GO_ID LEVEL(S) TERM NB_IN_REF FREQ_IN_REF NB_IN_SET FREQ_IN_SET P_VALUE ENRICHMENT/DEPLETION GENES_IN_SET GO:0000004 2 biological process unknown 1639 0,254 93 0,1165 9,99E-22 D YCP4,PNS1,NAB6,BDF2,FMP16,YPT35,UIP4,PTC7,MTQ1,COS1,RFS1,FMP33,NUS1,SPG4,COS2,ZSP1,RTN2,CPR8,PSP1,SPG3,ERJ5,UIP3,BCH1,NPC2,JIP4,ARP8,FMP13,TCB1,KRE29,AST2,YPS6,FMP22,OMS1,CTS2,YPS5,ZRG8,CUE3,BOP2,NIT1,HSP31,VAB2,SYP1,FMP12,AFG1,UGX2,ERR1,FMP30,LDB17,YET1,LEE1,STB3,HSV2,OM45,PTC5,ZTA1,FMP14,NSG2,QRI5,YHI9,YET3,UBP11,COS4,FMP21,UBX3,LSB1,PAU7,FMP46,DCS2,PTM1,MCX1,CUE5,PHM8,TRE2,FUN19,FMP37,MDR1,FMP29,YEN1,FRE5,UTR4,REH1,FMP10,CAJ1,MPM1,GTO3,YJU3,RCR2,SHE10,TVP18,DSE3,COS6,FMP34,TMT1 GO:0006091 5 generation of precursor metabolites and energy 224 0,0347 86 0,1078 3,03E-21 E PFK26,SDH2,TDH3,ZWF1,LSC1,ADH2,TAZ1,SHP1,FYV10,GLC3,COX14,MRPL1,ACS1,QCR8,RMD5,ATP2,COX6,STF2,ATP5,NTH2,MCR1,TDH2,TKL2,PFK27,MDH1,KGD1,PCL6,QCR10,GLC8,COQ9,MCT1,NDI1,SOL4,VID30,GLG2,DLD1,CIT2,PPG1,ADE16,COX8,SDH1,CYB2,RIP1,QCR6,CIT3,GLG1,GPH1,SGA1,ETR1,UBC8,ENO1,IDP3,GPM1,TPS1,MBR1,TSL1,COR1,INH1,COX20,PCL7,ATP15,ENO2,QCR9,BMH2,CIT1,COX4,NTH1,YPI1,TPS3,ATP16,RSF1,GSY2,GID8,BMH1,KGD2,SDH3,QCR2,CYC7,ATP3,ATP17,MDH3,TDH1,GDB1,QCR7,SDH4,NDE1 GO:0007582 2 physiological process 4771 0,7392 698 0,8747 1,64E-20 E ASR1,SSA2,BDF1,GIP2,SCL1,PEX8,CBS2,TFG1,VPS29,MLC1,ZIP1,SAC6,PGM2,GYP7,MEF2,ISA2,ADR1,WHI5,ARC40,ATG4,SIP2,MAL13,PFK26,SIP18,SNF3,SRL3,AMA1,SAP155,SDH2,BUB3,USA1,ULA1,FRT2,TDH3,PRE7,UBR1,POG1,RPN11,ARO9,GLR1,YMR1,REC114,RPN7,RPD3,YVC1,SYM1,ZWF1,NPL3,ALD3,RPT1,HOR7,FYV6,APS1,LSC1,SHR5,ADH2,CNE1,PRP5,TAZ1,YPR1,MTM1,MED4,DOG2,ECM2,COQ6,KIN1,PEX2,COX15,SMY1,SHP1,MDJ1,HSP82,FYV10,ADY2,ALD6,LEO1,PUT1,SHE2,ARC35,GLC3,PUP2,AYR1,LSP1,COX14,YRR1,CMP2,MRPL1,RIB4,SIZ1,PPH22,PTH1,MDM31,SNX41,MLF3,ACS1,ARC15,RPB7,YPT1,PRE10,FIT2,NVJ1,HMX1,QCR8,HUA1,PHO2,SFT2,TAD3,SPT2,RPT2,RMD5,MSY1,SNC1,ATP2,STE18,COX6,FOX2,YIM1,STF2,PMP3,ECM21,SNF4,CNN1,YAF9,ATP5,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,HMO1,SSQ1,SIC1,LAG1,ECM18,RAD59,SCT1,PAP2,ATP10,PAI3,BET3,OSH6,OPY2,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SET3,UBX7,RIB5,SMF3,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,LAS17,ATG1,ERG9,SOD1,RAD2,RUP1,CRD1,NTA1,KIN2,HYS2,VPS60,MAL12,CSG2,EHT1,PCL6,ASK10,PPZ2,KNS1,ISU1,NPL4,ERV14,PDX1,QCR10,GUT1,ALG2,UBP15,KRE11,GLC8,PTK2,SSE1,COQ9,FAA1,DNM1,GND2,MTL1,CBP4,UFD1,MCT1,ARP3,GRR1,LAG2,BET4,SEC17,NDI1,STE11,ALD4,RPH1,MDG1,JEN1,PRB1,PEX3,COT1,YIP4,SIP5,GSF2,ADP1,SNU71,VPS73,AHA1,PRM5,XYL2,SOL4,SYN8,VID30,RPN9,UBP6,ISW1,VPS5,CST6,APL1,NPR1,AOS1,EST3,GLG2,MRPL28,UGA3,ECM4,ENA2,TPK1,PRX1,TCO89,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,NUD1,HXT6,HXT16,VAM6,STI1,DLD1,PRI1,GTS1,AQY1,PEX22,PEX25,RTG2,LRE1,CTT1,CIT2,PPG1,PMT2,PCL5,SWS2,YBP1,RIM21,BBC1,ATG9,NCE103,HXK1,MMS4,PEP12,APM2,SSE2,UFD2,ADE16,COX8,FMS1,MAG1,SDH1,RAD50,KRE9,CYB2,FMP45,MEC1,SCD5,TUS1,RIP1,QCR6,WHI4,CIT3,COS3,SDS22,GLG1,MRP20,GDH3,CCL1,GPH1,DAP2,CSE1,RPO41,BET5,SEC6,MSF1,KAR2,HXT5,PNC1,YME1,FAD1,ASP3-3,TAX4,SAM50,TOM6,MEX67,MPD1,IST1,INO4,CDC73,ECM10,MPS1,SGA1,NCE102,AHP1,BNA1,MSL5,PAN3,YRF1-2,FMT1,ATG17,YIP5,XBP1,FIT3,AVO2,TGL4,ETR1,IMP2prime,MYO4,CDC37,RIM11,UBC8,GGA1,CST9,SLG1,AVT3,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,VPS17,HMI1,TRA1,SEC9,XKS1,VAC8,IMP1,SEC10,GOS1,MCH1,HXT7,VTI1,DAP1,SET2,ENO1,PSK2,GEM1,MCM3,BCK2,SRY1,CPR6,PPM1,CUS2,PXA2,ERD2,IDP3,SLF1,GRX2,DOA1,ILS1,OAF1,VHS2,RGA2,TPK2,GPM1,SSK2,CAP2,HSP78,EPL1,HCH1,SCO2,PEX5,PHR1,PDH1,PXA1,RNY1,RHO3,SSA4,ACH1,TGL1,ENT5,APC9,CHA1,RAD1,HST3,FAR10,GTR2,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,MSB3,THP1,TPS1,BIO3,PTP2,TIM21,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,SNX4,TOR1,ECM32,GRE3,SIF2,MBR1,TSL1,ARP2,RCK2,GAL10,RSC9,IPK1,STR2,SSC1,MUB1,MSK1,PHO23,ARO80,MUP3,TPM2,DCS1,COR1,VPS38,YPT52,SNG1,PRP4,EXO70,YAP1801,RSE1,EXO1,THI21,VPS30,RAD52,INH1,GRX1,CAR2,KIN82,SPC105,PUP1,COX20,NGR1,CNB1,PRP12,RAD26,PCL7,RIM20,ATG7,BCY1,ALD2,PEX29,VPS52,NEM1,ATP15,APA1,SBE22,UBA3,EMI2,PET123,EAP1,DLD3,ENO2,SCP1,PEX19,AFR1,CAP1,YAP1,PAP1,AVO1,GLO4,AGX1,PRM8,ATG12,ENT1,MRP8,MRL1,DIT1,DAK2,THI3,RPN6,ATG19,VMR1,MYO3,PIC2,PEP8,RTG1,SWI5,HSC82,FIS1,QCR9,BMH2,TSC13,POP5,VPS15,TRP4,MRPL16,TPM1,PIL1,SEC12,DPP1,COQ4,ASP3-4,MDM34,MSR1,YOR1,OKP1,HSP26,HAP2,WTM1,CIT1,ADE8,AHC1,RSM18,MAL33,SEC15,PAF1,COX4,YPT7,ENT3,ECM30,TFS1,GPT2,AGP2,MUM2,MDM10,COQ3,NTH1,YMR31,IZH3,YDC1,STE5,YPI1,TPS3,GUT2,TRM12,CHL4,ATP16,MET22,RCY1,ECM14,CIN5,UBP2,PRP45,RSF1,ROT1,RIM4,PEX12,YKU80,MTR10,CYR1,HAP5,PFY1,YRM1,PYK2,GPX1,IQG1,BUL1,GSY2,MAD1,GID8,UBX6,GLK1,MRP51,GRE2,SSP120,DPL1,KTR4,ASM4,GCY1,BMH1,DIP5,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,CHO1,RAS2,SSA1,NUT2,PRE1,GAD1,RGT2,HEM15,MPT5,YKU70,AZF1,MRPL31,YTA7,ARO10,SNF5,FAR11,PUT3,HYP2,PEP1,YPK2,REH1,ARA1,HSM3,SDS24,YPC1,UBX5,CCP1,QCR2,CKI1,CYC7,LAP4,ARC19,RFA1,VPS70,CLN3,EMP46,SSD1,GLO2,VPS21,BOR1,LTP1,BSD2,MMM1,INO1,VPS45,NYV1,HXT13,SSO1,ATP3,RSM28,SEC28,CRM1,VPS8,ADE2,ATP17,VHS3,MDH3,TDH1,UGA2,CSR2,QRI8,PEP7,GPI19,PHB1,SKN1,PDX3,GDB1,TDP1,STE24,SPO14,ARG4,EDE1,RPN14,LSB5,GAL11,QCR7,APA2,SDH4,CLC1,NDE1,XRS2 GO:0005975 5 carbohydrate metabolism 219 0,0339 80 0,1003 5,30E-18 E PGM2,ADR1,MAL13,PFK26,SDH2,TDH3,ZWF1,LSC1,YPR1,DOG2,SHP1,FYV10,GLC3,RMD5,NTH2,TDH2,TKL2,PFK27,MDH1,KGD1,MAL12,PCL6,GLC8,GND2,XYL2,SOL4,VID30,GLG2,FBP26,DLD1,CIT2,PPG1,HXK1,SDH1,KRE9,CIT3,GLG1,GPH1,SGA1,IMP2prime,UBC8,XKS1,ENO1,PSK2,IDP3,GPM1,TPS1,GAL7,GRE3,TSL1,GAL10,IPK1,PCL7,ENO2,GLO4,BMH2,HAP2,CIT1,MAL33,NTH1,YPI1,TPS3,GUT2,HAP5,GSY2,GID8,GLK1,GCY1,BMH1,KGD2,UGP1,SDH3,ARA1,GLO2,INO1,MDH3,TDH1,SKN1,GDB1,SDH4 GO:0009987 2 cellular process 4682 0,7254 682 0,8546 1,35E-17 E SSA2,BDF1,GIP2,SCL1,PEX8,CBS2,TFG1,VPS29,MLC1,ZIP1,SAC6,PGM2,GYP7,MEF2,ISA2,ADR1,WHI5,ARC40,ATG4,SIP2,MAL13,PFK26,SNF3,SRL3,AMA1,SAP155,SDH2,BUB3,USA1,ULA1,TDH3,PRE7,UBR1,POG1,RPN11,ARO9,GLR1,YMR1,REC114,RPN7,RPD3,YVC1,SYM1,ZWF1,NPL3,ALD3,RPT1,FYV6,APS1,LSC1,SHR5,ADH2,CNE1,PRP5,TAZ1,YPR1,MTM1,MED4,DOG2,ECM2,COQ6,KIN1,PEX2,COX15,SMY1,SHP1,MDJ1,HSP82,FYV10,ADY2,ALD6,LEO1,PUT1,ARC35,GLC3,PUP2,AYR1,COX14,YRR1,CMP2,MRPL1,RIB4,SIZ1,PPH22,PTH1,MDM31,SNX41,ACS1,ARC15,RPB7,YPT1,PRE10,FIT2,NVJ1,HMX1,QCR8,HUA1,PHO2,SFT2,TAD3,SPT2,RPT2,RMD5,MSY1,SNC1,ATP2,STE18,COX6,FOX2,STF2,PMP3,ECM21,SNF4,CNN1,YAF9,ATP5,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,HMO1,SSQ1,SIC1,LAG1,ECM18,RAD59,SCT1,PAP2,ATP10,BET3,OSH6,OPY2,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SET3,UBX7,RIB5,SMF3,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,LAS17,ATG1,ERG9,SOD1,RAD2,RUP1,CRD1,NTA1,KIN2,HYS2,VPS60,MAL12,CSG2,PCL6,ASK10,PPZ2,KNS1,ISU1,NPL4,ERV14,PDX1,QCR10,GUT1,ALG2,UBP15,KRE11,GLC8,PTK2,SSE1,COQ9,FAA1,DNM1,GND2,MTL1,CBP4,UFD1,MCT1,ARP3,GRR1,LAG2,BET4,SEC17,NDI1,STE11,ALD4,RPH1,MDG1,JEN1,PRB1,PEX3,COT1,YIP4,SIP5,GSF2,ADP1,SNU71,VPS73,AHA1,PRM5,XYL2,SOL4,SYN8,VID30,RPN9,UBP6,ISW1,VPS5,CST6,APL1,AOS1,EST3,GLG2,MRPL28,UGA3,ECM4,ENA2,TPK1,PRX1,TCO89,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,NUD1,HXT6,HXT16,VAM6,STI1,DLD1,PRI1,GTS1,AQY1,PEX22,PEX25,RTG2,LRE1,CIT2,PPG1,PMT2,PCL5,SWS2,YBP1,RIM21,BBC1,ATG9,NCE103,HXK1,MMS4,PEP12,APM2,SSE2,UFD2,ADE16,COX8,FMS1,MAG1,SDH1,RAD50,KRE9,CYB2,FMP45,MEC1,SCD5,TUS1,RIP1,QCR6,WHI4,CIT3,COS3,SDS22,GLG1,MRP20,GPB2,GDH3,CCL1,GPH1,DAP2,CSE1,RPO41,BET5,SEC6,MSF1,KAR2,HXT5,PNC1,YME1,FAD1,ASP3-3,TAX4,SAM50,TOM6,MEX67,MPD1,IST1,INO4,CDC73,ECM10,MPS1,SGA1,AHP1,BNA1,MSL5,PAN3,YRF1-2,FMT1,ATG17,YIP5,FIT3,AVO2,TGL4,ETR1,IMP2prime,MYO4,CDC37,RIM11,UBC8,GGA1,CST9,SLG1,AVT3,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,VPS17,HMI1,TRA1,SEC9,XKS1,VAC8,IMP1,SEC10,GOS1,MCH1,HXT7,VTI1,DAP1,SET2,ENO1,PSK2,GEM1,MCM3,BCK2,SRY1,CPR6,PPM1,CUS2,PXA2,IDP3,SLF1,GRX2,DOA1,ILS1,OAF1,VHS2,RGA2,TPK2,GPM1,SSK2,CAP2,HSP78,PDE1,EPL1,HCH1,SCO2,PEX5,PHR1,PDH1,PXA1,RNY1,RHO3,SSA4,ACH1,TGL1,ENT5,APC9,COS111,CHA1,RAD1,HST3,FAR10,GTR2,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,MSB3,THP1,TPS1,BIO3,PTP2,TIM21,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,SNX4,TOR1,ECM32,GRE3,SIF2,MBR1,TSL1,ARP2,RCK2,GAL10,RSC9,IPK1,STR2,SSC1,MUB1,MSK1,PHO23,ARO80,MUP3,TPM2,DCS1,COR1,VPS38,YPT52,PRP4,EXO70,YAP1801,RSE1,LEM3,EXO1,THI21,VPS30,RAD52,INH1,GRX1,CAR2,KIN82,SPC105,PUP1,COX20,NGR1,CNB1,PRP12,RAD26,PCL7,RIM20,ATG7,BCY1,ALD2,PEX29,VPS52,NEM1,ATP15,APA1,SBE22,UBA3,EMI2,PET123,EAP1,DLD3,ENO2,SCP1,PEX19,AFR1,CAP1,YAP1,PAP1,AVO1,GLO4,AGX1,PRM8,ATG12,ENT1,MRP8,MRL1,DIT1,DAK2,THI3,RPN6,ATG19,VMR1,MYO3,PIC2,PEP8,RTG1,SWI5,HSC82,FIS1,QCR9,BMH2,TSC13,POP5,IRA2,VPS15,TRP4,MRPL16,TPM1,SEC12,DPP1,COQ4,ASP3-4,MDM34,MSR1,YOR1,OKP1,HSP26,HAP2,WTM1,CIT1,ADE8,AHC1,RSM18,MAL33,SEC15,PAF1,COX4,YPT7,ENT3,ECM30,TFS1,GPT2,AGP2,MUM2,MDM10,COQ3,NTH1,YMR31,IZH3,YDC1,STE5,YPI1,TPS3,GUT2,TRM12,CHL4,ATP16,MET22,RCY1,ECM14,CIN5,UBP2,PRP45,RSF1,ROT1,RIM4,PEX12,YKU80,MTR10,CYR1,HAP5,PFY1,YRM1,PYK2,GPX1,IQG1,BUL1,GSY2,MAD1,GID8,UBX6,GLK1,MRP51,DPL1,KTR4,ASM4,GCY1,BMH1,DIP5,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,CHO1,RAS2,SSA1,BAG7,NUT2,PRE1,GAD1,RGT2,HEM15,MPT5,YKU70,AZF1,MRPL31,ARO10,SNF5,FAR11,PUT3,HYP2,PEP1,YPK2,REH1,HSM3,SDS24,YPC1,UBX5,CCP1,QCR2,CKI1,CYC7,ARC19,RFA1,VPS70,CLN3,EMP46,SSD1,GLO2,VPS21,BOR1,LTP1,BSD2,MMM1,INO1,VPS45,NYV1,HXT13,SSO1,ATP3,RSM28,SEC28,CRM1,VPS8,ADE2,ATP17,VHS3,MDH3,TDH1,UGA2,CSR2,QRI8,PEP7,GPI19,PHB1,SKN1,PDX3,GDB1,TDP1,STE24,SPO14,ARG4,EDE1,RPN14,LSB5,GAL11,QCR7,APA2,SDH4,CLC1,NDE1,XRS2 GO:0015980 6 energy derivation by oxidation of organic compounds 194 0,0301 73 0,0915 4,27E-17 E PFK26,SDH2,TDH3,ZWF1,LSC1,ADH2,SHP1,FYV10,GLC3,COX14,MRPL1,ACS1,QCR8,RMD5,COX6,NTH2,TDH2,TKL2,PFK27,MDH1,KGD1,PCL6,QCR10,GLC8,COQ9,MCT1,SOL4,VID30,GLG2,DLD1,CIT2,PPG1,ADE16,COX8,SDH1,RIP1,QCR6,CIT3,GLG1,GPH1,SGA1,ETR1,UBC8,ENO1,IDP3,GPM1,TPS1,MBR1,TSL1,COR1,COX20,PCL7,ENO2,QCR9,BMH2,CIT1,COX4,NTH1,YPI1,TPS3,RSF1,GSY2,GID8,BMH1,KGD2,SDH3,QCR2,MDH3,TDH1,GDB1,QCR7,SDH4,NDE1 GO:0050875 3 cellular physiological process 4641 0,7191 673 0,8434 8,25E-16 E SSA2,BDF1,GIP2,SCL1,PEX8,CBS2,TFG1,VPS29,MLC1,ZIP1,SAC6,PGM2,GYP7,MEF2,ISA2,ADR1,WHI5,ARC40,ATG4,SIP2,MAL13,PFK26,SRL3,AMA1,SAP155,SDH2,BUB3,USA1,ULA1,TDH3,PRE7,UBR1,POG1,RPN11,ARO9,GLR1,YMR1,REC114,RPN7,RPD3,YVC1,SYM1,ZWF1,NPL3,ALD3,RPT1,FYV6,APS1,LSC1,SHR5,ADH2,CNE1,PRP5,TAZ1,YPR1,MTM1,MED4,DOG2,ECM2,COQ6,KIN1,PEX2,COX15,SMY1,SHP1,MDJ1,HSP82,FYV10,ADY2,ALD6,LEO1,PUT1,ARC35,GLC3,PUP2,AYR1,COX14,YRR1,CMP2,MRPL1,RIB4,SIZ1,PPH22,PTH1,MDM31,SNX41,ACS1,ARC15,RPB7,YPT1,PRE10,FIT2,NVJ1,HMX1,QCR8,HUA1,PHO2,SFT2,TAD3,SPT2,RPT2,RMD5,MSY1,SNC1,ATP2,STE18,COX6,FOX2,STF2,PMP3,ECM21,SNF4,CNN1,YAF9,ATP5,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,HMO1,SSQ1,SIC1,LAG1,ECM18,RAD59,SCT1,PAP2,ATP10,BET3,OSH6,OPY2,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SET3,UBX7,RIB5,SMF3,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,LAS17,ATG1,ERG9,SOD1,RAD2,RUP1,CRD1,NTA1,KIN2,HYS2,VPS60,MAL12,CSG2,PCL6,ASK10,PPZ2,KNS1,ISU1,NPL4,ERV14,PDX1,QCR10,GUT1,ALG2,UBP15,KRE11,GLC8,PTK2,SSE1,COQ9,FAA1,DNM1,GND2,MTL1,CBP4,UFD1,MCT1,ARP3,GRR1,LAG2,BET4,SEC17,NDI1,STE11,ALD4,RPH1,MDG1,JEN1,PRB1,PEX3,COT1,YIP4,SIP5,GSF2,ADP1,SNU71,VPS73,AHA1,PRM5,XYL2,SOL4,SYN8,VID30,RPN9,UBP6,ISW1,VPS5,CST6,APL1,AOS1,EST3,GLG2,MRPL28,UGA3,ECM4,ENA2,TPK1,PRX1,TCO89,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,NUD1,HXT6,HXT16,VAM6,STI1,DLD1,PRI1,GTS1,AQY1,PEX22,PEX25,RTG2,LRE1,CIT2,PPG1,PMT2,PCL5,SWS2,YBP1,RIM21,BBC1,ATG9,NCE103,HXK1,MMS4,PEP12,APM2,SSE2,UFD2,ADE16,COX8,FMS1,MAG1,SDH1,RAD50,KRE9,CYB2,FMP45,MEC1,SCD5,TUS1,RIP1,QCR6,WHI4,CIT3,COS3,SDS22,GLG1,MRP20,GDH3,CCL1,GPH1,DAP2,CSE1,RPO41,BET5,SEC6,MSF1,KAR2,HXT5,PNC1,YME1,FAD1,ASP3-3,TAX4,SAM50,TOM6,MEX67,MPD1,IST1,INO4,CDC73,ECM10,MPS1,SGA1,AHP1,BNA1,MSL5,PAN3,YRF1-2,FMT1,ATG17,YIP5,FIT3,AVO2,TGL4,ETR1,IMP2prime,MYO4,CDC37,RIM11,UBC8,GGA1,CST9,SLG1,AVT3,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,VPS17,HMI1,TRA1,SEC9,XKS1,VAC8,IMP1,SEC10,GOS1,MCH1,HXT7,VTI1,DAP1,SET2,ENO1,PSK2,GEM1,MCM3,BCK2,SRY1,CPR6,PPM1,CUS2,PXA2,IDP3,SLF1,GRX2,DOA1,ILS1,OAF1,VHS2,RGA2,TPK2,GPM1,SSK2,CAP2,HSP78,EPL1,HCH1,SCO2,PEX5,PHR1,PDH1,PXA1,RNY1,RHO3,SSA4,ACH1,TGL1,ENT5,APC9,CHA1,RAD1,HST3,FAR10,GTR2,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,MSB3,THP1,TPS1,BIO3,PTP2,TIM21,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,SNX4,TOR1,ECM32,GRE3,SIF2,MBR1,TSL1,ARP2,RCK2,GAL10,RSC9,IPK1,STR2,SSC1,MUB1,MSK1,PHO23,ARO80,MUP3,TPM2,DCS1,COR1,VPS38,YPT52,PRP4,EXO70,YAP1801,RSE1,EXO1,THI21,VPS30,RAD52,INH1,GRX1,CAR2,KIN82,SPC105,PUP1,COX20,NGR1,CNB1,PRP12,RAD26,PCL7,RIM20,ATG7,ALD2,PEX29,VPS52,NEM1,ATP15,APA1,SBE22,UBA3,EMI2,PET123,EAP1,DLD3,ENO2,SCP1,PEX19,AFR1,CAP1,YAP1,PAP1,AVO1,GLO4,AGX1,PRM8,ATG12,ENT1,MRP8,MRL1,DIT1,DAK2,THI3,RPN6,ATG19,VMR1,MYO3,PIC2,PEP8,RTG1,SWI5,HSC82,FIS1,QCR9,BMH2,TSC13,POP5,VPS15,TRP4,MRPL16,TPM1,SEC12,DPP1,COQ4,ASP3-4,MDM34,MSR1,YOR1,OKP1,HSP26,HAP2,WTM1,CIT1,ADE8,AHC1,RSM18,MAL33,SEC15,PAF1,COX4,YPT7,ENT3,ECM30,TFS1,GPT2,AGP2,MUM2,MDM10,COQ3,NTH1,YMR31,IZH3,YDC1,STE5,YPI1,TPS3,GUT2,TRM12,CHL4,ATP16,MET22,RCY1,ECM14,CIN5,UBP2,PRP45,RSF1,ROT1,RIM4,PEX12,YKU80,MTR10,CYR1,HAP5,PFY1,YRM1,PYK2,GPX1,IQG1,BUL1,GSY2,MAD1,GID8,UBX6,GLK1,MRP51,DPL1,KTR4,ASM4,GCY1,BMH1,DIP5,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,CHO1,RAS2,SSA1,NUT2,PRE1,GAD1,HEM15,MPT5,YKU70,AZF1,MRPL31,ARO10,SNF5,FAR11,PUT3,HYP2,PEP1,YPK2,REH1,HSM3,SDS24,YPC1,UBX5,CCP1,QCR2,CKI1,CYC7,ARC19,RFA1,VPS70,CLN3,EMP46,SSD1,GLO2,VPS21,BOR1,LTP1,BSD2,MMM1,INO1,VPS45,NYV1,HXT13,SSO1,ATP3,RSM28,SEC28,CRM1,VPS8,ADE2,ATP17,VHS3,MDH3,TDH1,UGA2,CSR2,QRI8,PEP7,GPI19,PHB1,SKN1,PDX3,GDB1,TDP1,STE24,SPO14,ARG4,EDE1,RPN14,LSB5,GAL11,QCR7,APA2,SDH4,CLC1,NDE1,XRS2 