610659 E RRP7,DBP7 GO:0008654 8,7,9 phospholipid biosynthesis 52 0,0081 2 0,0104 0,2610659 E MCD4,GAB1 GO:0000749 7,5 response to pheromone during conjugation with cellular fusion 53 0,0082 2 0,0104 0,2632096 E CBK1,PTP3 GO:0006644 7,8 phospholipid metabolism 79 0,0122 2 0,0104 0,267302 D MCD4,GAB1 GO:0030001 7,8 metal ion transport 57 0,0088 2 0,0104 0,2700523 E MID1,FRE1 GO:0009108 7 coenzyme biosynthesis 57 0,0088 2 0,0104 0,2700523 E ECM31,LIP5 GO:0007157 6 heterophilic cell adhesion 13 0,002 1 0,0052 0,2704704 E CKA2 GO:0006825 9,1 copper ion transport 13 0,002 1 0,0052 0,2704704 E FRE1 GO:0006267 9 pre-replicative complex formation and maintenance 13 0,002 1 0,0052 0,2704704 E CDC47 GO:0015893 5,6,7 drug transport 13 0,002 1 0,0052 0,2704704 E QDR3 GO:0007007 7,8 inner mitochondrial membrane organization and biogenesis 13 0,002 1 0,0052 0,2704704 E MRS11 GO:0000028 9,1 ribosomal small subunit assembly and maintenance 13 0,002 1 0,0052 0,2704704 E RRP7 GO:0006944 3 membrane fusion 58 0,009 2 0,0104 0,2713459 E YIP1,TLG2 GO:0006970 5 response to osmotic stress 59 0,0091 2 0,0104 0,2724795 E HOT1,BUD6 GO:0006623 10,8,9 protein targeting to vacuole 59 0,0091 2 0,0104 0,2724795 E VPS75,CCZ1 GO:0006875 7 metal ion homeostasis 60 0,0093 2 0,0104 0,2734565 E TRK1,ATX2 GO:0019236 6 response to pheromone 73 0,0113 2 0,0104 0,2736251 D CBK1,PTP3 GO:0046467 7,6,8 membrane lipid biosynthesis 71 0,011 2 0,0104 0,2749457 D MCD4,GAB1 GO:0007015 9 actin filament organization 63 0,0098 2 0,0104 0,2754853 E RDI1,BUD6 GO:0006897 6,7 endocytosis 69 0,0107 2 0,0104 0,2758227 D AKL1,UBC1 GO:0006512 8 ubiquitin cycle 69 0,0107 2 0,0104 0,2758227 D MET30,UBC1 GO:0042255 7,8 ribosome assembly 64 0,0099 2 0,0104 0,2758732 E RRP7,DBP7 GO:0006457 7 protein folding 67 0,0104 2 0,0104 0,2762255 D CCT8,CCT7 GO:0006044 8,9 N-acetylglucosamine metabolism 14 0,0022 1 0,0052 0,2825932 E GNA1 GO:0048278 6,7 vesicle docking 14 0,0022 1 0,0052 0,2825932 E CCZ1 GO:0000114 8,1 G1-specific transcription in mitotic cell cycle 14 0,0022 1 0,0052 0,2825932 E TAF6 GO:0006388 10,9 tRNA splicing 14 0,0022 1 0,0052 0,2825932 E NUP145 GO:0000079 6 regulation of cyclin dependent protein kinase activity 14 0,0022 1 0,0052 0,2825932 E CLB5 GO:0006041 7,8 glucosamine metabolism 14 0,0022 1 0,0052 0,2825932 E GNA1 GO:0009076 8,9 histidine family amino acid biosynthesis 14 0,0022 1 0,0052 0,2825932 E HIS7 GO:0006779 7 porphyrin biosynthesis 14 0,0022 1 0,0052 0,2825932 E HEM1 GO:0006783 8,7 heme biosynthesis 14 0,0022 1 0,0052 0,2825932 E HEM1 GO:0006547 8,9 histidine metabolism 14 0,0022 1 0,0052 0,2825932 E HIS7 GO:0000394 9 RNA splicing, via endonucleolytic cleavage and ligation 14 0,0022 1 0,0052 0,2825932 E NUP145 GO:0009075 7,8 histidine family amino acid metabolism 14 0,0022 1 0,0052 0,2825932 E HIS7 GO:0006040 6,7 amino sugar metabolism 14 0,0022 1 0,0052 0,2825932 E GNA1 GO:0016337 5 cell-cell adhesion 14 0,0022 1 0,0052 