GO:0006414 9,8 translational elongation 312 0,0483 1 0,0013 2,21E-14 D MEF2 GO:0044262 6 cellular carbohydrate metabolism 201 0,0311 69 0,0865 1,35E-13 E PGM2,PFK26,SDH2,TDH3,ZWF1,LSC1,YPR1,DOG2,SHP1,FYV10,GLC3,RMD5,NTH2,TDH2,TKL2,PFK27,MDH1,KGD1,MAL12,PCL6,GLC8,GND2,XYL2,SOL4,VID30,GLG2,FBP26,CIT2,PPG1,HXK1,SDH1,KRE9,CIT3,GLG1,GPH1,SGA1,UBC8,XKS1,ENO1,PSK2,IDP3,GPM1,TPS1,GAL7,GRE3,TSL1,GAL10,IPK1,PCL7,ENO2,BMH2,CIT1,NTH1,YPI1,TPS3,GSY2,GID8,GLK1,GCY1,BMH1,KGD2,UGP1,SDH3,INO1,MDH3,TDH1,SKN1,GDB1,SDH4 GO:0050896 3 response to stimulus 549 0,0851 134 0,1679 1,64E-13 E ASR1,BDF1,SAC6,SIP2,SIP18,SNF3,FRT2,POG1,GLR1,RPD3,ZWF1,ALD3,HOR7,FYV6,DOG2,HSP82,PUP2,LSP1,YRR1,CMP2,MLF3,PHO2,STE18,YIM1,STF2,NTH2,RAD59,OPY2,DDR48,UBC4,MCR1,AIP1,LAS17,SOD1,RAD2,HYS2,ASK10,GRR1,STE11,RPH1,MDG1,PRB1,SIP5,AHA1,RAD18,GTS1,LRE1,CTT1,YBP1,NCE103,MMS4,UFD2,MAG1,RAD50,MEC1,KAR2,ASP3-3,AHP1,PAN3,XBP1,IMP2prime,RIM11,SLG1,HSP104,GRX2,DOA1,RGA2,SSK2,HSP78,HCH1,PHR1,SSA4,RAD1,FAR10,SSA3,UBI4,TPS1,PTP2,MRK1,POS5,RAD6,GRE3,TSL1,SNG1,EXO1,RAD52,GRX1,KIN82,CNB1,RAD26,BCY1,AFR1,YAP1,GLO4,DAK2,MYO3,HSC82,BMH2,PIL1,ASP3-4,YOR1,HSP26,AGP2,NTH1,YDC1,STE5,TPS3,MET22,CIN5,YKU80,CYR1,PFY1,YRM1,GPX1,IQG1,GRE2,DPL1,GCY1,BMH1,MUS81,PRE1,GAD1,RGT2,MPT5,YKU70,AZF1,FAR11,HSM3,CCP1,RFA1,GLO2,UGA2,TDP1,XRS2 GO:0009056 4 catabolism 369 0,0572 102 0,1278 1,72E-13 E SCL1,PFK26,AMA1,SDH2,TDH3,PRE7,RPN11,REC114,RPN7,ZWF1,ALD3,RPT1,LSC1,CNE1,YPR1,SHP1,PUT1,PUP2,PRE10,HMX1,RPT2,RPN5,NTH2,RPT3,ASI2,PAP2,PAI3,UBC4,TDH2,TKL2,DDI1,PFK27,UBX7,SPO11,MDH1,KGD1,SKP1,NTA1,MAL12,PCL6,NPL4,UFD1,GRR1,PRB1,SOL4,VID30,RPN9,BRO1,JSN1,UFD2,FMS1,SDH1,RAD50,CIT3,GPH1,ASP3-3,SGA1,DHH1,XKS1,ENO1,SRY1,DOA1,GPM1,APC9,CHA1,MRK1,RAD6,RPN3,GRE3,ARO80,DCS1,CAR2,PUP1,PCL7,ALD2,ENO2,GLO4,DAK2,RPN6,SEC12,ASP3-4,CIT1,NTH1,UBX6,GCY1,KGD2,SDH3,PRE1,GAD1,MPT5,YTA7,ARO10,PUT3,UBX5,LAP4,GLO2,TDH1,UGA2,QRI8,GDB1,SDH4,XRS2 GO:0006950 4 response to stress 395 0,0612 105 0,1316 1,11E-12 E BDF1,SAC6,SIP2,SIP18,FRT2,GLR1,RPD3,ZWF1,ALD3,HOR7,FYV6,DOG2,HSP82,PUP2,LSP1,PHO2,YIM1,STF2,NTH2,RAD59,DDR48,UBC4,MCR1,AIP1,LAS17,SOD1,RAD2,HYS2,ASK10,RPH1,PRB1,SIP5,AHA1,RAD18,LRE1,CTT1,YBP1,NCE103,MMS4,UFD2,MAG1,RAD50,MEC1,KAR2,ASP3-3,PAN3,XBP1,IMP2prime,RIM11,SLG1,HSP104,GRX2,DOA1,SSK2,HSP78,HCH1,PHR1,SSA4,RAD1,SSA3,UBI4,TPS1,MRK1,POS5,RAD6,GRE3,TSL1,EXO1,RAD52,GRX1,RAD26,BCY1,YAP1,DAK2,MYO3,HSC82,BMH2,PIL1,ASP3-4,HSP26,AGP2,NTH1,YDC1,TPS3,MET22,CIN5,YKU80,CYR1,PFY1,GPX1,IQG1,GRE2,DPL1,GCY1,BMH1,MUS81,PRE1,GAD1,YKU70,HSM3,CCP1,RFA1,UGA2,TDP1,XRS2 GO:0044248 5 cellular catabolism 347 0,0538 95 0,119 4,02E-12 E SCL1,PFK26,SDH2,TDH3,PRE7,RPN11,REC114,RPN7,ZWF1,ALD3,RPT1,LSC1,CNE1,YPR1,SHP1,PUT1,PUP2,PRE10,HMX1,RPT2,RPN5,NTH2,RPT3,ASI2,PAP2,UBC4,TDH2,TKL2,DDI1,PFK27,UBX7,SPO11,MDH1,KGD1,SKP1,MAL12,PCL6,NPL4,UFD1,GRR1,SOL4,VID30,RPN9,BRO1,JSN1,UFD2,FMS1,SDH1,RAD50,CIT3,GPH1,ASP3-3,SGA1,DHH1,XKS1,ENO1,SRY1,DOA1,GPM1,APC9,CHA1,RAD6,RPN3,GRE3,ARO80,DCS1,CAR2,PUP1,PCL7,ALD2,ENO2,GLO4,DAK2,RPN6,SEC12,ASP3-4,CIT1,NTH1,UBX6,GCY1,KGD2,SDH3,PRE1,GAD1,MPT5,ARO10,PUT3,UBX5,GLO2,TDH1,UGA2,QRI8,GDB1,SDH4,XRS2 GO:0051179 3 localization 991 0,1535 199 0,2494 1,48E-11 E PEX8,VPS29,MLC1,SAC6,GYP7,ISA2,ARC40,ATG4,SDH2,YMR1,NPL3,APS1,SHR5,TAZ1,MTM1,KIN1,SMY1,ADY2,SHE2,ARC35,YRR1,MDM31,SNX41,ARC15,YPT1,FIT2,QCR8,SFT2,SNC1,ATP2,COX6,STF2,PMP3,ATP5,SSQ1,BET3,MCR1,DDI1,SMF3,SKP1,LAS17,KIN2,VPS60,ERV14,QCR10,KRE11,PTK2,FAA1,UFD1,ARP3,SEC17,NDI1,JEN1,PEX3,COT1,YIP4,GSF2,ADP1,VPS73,SYN8,VPS5,APL1,ENA2,BRO1,HXT6,HXT16,GTS1,AQY1,PEX22,PEX25,ATG9,PEP12,APM2,COX8,SDH1,CYB2,SCD5,RIP1,QCR6,SDS22,CSE1,BET5,SEC6,KAR2,HXT5,SAM50,TOM6,MEX67,ECM10,NCE102,YIP5,FIT3,MYO4,GGA1,SLG1,AVT3,RAV2,VPS17,SEC9,VAC8,IMP1,SEC10,GOS1,MCH1,HXT7,VTI1,GEM1,PXA2,ERD2,HSP78,SCO2,PEX5,PXA1,RHO3,SSA4,ENT5,SSA3,OCT1,MSB3,THP1,TIM21,SNX4,ARP2,SSC1,MUP3,TPM2,VPS38,YPT52,EXO70,YAP1801,VPS30,INH1,ATG7,VPS52,ATP15,PEX19,PAP1,ATG12,ENT1,MRL1,ATG19,VMR1,MYO3,PIC2,PEP8,RTG1,QCR9,VPS15,TPM1,SEC12,YOR1,SEC15,COX4,YPT7,ENT3,AGP2,MDM10,ATP16,RCY1,PEX12,MTR10,PFY1,YRM1,BUL1,MAD1,SSP120,ASM4,DIP5,RPB4,YPK1,SDH3,SSA1,MPT5,PEP1,SDS24,QCR2,CYC7,ARC19,VPS70,EMP46,VPS21,BOR1,BSD2,VPS45,NYV1,HXT13,SSO1,ATP3,SEC28,CRM1,VPS8,ATP17,PEP7,SPO14,EDE1,LSB5,QCR7,SDH4,CLC1 GO:0006810 4,5 transport 924 0,1432 181 0,2268 3,45E-09 E PEX8,VPS29,MLC1,SAC6,GYP7,ISA2,ATG4,SDH2,YMR1,NPL3,APS1,TAZ1,MTM1,KIN1,SMY1,ADY2,YRR1,SNX41,YPT1,FIT2,QCR8,SFT2,SNC1,ATP2,COX6,STF2,PMP3,ATP5,BET3,MCR1,DDI1,SKP1,LAS17,KIN2,VPS60,ERV14,QCR10,KRE11,PTK2,FAA1,UFD1,SEC17,NDI1,JEN1,PEX3,COT1,YIP4,GSF2,ADP1,VPS73,SYN8,VPS5,APL1,ENA2,BRO1,HXT6,HXT16,GTS1,AQY1,PEX22,PEX25,ATG9,PEP12,APM2,COX8,SDH1,CYB2,SCD5,RIP1,QCR6,SDS22,CSE1,BET5,SEC6,KAR2,HXT5,SAM50,TOM6,MEX67,ECM10,YIP5,FIT3,GGA1,SLG1,AVT3,RAV2,VPS17,SEC9,VAC8,IMP1,SEC10,GOS1,MCH1,HXT7,VTI1,GEM1,PXA2,HSP78,SCO2,PEX5,PXA1,RHO3,SSA4,ENT5,SSA3,OCT1,MSB3,THP1,TIM21,SNX4,SSC1,MUP3,TPM2,VPS38,YPT52,EXO70,YAP1801,VPS30,INH1,ATG7,VPS52,ATP15,PEX19,PAP1,ATG12,ENT1,MRL1,ATG19,VMR1,MYO3,PIC2,PEP8,QCR9,VPS15,TPM1,SEC12,YOR1,SEC15,COX4,YPT7,ENT3,AGP2,ATP16,RCY1,PEX12,MTR10,PFY1,YRM1,MAD1,ASM4,DIP5,RPB4,YPK1,SDH3,SSA1,MPT5,PEP1,SDS24,QCR2,CYC7,VPS70,EMP46,VPS21,BOR1,BSD2,VPS45,NYV1,HXT13,SSO1,ATP3,SEC28,CRM1,VPS8,ATP17,PEP7,SPO14,EDE1,LSB5,QCR7,SDH4,CLC1 GO:0051234 4 establishment of localization 942 0,146 183 0,2293 5,45E-09 E PEX8,VPS29,MLC1,SAC6,GYP7,ISA2,ATG4,SDH2,YMR1,NPL3,APS1,TAZ1,MTM1,KIN1,SMY1,ADY2,YRR1,SNX41,YPT1,FIT2,QCR8,SFT2,SNC1,ATP2,COX6,STF2,PMP3,ATP5,BET3,MCR1,DDI1,SKP1,LAS17,KIN2,VPS60,ERV14,QCR10,KRE11,PTK2,FAA1,UFD1,SEC17,NDI1,JEN1,PEX3,COT1,YIP4,GSF2,ADP1,VPS73,SYN8,VPS5,APL1,ENA2,BRO1,HXT6,HXT16,GTS1,AQY1,PEX22,PEX25,ATG9,PEP12,APM2,COX8,SDH1,CYB2,SCD5,RIP1,QCR6,SDS22,CSE1,BET5,SEC6,KAR2,HXT5,SAM50,TOM6,MEX67,ECM10,NCE102,YIP5,FIT3,GGA1,SLG1,AVT3,RAV2,VPS17,SEC9,VAC8,IMP1,SEC10,GOS1,MCH1,HXT7,VTI1,GEM1,PXA2,HSP78,SCO2,PEX5,PXA1,RHO3,SSA4,ENT5,SSA3,OCT1,MSB3,THP1,TIM21,SNX4,SSC1,MUP3,TPM2,VPS38,YPT52,EXO70,YAP1801,VPS30,INH1,ATG7,VPS52,ATP15,PEX19,PAP1,ATG12,ENT1,MRL1,ATG19,VMR1,MYO3,PIC2,PEP8,QCR9,VPS15,TPM1,SEC12,YOR1,SEC15,COX4,YPT7,ENT3,AGP2,ATP16,RCY1,PEX12,MTR10,PFY1,YRM1,MAD1,SSP120,ASM4,DIP5,RPB4,YPK1,SDH3,SSA1,MPT5,PEP1,SDS24,QCR2,CYC7,VPS70,EMP46,VPS21,BOR1,BSD2,VPS45,NYV1,HXT13,SSO1,ATP3,SEC28,CRM1,VPS8,ATP17,PEP7,SPO14,EDE1,LSB5,QCR7,SDH4,CLC1 GO:0006412 7,6 protein biosynthesis 783 0,1213 43 0,0539 5,45E-09 D CBS2,MEF2,SHR5,COX14,MRPL1,PPH22,PTH1,MSY1,RSM23,PBN1,MRPS18,RPL5,ALG2,FAA1,BET4,MRPL28,PMT2,SWS2,MRP20,MSF1,IST1,FMT1,NAM2,SLF1,ILS1,ALG13,ECM32,MSK1,PET123,EAP1,MRP8,MRPL16,MSR1,RSM18,YMR31,MRP51,KTR4,MST1,UGP1,MRPL31,HYP2,RSM28,GPI19 GO:0016072 7 rRNA metabolism 254 0,0394 3 0,0038 1,26E-08 D PAP2,PRP12,POP5 GO:0043037 8,7 translation 415 0,0643 14 0,0175 3,22E-08 D MEF2,COX14,MSY1,FMT1,NAM2,SLF1,ECM32,MSK1,EAP1,MSR1,MRP51,MST1,HYP2,RSM28 GO:0006119 6,8 oxidative phosphorylation 46 0,0071 24 0,0301 6,10E-08 E SDH2,TAZ1,QCR8,ATP2,COX6,STF2,ATP5,QCR10,NDI1,COX8,SDH1,RIP1,QCR6,INH1,ATP15,QCR9,COX4,ATP16,SDH3,QCR2,ATP3,ATP17,QCR7,SDH4 GO:0006112 7 energy reserve metabolism 34 0,0053 20 0,0251 1,41E-07 E SHP1,GLC3,NTH2,PCL6,GLC8,GLG2,PPG1,GLG1,GPH1,SGA1,TPS1,TSL1,PCL7,BMH2,NTH1,YPI1,TPS3,GSY2,BMH1,GDB1 GO:0006118 6,5 electron transport 31 0,0048 19 0,0238 1,52E-07 E SDH2,TAZ1,QCR8,COX6,MCR1,QCR10,NDI1,COX8,SDH1,CYB2,RIP1,QCR6,QCR9,COX4,SDH3,QCR2,CYC7,QCR7,SDH4 GO:0006092 7 main pathways of carbohydrate metabolism 70 0,0108 29 0,0363 6,97E-07 E PFK26,SDH2,TDH3,ZWF1,LSC1,FYV10,RMD5,TDH2,TKL2,PFK27,MDH1,KGD1,SOL4,VID30,CIT2,SDH1,CIT3,UBC8,ENO1,IDP3,GPM1,ENO2,CIT1,GID8,KGD2,SDH3,MDH3,TDH1,SDH4 GO:0007028 5 cytoplasm organization and biogenesis 253 0,0392 5 0,0063 9,61E-07 D RPL5,TOR1,PRP12,POP5,CRM1 GO:0042254 6 ribosome biogenesis and assembly 253 0,0392 5 0,0063 9,61E-07 D RPL5,TOR1,PRP12,POP5,CRM1 GO:0009057 5 macromolecule catabolism 280 0,0434 70 0,0877 1,51E-06 E SCL1,PFK26,AMA1,TDH3,PRE7,RPN11,RPN7,ZWF1,RPT1,CNE1,YPR1,SHP1,PUP2,PRE10,RPT2,RPN5,NTH2,RPT3,ASI2,PAP2,PAI3,UBC4,TDH2,TKL2,DDI1,PFK27,UBX7,SKP1,NTA1,MAL12,PCL6,NPL4,UFD1,GRR1,PRB1,SOL4,VID30,RPN9,BRO1,JSN1,UFD2,GPH1,SGA1,DHH1,XKS1,ENO1,DOA1,GPM1,APC9,MRK1,RAD6,RPN3,GRE3,DCS1,PUP1,PCL7,ENO2,RPN6,SEC12,NTH1,UBX6,GCY1,PRE1,MPT5,YTA7,UBX5,LAP4,TDH1,QRI8,GDB1 GO:0042773 7,9,6 ATP synthesis coupled electron transport 25 0,0039 16 0,0201 1,81E-06 E SDH2,TAZ1,QCR8,COX6,QCR10,NDI1,COX8,SDH1,RIP1,QCR6,QCR9,COX4,SDH3,QCR2,QCR7,SDH4 GO:0042775 8,10,7 ATP synthesis coupled electron transport (sensu Eukaryota) 25 0,0039 16 0,0201 1,81E-06 E SDH2,TAZ1,QCR8,COX6,QCR10,NDI1,COX8,SDH1,RIP1,QCR6,QCR9,COX4,SDH3,QCR2,QCR7,SDH4 GO:0043285 5,6 biopolymer catabolism 157 0,0243 47 0,0589 1,94E-06 E SCL1,AMA1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,PAI3,UBC4,DDI1,UBX7,SKP1,NTA1,PCL6,NPL4,UFD1,GRR1,PRB1,VID30,RPN9,BRO1,UFD2,GPH1,SGA1,DOA1,APC9,MRK1,RAD6,RPN3,PUP1,PCL7,RPN6,SEC12,UBX6,PRE1,YTA7,UBX5,LAP4,QRI8,GDB1 GO:0051186 5 cofactor metabolism 148 0,0229 45 0,0564 2,50E-06 E SDH2,ZWF1,LSC1,COQ6,COX15,ACS1,HMX1,ATP2,STF2,ATP5,TKL2,QNS1,MDH1,KGD1,ISU1,PDX1,COQ9,SOL4,FMS1,SDH1,CIT3,PNC1,FAD1,BNA1,IDP3,ACH1,BIO3,POS5,INH1,ATP15,QCR9,COQ4,CIT1,COQ3,GUT2,ATP16,KGD2,SDH3,HEM15,ATP3,ATP17,VHS3,MDH3,SDH4,NDE1 GO:0006732 6 coenzyme metabolism 119 0,0184 39 0,0489 2,81E-06 E SDH2,ZWF1,LSC1,COQ6,ACS1,ATP2,STF2,ATP5,TKL2,QNS1,MDH1,KGD1,PDX1,COQ9,SOL4,FMS1,SDH1,CIT3,PNC1,FAD1,BNA1,IDP3,ACH1,POS5,INH1,ATP15,COQ4,CIT1,COQ3,GUT2,ATP16,KGD2,SDH3,ATP3,ATP17,VHS3,MDH3,SDH4,NDE1 GO:0005996 6,7 monosaccharide metabolism 92 0,0143 33 0,0414 3,72E-06 E PGM2,PFK26,TDH3,ZWF1,YPR1,DOG2,FYV10,RMD5,TDH2,TKL2,PFK27,GND2,XYL2,SOL4,VID30,FBP26,HXK1,UBC8,XKS1,ENO1,PSK2,GPM1,GAL7,GRE3,GAL10,IPK1,ENO2,GID8,GLK1,GCY1,UGP1,INO1,TDH1 GO:0009060 8 aerobic respiration 84 0,013 31 0,0388 5,05E-06 E SDH2,LSC1,COX14,MRPL1,QCR8,COX6,MDH1,KGD1,QCR10,COQ9,MCT1,DLD1,ADE16,COX8,SDH1,RIP1,QCR6,CIT3,ETR1,MBR1,COR1,COX20,QCR9,CIT1,COX4,RSF1,KGD2,SDH3,QCR2,QCR7,SDH4 GO:0016310 7 phosphorylation 143 0,0222 43 0,0539 8,10E-06 E SIP2,SDH2,TAZ1,QCR8,ATP2,COX6,STF2,ATP5,SLT2,PKH2,KNS1,QCR10,NDI1,STE11,TPK1,COX8,SDH1,RIP1,QCR6,RIM11,PBS2,PSK2,TPK2,SSK2,LSB6,MRK1,CMK1,RCK2,INH1,KIN82,ATP15,QCR9,VPS15,COX4,ATP16,YPK1,SDH3,YPK2,QCR2,ATP3,ATP17,QCR7,SDH4 GO:0016192 5,6 vesicle-mediated transport 282 0,0437 68 0,0852 1,23E-05 E VPS29,MLC1,SAC6,GYP7,YMR1,APS1,KIN1,SMY1,YPT1,SFT2,SNC1,BET3,DDI1,LAS17,KIN2,VPS60,ERV14,KRE11,SEC17,YIP4,VPS5,APL1,PEP12,APM2,SCD5,BET5,SEC6,YIP5,GGA1,SLG1,VPS17,SEC9,SEC10,GOS1,VTI1,GEM1,RHO3,ENT5,MSB3,TPM2,VPS38,YPT52,EXO70,YAP1801,VPS52,ENT1,MYO3,PEP8,TPM1,SEC12,SEC15,YPT7,ENT3,RCY1,YPK1,SDS24,EMP46,VPS21,VPS45,NYV1,SSO1,SEC28,VPS8,PEP7,SPO14,EDE1,LSB5,CLC1 GO:0007046 7 ribosome biogenesis 214 0,0332 4 0,005 1,38E-05 D TOR1,PRP12,POP5,CRM1 GO:0006364 8 rRNA processing 176 0,0273 2 0,0025 2,05E-05 D PRP12,POP5 GO:0016070 6 RNA metabolism 539 0,0835 30 0,0376 2,26E-05 D USA1,PRP5,ECM2,TAD3,MSY1,LUC7,PAP2,CET1,UFD1,SNU71,JSN1,MSL5,PAN3,FMT1,NAM2,DHH1,CUS2,SWD2,MSK1,DCS1,PRP4,RSE1,PRP12,PAP1,POP5,MSR1,TRM12,MST1,PRP22,MPT5 GO:0045333 7 cellular respiration 89 0,0138 31 0,0388 2,41E-05 E SDH2,LSC1,COX14,MRPL1,QCR8,COX6,MDH1,KGD1,QCR10,COQ9,MCT1,DLD1,ADE16,COX8,SDH1,RIP1,QCR6,CIT3,ETR1,MBR1,COR1,COX20,QCR9,CIT1,COX4,RSF1,KGD2,SDH3,QCR2,QCR7,SDH4 GO:0044265 6 cellular macromolecule catabolism 258 0,04 63 0,0789 2,57E-05 E SCL1,PFK26,TDH3,PRE7,RPN11,RPN7,ZWF1,RPT1,CNE1,YPR1,SHP1,PUP2,PRE10,RPT2,RPN5,NTH2,RPT3,ASI2,PAP2,UBC4,TDH2,TKL2,DDI1,PFK27,UBX7,SKP1,MAL12,PCL6,NPL4,UFD1,GRR1,SOL4,VID30,RPN9,BRO1,JSN1,UFD2,GPH1,SGA1,DHH1,XKS1,ENO1,DOA1,GPM1,APC9,RAD6,RPN3,GRE3,DCS1,PUP1,PCL7,ENO2,RPN6,SEC12,NTH1,UBX6,GCY1,PRE1,MPT5,UBX5,TDH1,QRI8,GDB1 GO:0030163 6,7 protein catabolism 145 0,0225 42 0,0526 3,90E-05 E SCL1,AMA1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,PAI3,UBC4,DDI1,UBX7,SKP1,NTA1,NPL4,UFD1,GRR1,PRB1,VID30,RPN9,BRO1,UFD2,DOA1,APC9,MRK1,RAD6,RPN3,PUP1,RPN6,SEC12,UBX6,PRE1,YTA7,UBX5,LAP4,QRI8 GO:0006793 5 phosphorus metabolism 188 0,0291 50 0,0627 4,21E-05 E GIP2,SIP2,SDH2,YMR1,TAZ1,PPH22,QCR8,ATP2,COX6,STF2,ATP5,SLT2,PKH2,KNS1,QCR10,NDI1,STE11,TPK1,PPG1,COX8,SDH1,RIP1,QCR6,RIM11,PBS2,PSK2,TPK2,SSK2,LSB6,PTP2,MRK1,CMK1,RCK2,INH1,KIN82,ATP15,QCR9,VPS15,COX4,YPI1,ATP16,YPK1,SDH3,YPK2,QCR2,LTP1,ATP3,ATP17,QCR7,SDH4 GO:0006796 6 phosphate metabolism 188 0,0291 50 0,0627 4,21E-05 E GIP2,SIP2,SDH2,YMR1,TAZ1,PPH22,QCR8,ATP2,COX6,STF2,ATP5,SLT2,PKH2,KNS1,QCR10,NDI1,STE11,TPK1,PPG1,COX8,SDH1,RIP1,QCR6,RIM11,PBS2,PSK2,TPK2,SSK2,LSB6,PTP2,MRK1,CMK1,RCK2,INH1,KIN82,ATP15,QCR9,VPS15,COX4,YPI1,ATP16,YPK1,SDH3,YPK2,QCR2,LTP1,ATP3,ATP17,QCR7,SDH4 GO:0006084 7 acetyl-CoA metabolism 20 0,0031 13 0,0163 4,92E-05 E SDH2,LSC1,ACS1,MDH1,KGD1,PDX1,SDH1,CIT3,ACH1,CIT1,KGD2,SDH3,SDH4 GO:0006066 5 alcohol metabolism 157 0,0243 44 0,0551 5,35E-05 E PGM2,PFK26,TDH3,SYM1,ZWF1,ADH2,YPR1,DOG2,FYV10,RMD5,MCR1,TDH2,TKL2,PFK27,ERG9,GUT1,GND2,ALD4,XYL2,SOL4,VID30,TCO89,FBP26,HXK1,UBC8,XKS1,DAP1,ENO1,PSK2,GPM1,TGL1,GAL7,GRE3,GAL10,IPK1,ENO2,DAK2,GID8,GLK1,GCY1,UGP1,INO1,TDH1,NDE1 GO:0005977 8,9 glycogen metabolism 27 0,0042 15 0,0188 8,56E-05 E SHP1,GLC3,PCL6,GLC8,GLG2,PPG1,GLG1,GPH1,SGA1,PCL7,BMH2,YPI1,GSY2,BMH1,GDB1 GO:0006508 7 proteolysis 157 0,0243 43 0,0539 0,0001516 E SCL1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,MDJ1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,UBC4,DDI1,UBX7,SKP1,NPL4,UFD1,GRR1,VID30,RPN9,BRO1,UFD2,RIM11,DOA1,APC9,RAD6,RPN3,PUP1,RIM20,RPN6,SEC12,TFS1,ECM14,UBX6,PBI2,PRE1,UBX5,QRI8,PHB1,RPN14 GO:0019318 7,8 hexose metabolism 85 0,0132 28 0,0351 0,0004153 E PGM2,PFK26,TDH3,ZWF1,DOG2,FYV10,RMD5,TDH2,TKL2,PFK27,GND2,SOL4,VID30,FBP26,HXK1,UBC8,ENO1,PSK2,GPM1,GAL7,GAL10,IPK1,ENO2,GID8,GLK1,UGP1,INO1,TDH1 GO:0006511 10,11 ubiquitin-dependent protein catabolism 121 0,0187 35 0,0439 0,0005294 E SCL1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,UBC4,DDI1,UBX7,SKP1,NPL4,UFD1,GRR1,VID30,RPN9,BRO1,UFD2,DOA1,APC9,RAD6,RPN3,PUP1,RPN6,SEC12,UBX6,PRE1,UBX5,QRI8 GO:0019941 9,1 modification-dependent protein catabolism 121 0,0187 35 0,0439 0,0005294 E SCL1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,UBC4,DDI1,UBX7,SKP1,NPL4,UFD1,GRR1,VID30,RPN9,BRO1,UFD2,DOA1,APC9,RAD6,RPN3,PUP1,RPN6,SEC12,UBX6,PRE1,UBX5,QRI8 GO:0044257 7,8 cellular protein catabolism 123 0,0191 35 0,0439 0,0008027 E SCL1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,UBC4,DDI1,UBX7,SKP1,NPL4,UFD1,GRR1,VID30,RPN9,BRO1,UFD2,DOA1,APC9,RAD6,RPN3,PUP1,RPN6,SEC12,UBX6,PRE1,UBX5,QRI8 GO:0051603 8,9 proteolysis during cellular protein catabolism 123 0,0191 35 0,0439 0,0008027 E SCL1,PRE7,RPN11,RPN7,RPT1,CNE1,SHP1,PUP2,PRE10,RPT2,RPN5,RPT3,ASI2,UBC4,DDI1,UBX7,SKP1,NPL4,UFD1,GRR1,VID30,RPN9,BRO1,UFD2,DOA1,APC9,RAD6,RPN3,PUP1,RPN6,SEC12,UBX6,PRE1,UBX5,QRI8 GO:0007165 4 signal transduction 167 0,0259 43 0,0539 0,0009145 E SIP2,SNF3,YMR1,SHR5,STE18,SLT2,PKH2,STE11,MDG1,TPK1,BRO1,RTG2,TUS1,GPB2,TAX4,CDC37,SLG1,PBS2,RGA2,TPK2,SSK2,PDE1,RHO3,COS111,LSB6,PTP2,CMK1,TOR1,RCK2,LEM3,BCY1,AFR1,BMH2,IRA2,DPP1,STE5,RSF1,CYR1,DPL1,BMH1,RAS2,BAG7,RGT2 GO:0006073 7,8 glucan metabolism 39 0,006 17 0,0213 0,0010185 E SHP1,GLC3,PCL6,GLC8,GLG2,PPG1,KRE9,GLG1,GPH1,SGA1,PCL7,BMH2,YPI1,GSY2,BMH1,SKN1,GDB1 GO:0006006 8,9 glucose metabolism 65 0,0101 23 0,0288 0,0010978 E PGM2,PFK26,TDH3,ZWF1,DOG2,FYV10,RMD5,TDH2,TKL2,PFK27,GND2,SOL4,VID30,FBP26,HXK1,UBC8,ENO1,GPM1,ENO2,GID8,GLK1,UGP1,TDH1 GO:0009059 6,5 macromolecule biosynthesis 844 0,1308 65 0,0815 0,0011192 D CBS2,MEF2,TDH3,SHR5,FYV10,GLC3,COX14,MRPL1,PPH22,PTH1,RMD5,MSY1,RSM23,TDH2,PBN1,MRPS18,RPL5,PCL6,ALG2,GLC8,FAA1,BET4,VID30,GLG2,MRPL28,PMT2,SWS2,GLG1,MRP20,MSF1,IST1,FMT1,UBC8,NAM2,ENO1,SLF1,ILS1,GPM1,ALG13,TPS1,ECM32,TSL1,MSK1,PCL7,PET123,EAP1,ENO2,MRP8,MRPL16,MSR1,RSM18,YMR31,TPS3,GSY2,GID8,MRP51,KTR4,MST1,UGP1,MRPL31,HYP2,RSM28,TDH1,GPI19,SKN1 GO:0030029 7 actin filament-based process 104 0,0161 31 0,0388 0,0011494 E SAC6,ARC40,ARC35,PPH22,ARC15,HUA1,AIP1,LAS17,ARP3,BBC1,SCD5,SLG1,PBS2,RGA2,SSK2,CAP2,RHO3,LSB6,MSB3,ARP2,TPM2,VPS52,SCP1,CAP1,ENT1,TPM1,ENT3,PFY1,IQG1,ARC19,LSB5 GO:0051187 6 cofactor catabolism 18 0,0028 11 0,0138 0,0013511 E SDH2,LSC1,HMX1,MDH1,KGD1,SDH1,CIT3,CIT1,KGD2,SDH3,SDH4 GO:0046356 8 acetyl-CoA catabolism 15 0,0023 10 0,0125 0,0013522 E SDH2,LSC1,MDH1,KGD1,SDH1,CIT3,CIT1,KGD2,SDH3,SDH4 GO:0006099 9,8 tricarboxylic acid cycle 15 0,0023 10 0,0125 0,0013522 E SDH2,LSC1,MDH1,KGD1,SDH1,CIT3,CIT1,KGD2,SDH3,SDH4 GO:0030036 8 actin cytoskeleton organization and biogenesis 100 0,0155 30 0,0376 0,0014666 E SAC6,ARC40,ARC35,PPH22,ARC15,HUA1,AIP1,LAS17,ARP3,BBC1,SCD5,SLG1,PBS2,RGA2,SSK2,CAP2,RHO3,LSB6,MSB3,ARP2,TPM2,SCP1,CAP1,ENT1,TPM1,ENT3,PFY1,IQG1,ARC19,LSB5 GO:0007154 3 cell communication 199 0,0308 48 0,0602 0,0016123 E SIP2,SNF3,YMR1,SHR5,PHO2,STE18,SLT2,PKH2,STE11,MDG1,PRB1,SIP5,TPK1,BRO1,RTG2,TUS1,GPB2,ASP3-3,TAX4,CDC37,SLG1,PBS2,RGA2,TPK2,SSK2,PDE1,RHO3,COS111,LSB6,PTP2,CMK1,TOR1,RCK2,LEM3,BCY1,AFR1,BMH2,IRA2,DPP1,ASP3-4,STE5,RSF1,CYR1,DPL1,BMH1,RAS2,BAG7,RGT2 GO:0009628 4 response to abiotic stimulus 301 0,0466 65 0,0815 0,0016307 E ASR1,SAC6,SIP18,SNF3,POG1,GLR1,ZWF1,LSP1,YRR1,CMP2,MLF3,STE18,STF2,OPY2,MCR1,AIP1,LAS17,SOD1,ASK10,GRR1,STE11,MDG1,GTS1,LRE1,YBP1,NCE103,KAR2,AHP1,SLG1,GRX2,RGA2,SSK2,FAR10,PTP2,POS5,SNG1,GRX1,KIN82,CNB1,BCY1,AFR1,YAP1,GLO4,MYO3,PIL1,YOR1,AGP2,YDC1,STE5,MET22,CIN5,CYR1,PFY1,YRM1,GPX1,IQG1,GCY1,GAD1,RGT2,MPT5,AZF1,FAR11,CCP1,GLO2,UGA2 GO:0006457 7 protein folding 67 0,0104 23 0,0288 0,001981 E SSA2,CNE1,MDJ1,HSP82,SSE1,GSF2,AHA1,STI1,SSE2,MPD1,ECM10,HSP104,CPR6,HSP78,HCH1,SSA4,SSA3,SSC1,PEX19,HSC82,HSP26,SSA1,PHB1 GO:0016051 7,6 carbohydrate biosynthesis 63 0,0098 22 0,0276 0,0023893 E TDH3,FYV10,GLC3,RMD5,TDH2,PCL6,GLC8,VID30,GLG2,GLG1,UBC8,ENO1,GPM1,TPS1,TSL1,PCL7,ENO2,TPS3,GSY2,GID8,TDH1,SKN1 GO:0046164 6 alcohol catabolism 37 0,0057 16 0,0201 0,0024016 E PFK26,TDH3,ZWF1,YPR1,TDH2,TKL2,PFK27,SOL4,XKS1,ENO1,GPM1,GRE3,ENO2,DAK2,GCY1,TDH1 GO:0006396 7 RNA processing 346 0,0536 18 0,0226 0,002529 D USA1,PRP5,ECM2,LUC7,CET1,UFD1,SNU71,MSL5,PAN3,NAM2,CUS2,SWD2,PRP4,RSE1,PRP12,PAP1,POP5,PRP22 GO:0006082 5 organic acid metabolism 300 0,0465 64 0,0802 0,0029524 E TDH3,ARO9,ALD3,FYV10,ALD6,PUT1,AYR1,ACS1,PHO2,RMD5,MSY1,FOX2,CAT2,TDH2,MDH1,KGD1,PDX1,MCT1,VID30,CIT2,CIT3,GDH3,ASP3-3,FMT1,ETR1,UBC8,NAM2,ENO1,IDP3,OAF1,GPM1,PDH1,ACH1,CHA1,HST3,BIO3,MSK1,ARO80,CAR2,ALD2,DLD3,ENO2,GLO4,AGX1,TSC13,TRP4,ASP3-4,MSR1,CIT1,AGP2,MET22,PYK2,GID8,KGD2,MST1,GAD1,ARO10,PUT3,GLO2,MDH3,TDH1,UGA2,PDX3,ARG4 GO:0019752 6 carboxylic acid metabolism 300 0,0465 64 0,0802 0,0029524 E TDH3,ARO9,ALD3,FYV10,ALD6,PUT1,AYR1,ACS1,PHO2,RMD5,MSY1,FOX2,CAT2,TDH2,MDH1,KGD1,PDX1,MCT1,VID30,CIT2,CIT3,GDH3,ASP3-3,FMT1,ETR1,UBC8,NAM2,ENO1,IDP3,OAF1,GPM1,PDH1,ACH1,CHA1,HST3,BIO3,MSK1,ARO80,CAR2,ALD2,DLD3,ENO2,GLO4,AGX1,TSC13,TRP4,ASP3-4,MSR1,CIT1,AGP2,MET22,PYK2,GID8,KGD2,MST1,GAD1,ARO10,PUT3,GLO2,MDH3,TDH1,UGA2,PDX3,ARG4 GO:0046365 7,8 monosaccharide catabolism 34 0,0053 15 0,0188 0,0036806 E PFK26,TDH3,ZWF1,YPR1,TDH2,TKL2,PFK27,SOL4,XKS1,ENO1,GPM1,GRE3,ENO2,GCY1,TDH1 GO:0016052 6 carbohydrate catabolism 71 0,011 23 0,0288 0,0058955 E PFK26,TDH3,ZWF1,YPR1,NTH2,TDH2,TKL2,PFK27,MAL12,PCL6,SOL4,GPH1,SGA1,XKS1,ENO1,GPM1,GRE3,PCL7,ENO2,NTH1,GCY1,TDH1,GDB1 GO:0044275 7 cellular carbohydrate catabolism 71 0,011 23 0,0288 0,0058955 E PFK26,TDH3,ZWF1,YPR1,NTH2,TDH2,TKL2,PFK27,MAL12,PCL6,SOL4,GPH1,SGA1,XKS1,ENO1,GPM1,GRE3,PCL7,ENO2,NTH1,GCY1,TDH1,GDB1 GO:0009109 7 coenzyme catabolism 17 0,0026 10 0,0125 0,0067447 E SDH2,LSC1,MDH1,KGD1,SDH1,CIT3,CIT1,KGD2,SDH3,SDH4 GO:0009451 7 RNA modification 126 0,0195 2 0,0025 0,0089654 D TAD3,TRM12 GO:0051641 5,4 cellular localization 521 0,0807 96 0,1203 0,0093889 E PEX8,VPS29,MLC1,ARC40,ATG4,NPL3,ARC35,MDM31,ARC15,YPT1,SFT2,SNC1,BET3,SKP1,VPS60,ERV14,KRE11,ARP3,SEC17,PEX3,VPS73,VPS5,BRO1,PEX22,PEX25,ATG9,PEP12,SDS22,CSE1,BET5,SEC6,KAR2,SAM50,TOM6,MEX67,ECM10,GGA1,RAV2,VPS17,SEC9,VAC8,IMP1,SEC10,GOS1,VTI1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,THP1,TIM21,ARP2,SSC1,TPM2,VPS38,YPT52,EXO70,VPS30,ATG7,VPS52,PEX19,PAP1,ATG12,MRL1,ATG19,PEP8,VPS15,TPM1,SEC12,SEC15,YPT7,ENT3,MDM10,PEX12,MTR10,PFY1,BUL1,MAD1,ASM4,RPB4,SSA1,MPT5,PEP1,ARC19,VPS70,EMP46,VPS21,BSD2,VPS45,SSO1,SEC28,CRM1,VPS8,PEP7 GO:0000001 8,7 mitochondrion inheritance 25 0,0039 12 0,015 0,0123514 E MLC1,ARC40,ARC35,MDM31,ARC15,ARP3,ARP2,TPM2,TPM1,MDM10,BUL1,ARC19 GO:0051646 6,5 mitochondrion localization 25 0,0039 12 0,015 0,0123514 E MLC1,ARC40,ARC35,MDM31,ARC15,ARP3,ARP2,TPM2,TPM1,MDM10,BUL1,ARC19 GO:0048311 7,6 mitochondrion distribution 25 0,0039 12 0,015 0,0123514 E MLC1,ARC40,ARC35,MDM31,ARC15,ARP3,ARP2,TPM2,TPM1,MDM10,BUL1,ARC19 GO:0006122 9,11,8 mitochondrial electron transport, ubiquinol to cytochrome c 9 0,0014 7 0,0088 0,0130136 E QCR8,QCR10,RIP1,QCR6,QCR9,QCR2,QCR7 GO:0008154 9,6 actin polymerization and/or depolymerization 9 0,0014 7 0,0088 0,0130136 E AIP1,LAS17,CAP2,TPM2,CAP1,TPM1,PFY1 GO:0048308 6 organelle inheritance 38 0,0059 15 0,0188 0,0182333 E MLC1,ARC40,ARC35,MDM31,ARC15,ARP3,MYO4,VAC8,ARP2,TPM2,TPM1,YPT7,MDM10,BUL1,ARC19 GO:0044270 6,5 nitrogen compound catabolism 31 0,0048 13 0,0163 0,0312208 E ALD3,PUT1,FMS1,ASP3-3,CHA1,ARO80,CAR2,ALD2,ASP3-4,GAD1,ARO10,PUT3,UGA2 GO:0009310 6,7 amine catabolism 31 0,0048 13 0,0163 0,0312208 E ALD3,PUT1,FMS1,ASP3-3,CHA1,ARO80,CAR2,ALD2,ASP3-4,GAD1,ARO10,PUT3,UGA2 GO:0000003 2 reproduction 255 0,0395 53 0,0664 0,0394378 E BDF1,MLC1,SAC6,AMA1,POG1,SHP1,PUP2,CMP2,PPH22,STE18,OPY2,UBC4,LAS17,ERV14,GRR1,STE11,MDG1,PRM5,GTS1,AQY1,RIM21,ADE16,SEC6,KAR2,SGA1,RIM11,SEC10,RGA2,FAR10,UBI4,PTP2,MUB1,TPM2,EXO70,CNB1,NEM1,EMI2,AFR1,PRM8,DIT1,MYO3,BMH2,TPM1,SEC15,STE5,PFY1,BMH1,RAS2,PRE1,MPT5,FAR11,REH1,SPO14 GO:0008152 3 metabolism 3427 0,531 472 0,5915 0,0397049 E