0,2825932 E CKA2 GO:0046148 6 pigment biosynthesis 14 0,0022 1 0,0052 0,2825932 E HEM1 GO:0000105 9,1 histidine biosynthesis 14 0,0022 1 0,0052 0,2825932 E HIS7 GO:0016051 7,6 carbohydrate biosynthesis 63 0,0098 1 0,0052 0,2869638 D GNA1 GO:0000011 7 vacuole inheritance 15 0,0023 1 0,0052 0,2937515 E VAC17 GO:0042440 5 pigment metabolism 15 0,0023 1 0,0052 0,2937515 E HEM1 GO:0006778 6 porphyrin metabolism 15 0,0023 1 0,0052 0,2937515 E HEM1 GO:0042168 7,6 heme metabolism 15 0,0023 1 0,0052 0,2937515 E HEM1 GO:0006625 10,7,8,9 protein targeting to peroxisome 15 0,0023 1 0,0052 0,2937515 E PEX15 GO:0016569 10 covalent chromatin modification 59 0,0091 1 0,0052 0,3036032 D TAF6 GO:0016570 11,8 histone modification 59 0,0091 1 0,0052 0,3036032 D TAF6 GO:0000054 11,8,9,10 ribosome export from nucleus 16 0,0025 1 0,0052 0,3039918 E NOG1 GO:0007265 7 Ras protein signal transduction 16 0,0025 1 0,0052 0,3039918 E MSI1 GO:0000753 7,8,6 cellular morphogenesis during conjugation with cellular fusion 16 0,0025 1 0,0052 0,3039918 E CBK1 GO:0010038 7 response to metal ion 16 0,0025 1 0,0052 0,3039918 E MET30 GO:0006493 10,9 protein amino acid O-linked glycosylation 16 0,0025 1 0,0052 0,3039918 E PMT1 GO:0009127 8,9 purine nucleoside monophosphate biosynthesis 16 0,0025 1 0,0052 0,3039918 E HIS7 GO:0000165 7 MAPKKK cascade 17 0,0026 1 0,0052 0,3133587 E PTP3 GO:0031570 7 DNA integrity checkpoint 17 0,0026 1 0,0052 0,3133587 E CSM3 GO:0009124 7,8 nucleoside monophosphate biosynthesis 17 0,0026 1 0,0052 0,3133587 E HIS7 GO:0009408 6,5 response to heat 17 0,0026 1 0,0052 0,3133587 E WSC2 GO:0009165 6,7 nucleotide biosynthesis 55 0,0085 1 0,0052 0,3197062 D HIS7 GO:0006896 10,9,8,7 Golgi to vacuole transport 18 0,0028 1 0,0052 0,3218951 E VPS53 GO:0009126 8 purine nucleoside monophosphate metabolism 18 0,0028 1 0,0052 0,3218951 E HIS7 GO:0007155 4 cell adhesion 18 0,0028 1 0,0052 0,3218951 E CKA2 GO:0019748 4 secondary metabolism 18 0,0028 1 0,0052 0,3218951 E HEM1 GO:0000767 6,5 cellular morphogenesis during conjugation 18 0,0028 1 0,0052 0,3218951 E CBK1 GO:0044264 6,7 cellular polysaccharide metabolism 53 0,0082 1 0,0052 0,3274302 D EXG1 GO:0005976 6 polysaccharide metabolism 53 0,0082 1 0,0052 0,3274302 D EXG1 GO:0007096 9,7 regulation of exit from mitosis 19 0,0029 1 0,0052 0,3296418 E CBK1 GO:0007006 6,7 mitochondrial membrane organization and biogenesis 19 0,0029 1 0,0052 0,3296418 E MRS11 GO:0000209 10 protein polyubiquitination 19 0,0029 1 0,0052 0,3296418 E UBC1 GO:0006081 5 aldehyde metabolism 19 0,0029 1 0,0052 0,3296418 E AAD3 GO:0006826 9,1 iron ion transport 19 0,0029 1 0,0052 0,3296418 E FRE1 GO:0042401 7,8 biogenic amine biosynthesis 19 0,0029 1 0,0052 0,3296418 E TRP5 GO:0000725 8,7 recombinational repair 19 0,0029 1 0,0052 0,3296418 E PDS1 GO:0009123 7 nucleoside monophosphate metabolism 19 0,0029 1 0,0052 0,3296418 E HIS7 GO:0030005 7 di-, tri-valent inorganic cation homeostasis 52 