SSA2,BDF1,GIP2,SCL1,CBS2,TFG1,PGM2,MEF2,ADR1,SIP2,MAL13,PFK26,SRL3,AMA1,SDH2,USA1,ULA1,TDH3,PRE7,UBR1,POG1,RPN11,ARO9,GLR1,YMR1,REC114,RPN7,RPD3,SYM1,ZWF1,ALD3,RPT1,FYV6,LSC1,SHR5,ADH2,CNE1,PRP5,TAZ1,YPR1,MED4,DOG2,ECM2,COQ6,COX15,SHP1,MDJ1,HSP82,FYV10,ADY2,ALD6,LEO1,PUT1,GLC3,PUP2,AYR1,COX14,YRR1,MRPL1,RIB4,SIZ1,PPH22,PTH1,ACS1,RPB7,YPT1,PRE10,HMX1,QCR8,PHO2,TAD3,SPT2,RPT2,RMD5,MSY1,ATP2,COX6,FOX2,STF2,SNF4,YAF9,ATP5,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,SSQ1,LAG1,RAD59,SCT1,PAP2,ATP10,PAI3,OSH6,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SET3,UBX7,RIB5,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,LAS17,ERG9,SOD1,RAD2,RUP1,CRD1,NTA1,HYS2,MAL12,CSG2,EHT1,PCL6,ASK10,KNS1,ISU1,NPL4,PDX1,QCR10,GUT1,ALG2,UBP15,GLC8,SSE1,COQ9,FAA1,GND2,CBP4,UFD1,MCT1,GRR1,BET4,NDI1,STE11,ALD4,RPH1,PRB1,GSF2,SNU71,AHA1,XYL2,SOL4,VID30,RPN9,UBP6,ISW1,CST6,NPR1,AOS1,GLG2,MRPL28,UGA3,TPK1,TCO89,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,STI1,DLD1,PRI1,GTS1,CIT2,PPG1,PMT2,SWS2,YBP1,NCE103,HXK1,MMS4,SSE2,UFD2,ADE16,COX8,FMS1,MAG1,SDH1,RAD50,KRE9,CYB2,MEC1,RIP1,QCR6,CIT3,GLG1,MRP20,GDH3,CCL1,GPH1,DAP2,RPO41,MSF1,PNC1,FAD1,ASP3-3,SAM50,MPD1,IST1,INO4,CDC73,ECM10,SGA1,BNA1,MSL5,PAN3,YRF1-2,FMT1,TGL4,ETR1,IMP2prime,RIM11,UBC8,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,TRA1,XKS1,IMP1,DAP1,SET2,ENO1,PSK2,MCM3,SRY1,CPR6,PPM1,CUS2,IDP3,SLF1,GRX2,DOA1,ILS1,OAF1,TPK2,GPM1,SSK2,CAP2,HSP78,EPL1,HCH1,PHR1,PDH1,SSA4,ACH1,TGL1,APC9,CHA1,RAD1,HST3,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,THP1,TPS1,BIO3,PTP2,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,ECM32,GRE3,SIF2,MBR1,TSL1,RCK2,GAL10,RSC9,IPK1,STR2,SSC1,MSK1,PHO23,ARO80,TPM2,DCS1,COR1,PRP4,RSE1,EXO1,THI21,RAD52,INH1,GRX1,CAR2,KIN82,PUP1,COX20,PRP12,RAD26,PCL7,RIM20,ALD2,ATP15,APA1,UBA3,PET123,EAP1,DLD3,ENO2,PEX19,CAP1,YAP1,PAP1,GLO4,AGX1,MRP8,DAK2,THI3,RPN6,RTG1,SWI5,HSC82,QCR9,BMH2,TSC13,POP5,VPS15,TRP4,MRPL16,TPM1,SEC12,DPP1,COQ4,ASP3-4,MSR1,HSP26,HAP2,CIT1,ADE8,AHC1,RSM18,MAL33,PAF1,COX4,TFS1,GPT2,AGP2,MUM2,MDM10,COQ3,NTH1,YMR31,IZH3,YDC1,YPI1,TPS3,GUT2,TRM12,ATP16,MET22,ECM14,CIN5,UBP2,PRP45,RSF1,RIM4,YKU80,CYR1,HAP5,PFY1,YRM1,PYK2,GPX1,BUL1,GSY2,GID8,UBX6,GLK1,MRP51,DPL1,KTR4,GCY1,BMH1,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,CHO1,SSA1,NUT2,PRE1,GAD1,HEM15,MPT5,YKU70,AZF1,MRPL31,YTA7,ARO10,SNF5,PUT3,HYP2,YPK2,ARA1,HSM3,SDS24,YPC1,UBX5,CCP1,QCR2,CKI1,CYC7,LAP4,RFA1,GLO2,LTP1,INO1,VPS45,ATP3,RSM28,ADE2,ATP17,VHS3,MDH3,TDH1,UGA2,CSR2,QRI8,GPI19,PHB1,SKN1,PDX3,GDB1,TDP1,STE24,SPO14,ARG4,RPN14,GAL11,QCR7,APA2,SDH4,NDE1,XRS2 GO:0006887 6,7 exocytosis 36 0,0056 14 0,0175 0,0417156 E KIN1,SMY1,KIN2,SEC6,SEC10,RHO3,MSB3,TPM2,EXO70,MYO3,TPM1,SEC15,PEP7,SPO14 GO:0006733 7 oxidoreduction coenzyme metabolism 45 0,007 16 0,0201 0,0426195 E ZWF1,COQ6,TKL2,QNS1,COQ9,SOL4,PNC1,FAD1,BNA1,IDP3,POS5,COQ4,COQ3,GUT2,MDH3,NDE1 GO:0042221 5 response to chemical stimulus 220 0,0341 47 0,0589 0,0520737 E ASR1,SNF3,POG1,GLR1,ZWF1,YRR1,CMP2,MLF3,STE18,OPY2,MCR1,SOD1,ASK10,GRR1,STE11,MDG1,GTS1,YBP1,NCE103,KAR2,AHP1,GRX2,RGA2,FAR10,PTP2,POS5,SNG1,GRX1,KIN82,CNB1,AFR1,YAP1,GLO4,YOR1,STE5,CIN5,CYR1,YRM1,GPX1,GAD1,RGT2,MPT5,AZF1,FAR11,CCP1,GLO2,UGA2 GO:0006892 9,7,6,8 post-Golgi transport 51 0,0079 17 0,0213 0,0620099 E SFT2,SNC1,PEP12,SEC6,GGA1,SEC9,SEC10,VTI1,ENT5,EXO70,VPS52,SEC15,YPT7,ENT3,VPS45,SSO1,PEP7 GO:0044237 4 cellular metabolism 3376 0,5231 463 0,5802 0,0837603 E SSA2,BDF1,GIP2,SCL1,CBS2,TFG1,PGM2,MEF2,ADR1,SIP2,MAL13,PFK26,SRL3,SDH2,USA1,ULA1,TDH3,PRE7,UBR1,POG1,RPN11,ARO9,GLR1,YMR1,REC114,RPN7,RPD3,SYM1,ZWF1,ALD3,RPT1,FYV6,LSC1,SHR5,ADH2,CNE1,PRP5,TAZ1,YPR1,MED4,DOG2,ECM2,COQ6,COX15,SHP1,MDJ1,HSP82,FYV10,ADY2,ALD6,LEO1,PUT1,GLC3,PUP2,AYR1,COX14,YRR1,MRPL1,RIB4,SIZ1,PPH22,PTH1,ACS1,RPB7,YPT1,PRE10,HMX1,QCR8,PHO2,TAD3,SPT2,RPT2,RMD5,MSY1,ATP2,COX6,FOX2,STF2,SNF4,YAF9,ATP5,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,SSQ1,LAG1,RAD59,SCT1,PAP2,ATP10,OSH6,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SET3,UBX7,RIB5,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,LAS17,ERG9,SOD1,RAD2,RUP1,CRD1,NTA1,HYS2,MAL12,CSG2,PCL6,ASK10,KNS1,ISU1,NPL4,PDX1,QCR10,GUT1,ALG2,UBP15,GLC8,SSE1,COQ9,FAA1,GND2,CBP4,UFD1,MCT1,GRR1,BET4,NDI1,STE11,ALD4,RPH1,GSF2,SNU71,AHA1,XYL2,SOL4,VID30,RPN9,UBP6,ISW1,CST6,AOS1,GLG2,MRPL28,UGA3,TPK1,TCO89,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,STI1,DLD1,PRI1,GTS1,CIT2,PPG1,PMT2,SWS2,YBP1,NCE103,HXK1,MMS4,SSE2,UFD2,ADE16,COX8,FMS1,MAG1,SDH1,RAD50,KRE9,CYB2,MEC1,RIP1,QCR6,CIT3,GLG1,MRP20,GDH3,CCL1,GPH1,DAP2,RPO41,MSF1,PNC1,FAD1,ASP3-3,SAM50,MPD1,IST1,INO4,CDC73,ECM10,SGA1,BNA1,MSL5,PAN3,YRF1-2,FMT1,TGL4,ETR1,IMP2prime,RIM11,UBC8,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,TRA1,XKS1,IMP1,DAP1,SET2,ENO1,PSK2,MCM3,SRY1,CPR6,PPM1,CUS2,IDP3,SLF1,GRX2,DOA1,ILS1,OAF1,TPK2,GPM1,SSK2,CAP2,HSP78,EPL1,HCH1,PHR1,PDH1,SSA4,ACH1,TGL1,APC9,CHA1,RAD1,HST3,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,THP1,TPS1,BIO3,PTP2,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,ECM32,GRE3,SIF2,MBR1,TSL1,RCK2,GAL10,RSC9,IPK1,STR2,SSC1,MSK1,PHO23,ARO80,TPM2,DCS1,COR1,PRP4,RSE1,EXO1,THI21,RAD52,INH1,GRX1,CAR2,KIN82,PUP1,COX20,PRP12,RAD26,PCL7,RIM20,ALD2,ATP15,APA1,UBA3,PET123,EAP1,DLD3,ENO2,PEX19,CAP1,YAP1,PAP1,GLO4,AGX1,MRP8,DAK2,THI3,RPN6,RTG1,SWI5,HSC82,QCR9,BMH2,TSC13,POP5,VPS15,TRP4,MRPL16,TPM1,SEC12,DPP1,COQ4,ASP3-4,MSR1,HSP26,HAP2,CIT1,ADE8,AHC1,RSM18,MAL33,PAF1,COX4,TFS1,GPT2,AGP2,MUM2,MDM10,COQ3,NTH1,YMR31,YDC1,YPI1,TPS3,GUT2,TRM12,ATP16,MET22,ECM14,CIN5,UBP2,PRP45,RSF1,RIM4,YKU80,CYR1,HAP5,PFY1,YRM1,PYK2,GPX1,BUL1,GSY2,GID8,UBX6,GLK1,MRP51,DPL1,KTR4,GCY1,BMH1,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,CHO1,SSA1,NUT2,PRE1,GAD1,HEM15,MPT5,YKU70,AZF1,MRPL31,ARO10,SNF5,PUT3,HYP2,YPK2,HSM3,SDS24,YPC1,UBX5,CCP1,QCR2,CKI1,CYC7,RFA1,GLO2,LTP1,INO1,VPS45,ATP3,RSM28,ADE2,ATP17,VHS3,MDH3,TDH1,UGA2,CSR2,QRI8,GPI19,PHB1,SKN1,PDX3,GDB1,TDP1,STE24,SPO14,ARG4,RPN14,GAL11,QCR7,APA2,SDH4,NDE1,XRS2 GO:0030435 4 sporulation 105 0,0163 27 0,0338 0,0874939 E BDF1,AMA1,SHP1,PUP2,UBC4,UBX7,ERV14,PRB1,GTS1,AQY1,RIM21,ADE16,SGA1,RIM11,UBI4,RIM20,NEM1,EMI2,DIT1,BMH2,RIM4,UBX6,BMH1,RAS2,PRE1,SPO14,XRS2 GO:0005978 10,9,8 glycogen biosynthesis 11 0,0017 7 0,0088 0,0918046 E GLC3,PCL6,GLC8,GLG2,GLG1,PCL7,GSY2 GO:0007015 9 actin filament organization 63 0,0098 19 0,0238 0,1043867 E SAC6,ARC40,PPH22,LAS17,ARP3,SCD5,PBS2,RGA2,RHO3,LSB6,MSB3,ARP2,TPM2,SCP1,ENT1,TPM1,ENT3,IQG1,LSB5 GO:0005976 6 polysaccharide metabolism 53 0,0082 17 0,0213 0,1045622 E SHP1,GLC3,PCL6,GLC8,GLG2,PPG1,KRE9,GLG1,GPH1,SGA1,PCL7,BMH2,YPI1,GSY2,BMH1,SKN1,GDB1 GO:0044264 6,7 cellular polysaccharide metabolism 53 0,0082 17 0,0213 0,1045622 E SHP1,GLC3,PCL6,GLC8,GLG2,PPG1,KRE9,GLG1,GPH1,SGA1,PCL7,BMH2,YPI1,GSY2,BMH1,SKN1,GDB1 GO:0007005 6 mitochondrion organization and biogenesis 95 0,0147 25 0,0313 0,1057845 E MLC1,ARC40,TAZ1,ARC35,MDM31,ARC15,CRD1,DNM1,ARP3,RPO41,YME1,SAM50,HMI1,HSP78,ARP2,TPM2,NGR1,PRP12,FIS1,TPM1,MDM34,MDM10,BUL1,ARC19,MMM1 GO:0006094 9,10,8 gluconeogenesis 26 0,004 11 0,0138 0,115472 E TDH3,FYV10,RMD5,TDH2,VID30,UBC8,ENO1,GPM1,ENO2,GID8,TDH1 GO:0009117 6 nucleotide metabolism 90 0,0139 24 0,0301 0,1155515 E ZWF1,ATP2,STF2,ATP5,TKL2,QNS1,SOL4,ADE16,PNC1,BNA1,IDP3,POS5,INH1,ATP15,APA1,ADE8,GUT2,ATP16,ATP3,ADE2,ATP17,MDH3,APA2,NDE1 GO:0046903 5 secretion 209 0,0324 44 0,0551 0,1210794 E KIN1,SMY1,YPT1,SFT2,SNC1,BET3,KIN2,ERV14,KRE11,SEC17,GSF2,PEP12,SCD5,BET5,SEC6,KAR2,NCE102,GGA1,SEC9,SEC10,GOS1,VTI1,RHO3,SSA4,ENT5,SSA3,MSB3,TPM2,EXO70,VPS52,MYO3,TPM1,SEC12,SEC15,YPT7,ENT3,SSP120,SSA1,EMP46,VPS45,SSO1,SEC28,PEP7,SPO14 GO:0030154 3 cell differentiation 107 0,0166 27 0,0338 0,1211958 E BDF1,AMA1,SHP1,PUP2,UBC4,UBX7,ERV14,PRB1,GTS1,AQY1,RIM21,ADE16,SGA1,RIM11,UBI4,RIM20,NEM1,EMI2,DIT1,BMH2,RIM4,UBX6,BMH1,RAS2,PRE1,SPO14,XRS2 GO:0007275 2 development 373 0,0578 69 0,0865 0,130234 E BDF1,MLC1,SAC6,WHI5,SIP2,AMA1,RPD3,SHP1,PUP2,ATP2,YAF9,LAG1,UBC4,UBX7,CDC46,LAS17,SOD1,ERV14,LAG2,PRB1,GTS1,AQY1,RTG2,RIM21,ADE16,WHI4,SEC6,PNC1,SGA1,AVO2,RIM11,SLG1,SEC10,RGA2,RNY1,RHO3,RAD1,HST3,UBI4,THP1,SIF2,MUB1,TPM2,EXO70,RAD52,RIM20,NEM1,EMI2,SCP1,AFR1,AVO1,DIT1,MYO3,BMH2,TPM1,SEC15,RIM4,YKU80,CYR1,PFY1,UBX6,BMH1,RAS2,PRE1,MPT5,YKU70,PHB1,SPO14,XRS2 GO:0006100 8 tricarboxylic acid cycle intermediate metabolism 19 0,0029 9 0,0113 0,1765898 E LSC1,MDH1,KGD1,CIT2,CIT3,IDP3,CIT1,KGD2,MDH3 GO:0007569 5,4 cell aging 41 0,0064 14 0,0175 0,2018216 E SIP2,RPD3,ATP2,LAG1,SOD1,LAG2,GTS1,RTG2,PNC1,SCP1,CYR1,RAS2,MPT5,PHB1 GO:0044249 5 cellular biosynthesis 1105 0,1712 105 0,1316 0,2289697 D CBS2,MEF2,TDH3,ALD3,SHR5,COX15,FYV10,ALD6,PUT1,GLC3,AYR1,COX14,MRPL1,RIB4,PPH22,PTH1,PHO2,RMD5,MSY1,ATP2,STF2,ATP5,RSM23,TDH2,PBN1,MRPS18,QNS1,RIB5,RPL5,PCL6,ALG2,GLC8,COQ9,FAA1,BET4,VID30,GLG2,MRPL28,CIT2,PMT2,SWS2,ADE16,FMS1,GLG1,MRP20,GDH3,MSF1,FAD1,IST1,BNA1,FMT1,ETR1,UBC8,NAM2,ENO1,SLF1,ILS1,GPM1,ALG13,TPS1,BIO3,POS5,ECM32,TSL1,MSK1,THI21,INH1,PCL7,ALD2,ATP15,PET123,EAP1,ENO2,AGX1,MRP8,THI3,TRP4,MRPL16,MSR1,CIT1,ADE8,RSM18,COQ3,YMR31,TPS3,ATP16,MET22,GSY2,GID8,MRP51,KTR4,MST1,UGP1,HEM15,MRPL31,HYP2,ATP3,RSM28,ADE2,ATP17,VHS3,TDH1,GPI19,SKN1,ARG4 GO:0006090 7 pyruvate metabolism 37 0,0057 13 0,0163 0,2465906 E TDH3,FYV10,RMD5,TDH2,PDX1,VID30,UBC8,ENO1,GPM1,ENO2,PYK2,GID8,TDH1 GO:0019319 8,9 hexose biosynthesis 28 0,0043 11 0,0138 0,2471614 E TDH3,FYV10,RMD5,TDH2,VID30,UBC8,ENO1,GPM1,ENO2,GID8,TDH1 GO:0046364 7,8 monosaccharide biosynthesis 28 0,0043 11 0,0138 0,2471614 E TDH3,FYV10,RMD5,TDH2,VID30,UBC8,ENO1,GPM1,ENO2,GID8,TDH1 GO:0006121 9,11,8 mitochondrial electron transport, succinate to ubiquinone 4 0,0006 4 0,005 0,2526145 E SDH2,SDH1,SDH3,SDH4 GO:0042219 7,6 amino acid derivative catabolism 4 0,0006 4 0,005 0,2526145 E ALD3,FMS1,SRY1,ALD2 GO:0007265 7 Ras protein signal transduction 16 0,0025 8 0,01 0,2604273 E SHR5,TPK1,TPK2,BMH2,IRA2,CYR1,BMH1,RAS2 GO:0007568 3,4 aging 42 0,0065 14 0,0175 0,2657229 E SIP2,RPD3,ATP2,LAG1,SOD1,LAG2,GTS1,RTG2,PNC1,SCP1,CYR1,RAS2,MPT5,PHB1 GO:0006979 6,5 response to oxidative stress 52 0,0081 16 0,0201 0,2745723 E GLR1,ZWF1,MCR1,SOD1,ASK10,YBP1,NCE103,GRX2,POS5,GRX1,YAP1,CYR1,GPX1,GAD1,CCP1,UGA2 GO:0006139 5 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1500 0,2324 151 0,1892 0,2914222 D BDF1,TFG1,ADR1,MAL13,SRL3,USA1,POG1,REC114,RPD3,ZWF1,FYV6,PRP5,MED4,ECM2,ADY2,LEO1,YRR1,RPB7,PHO2,TAD3,SPT2,MSY1,ATP2,STF2,SNF4,YAF9,ATP5,LUC7,SSQ1,RAD59,PAP2,DDR48,CET1,TKL2,QNS1,SET3,CDC46,SPO11,RAD2,HYS2,ASK10,UFD1,RPH1,SNU71,SOL4,ISW1,CST6,UGA3,SWI1,MED8,RAD18,JSN1,PRI1,GTS1,MMS4,ADE16,MAG1,RAD50,MEC1,CCL1,RPO41,PNC1,INO4,CDC73,BNA1,MSL5,PAN3,YRF1-2,FMT1,IMP2prime,NAM2,MSC1,DHH1,TRA1,SET2,MCM3,CUS2,IDP3,DOA1,OAF1,EPL1,PHR1,RAD1,HST3,THP1,ISN1,POS5,RAD6,SWD2,SIF2,RSC9,MSK1,PHO23,ARO80,DCS1,PRP4,RSE1,EXO1,RAD52,INH1,PRP12,RAD26,ATP15,APA1,YAP1,PAP1,RTG1,SWI5,POP5,MSR1,HAP2,ADE8,AHC1,MAL33,PAF1,MUM2,GUT2,TRM12,ATP16,CIN5,PRP45,RSF1,RIM4,YKU80,HAP5,YRM1,RPB4,MUS81,MST1,UGP1,PRP22,NUT2,MPT5,YKU70,AZF1,SNF5,PUT3,HSM3,SDS24,RFA1,ATP3,ADE2,ATP17,MDH3,CSR2,QRI8,TDP1,GAL11,APA2,NDE1,XRS2 GO:0046907 7,5,6 intracellular transport 488 0,0756 84 0,1053 0,2925286 E PEX8,VPS29,ATG4,NPL3,YPT1,SFT2,SNC1,BET3,SKP1,VPS60,ERV14,KRE11,SEC17,PEX3,VPS73,VPS5,BRO1,PEX22,PEX25,ATG9,PEP12,SDS22,CSE1,BET5,SEC6,KAR2,SAM50,TOM6,MEX67,ECM10,GGA1,RAV2,VPS17,SEC9,VAC8,IMP1,SEC10,GOS1,VTI1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,THP1,TIM21,SSC1,VPS38,YPT52,EXO70,VPS30,ATG7,VPS52,PEX19,PAP1,ATG12,MRL1,ATG19,PEP8,VPS15,SEC12,SEC15,YPT7,ENT3,PEX12,MTR10,PFY1,MAD1,ASM4,RPB4,SSA1,MPT5,PEP1,VPS70,EMP46,VPS21,BSD2,VPS45,SSO1,SEC28,CRM1,VPS8,PEP7 GO:0006944 3 membrane fusion 58 0,009 17 0,0213 0,3334851 E SNC1,SEC17,VAM6,SEC6,SEC9,VAC8,SEC10,GOS1,VTI1,EXO70,SEC15,YPT7,PBI2,CLN3,NYV1,SSO1,PEP7 GO:0019320 8,9 hexose catabolism 29 0,0045 11 0,0138 0,3494359 E PFK26,TDH3,ZWF1,TDH2,TKL2,PFK27,SOL4,ENO1,GPM1,ENO2,TDH1 GO:0006007 9,1 glucose catabolism 29 0,0045 11 0,0138 0,3494359 E PFK26,TDH3,ZWF1,TDH2,TKL2,PFK27,SOL4,ENO1,GPM1,ENO2,TDH1 GO:0009065 8,9 glutamine family amino acid catabolism 13 0,002 7 0,0088 0,3673553 E PUT1,ASP3-3,CAR2,ASP3-4,GAD1,PUT3,UGA2 GO:0009267 5,6 cellular response to starvation 13 0,002 7 0,0088 0,3673553 E SIP2,PHO2,PRB1,SIP5,ASP3-3,ASP3-4,DPL1 GO:0042594 5 response to starvation 13 0,002 7 0,0088 0,3673553 E SIP2,PHO2,PRB1,SIP5,ASP3-3,ASP3-4,DPL1 GO:0045045 5,6 secretory pathway 202 0,0313 41 0,0514 0,4131009 E KIN1,SMY1,YPT1,SFT2,SNC1,BET3,KIN2,ERV14,KRE11,SEC17,GSF2,PEP12,BET5,SEC6,KAR2,GGA1,SEC9,SEC10,GOS1,VTI1,RHO3,SSA4,ENT5,SSA3,MSB3,TPM2,EXO70,VPS52,MYO3,TPM1,SEC12,SEC15,YPT7,ENT3,SSA1,EMP46,VPS45,SSO1,SEC28,PEP7,SPO14 GO:0006800 5 oxygen and reactive oxygen species metabolism 54 0,0084 16 0,0201 0,430698 E GLR1,ZWF1,MCR1,SOD1,ASK10,YBP1,NCE103,GRX2,POS5,GRX1,YAP1,CYR1,GPX1,GAD1,CCP1,UGA2 GO:0006906 6,4,7 vesicle fusion 30 0,0046 11 0,0138 0,484158 E SNC1,SEC6,SEC9,SEC10,GOS1,VTI1,EXO70,SEC15,NYV1,SSO1,PEP7 GO:0046165 6 alcohol biosynthesis 30 0,0046 11 0,0138 0,484158 E TDH3,FYV10,RMD5,TDH2,VID30,UBC8,ENO1,GPM1,ENO2,GID8,TDH1 GO:0005991 8 trehalose metabolism 7 0,0011 5 0,0063 0,5022998 E NTH2,TPS1,TSL1,NTH1,TPS3 GO:0005980 10,9 glycogen catabolism 7 0,0011 5 0,0063 0,5022998 E PCL6,GPH1,SGA1,PCL7,GDB1 GO:0051649 6,5 establishment of cellular localization 498 0,0772 84 0,1053 0,5278409 E PEX8,VPS29,ATG4,NPL3,YPT1,SFT2,SNC1,BET3,SKP1,VPS60,ERV14,KRE11,SEC17,PEX3,VPS73,VPS5,BRO1,PEX22,PEX25,ATG9,PEP12,SDS22,CSE1,BET5,SEC6,KAR2,SAM50,TOM6,MEX67,ECM10,GGA1,RAV2,VPS17,SEC9,VAC8,IMP1,SEC10,GOS1,VTI1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,THP1,TIM21,SSC1,VPS38,YPT52,EXO70,VPS30,ATG7,VPS52,PEX19,PAP1,ATG12,MRL1,ATG19,PEP8,VPS15,SEC12,SEC15,YPT7,ENT3,PEX12,MTR10,PFY1,MAD1,ASM4,RPB4,SSA1,MPT5,PEP1,VPS70,EMP46,VPS21,BSD2,VPS45,SSO1,SEC28,CRM1,VPS8,PEP7 GO:0048610 4 reproductive cellular physiological process 192 0,0297 39 0,0489 0,5433465 E BDF1,AMA1,POG1,SHP1,PUP2,CMP2,STE18,OPY2,UBC4,ERV14,GRR1,STE11,MDG1,PRM5,GTS1,AQY1,RIM21,ADE16,KAR2,SGA1,RIM11,RGA2,FAR10,UBI4,PTP2,CNB1,NEM1,EMI2,AFR1,PRM8,DIT1,BMH2,STE5,BMH1,RAS2,PRE1,MPT5,FAR11,SPO14 GO:0050876 3 reproductive physiological process 192 0,0297 39 0,0489 0,5433465 E BDF1,AMA1,POG1,SHP1,PUP2,CMP2,STE18,OPY2,UBC4,ERV14,GRR1,STE11,MDG1,PRM5,GTS1,AQY1,RIM21,ADE16,KAR2,SGA1,RIM11,RGA2,FAR10,UBI4,PTP2,CNB1,NEM1,EMI2,AFR1,PRM8,DIT1,BMH2,STE5,BMH1,RAS2,PRE1,MPT5,FAR11,SPO14 GO:0007166 5 cell surface receptor linked signal transduction 40 0,0062 13 0,0163 0,5630814 E STE18,STE11,MDG1,PBS2,RGA2,SSK2,PTP2,RCK2,LEM3,AFR1,STE5,CYR1,RAS2 GO:0009058 4 biosynthesis 1184 0,1835 117 0,1466 0,6035639 D CBS2,MEF2,TDH3,ALD3,SHR5,TAZ1,COX15,FYV10,ALD6,PUT1,GLC3,AYR1,COX14,MRPL1,RIB4,PPH22,PTH1,PHO2,RMD5,MSY1,ATP2,STF2,ATP5,RSM23,LAG1,SCT1,OSH6,MCR1,TDH2,PBN1,MRPS18,QNS1,RIB5,RPL5,ERG9,CRD1,CSG2,PCL6,ALG2,GLC8,COQ9,FAA1,BET4,VID30,GLG2,MRPL28,CIT2,PMT2,SWS2,ADE16,FMS1,GLG1,MRP20,GDH3,MSF1,FAD1,IST1,INO4,BNA1,FMT1,ETR1,UBC8,NAM2,ENO1,SLF1,ILS1,GPM1,ALG13,TPS1,BIO3,POS5,ECM32,TSL1,MSK1,THI21,INH1,PCL7,ALD2,ATP15,PET123,EAP1,ENO2,AGX1,MRP8,THI3,TRP4,MRPL16,MSR1,CIT1,ADE8,RSM18,GPT2,COQ3,YMR31,TPS3,ATP16,MET22,GSY2,GID8,MRP51,KTR4,MST1,UGP1,CHO1,HEM15,MRPL31,HYP2,CKI1,ATP3,RSM28,ADE2,ATP17,VHS3,TDH1,GPI19,SKN1,ARG4 GO:0007032 6 endosome organization and biogenesis 36 0,0056 12 0,015 0,7074493 E VPS29,SFT2,VPS60,VPS5,VPS17,VTI1,ENT5,VPS38,VPS52,PEP8,ENT3,VPS8 GO:0016197 8,7,6 endosome transport 36 0,0056 12 0,015 0,7074493 E VPS29,SFT2,VPS60,VPS5,VPS17,VTI1,ENT5,VPS38,VPS52,PEP8,ENT3,VPS8 GO:0008219 4 cell death 46 0,0071 14 0,0175 0,7156079 E SIP2,RPD3,ATP2,LAG1,SOD1,LAG2,GTS1,RTG2,PNC1,SCP1,CYR1,RAS2,MPT5,PHB1 GO:0006109 6,5 regulation of carbohydrate metabolism 27 0,0042 10 0,0125 0,7919494 E ADR1,FYV10,RMD5,PCL6,VID30,UBC8,PCL7,HAP2,HAP5,GID8 GO:0009108 7 coenzyme biosynthesis 57 0,0088 16 0,0201 0,7995893 E ATP2,STF2,ATP5,QNS1,COQ9,FMS1,FAD1,BNA1,POS5,INH1,ATP15,COQ3,ATP16,ATP3,ATP17,VHS3 GO:0016265 3 death 47 0,0073 14 0,0175 0,8945032 E SIP2,RPD3,ATP2,LAG1,SOD1,LAG2,GTS1,RTG2,PNC1,SCP1,CYR1,RAS2,MPT5,PHB1 GO:0007031 6 peroxisome organization and biogenesis 37 0,0057 12 0,015 0,9187979 E PEX8,ADR1,PEX2,SNF4,PEX3,PEX22,PEX25,OAF1,PEX5,PEX29,PEX19,PEX12 GO:0006897 6,7 endocytosis 69 0,0107 18 0,0226 0,9663466 E MLC1,SAC6,SNC1,LAS17,SCD5,SLG1,YPT52,YAP1801,ENT1,MYO3,ENT3,RCY1,YPK1,SDS24,VPS21,EDE1,LSB5,CLC1 GO:0000087 6 M phase of mitotic cell cycle 148 0,0229 7 0,0088 0,9740797 D BUB3,PPH22,PAP2,CCL1,MPS1,APC9,MAD1 GO:0006644 7,8 phospholipid metabolism 79 0,0122 13 0,0163 1 E TAZ1,AYR1,SCT1,PBN1,LPP1,INO4,LSB6,DPP1,GPT2,CHO1,CKI1,GPI19,SPO14 GO:0050790 3 regulation of enzyme activity 25 0,0039 6 0,0075 1 E SIC1,PBS2,SSK2,PTP2,RAS2,CLN3 GO:0045454 5 cell redox homeostasis 10 0,0015 4 0,005 1 E PRX1,AHP1,GRX2,GRX1 GO:0000320 6 re-entry into mitotic cell cycle 3 0,0005 2 0,0025 1 E POG1,MPT5 GO:0000055 12,9,10,11 ribosomal large subunit export from nucleus 7 0,0011 1 0,0013 1 E CRM1 GO:0043170 4 macromolecule metabolism 2511 0,3891 323 0,4048 1 E SSA2,BDF1,GIP2,SCL1,CBS2,PGM2,MEF2,ADR1,SIP2,MAL13,PFK26,AMA1,SDH2,USA1,ULA1,TDH3,PRE7,UBR1,RPN11,YMR1,REC114,RPN7,RPD3,ZWF1,RPT1,FYV6,LSC1,SHR5,CNE1,PRP5,YPR1,DOG2,ECM2,COX15,SHP1,MDJ1,HSP82,FYV10,ADY2,LEO1,GLC3,PUP2,COX14,MRPL1,SIZ1,PPH22,PTH1,YPT1,PRE10,TAD3,RPT2,RMD5,MSY1,YAF9,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,SSQ1,RAD59,PAP2,ATP10,PAI3,DDR48,UBC4,CET1,TDH2,TKL2,PBN1,MRPS18,DDI1,PFK27,SET3,UBX7,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,LAS17,RAD2,RUP1,NTA1,HYS2,MAL12,PCL6,KNS1,NPL4,ALG2,UBP15,GLC8,SSE1,FAA1,GND2,CBP4,UFD1,GRR1,BET4,STE11,RPH1,PRB1,GSF2,SNU71,AHA1,XYL2,SOL4,VID30,RPN9,UBP6,ISW1,CST6,AOS1,GLG2,MRPL28,TPK1,FBP26,BRO1,SWI1,RAD18,JSN1,STI1,DLD1,PRI1,CIT2,PPG1,PMT2,SWS2,HXK1,MMS4,SSE2,UFD2,MAG1,SDH1,RAD50,KRE9,MEC1,CIT3,GLG1,MRP20,GPH1,DAP2,MSF1,PNC1,SAM50,MPD1,IST1,CDC73,ECM10,SGA1,MSL5,PAN3,YRF1-2,FMT1,IMP2prime,RIM11,UBC8,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,TRA1,XKS1,IMP1,SET2,ENO1,PSK2,MCM3,CPR6,PPM1,CUS2,IDP3,SLF1,DOA1,ILS1,TPK2,GPM1,SSK2,CAP2,HSP78,EPL1,HCH1,PHR1,SSA4,APC9,RAD1,HST3,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,THP1,TPS1,PTP2,GAL7,MRK1,RAD6,RPN3,CMK1,SWD2,ECM32,GRE3,SIF2,TSL1,RCK2,GAL10,RSC9,IPK1,SSC1,MSK1,PHO23,TPM2,DCS1,PRP4,RSE1,EXO1,RAD52,KIN82,PUP1,COX20,PRP12,RAD26,PCL7,RIM20,UBA3,PET123,EAP1,ENO2,PEX19,CAP1,PAP1,GLO4,MRP8,RPN6,HSC82,BMH2,POP5,VPS15,MRPL16,TPM1,SEC12,MSR1,HSP26,HAP2,CIT1,AHC1,RSM18,MAL33,PAF1,TFS1,MUM2,MDM10,NTH1,YMR31,YPI1,TPS3,GUT2,TRM12,ECM14,UBP2,RIM4,YKU80,HAP5,PFY1,BUL1,GSY2,GID8,UBX6,GLK1,MRP51,KTR4,GCY1,BMH1,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,SSA1,PRE1,MPT5,YKU70,MRPL31,YTA7,SNF5,HYP2,YPK2,ARA1,HSM3,SDS24,UBX5,LAP4,RFA1,GLO2,LTP1,INO1,VPS45,RSM28,MDH3,TDH1,QRI8,GPI19,PHB1,SKN1,GDB1,TDP1,STE24,RPN14,QCR7,SDH4,XRS2 GO:0006882 8,9 zinc ion homeostasis 10 0,0015 3 0,0038 1 E SOD1,COT1,IZH3 GO:0042402 7,8 biogenic amine catabolism 3 0,0005 3 0,0038 1 E ALD3,FMS1,ALD2 GO:0051261 7 protein depolymerization 8 0,0012 3 0,0038 1 E AIP1,CAP2,CAP1 GO:0045471 7 response to ethanol 1 0,0002 1 0,0013 1 E ASR1 GO:0048518 3 positive regulation of biological process 78 0,0121 13 0,0163 1 E RPD3,YRR1,UGA3,INO4,PBS2,OAF1,SSK2,ARO80,PRP45,YRM1,RAS2,MPT5,PUT3 GO:0009156 8,9 ribonucleoside monophosphate biosynthesis 15 0,0023 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0000245 8,10,12 spliceosome assembly 15 0,0023 3 0,0038 1 E PRP5,LUC7,RSE1 GO:0046834 7,8 lipid phosphorylation 4 0,0006 1 0,0013 1 E LSB6 GO:0000051 5,4 urea cycle intermediate metabolism 15 0,0023 2 0,0025 1 E CAR2,ARG4 GO:0046474 9,8,10 glycerophospholipid biosynthesis 34 0,0053 5 0,0063 1 E AYR1,PBN1,CHO1,CKI1,GPI19 GO:0009124 7,8 nucleoside monophosphate biosynthesis 17 0,0026 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0019740 5 nitrogen utilization 14 0,0022 4 0,005 1 E ADY2,VID30,NPR1,UGA3 GO:0006769 9,8 nicotinamide metabolism 31 0,0048 10 0,0125 1 E ZWF1,TKL2,QNS1,SOL4,BNA1,IDP3,POS5,GUT2,MDH3,NDE1 GO:0050789 2 regulation of biological process 597 0,0925 92 0,1153 1 E ADR1,MAL13,PFK26,BUB3,POG1,RPD3,FYV10,COX14,YRR1,PPH22,SPT2,RMD5,SNF4,YAF9,SIC1,OPY2,PFK27,CDC46,SKP1,PCL6,GRR1,RPH1,VID30,NPR1,UGA3,PRX1,JSN1,GTS1,MEC1,CCL1,PNC1,INO4,MPS1,AHP1,AVO2,CDC37,UBC8,DHH1,RAV2,PBS2,TRA1,SET2,BCK2,SLF1,GRX2,OAF1,SSK2,CAP2,EPL1,APC9,HST3,FAR10,PTP2,MRK1,TOR1,ECM32,SIF2,RSC9,MUB1,ARO80,DCS1,GRX1,NGR1,PCL7,EAP1,AFR1,CAP1,AVO1,SWI5,BMH2,HAP2,MAL33,TFS1,CIN5,PRP45,YKU80,CYR1,HAP5,YRM1,MAD1,GID8,BMH1,PBI2,RAS2,MPT5,YKU70,AZF1,FAR11,PUT3,CLN3,CSR2,PHB1 GO:0006829 9,1 zinc ion transport 6 0,0009 1 0,0013 1 E COT1 GO:0006267 9 pre-replicative complex formation and maintenance 13 0,002 2 0,0025 1 E CDC46,MCM3 GO:0046520 9,8,10 sphingoid biosynthesis 3 0,0005 1 0,0013 1 E LAG1 GO:0045046 11,8,9,7,10 protein import into peroxisome membrane 2 0,0003 2 0,0025 1 E PEX3,PEX19 GO:0019563 8 glycerol catabolism 3 0,0005 1 0,0013 1 E DAK2 GO:0051252 7 regulation of RNA metabolism 24 0,0037 4 0,005 1 E JSN1,DHH1,DCS1,MPT5 GO:0006639 7,6,8 acylglycerol metabolism 4 0,0006 1 0,0013 1 E TGL4 GO:0009205 9 purine ribonucleoside triphosphate metabolism 22 0,0034 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0006536 8,9 glutamate metabolism 16 0,0025 6 0,0075 1 E PUT1,CIT2,GDH3,CIT1,GAD1,UGA2 GO:0006766 5 vitamin metabolism 74 0,0115 18 0,0226 1 E ZWF1,RIB4,CAT2,TKL2,QNS1,RIB5,SOL4,PNC1,FAD1,BNA1,IDP3,BIO3,POS5,THI21,THI3,GUT2,MDH3,NDE1 GO:0008104 4 protein localization 285 0,0442 51 0,0639 1 E PEX8,ATG4,SHR5,SNX41,UFD1,PEX3,VPS73,VPS5,PEX22,PEX25,ATG9,SCD5,SDS22,CSE1,KAR2,SAM50,TOM6,ECM10,NCE102,VAC8,IMP1,ERD2,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,TIM21,SSC1,YPT52,VPS30,ATG7,PEX19,ATG12,ATG19,PEP8,RTG1,VPS15,ENT3,PEX12,MTR10,SSP120,ASM4,SSA1,MPT5,PEP1,VPS70,VPS21,BSD2,CRM1 GO:0019655 7,9 ethanol fermentation 5 0,0008 1 0,0013 1 E NDE1 GO:0045893 9 positive regulation of transcription, DNA-dependent 59 0,0091 9 0,0113 1 E RPD3,YRR1,UGA3,INO4,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0048511 3 rhythmic process 1 0,0002 1 0,0013 1 E GTS1 GO:0007323 9 peptide pheromone maturation 8 0,0012 1 0,0013 1 E STE24 GO:0005998 9,1 xylulose catabolism 1 0,0002 1 0,0013 1 E XKS1 GO:0000272 6,7 polysaccharide catabolism 12 0,0019 5 0,0063 1 E PCL6,GPH1,SGA1,PCL7,GDB1 GO:0006020 8,9 myo-inositol metabolism 6 0,0009 2 0,0025 1 E IPK1,INO1 GO:0017062 9 cytochrome bc(1) complex assembly 1 0,0002 1 0,0013 1 E QCR7 GO:0048622 5 reproductive sporulation 92 0,0143 21 0,0263 1 E BDF1,AMA1,SHP1,PUP2,UBC4,ERV14,GTS1,AQY1,RIM21,ADE16,SGA1,RIM11,UBI4,NEM1,EMI2,DIT1,BMH2,BMH1,RAS2,PRE1,SPO14 GO:0009636 6 response to toxin 5 0,0008 2 0,0025 1 E GLO4,GLO2 GO:0007050 7 cell cycle arrest 11 0,0017 4 0,005 1 E OPY2,GRR1,FAR10,FAR11 GO:0009084 8,9 glutamine family amino acid biosynthesis 24 0,0037 5 0,0063 1 E PUT1,CIT2,GDH3,CIT1,ARG4 GO:0006011 9,7,10 UDP-glucose metabolism 1 0,0002 1 0,0013 1 E UGP1 GO:0006812 6,7 cation transport 89 0,0138 15 0,0188 1 E ISA2,MTM1,ATP2,STF2,PMP3,ATP5,COT1,ENA2,SCO2,INH1,ATP15,ATP16,BSD2,ATP3,ATP17 GO:0019255 9,1 glucose 1-phosphate metabolism 2 0,0003 1 0,0013 1 E PGM2 GO:0009161 8 ribonucleoside monophosphate metabolism 17 0,0026 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0000059 11,9,8,10 protein import into nucleus, docking 4 0,0006 1 0,0013 1 E ASM4 GO:0046160 8,7 heme a metabolism 4 0,0006 1 0,0013 1 E COX15 GO:0000735 10,7 removal of nonhomologous ends 4 0,0006 1 0,0013 1 E RAD1 GO:0044267 6 cellular protein metabolism 1400 0,2169 175 0,2193 1 E SSA2,GIP2,SCL1,CBS2,MEF2,SIP2,ULA1,PRE7,UBR1,RPN11,RPN7,RPD3,RPT1,SHR5,CNE1,PRP5,COX15,SHP1,MDJ1,HSP82,LEO1,PUP2,COX14,MRPL1,SIZ1,PPH22,PTH1,YPT1,PRE10,RPT2,MSY1,RPN5,LUC7,RSM23,RPT3,ASI2,ATP10,UBC4,PBN1,MRPS18,DDI1,SET3,UBX7,SLT2,PKH2,AIP1,SKP1,RPL5,RUP1,NTA1,KNS1,NPL4,ALG2,UBP15,SSE1,FAA1,CBP4,UFD1,GRR1,BET4,STE11,GSF2,AHA1,VID30,RPN9,UBP6,AOS1,MRPL28,TPK1,BRO1,STI1,PPG1,PMT2,SWS2,SSE2,UFD2,MRP20,DAP2,MSF1,SAM50,MPD1,IST1,CDC73,ECM10,FMT1,RIM11,UBC8,NAM2,HSP104,RAV2,PBS2,TRA1,IMP1,SET2,PSK2,CPR6,PPM1,SLF1,DOA1,ILS1,TPK2,SSK2,CAP2,HSP78,EPL1,HCH1,SSA4,APC9,SSA3,OCT1,ALG13,UBI4,FMC1,PTP2,MRK1,RAD6,RPN3,CMK1,SWD2,ECM32,SIF2,RCK2,SSC1,MSK1,RSE1,RAD52,KIN82,PUP1,COX20,RIM20,UBA3,PET123,EAP1,PEX19,CAP1,MRP8,RPN6,HSC82,VPS15,MRPL16,SEC12,MSR1,HSP26,AHC1,RSM18,PAF1,TFS1,MDM10,YMR31,YPI1,ECM14,UBP2,BUL1,UBX6,MRP51,KTR4,MST1,PBI2,UGP1,YPK1,SSA1,PRE1,MRPL31,HYP2,YPK2,UBX5,LTP1,VPS45,RSM28,QRI8,GPI19,PHB1,STE24,RPN14,QCR7 