0,0081 1 0,0052 0,3311847 D ATX2 GO:0006892 9,7,6,8 post-Golgi transport 51 0,0079 1 0,0052 0,3348567 D VPS53 GO:0010035 6 response to inorganic substance 20 0,0031 1 0,0052 0,3366383 E MET30 GO:0040020 8 regulation of meiosis 20 0,0031 1 0,0052 0,3366383 E WTM2 GO:0042398 7,6 amino acid derivative biosynthesis 20 0,0031 1 0,0052 0,3366383 E TRP5 GO:0000288 9,1 mRNA catabolism, deadenylylation-dependent decay 20 0,0031 1 0,0052 0,3366383 E PUF4 GO:0006084 7 acetyl-CoA metabolism 20 0,0031 1 0,0052 0,3366383 E ACS2 GO:0006869 5,6 lipid transport 20 0,0031 1 0,0052 0,3366383 E ARV1 GO:0051052 7 regulation of DNA metabolism 21 0,0033 1 0,0052 0,3429221 E MGS1 GO:0031577 7 spindle checkpoint 21 0,0033 1 0,0052 0,3429221 E IBD2 GO:0007094 10,8 mitotic spindle checkpoint 21 0,0033 1 0,0052 0,3429221 E IBD2 GO:0030150 11,9,7,10,8 protein import into mitochondrial matrix 21 0,0033 1 0,0052 0,3429221 E TIM50 GO:0006413 9,8 translational initiation 48 0,0074 1 0,0052 0,3452895 D DED1 GO:0045944 10 positive regulation of transcription from RNA polymerase II promoter 48 0,0074 1 0,0052 0,3452895 D KAR4 GO:0043487 8 regulation of RNA stability 22 0,0034 1 0,0052 0,3485295 E PUF4 GO:0000750 7,8,6 signal transduction during conjugation with cellular fusion 22 0,0034 1 0,0052 0,3485295 E PTP3 GO:0043488 9,8 regulation of mRNA stability 22 0,0034 1 0,0052 0,3485295 E PUF4 GO:0006513 10 protein monoubiquitination 22 0,0034 1 0,0052 0,3485295 E UBC1 GO:0007093 9,7 mitotic checkpoint 22 0,0034 1 0,0052 0,3485295 E IBD2 GO:0006368 9 RNA elongation from RNA polymerase II promoter 22 0,0034 1 0,0052 0,3485295 E DST1 GO:0046916 8 transition metal ion homeostasis 47 0,0073 1 0,0052 0,3485408 D ATX2 GO:0030490 9 processing of 20S pre-rRNA 46 0,0071 1 0,0052 0,3516617 D BUD21 GO:0051246 6,5 regulation of protein metabolism 46 0,0071 1 0,0052 0,3516617 D NAM7 GO:0009889 5 regulation of biosynthesis 46 0,0071 1 0,0052 0,3516617 D NAM7 GO:0043161 11,12 proteasomal ubiquitin-dependent protein catabolism 46 0,0071 1 0,0052 0,3516617 D MET30 GO:0006163 7 purine nucleotide metabolism 46 0,0071 1 0,0052 0,3516617 D HIS7 GO:0031326 6 regulation of cellular biosynthesis 46 0,0071 1 0,0052 0,3516617 D NAM7 GO:0006354 8 RNA elongation 23 0,0036 1 0,0052 0,3534949 E DST1 GO:0006752 7 group transfer coenzyme metabolism 44 0,0068 1 0,0052 0,3574676 D ECM31 GO:0030472 9,11,5 mitotic spindle organization and biogenesis in nucleus 24 0,0037 1 0,0052 0,3578517 E TUB4 GO:0051252 7 regulation of RNA metabolism 24 0,0037 1 0,0052 0,3578517 E PUF4 GO:0000041 8,9 transition metal ion transport 43 0,0067 1 0,0052 0,3601286 D FRE1 GO:0009064 7,8 glutamine family amino acid metabolism 43 0,0067 1 0,0052 0,3601286 D PRO3 GO:0006164 7,8 purine nucleotide biosynthesis 43 0,0067 1 0,0052 0,3601286 D HIS7 GO:0006576 6,7 biogenic amine metabolism 25 0,0039 1 0,0052 0,3616315 E TRP5 GO:0006270 9 DNA replication initiation 25 0,0039 1 0,0052 