GO:0043487 8 regulation of RNA stability 22 0,0034 4 0,005 1 E JSN1,DHH1,DCS1,MPT5 GO:0046102 9 inosine metabolism 1 0,0002 1 0,0013 1 E ISN1 GO:0009651 6 response to salt stress 12 0,0019 3 0,0038 1 E MET22,CIN5,GCY1 GO:0042440 5 pigment metabolism 15 0,0023 3 0,0038 1 E COX15,HMX1,HEM15 GO:0018318 11,1 protein amino acid palmitoylation 3 0,0005 1 0,0013 1 E SHR5 GO:0019538 5 protein metabolism 1424 0,2206 181 0,2268 1 E SSA2,GIP2,SCL1,CBS2,MEF2,SIP2,AMA1,ULA1,PRE7,UBR1,RPN11,RPN7,RPD3,RPT1,SHR5,CNE1,PRP5,COX15,SHP1,MDJ1,HSP82,LEO1,PUP2,COX14,MRPL1,SIZ1,PPH22,PTH1,YPT1,PRE10,RPT2,MSY1,RPN5,LUC7,RSM23,RPT3,ASI2,ATP10,PAI3,UBC4,PBN1,MRPS18,DDI1,SET3,UBX7,SLT2,PKH2,AIP1,SKP1,RPL5,RUP1,NTA1,KNS1,NPL4,ALG2,UBP15,SSE1,FAA1,CBP4,UFD1,GRR1,BET4,STE11,PRB1,GSF2,AHA1,VID30,RPN9,UBP6,AOS1,MRPL28,TPK1,BRO1,STI1,PPG1,PMT2,SWS2,SSE2,UFD2,MRP20,DAP2,MSF1,SAM50,MPD1,IST1,CDC73,ECM10,FMT1,RIM11,UBC8,NAM2,HSP104,RAV2,PBS2,TRA1,IMP1,SET2,PSK2,CPR6,PPM1,SLF1,DOA1,ILS1,TPK2,SSK2,CAP2,HSP78,EPL1,HCH1,SSA4,APC9,SSA3,OCT1,ALG13,UBI4,FMC1,PTP2,MRK1,RAD6,RPN3,CMK1,SWD2,ECM32,SIF2,RCK2,SSC1,MSK1,RSE1,RAD52,KIN82,PUP1,COX20,RIM20,UBA3,PET123,EAP1,PEX19,CAP1,MRP8,RPN6,HSC82,VPS15,MRPL16,SEC12,MSR1,HSP26,AHC1,RSM18,PAF1,TFS1,MDM10,YMR31,YPI1,ECM14,UBP2,BUL1,UBX6,MRP51,KTR4,MST1,PBI2,UGP1,PRP22,YPK1,SSA1,PRE1,MRPL31,YTA7,HYP2,YPK2,UBX5,LAP4,LTP1,VPS45,RSM28,QRI8,GPI19,PHB1,STE24,RPN14,QCR7 GO:0042147 9,8,7 retrograde transport, endosome to Golgi 10 0,0015 5 0,0063 1 E VPS29,VPS5,VPS17,VPS52,PEP8 GO:0045761 9,10,5 regulation of adenylate cyclase activity 1 0,0002 1 0,0013 1 E RAS2 GO:0006520 6,7 amino acid metabolism 182 0,0282 27 0,0338 1 E ARO9,ALD3,PUT1,PHO2,MSY1,CIT2,GDH3,ASP3-3,FMT1,NAM2,CHA1,MSK1,ARO80,CAR2,ALD2,AGX1,TRP4,ASP3-4,MSR1,CIT1,MET22,MST1,GAD1,ARO10,PUT3,UGA2,ARG4 GO:0019439 6 aromatic compound catabolism 3 0,0005 2 0,0025 1 E ARO80,ARO10 GO:0009306 6 protein secretion 9 0,0014 3 0,0038 1 E SCD5,NCE102,SSP120 GO:0006635 8,9 fatty acid beta-oxidation 9 0,0014 3 0,0038 1 E FOX2,IDP3,MDH3 GO:0007010 6 cytoskeleton organization and biogenesis 290 0,0449 42 0,0526 1 E MLC1,SAC6,ARC40,ARC35,PPH22,ARC15,HUA1,AIP1,LAS17,ERV14,ARP3,NUD1,BBC1,SCD5,SEC6,SLG1,PBS2,SEC10,RGA2,SSK2,CAP2,RHO3,APC9,LSB6,MSB3,THP1,ARP2,TPM2,EXO70,SPC105,VPS52,SCP1,CAP1,ENT1,MYO3,TPM1,SEC15,ENT3,PFY1,IQG1,ARC19,LSB5 GO:0006497 9,8 protein lipidation 36 0,0056 5 0,0063 1 E SHR5,PBN1,FAA1,BET4,GPI19 GO:0007089 8,6 traversing start control point of mitotic cell cycle 5 0,0008 1 0,0013 1 E GID8 GO:0006430 10,11,9 lysyl-tRNA aminoacylation 2 0,0003 1 0,0013 1 E MSK1 GO:0016043 4 cell organization and biogenesis 1473 0,2282 206 0,2581 1 E BDF1,PEX8,VPS29,MLC1,SAC6,ADR1,WHI5,ARC40,ATG4,RPD3,NPL3,TAZ1,ECM2,PEX2,LEO1,ARC35,PPH22,MDM31,ARC15,YPT1,HUA1,SFT2,SNC1,ECM21,SNF4,YAF9,ECM18,RAD59,PAP2,BET3,SET3,CDC46,SLT2,PKH2,AIP1,SKP1,RPL5,LAS17,CRD1,VPS60,ERV14,KRE11,DNM1,MTL1,ARP3,SEC17,PEX3,VPS73,ISW1,VPS5,EST3,ECM4,BRO1,SWI1,NUD1,VAM6,GTS1,PEX22,PEX25,LRE1,BBC1,ATG9,PEP12,RAD50,KRE9,FMP45,MEC1,SCD5,TUS1,WHI4,SDS22,CSE1,RPO41,BET5,SEC6,KAR2,PNC1,YME1,TAX4,SAM50,TOM6,MEX67,CDC73,ECM10,MPS1,YRF1-2,AVO2,MYO4,CDC37,GGA1,SLG1,RAV2,PBS2,VPS17,HMI1,TRA1,SEC9,VAC8,IMP1,SEC10,GOS1,VTI1,SET2,OAF1,RGA2,SSK2,CAP2,HSP78,EPL1,PEX5,RNY1,RHO3,SSA4,ENT5,APC9,HST3,LSB6,SSA3,OCT1,MSB3,THP1,TIM21,RAD6,SWD2,TOR1,SIF2,ARP2,RSC9,SSC1,PHO23,TPM2,VPS38,YPT52,EXO70,VPS30,RAD52,SPC105,NGR1,CNB1,PRP12,ATG7,PEX29,VPS52,NEM1,SBE22,SCP1,PEX19,AFR1,CAP1,PAP1,AVO1,ATG12,ENT1,MRL1,ATG19,MYO3,PEP8,FIS1,POP5,VPS15,TPM1,SEC12,MDM34,AHC1,SEC15,PAF1,YPT7,ENT3,ECM30,MDM10,ECM14,ROT1,PEX12,YKU80,MTR10,PFY1,IQG1,BUL1,MAD1,ASM4,RPB4,PBI2,SSA1,MPT5,YKU70,SNF5,PEP1,ARC19,VPS70,CLN3,EMP46,SSD1,VPS21,BSD2,MMM1,VPS45,SSO1,SEC28,CRM1,VPS8,CSR2,QRI8,PEP7,SKN1,LSB5,XRS2 GO:0008645 7,8 hexose transport 21 0,0033 5 0,0063 1 E HXT6,HXT16,HXT5,HXT7,HXT13 GO:0005992 9,8 trehalose biosynthesis 4 0,0006 3 0,0038 1 E TPS1,TSL1,TPS3 GO:0043101 6 purine salvage 7 0,0011 1 0,0013 1 E ISN1 GO:0006268 9 DNA unwinding during replication 12 0,0019 3 0,0038 1 E CDC46,MCM3,RFA1 GO:0006077 9,1 beta-1,6 glucan metabolism 5 0,0008 2 0,0025 1 E KRE9,SKN1 GO:0000737 7,8 DNA catabolism, endonucleolytic 9 0,0014 4 0,005 1 E REC114,SPO11,RAD50,XRS2 GO:0010033 6 response to organic substance 1 0,0002 1 0,0013 1 E ASR1 GO:0000754 7,5 adaptation to pheromone during conjugation with cellular fusion 13 0,002 4 0,005 1 E POG1,CMP2,CNB1,MPT5 GO:0009083 8,9 branched chain family amino acid catabolism 2 0,0003 1 0,0013 1 E ARO10 GO:0051321 5 meiotic cell cycle 129 0,02 22 0,0276 1 E BDF1,ZIP1,AMA1,REC114,ADY2,SET3,SPO11,MMS4,RAD50,MEC1,CST9,MSC1,TOR1,SIF2,RCK2,RAD52,WTM1,RIM4,CYR1,MUS81,SDS24,XRS2 GO:0008064 10,6,7 regulation of actin polymerization and/or depolymerization 3 0,0005 2 0,0025 1 E CAP2,CAP1 GO:0000165 7 MAPKKK cascade 17 0,0026 4 0,005 1 E PKH2,PBS2,SSK2,PTP2 GO:0001403 4 invasive growth (sensu Saccharomyces) 32 0,005 6 0,0075 1 E STE11,RIM21,RGA2,RIM20,STE5,DIA3 GO:0006113 7 fermentation 16 0,0025 3 0,0038 1 E ADH2,ACS1,NDE1 GO:0015936 8 coenzyme A metabolism 7 0,0011 1 0,0013 1 E VHS3 GO:0044272 6 sulfur compound biosynthesis 15 0,0023 2 0,0025 1 E BIO3,MET22 GO:0030150 11,9,7,10,8 protein import into mitochondrial matrix 21 0,0033 4 0,005 1 E TOM6,HSP78,TIM21,SSC1 GO:0006519 5 amino acid and derivative metabolism 197 0,0305 30 0,0376 1 E ARO9,ALD3,PUT1,PHO2,MSY1,CAT2,CIT2,FMS1,GDH3,ASP3-3,FMT1,NAM2,SRY1,CHA1,MSK1,ARO80,CAR2,ALD2,AGX1,TRP4,ASP3-4,MSR1,CIT1,MET22,MST1,GAD1,ARO10,PUT3,UGA2,ARG4 GO:0042167 8,7 heme catabolism 1 0,0002 1 0,0013 1 E HMX1 GO:0007040 7 lysosome organization and biogenesis 1 0,0002 1 0,0013 1 E VTI1 GO:0043039 8,9 tRNA aminoacylation 30 0,0046 6 0,0075 1 E MSY1,FMT1,NAM2,MSK1,MSR1,MST1 GO:0016226 7 iron-sulfur cluster assembly 9 0,0014 2 0,0025 1 E ISU1,QCR9 GO:0007533 5 mating type switching 17 0,0026 3 0,0038 1 E RAD1,RAD52,YKU80 GO:0045005 9 maintenance of fidelity during DNA-dependent DNA replication 20 0,0031 3 0,0038 1 E HYS2,EXO1,HSM3 GO:0043405 6 regulation of MAPK activity 6 0,0009 2 0,0025 1 E PBS2,PTP2 GO:0008213 8 protein amino acid alkylation 20 0,0031 6 0,0075 1 E LEO1,CDC73,SET2,PPM1,SWD2,PAF1 GO:0015031 5,6 protein transport 245 0,038 43 0,0539 1 E PEX8,ATG4,SNX41,UFD1,PEX3,VPS73,PEX22,PEX25,ATG9,SDS22,CSE1,KAR2,SAM50,TOM6,ECM10,VAC8,IMP1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,TIM21,SSC1,YPT52,VPS30,ATG7,PEX19,ATG12,ATG19,VPS15,ENT3,PEX12,MTR10,ASM4,SSA1,MPT5,PEP1,VPS70,VPS21,BSD2,CRM1 GO:0000186 8,7 activation of MAPKK activity 2 0,0003 1 0,0013 1 E SSK2 GO:0009746 7,6 response to hexose stimulus 5 0,0008 2 0,0025 1 E SNF3,RGT2 GO:0005984 7 disaccharide metabolism 28 0,0043 6 0,0075 1 E NTH2,MAL12,TPS1,TSL1,NTH1,TPS3 GO:0009415 5 response to water 10 0,0015 2 0,0025 1 E SIP18,STF2 GO:0001323 7,6 age-dependent general metabolic decline during chronological cell aging 7 0,0011 2 0,0025 1 E SOD1,CYR1 GO:0009064 7,8 glutamine family amino acid metabolism 43 0,0067 11 0,0138 1 E PUT1,CIT2,GDH3,ASP3-3,CAR2,ASP3-4,CIT1,GAD1,PUT3,UGA2,ARG4 GO:0001307 8,7 extrachromosomal circular DNA accumulation during replicative cell aging 1 0,0002 1 0,0013 1 E RTG2 GO:0016049 4,7,6,3 cell growth 4 0,0006 2 0,0025 1 E AVO2,AVO1 GO:0007534 9,6 gene conversion at mating-type locus 13 0,002 2 0,0025 1 E RAD1,RAD52 GO:0001320 9,8 age-dependent response to reactive oxygen species during chronological cell aging 2 0,0003 1 0,0013 1 E SOD1 GO:0019654 8 acetate fermentation 1 0,0002 1 0,0013 1 E ACS1 GO:0006417 8,7,6 regulation of protein biosynthesis 30 0,0046 4 0,005 1 E COX14,SLF1,ECM32,EAP1 GO:0016078 8 tRNA catabolism 4 0,0006 1 0,0013 1 E PAP2 GO:0006370 9 mRNA capping 3 0,0005 1 0,0013 1 E CET1 GO:0001306 7,6 age-dependent response to oxidative stress 7 0,0011 2 0,0025 1 E SOD1,CYR1 GO:0009749 8,7 response to glucose stimulus 5 0,0008 2 0,0025 1 E SNF3,RGT2 GO:0044247 8,7 cellular polysaccharide catabolism 12 0,0019 5 0,0063 1 E PCL6,GPH1,SGA1,PCL7,GDB1 GO:0046486 6,7 glycerolipid metabolism 4 0,0006 1 0,0013 1 E TGL4 GO:0045860 6 positive regulation of protein kinase activity 3 0,0005 2 0,0025 1 E PBS2,SSK2 GO:0000751 8,6 cell cycle arrest in response to pheromone 8 0,0012 4 0,005 1 E OPY2,GRR1,FAR10,FAR11 GO:0006878 8,9 copper ion homeostasis 7 0,0011 2 0,0025 1 E SOD1,SLF1 GO:0006312 8 mitotic recombination 26 0,004 6 0,0075 1 E RPD3,RAD59,RAD50,YRF1-2,RAD1,RAD52 GO:0006120 9,11,8 mitochondrial electron transport, NADH to ubiquinone 1 0,0002 1 0,0013 1 E NDI1 GO:0006664 7,8 glycolipid metabolism 3 0,0005 1 0,0013 1 E CSG2 GO:0008643 5,6 carbohydrate transport 34 0,0053 5 0,0063 1 E HXT6,HXT16,HXT5,HXT7,HXT13 GO:0000173 9,8 inactivation of MAPK activity during osmolarity sensing 5 0,0008 1 0,0013 1 E PTP2 GO:0006886 8,6,7 intracellular protein transport 239 0,037 41 0,0514 1 E PEX8,ATG4,PEX3,VPS73,PEX22,PEX25,ATG9,SDS22,CSE1,KAR2,SAM50,TOM6,ECM10,VAC8,IMP1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,TIM21,SSC1,YPT52,VPS30,ATG7,PEX19,ATG12,ATG19,VPS15,ENT3,PEX12,MTR10,ASM4,SSA1,MPT5,PEP1,VPS70,VPS21,BSD2,CRM1 GO:0006283 9,8 transcription-coupled nucleotide-excision repair 1 0,0002 1 0,0013 1 E RAD26 GO:0007039 7,8 vacuolar protein catabolism 10 0,0015 4 0,005 1 E PAI3,PRB1,VID30,LAP4 GO:0044255 5,6 cellular lipid metabolism 208 0,0322 38 0,0476 1 E YMR1,TAZ1,AYR1,FOX2,LAG1,SCT1,OSH6,MCR1,PBN1,LPP1,ERG9,CRD1,CSG2,MCT1,INO4,TGL4,ETR1,DAP1,IDP3,OAF1,TGL1,HST3,LSB6,TSC13,DPP1,GPT2,AGP2,YDC1,DPL1,YPK1,CHO1,YPC1,CKI1,MDH3,GPI19,SKN1,PDX3,SPO14 GO:0008610 6,5,7 lipid biosynthesis 124 0,0192 17 0,0213 1 E TAZ1,AYR1,LAG1,SCT1,OSH6,MCR1,PBN1,ERG9,CRD1,CSG2,INO4,ETR1,GPT2,CHO1,CKI1,GPI19,SKN1 GO:0030433 10,12,11,13 ER-associated protein catabolism 20 0,0031 4 0,005 1 E CNE1,NPL4,SEC12,QRI8 GO:0016053 6 organic acid biosynthesis 17 0,0026 3 0,0038 1 E ALD6,AYR1,ETR1 GO:0009414 6,5 response to water deprivation 10 0,0015 2 0,0025 1 E SIP18,STF2 GO:0001402 5,4 signal transduction during filamentous growth 6 0,0009 2 0,0025 1 E BMH2,BMH1 GO:0015672 7,8 monovalent inorganic cation transport 30 0,0046 9 0,0113 1 E ATP2,STF2,ATP5,ENA2,INH1,ATP15,ATP16,ATP3,ATP17 GO:0051180 5,6 vitamin transport 6 0,0009 1 0,0013 1 E AGP2 GO:0009071 8,9 serine family amino acid catabolism 5 0,0008 1 0,0013 1 E CHA1 GO:0000747 6,4 conjugation with cellular fusion 105 0,0163 18 0,0226 1 E POG1,CMP2,STE18,OPY2,GRR1,STE11,MDG1,PRM5,KAR2,RGA2,FAR10,PTP2,CNB1,AFR1,PRM8,STE5,MPT5,FAR11 GO:0019748 4 secondary metabolism 18 0,0028 3 0,0038 1 E COX15,HMX1,HEM15 GO:0051318 6 G1 phase 23 0,0036 3 0,0038 1 E TOR1,SWI5,GID8 GO:0045040 11,8,9,7,10 protein import into mitochondrial outer membrane 3 0,0005 1 0,0013 1 E SAM50 GO:0006437 10,11,9 tyrosyl-tRNA aminoacylation 2 0,0003 1 0,0013 1 E MSY1 GO:0018342 10,9 protein prenylation 5 0,0008 1 0,0013 1 E BET4 GO:0006901 6,7 vesicle coating 3 0,0005 1 0,0013 1 E SEC28 GO:0005993 9 trehalose catabolism 3 0,0005 2 0,0025 1 E NTH2,NTH1 GO:0051347 5 positive regulation of transferase activity 3 0,0005 2 0,0025 1 E PBS2,SSK2 GO:0006879 8,9 iron ion homeostasis 29 0,0045 5 0,0063 1 E HMX1,SSQ1,SMF3,ISU1,OCT1 GO:0006538 9,1 glutamate catabolism 2 0,0003 2 0,0025 1 E GAD1,UGA2 GO:0050801 4 ion homeostasis 102 0,0158 19 0,0238 1 E YVC1,CMP2,HMX1,SSQ1,SMF3,SKP1,SOD1,CSG2,PPZ2,ISU1,PTK2,COT1,COS3,RAV2,SLF1,OCT1,CNB1,IZH3,VHS3 GO:0051640 4 organelle localization 49 0,0076 12 0,015 1 E MLC1,ARC40,ARC35,MDM31,ARC15,ARP3,ARP2,TPM2,TPM1,MDM10,BUL1,ARC19 GO:0019954 3 asexual reproduction 77 0,0119 16 0,0201 1 E MLC1,SAC6,PPH22,LAS17,ERV14,SEC6,SEC10,RGA2,MUB1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1,REH1 GO:0007571 6,5 age-dependent general