0,3616315 E CDC47 GO:0007052 8,1 mitotic spindle organization and biogenesis 42 0,0065 1 0,0052 0,3626116 D TUB4 GO:0000122 10 negative regulation of transcription from RNA polymerase II promoter 41 0,0064 1 0,0052 0,3649028 D TFB4 GO:0006302 8,7 double-strand break repair 41 0,0064 1 0,0052 0,3649028 D RFA2 GO:0006575 6 amino acid derivative metabolism 27 0,0042 1 0,0052 0,3675806 E TRP5 GO:0009605 4 response to external stimulus 27 0,0042 1 0,0052 0,3675806 E SKI8 GO:0007186 6 G-protein coupled receptor protein signaling pathway 27 0,0042 1 0,0052 0,3675806 E PTP3 GO:0000027 9,1 ribosomal large subunit assembly and maintenance 39 0,006 1 0,0052 0,3688534 D DBP7 GO:0007033 6 vacuole organization and biogenesis 39 0,006 1 0,0052 0,3688534 D VAC17 GO:0006073 7,8 glucan metabolism 39 0,006 1 0,0052 0,3688534 D EXG1 GO:0016573 12,9 histone acetylation 28 0,0043 1 0,0052 0,3698069 E TAF6 GO:0048308 6 organelle inheritance 38 0,0059 1 0,0052 0,3704824 D VAC17 GO:0006445 9,8,7 regulation of translation 29 0,0045 1 0,0052 0,3715703 E NAM7 GO:0006665 7,8 sphingolipid metabolism 29 0,0045 1 0,0052 0,3715703 E ARV1 GO:0006417 8,7,6 regulation of protein biosynthesis 30 0,0046 1 0,0052 0,3728965 E NAM7 GO:0007032 6 endosome organization and biogenesis 36 0,0056 1 0,0052 0,3729664 D VPS53 GO:0016197 8,7,6 endosome transport 36 0,0056 1 0,0052 0,3729664 D VPS53 GO:0006887 6,7 exocytosis 36 0,0056 1 0,0052 0,3729664 D YPT31 GO:0006914 4 autophagy 36 0,0056 1 0,0052 0,3729664 D CCZ1 GO:0042493 6 response to drug 31 0,0048 1 0,0052 0,3738098 E QDR3 GO:0008643 5,6 carbohydrate transport 34 0,0053 1 0,0052 0,3743011 D HUT1 GO:0008033 8 tRNA processing 34 0,0053 1 0,0052 0,3743011 D NUP145 GO:0001403 4 invasive growth (sensu Saccharomyces) 32 0,005 1 0,0052 0,3743335 E KSS1 GO:0030004 7 monovalent inorganic cation homeostasis 32 0,005 1 0,0052 0,3743335 E TRK1 GO:0008150 1 biological_process 6454 1 193 1 1 D RRN3,TYR1,RDI1,PNP1,FMP32,COG2,POL2,TOS2,LOT6,KTR7,KAR4,YCS4,ARO7,VAC17,CKA2,SRP68,RGR1,FKH2,CDC11,NAT5,RNH201,RFA2,SPT21,ELP4,SMX3,HCM1,FYV4,NAT2,ARV1,BUD21,NAR1,TUP1,VPS75,STT3,TIM50,PGD1,DCG1,GIN4,DST1,FMP38,TRS20,PDS5,SRL1,HMT1,RRP7,HSL7,SKI8,NOG1,HSH155,BBP1,YIP1,RSM24,ERG12,HIS7,PML39,COG1,CSM1,RPB2,MNN11,MSH1,KSS1,SLN1,BUD16,TAO3,TAF6,SEY1,AAD3,TRK1,ERG6,CAF4,GON7,CCT8,DBP7,PEX15,POL30,HOT1,VPS53,SRP54,ALG14,MXR1,TUB4,POM34,THG1,MRS11,SPL2,SRP21,IBD2,WSC2,RFC2,SNF12,PPS1,TLG2,SIT4,AKL1,MNN9,MCD4,MET7,NGL2,ERG26,SMD1,CSM3,SCH9,GAB1,PRP19,SAN1,ARO3,HEM1,SUB2,VBA1,EXG1,PDS1,BNI5,MET30,PMT1,ILV6,ATX2,NDC1,YSH1,HUT1,IKI1,SLY1,CLB5,SPC25,OPY1,TBF1,KAE1,WTM2,IFH1,CKS1,PEX31,TRM11,ACS2,YEH2,BFR1,CDC47,NUP100,DIB1,NMT1,UBC1,PUS1,CBK1,TRP5,ECM31,NAM7,RRP42,UIP5,MID1,QDR3,CDC50,BAP3,BUD6,PUF4,RRP43,HSL1,AGE2,NUP133,PFA5,FRE1,NUP145,GCD14,FKH1,YPT31,RSR1,MGS1,LEU3,LSM5,PTP3,PRO3,DED1,FIP1,ARL3,MSI1,KIN4,YPS7,GNA1,PCL2,UTP22,TFB4,GRX4,LIP5,DDP1,KTR6,PHS1,CCA1,CCZ1,OAZ1,MEI4,CCT7,CTF18,MUD2,HUR1,ERP1,DPH1