metabolic decline 8 0,0012 3 0,0038 1 E ATP2,SOD1,CYR1 GO:0007049 4 cell cycle 397 0,0615 51 0,0639 1 E BDF1,ZIP1,WHI5,AMA1,SAP155,BUB3,POG1,REC114,ADY2,PPH22,SIC1,PAP2,OPY2,SET3,SPO11,SKP1,PTK2,GRR1,GTS1,PCL5,MMS4,RAD50,MEC1,CCL1,MPS1,CDC37,CST9,MSC1,BCK2,VHS2,APC9,FAR10,TOR1,SIF2,RCK2,RAD52,SWI5,BMH2,WTM1,RIM4,CYR1,MAD1,GID8,BMH1,MUS81,MPT5,FAR11,SDS24,CLN3,VHS3,XRS2 GO:0009452 8 RNA capping 4 0,0006 1 0,0013 1 E CET1 GO:0046916 8 transition metal ion homeostasis 47 0,0073 9 0,0113 1 E HMX1,SSQ1,SMF3,SOD1,ISU1,COT1,SLF1,OCT1,IZH3 GO:0006662 5 glycerol ether metabolism 4 0,0006 1 0,0013 1 E TGL4 GO:0016571 12,9,10 histone methylation 17 0,0026 5 0,0063 1 E LEO1,CDC73,SET2,SWD2,PAF1 GO:0016568 9 chromatin modification 181 0,028 25 0,0313 1 E BDF1,RPD3,LEO1,YAF9,SET3,CDC46,ISW1,SWI1,PNC1,CDC73,TRA1,SET2,EPL1,HST3,RAD6,SWD2,SIF2,RSC9,PHO23,AHC1,PAF1,YKU80,MPT5,YKU70,SNF5 GO:0009259 7 ribonucleotide metabolism 41 0,0064 11 0,0138 1 E ATP2,STF2,ATP5,ADE16,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0000736 10,9 double-strand break repair via single-strand annealing, removal of nonhomologous ends 2 0,0003 1 0,0013 1 E RAD1 GO:0046128 8 purine ribonucleoside metabolism 8 0,0012 1 0,0013 1 E ISN1 GO:0016311 7 dephosphorylation 35 0,0054 7 0,0088 1 E GIP2,YMR1,PPH22,PPG1,PTP2,YPI1,LTP1 GO:0030835 12,7,8,9,10 negative regulation of actin filament depolymerization 2 0,0003 2 0,0025 1 E CAP2,CAP1 GO:0019363 8,7,9 pyridine nucleotide biosynthesis 8 0,0012 3 0,0038 1 E QNS1,BNA1,POS5 GO:0000902 5,4 cellular morphogenesis 144 0,0223 23 0,0288 1 E MLC1,SAC6,WHI5,LAS17,ERV14,GTS1,WHI4,SEC6,AVO2,SLG1,SEC10,RGA2,RNY1,RHO3,THP1,TPM2,EXO70,AFR1,AVO1,MYO3,TPM1,SEC15,PFY1 GO:0006476 8 protein amino acid deacetylation 13 0,002 3 0,0038 1 E RPD3,SET3,SIF2 GO:0000188 8 inactivation of MAPK activity 5 0,0008 1 0,0013 1 E PTP2 GO:0019243 8 methylglyoxal catabolism to D-lactate 3 0,0005 2 0,0025 1 E GLO4,GLO2 GO:0006010 10,11 glucose 6-phosphate utilization 2 0,0003 1 0,0013 1 E PGM2 GO:0007131 9,8 meiotic recombination 39 0,006 10 0,0125 1 E REC114,SPO11,MMS4,RAD50,MEC1,MSC1,RAD52,RIM4,MUS81,XRS2 GO:0006435 10,11,9 threonyl-tRNA aminoacylation 1 0,0002 1 0,0013 1 E MST1 GO:0051242 5 positive regulation of cellular physiological process 71 0,011 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0019395 7,8 fatty acid oxidation 11 0,0017 3 0,0038 1 E FOX2,IDP3,MDH3 GO:0005981 11,10,6 regulation of glycogen catabolism 4 0,0006 2 0,0025 1 E PCL6,PCL7 GO:0015940 8,9 pantothenate biosynthesis 8 0,0012 1 0,0013 1 E FMS1 GO:0031279 4 regulation of cyclase activity 1 0,0002 1 0,0013 1 E RAS2 GO:0006970 5 response to osmotic stress 59 0,0091 13 0,0163 1 E SAC6,SIP18,AIP1,LAS17,SLG1,SSK2,MYO3,AGP2,MET22,CIN5,PFY1,IQG1,GCY1 GO:0006625 10,7,8,9 protein targeting to peroxisome 15 0,0023 7 0,0088 1 E PEX8,PEX3,PEX22,PEX25,PEX5,PEX19,PEX12 GO:0006086 9,8 acetyl-CoA biosynthesis from pyruvate 2 0,0003 1 0,0013 1 E PDX1 GO:0019358 10,8,9 nicotinate nucleotide salvage 2 0,0003 1 0,0013 1 E PNC1 GO:0015985 7,9,8,10 energy coupled proton transport, down electrochemical gradient 20 0,0031 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0051016 13,8,9,10,11 barbed-end actin filament capping 2 0,0003 2 0,0025 1 E CAP2,CAP1 GO:0006560 8,9 proline metabolism 7 0,0011 2 0,0025 1 E PUT1,PUT3 GO:0051181 5,6 cofactor transport 4 0,0006 1 0,0013 1 E AGP2 GO:0006429 10,11,9 leucyl-tRNA aminoacylation 2 0,0003 1 0,0013 1 E NAM2 GO:0006089 7 lactate metabolism 5 0,0008 3 0,0038 1 E DLD3,GLO4,GLO2 GO:0006008 10,11 glucose 1-phosphate utilization 2 0,0003 1 0,0013 1 E PGM2 GO:0009206 9,1 purine ribonucleoside triphosphate biosynthesis 22 0,0034 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0006855 6,7,8 multidrug transport 8 0,0012 3 0,0038 1 E YRR1,GTS1,YRM1 GO:0006078 10,9,11,8 beta-1,6 glucan biosynthesis 4 0,0006 1 0,0013 1 E SKN1 GO:0006672 9,1 ceramide metabolism 7 0,0011 3 0,0038 1 E LAG1,YDC1,YPC1 GO:0000393 10,12 spliceosomal conformational changes to generate catalytic conformation 8 0,0012 1 0,0013 1 E PRP22 GO:0050791 3 regulation of physiological process 584 0,0905 86 0,1078 1 E ADR1,MAL13,PFK26,BUB3,POG1,RPD3,FYV10,COX14,YRR1,PPH22,SPT2,RMD5,SNF4,YAF9,SIC1,OPY2,PFK27,CDC46,SKP1,PCL6,GRR1,RPH1,VID30,NPR1,UGA3,PRX1,JSN1,GTS1,MEC1,CCL1,PNC1,INO4,MPS1,AHP1,AVO2,CDC37,UBC8,DHH1,RAV2,TRA1,SET2,BCK2,SLF1,GRX2,OAF1,CAP2,EPL1,APC9,HST3,FAR10,MRK1,TOR1,ECM32,SIF2,RSC9,MUB1,ARO80,DCS1,GRX1,PCL7,EAP1,CAP1,AVO1,SWI5,BMH2,HAP2,MAL33,TFS1,CIN5,PRP45,YKU80,CYR1,HAP5,YRM1,MAD1,GID8,BMH1,PBI2,MPT5,YKU70,AZF1,FAR11,PUT3,CLN3,CSR2,PHB1 GO:0006303 9,8 double-strand break repair via nonhomologous end-joining 19 0,0029 7 0,0088 1 E RPD3,FYV6,RAD50,DOA1,YKU80,YKU70,XRS2 GO:0000376 10 RNA splicing, via transesterification reactions with guanosine as nucleophile 7 0,0011 1 0,0013 1 E NAM2 GO:0006778 6 porphyrin metabolism 15 0,0023 3 0,0038 1 E COX15,HMX1,HEM15 GO:0006164 7,8 purine nucleotide biosynthesis 43 0,0067 11 0,0138 1 E ATP2,STF2,ATP5,ADE16,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0048309 7 endoplasmic reticulum inheritance 2 0,0003 1 0,0013 1 E MYO4 GO:0006612 10,8,9 protein targeting to membrane 31 0,0048 4 0,005 1 E KAR2,SSA4,SSA3,SSA1 GO:0006368 9 RNA elongation from RNA polymerase II promoter 22 0,0034 4 0,005 1 E LEO1,CDC73,THP1,PAF1 GO:0007006 6,7 mitochondrial membrane organization and biogenesis 19 0,0029 3 0,0038 1 E TAZ1,CRD1,SAM50 GO:0006190 8,1 inosine salvage 1 0,0002 1 0,0013 1 E ISN1 GO:0006374 10,12 nuclear mRNA splicing via U2-type spliceosome 9 0,0014 2 0,0025 1 E PRP5,PRP22 GO:0006103 9,6,7 2-oxoglutarate metabolism 2 0,0003 2 0,0025 1 E KGD1,KGD2 GO:0001315 8,7 age-dependent response to reactive oxygen species 2 0,0003 1 0,0013 1 E SOD1 GO:0008535 8 cytochrome c oxidase complex assembly 9 0,0014 2 0,0025 1 E COX15,COX20 GO:0051248 7,6 negative regulation of protein metabolism 9 0,0014 3 0,0038 1 E CAP2,CAP1,PHB1 GO:0042026 9 protein refolding 1 0,0002 1 0,0013 1 E ECM10 GO:0006620 11,9,7,10,8 posttranslational protein targeting to membrane 8 0,0012 1 0,0013 1 E KAR2 GO:0006896 10,9,8,7 Golgi to vacuole transport 18 0,0028 7 0,0088 1 E PEP12,GGA1,VTI1,VPS52,YPT7,VPS45,PEP7 GO:0030503 6,5 regulation of cell redox homeostasis 10 0,0015 4 0,005 1 E PRX1,AHP1,GRX2,GRX1 GO:0017038 6,7 protein import 91 0,0141 12 0,015 1 E PEX3,PEX25,SAM50,TOM6,HSP78,TIM21,SSC1,PEX19,PEX12,MTR10,ASM4,SSA1 GO:0006104 7,9 succinyl-CoA metabolism 2 0,0003 1 0,0013 1 E LSC1 GO:0016077 8 snoRNA catabolism 4 0,0006 1 0,0013 1 E PAP2 GO:0015986 9,11,8,10,7,12 ATP synthesis coupled proton transport 20 0,0031 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0007033 6 vacuole organization and biogenesis 39 0,006 11 0,0138 1 E MLC1,SEC17,VAM6,VAC8,VTI1,TPM2,TPM1,YPT7,PBI2,CLN3,VPS45 GO:0051339 4 regulation of lyase activity 1 0,0002 1 0,0013 1 E RAS2 GO:0006116 11,1 NADH oxidation 3 0,0005 2 0,0025 1 E GUT2,NDE1 GO:0009438 6 methylglyoxal metabolism 3 0,0005 2 0,0025 1 E GLO4,GLO2 GO:0051129 6 negative regulation of cell organization and biogenesis 5 0,0008 2 0,0025 1 E CAP2,CAP1 GO:0031577 7 spindle checkpoint 21 0,0033 4 0,005 1 E BUB3,PPH22,MPS1,MAD1 GO:0000183 13,8,11,6 chromatin silencing at rDNA 14 0,0022 2 0,0025 1 E RPD3,PNC1 GO:0006833 6,7 water transport 3 0,0005 1 0,0013 1 E AQY1 GO:0009142 7,8 nucleoside triphosphate biosynthesis 24 0,0037 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0051302 5 regulation of cell division 1 0,0002 1 0,0013 1 E MUB1 GO:0043414 7 biopolymer methylation 35 0,0054 7 0,0088 1 E LEO1,CDC73,SET2,PPM1,SWD2,PAF1,TRM12 GO:0006499 12,11 N-terminal protein myristoylation 5 0,0008 1 0,0013 1 E FAA1 GO:0016036 6,7 cellular response to phosphate starvation 3 0,0005 1 0,0013 1 E PHO2 GO:0009145 8,9 purine nucleoside triphosphate biosynthesis 22 0,0034 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0009141 7 nucleoside triphosphate metabolism 25 0,0039 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0030467 7,8,6 establishment and/or maintenance of cell polarity (sensu Fungi) 107 0,0166 16 0,0201 1 E MLC1,SAC6,LAS17,ERV14,SEC6,SLG1,SEC10,RGA2,RHO3,THP1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1 GO:0009199 8 ribonucleoside triphosphate metabolism 23 0,0036 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0045116 8 protein neddylation 5 0,0008 2 0,0025 1 E ULA1,UBA3 GO:0045011 11 actin cable formation 5 0,0008 2 0,0025 1 E TPM2,TPM1 GO:0051274 10,9,8 beta-glucan biosynthesis 8 0,0012 1 0,0013 1 E SKN1 GO:0045912 7,6 negative regulation of carbohydrate metabolism 9 0,0014 5 0,0063 1 E FYV10,RMD5,VID30,UBC8,GID8 GO:0018346 11,1 protein amino acid prenylation 5 0,0008 1 0,0013 1 E BET4 GO:0051301 4 cell division 123 0,0191 18 0,0226 1 E MLC1,SAC6,PPH22,LAS17,ERV14,SEC6,SEC10,RGA2,THP1,MUB1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1,IQG1,REH1 GO:0030832 9 regulation of actin filament length 3 0,0005 2 0,0025 1 E CAP2,CAP1 GO:0043255 8,7,6 regulation of carbohydrate biosynthesis 16 0,0025 7 0,0088 1 E FYV10,RMD5,PCL6,VID30,UBC8,PCL7,GID8 GO:0009150 8 purine ribonucleotide metabolism 40 0,0062 11 0,0138 1 E ATP2,STF2,ATP5,ADE16,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0007530 3 sex determination 23 0,0036 3 0,0038 1 E RAD1,RAD52,YKU80 GO:0016032 2 viral life cycle 2 0,0003 1 0,0013 1 E MAK32 GO:0051171 5 regulation of nitrogen metabolism 8 0,0012 2 0,0025 1 E VID30,NPR1 GO:0018345 10,9 protein palmitoylation 3 0,0005 1 0,0013 1 E SHR5 GO:0046174 7 polyol catabolism 3 0,0005 1 0,0013 1 E DAK2 GO:0042538 7 hyperosmotic salinity response 1 0,0002 1 0,0013 1 E MET22 GO:0001310 9,8 extrachromosomal rDNA circle accumulation during replicative cell aging 1 0,0002 1 0,0013 1 E RTG2 GO:0048522 4 positive regulation of cellular process 71 0,011 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0006873 5 cell ion homeostasis 98 0,0152 19 0,0238 1 E YVC1,CMP2,HMX1,SSQ1,SMF3,SKP1,SOD1,CSG2,PPZ2,ISU1,PTK2,COT1,COS3,RAV2,SLF1,OCT1,CNB1,IZH3,VHS3 GO:0015893 5,6,7 drug transport 13 0,002 3 0,0038 1 E YRR1,GTS1,YRM1 GO:0006687 8,9 glycosphingolipid metabolism 3 0,0005 1 0,0013 1 E CSG2 GO:0006415 9,8 translational termination 6 0,0009 1 0,0013 1 E ECM32 GO:0015718 7,8 monocarboxylic acid transport 8 0,0012 2 0,0025 1 E ADY2,JEN1 GO:0000348 9,11,13 nuclear mRNA branch site recognition 3 0,0005 1 0,0013 1 E PRP5 GO:0043038 7,8 amino acid activation 30 0,0046 6 0,0075 1 E MSY1,FMT1,NAM2,MSK1,MSR1,MST1 GO:0006656 10,9,11 phosphatidylcholine biosynthesis 7 0,0011 1 0,0013 1 E CKI1 GO:0042732 8,9 D-xylose metabolism 4 0,0006 3 0,0038 1 E YPR1,GRE3,GCY1 GO:0006003 9,1 fructose 2,6-bisphosphate metabolism 2 0,0003 2 0,0025 1 E PFK26,PFK27 GO:0009435 9,8,11,10 NAD biosynthesis 7 0,0011 2 0,0025 1 E QNS1,BNA1 GO:0006629 5 lipid metabolism 222 0,0344 41 0,0514 1 E YMR1,TAZ1,AYR1,FOX2,LAG1,SCT1,OSH6,MCR1,PBN1,LPP1,ERG9,CRD1,CSG2,EHT1,FAA1,MCT1,INO4,TGL4,ETR1,DAP1,IDP3,OAF1,TGL1,HST3,LSB6,TSC13,DPP1,GPT2,AGP2,IZH3,YDC1,DPL1,YPK1,CHO1,YPC1,CKI1,MDH3,GPI19,SKN1,PDX3,SPO14 GO:0006545 9,1 glycine biosynthesis 2 0,0003 1 0,0013 1 E AGX1 GO:0019795 8,9 nonprotein amino acid biosynthesis 6 0,0009 2 0,0025 1 E ALD3,ALD2 GO:0006616 13,11,9,12,10 SRP-dependent cotranslational protein targeting to membrane, translocation 9 0,0014 4 0,005 1 E KAR2,SSA4,SSA3,SSA1 GO:0040007 2 growth 113 0,0175 23 0,0288 1 E MLC1,SIP2,PPH22,VPS60,STE11,TPK1,RIM21,AVO2,RGA2,TPK2,CAP2,TPM2,NGR1,RIM20,BCY1,AVO1,BMH2,TPM1,STE5,BMH1,RAS2,DIA3,REH1 GO:0043407 7 negative regulation of MAPK activity 5 0,0008 1 0,0013 1 E PTP2 GO:0009889 5 regulation of biosynthesis 46 0,0071 11 0,0138 1 E FYV10,COX14,RMD5,PCL6,VID30,UBC8,SLF1,ECM32,PCL7,EAP1,GID8 GO:0016925 8 protein sumoylation 6 0,0009 2 0,0025 1 E SIZ1,AOS1 GO:0009086 9,10,8 methionine biosynthesis 5 0,0008 1 0,0013 1 E MET22 GO:0007105 6 cytokinesis, site selection 65 0,0101 10 0,0125 1 E SAC6,LAS17,ERV14,SEC6,SEC10,THP1,EXO70,MYO3,SEC15,PFY1 GO:0009201 8,9 ribonucleoside triphosphate biosynthesis 23 0,0036 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0042727 8 riboflavin and derivative biosynthesis 8 0,0012 3 0,0038 1 E RIB4,RIB5,FAD1 GO:0015937 8,9 coenzyme A biosynthesis 7 0,0011 1 0,0013 1 E VHS3 GO:0042044 5,6 fluid transport 3 0,0005 1 0,0013 1 E AQY1 GO:0030005 7 di-, tri-valent inorganic cation homeostasis 52 0,0081 10 0,0125 1 E HMX1,SSQ1,SMF3,SOD1,CSG2,ISU1,COT1,SLF1,OCT1,IZH3 GO:0019413 8 acetate biosynthesis 4 0,0006 1 0,0013 1 E ALD6 GO:0006567 9,1 threonine catabolism 3 0,0005 1 0,0013 1 E CHA1 GO:0046040 10 IMP metabolism 14 0,0022 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0006110 11,12,9,6 regulation of glycolysis 5 0,0008 2 0,0025 1 E PFK26,PFK27 GO:0015727 8,9 lactate transport 1 0,0002 1 0,0013 1 E JEN1 GO:0006784 9,8 heme a biosynthesis 4 0,0006 1 0,0013 1 E COX15 GO:0000290 10,11 deadenylylation-dependent decapping 7 0,0011 2 0,0025 1 E DHH1,DCS1 GO:0001321 7,6 age-dependent general metabolic decline during replicative cell aging 1 0,0002 1 0,0013 1 E ATP2 GO:0000038 7,8 very-long-chain fatty acid metabolism 2 0,0003 1 0,0013 1 E TSC13 GO:0007187 7,8 G-protein signaling, coupled to cyclic nucleotide second messenger 4 0,0006 2 0,0025 1 E CYR1,RAS2 GO:0042157 7 lipoprotein metabolism 36 0,0056 5 0,0063 1 E SHR5,PBN1,FAA1,BET4,GPI19 GO:0000080 7 G1 phase of mitotic cell cycle 23 0,0036 3 0,0038 1 E TOR1,SWI5,GID8 GO:0006779 7 porphyrin biosynthesis 14 0,0022 2 0,0025 1 E COX15,HEM15 GO:0048193 8,6,7 Golgi vesicle transport 141 0,0218 27 0,0338 1 E YPT1,SFT2,SNC1,BET3,ERV14,KRE11,SEC17,PEP12,BET5,SEC6,GGA1,SEC9,SEC10,GOS1,VTI1,ENT5,EXO70,VPS52,SEC12,SEC15,YPT7,ENT3,EMP46,VPS45,SSO1,SEC28,PEP7 GO:0042375 6 quinone cofactor metabolism 3 0,0005 2 0,0025 1 E COQ9,COQ3 GO:0006735 11,1 NADH regeneration 2 0,0003 1 0,0013 1 E MDH3 GO:0016236 5 macroautophagy 2 0,0003 1 0,0013 1 E ATG9 GO:0030003 6 cation homeostasis 89 0,0138 16 0,0201 1 E YVC1,HMX1,SSQ1,SMF3,SKP1,SOD1,CSG2,PPZ2,ISU1,COT1,COS3,RAV2,SLF1,OCT1,IZH3,VHS3 GO:0043086 4 negative regulation of enzyme activity 6 0,0009 1 0,0013 1 E PTP2 GO:0001301 6,5 progressive alteration of chromatin during cell aging 10 0,0015 3 0,0038 1 E RPD3,RTG2,MPT5 GO:0006904 7,8 vesicle docking during exocytosis 12 0,0019 5 0,0063 1 E SEC6,SEC10,EXO70,SEC15,PEP7 GO:0051338 4 regulation of transferase activity 21 0,0033 5 0,0063 1 E SIC1,PBS2,SSK2,PTP2,CLN3 GO:0046839 7,8 phospholipid dephosphorylation 7 0,0011 1 0,0013 1 E YMR1 GO:0030437 6 sporulation (sensu Fungi) 92 0,0143 21 0,0263 1 E BDF1,AMA1,SHP1,PUP2,UBC4,ERV14,GTS1,AQY1,RIM21,ADE16,SGA1,RIM11,UBI4,NEM1,EMI2,DIT1,BMH2,BMH1,RAS2,PRE1,SPO14 GO:0006525 8,9,6,5 arginine metabolism 15 0,0023 2 0,0025 1 E CAR2,ARG4 GO:0007094 10,8 mitotic spindle checkpoint 21 0,0033 4 0,005 1 E BUB3,PPH22,MPS1,MAD1 GO:0006869 5,6 lipid transport 20 0,0031 3 0,0038 1 E FAA1,PXA2,PXA1 GO:0043094 5 metabolic compound salvage 16 0,0025 2 0,0025 1 E PNC1,ISN1 GO:0006323 7 DNA packaging 205 0,0318 26 0,0326 1 E BDF1,RPD3,LEO1,YAF9,SET3,CDC46,ISW1,SWI1,PNC1,CDC73,TRA1,SET2,EPL1,HST3,RAD6,SWD2,SIF2,RSC9,PHO23,AHC1,PAF1,YKU80,MPT5,YKU70,SNF5,QRI8 GO:0046149 6 pigment catabolism 1 0,0002 1 0,0013 1 E HMX1 GO:0019236 6 response to pheromone 73 0,0113 16 0,0201 1 E POG1,CMP2,STE18,OPY2,GRR1,STE11,MDG1,RGA2,FAR10,PTP2,KIN82,CNB1,AFR1,STE5,MPT5,FAR11 GO:0046487 6,7 glyoxylate metabolism 4 0,0006 2 0,0025 1 E CIT2,MDH3 GO:0016074 7 snoRNA metabolism 13 0,002 2 0,0025 1 E PAP2,SWD2 GO:0009051 11,12,13,9 pentose-phosphate shunt, oxidative branch 3 0,0005 2 0,0025 1 E ZWF1,SOL4 GO:0042145 8,5 homotypic vacuole fusion, non-autophagic 11 0,0017 5 0,0063 1 E SEC17,VAM6,VAC8,YPT7,CLN3 GO:0006883 8 sodium ion homeostasis 3 0,0005 2 0,0025 1 E PPZ2,COS3 GO:0051243 5 negative regulation of cellular physiological process 170 0,0263 23 0,0288 1 E RPD3,FYV10,SPT2,RMD5,YAF9,OPY2,CDC46,GRR1,RPH1,VID30,CCL1,PNC1,UBC8,CAP2,HST3,FAR10,SIF2,CAP1,YKU80,GID8,YKU70,FAR11,PHB1 GO:0006513 10 protein monoubiquitination 22 0,0034 6 0,0075 1 E UBR1,UBC4,UBC8,UBI4,RAD6,BUL1 GO:0043254 8,7,6 regulation of protein complex assembly 3 0,0005 2 0,0025 1 E SKP1,RAV2 GO:0000067 5 DNA replication and chromosome cycle 3 0,0005 1 0,0013 1 E CST9 GO:0006893 10,8,7,9 Golgi to plasma membrane transport 20 0,0031 7 0,0088 1 E SNC1,SEC6,SEC9,SEC10,EXO70,SEC15,SSO1 GO:0006298 8,10,7 mismatch repair 20 0,0031 3 0,0038 1 E HYS2,EXO1,HSM3 GO:0000079 6 regulation of cyclin dependent protein kinase activity 14 0,0022 2 0,0025 1 E SIC1,CLN3 GO:0006289 8,7 nucleotide-excision repair 31 0,0048 5 0,0063 1 E RAD2,HYS2,RAD1,RAD26,RFA1 GO:0017004 8 cytochrome complex assembly 5 0,0008 1 0,0013 1 E QCR7 GO:0015879 6,7 carnitine transport 1 0,0002 1 0,0013 1 E AGP2 GO:0007008 7,8 outer mitochondrial membrane organization and biogenesis 4 0,0006 1 0,0013 1 E SAM50 GO:0045324 9,8,7 late endosome to vacuole transport 16 0,0025 3 0,0038 1 E VPS60,VPS38,VPS8 GO:0006641 8,7,9 triacylglycerol metabolism 4 0,0006 1 0,0013 1 E TGL4 GO:0006488 11,1 dolichol-linked oligosaccharide biosynthesis 10 0,0015 2 0,0025 1 E ALG2,ALG13 GO:0019933 8 cAMP-mediated signaling 8 0,0012 3 0,0038 1 E PDE1,CYR1,RAS2 GO:0006376 9,11,13 mRNA splice site selection 3 0,0005 1 0,0013 1 E LUC7 GO:0045815 4 positive regulation of gene expression, epigenetic 9 0,0014 2 0,0025 1 E RPD3,MPT5 GO:0006188 10,11 IMP biosynthesis 14 0,0022 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0007129 9 synapsis 9 0,0014 2 0,0025 1 E ZIP1,CST9 GO:0009893 5 positive regulation of metabolism 68 0,0105 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0006623 10,8,9 protein targeting to vacuole 59 0,0091 14 0,0175 1 E ATG4,VPS73,ATG9,VAC8,YPT52,VPS30,ATG7,ATG12,ATG19,VPS15,PEP1,VPS70,VPS21,BSD2 GO:0006551 8,9 leucine metabolism 7 0,0011 1 0,0013 1 E ARO10 GO:0000302 7,6 response to reactive oxygen species 7 0,0011 2 0,0025 1 E ZWF1,SOD1 GO:0009068 8,9 aspartate family amino acid catabolism 10 0,0015 3 0,0038 1 E ASP3-3,CHA1,ASP3-4 GO:0009437 7,8 carnitine metabolism 3 0,0005 1 0,0013 1 E CAT2 GO:0006642 9,8,10 triacylglycerol mobilization 2 0,0003 1 0,0013 1 E TGL4 GO:0016579 9 protein deubiquitination 18 0,0028 5 0,0063 1 E RUP1,UBP15,UBP6,UBI4,UBP2 GO:0000358 11,12,13,14 formation of catalytic U2-type spliceosome for second transesterification step 2 0,0003 1 0,0013 1 E PRP22 GO:0015846 6,7 polyamine transport 10 0,0015 2 0,0025 1 E PTK2,AGP2 GO:0006000 8,9 fructose metabolism 5 0,0008 3 0,0038 1 E PFK26,PFK27,HXK1 GO:0031326 6 regulation of cellular biosynthesis 46 0,0071 11 0,0138 1 E FYV10,COX14,RMD5,PCL6,VID30,UBC8,SLF1,ECM32,PCL7,EAP1,GID8 GO:0006808 6 regulation of nitrogen utilization 8 0,0012 2 0,0025 1 E VID30,NPR1 GO:0000370 10,11,12,13,14 U2-type nuclear mRNA branch site recognition 3 0,0005 1 0,0013 1 E PRP5 GO:0042180 5 ketone metabolism 4 0,0006 2 0,0025 1 E KGD1,KGD2 GO:0048523 4 negative regulation of cellular process 170 0,0263 23 0,0288 1 E RPD3,FYV10,SPT2,RMD5,YAF9,OPY2,CDC46,GRR1,RPH1,VID30,CCL1,PNC1,UBC8,CAP2,HST3,FAR10,SIF2,CAP1,YKU80,GID8,YKU70,FAR11,PHB1 GO:0045762 10,11,6 positive regulation of adenylate cyclase activity 1 0,0002 1 0,0013 1 E RAS2 GO:0006562 9,1 proline catabolism 4 0,0006 2 0,0025 1 E PUT1,PUT3 GO:0006490 12,11 oligosaccharide-lipid intermediate assembly 3 0,0005 1 0,0013 1 E ALG2 GO:0006098 10,11,12,8 pentose-phosphate shunt 9 0,0014 3 0,0038 1 E ZWF1,TKL2,SOL4 GO:0006996 5 organelle organization and biogenesis 1017 0,1576 132 0,1654 1 E BDF1,PEX8,VPS29,MLC1,SAC6,ADR1,ARC40,RPD3,TAZ1,PEX2,LEO1,ARC35,PPH22,MDM31,ARC15,HUA1,SFT2,SNF4,YAF9,RAD59,PAP2,SET3,CDC46,AIP1,SKP1,RPL5,LAS17,CRD1,VPS60,ERV14,DNM1,ARP3,SEC17,PEX3,ISW1,VPS5,EST3,SWI1,NUD1,VAM6,PEX22,PEX25,BBC1,RAD50,MEC1,SCD5,RPO41,SEC6,KAR2,PNC1,YME1,SAM50,CDC73,MPS1,YRF1-2,MYO4,CDC37,SLG1,PBS2,VPS17,HMI1,TRA1,VAC8,SEC10,VTI1,SET2,OAF1,RGA2,SSK2,CAP2,HSP78,EPL1,PEX5,RHO3,ENT5,APC9,HST3,LSB6,MSB3,THP1,RAD6,SWD2,TOR1,SIF2,ARP2,RSC9,PHO23,TPM2,VPS38,EXO70,RAD52,SPC105,NGR1,PRP12,PEX29,VPS52,NEM1,SCP1,PEX19,CAP1,ENT1,MYO3,PEP8,FIS1,POP5,TPM1,MDM34,AHC1,SEC15,PAF1,YPT7,ENT3,MDM10,PEX12,YKU80,PFY1,IQG1,BUL1,ASM4,PBI2,MPT5,YKU70,SNF5,ARC19,CLN3,MMM1,VPS45,CRM1,VPS8,QRI8,LSB5,XRS2 GO:0009225 6 nucleotide-sugar metabolism 5 0,0008 1 0,0013 1 E UGP1 GO:0006650 8,9 glycerophospholipid metabolism 46 0,0071 6 0,0075 1 E AYR1,PBN1,LSB6,CHO1,CKI1,GPI19 GO:0001304 7,6 progressive alteration of chromatin during replicative cell aging 9 0,0014 3 0,0038 1 E RPD3,RTG2,MPT5 GO:0006767 6 water-soluble vitamin metabolism 74 0,0115 18 0,0226 1 E ZWF1,RIB4,CAT2,TKL2,QNS1,RIB5,SOL4,PNC1,FAD1,BNA1,IDP3,BIO3,POS5,THI21,THI3,GUT2,MDH3,NDE1 GO:0042138 10,8,9 meiotic DNA double-strand break formation 9 0,0014 4 0,005 1 E REC114,SPO11,RAD50,XRS2 GO:0031325 6 positive regulation of cellular metabolism 68 0,0105 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0000023 8 maltose metabolism 5 0,0008 1 0,0013 1 E MAL12 GO:0018410 8 peptide or protein carboxyl-terminal blocking 1 0,0002 1 0,0013 1 E PPM1 GO:0001324 8,7 age-dependent response to oxidative stress during chronological cell aging 7 0,0011 2 0,0025 1 E SOD1,CYR1 GO:0007186 6 G-protein coupled receptor protein signaling pathway 27 0,0042 9 0,0113 1 E STE18,STE11,MDG1,RGA2,PTP2,AFR1,STE5,CYR1,RAS2 GO:0018987 4 osmoregulation 2 0,0003 1 0,0013 1 E VPS45 GO:0000025 9 maltose catabolism 5 0,0008 1 0,0013 1 E MAL12 GO:0007242 5 intracellular signaling cascade 107 0,0166 23 0,0288 1 E YMR1,SHR5,PKH2,TPK1,RTG2,TAX4,SLG1,PBS2,RGA2,TPK2,SSK2,PDE1,RHO3,LSB6,PTP2,BMH2,IRA2,RSF1,CYR1,DPL1,BMH1,RAS2,BAG7 GO:0006801 6 superoxide metabolism 1 0,0002 1 0,0013 1 E SOD1 GO:0046459 7,8 short-chain fatty acid metabolism 2 0,0003 1 0,0013 1 E HST3 GO:0000749 7,5 response to pheromone during conjugation with cellular fusion 53 0,0082 11 0,0138 1 E STE18,OPY2,GRR1,STE11,MDG1,RGA2,FAR10,PTP2,AFR1,STE5,FAR11 GO:0043144 8 snoRNA processing 4 0,0006 1 0,0013 1 E SWD2 GO:0046497 9,8 nicotinate nucleotide metabolism 2 0,0003 1 0,0013 1 E PNC1 GO:0006067 6 ethanol metabolism 10 0,0015 4 0,005 1 E SYM1,ADH2,ALD4,NDE1 GO:0009113 8,7 purine base biosynthesis 6 0,0009 2 0,0025 1 E PHO2,ADE8 GO:0030474 8,5 spindle pole body duplication 13 0,002 2 0,0025 1 E MPS1,CDC37 GO:0006846 8,9 acetate transport 1 0,0002 1 0,0013 1 E ADY2 GO:0042168 7,6 heme metabolism 15 0,0023 3 0,0038 1 E COX15,HMX1,HEM15 GO:0007001 7 chromosome organization and biogenesis (sensu Eukaryota) 243 0,0377 33 0,0414 1 E BDF1,RPD3,LEO1,YAF9,RAD59,SET3,CDC46,ISW1,EST3,SWI1,RAD50,MEC1,PNC1,CDC73,YRF1-2,TRA1,SET2,EPL1,HST3,RAD6,SWD2,SIF2,RSC9,PHO23,RAD52,AHC1,PAF1,YKU80,MPT5,YKU70,SNF5,QRI8,XRS2 GO:0006576 6,7 biogenic amine metabolism 25 0,0039 5 0,0063 1 E ALD3,CAT2,FMS1,ALD2,TRP4 GO:0030834 11,7,8,9 regulation of actin filament depolymerization 2 0,0003 2 0,0025 1 E CAP2,CAP1 GO:0006325 8 establishment and/or maintenance of chromatin architecture 205 0,0318 26 0,0326 1 E BDF1,RPD3,LEO1,YAF9,SET3,CDC46,ISW1,SWI1,PNC1,CDC73,TRA1,SET2,EPL1,HST3,RAD6,SWD2,SIF2,RSC9,PHO23,AHC1,PAF1,YKU80,MPT5,YKU70,SNF5,QRI8 GO:0045941 8 positive regulation of transcription 65 0,0101 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0006097 7,8 glyoxylate cycle 4 0,0006 2 0,0025 1 E CIT2,MDH3 GO:0006445 9,8,7 regulation of translation 29 0,0045 4 0,005 1 E COX14,SLF1,ECM32,EAP1 GO:0000724 9,8 double-strand break repair via homologous recombination 18 0,0028 6 0,0075 1 E RAD59,RAD50,RAD52,YKU80,YKU70,XRS2 GO:0000288 9,1 mRNA catabolism, deadenylylation-dependent decay 20 0,0031 4 0,005 1 E JSN1,DHH1,DCS1,MPT5 GO:0006479 9,8 protein amino acid methylation 20 0,0031 6 0,0075 1 E LEO1,CDC73,SET2,PPM1,SWD2,PAF1 GO:0006418 9,10,8 tRNA aminoacylation for protein translation 30 0,0046 6 0,0075 1 E MSY1,FMT1,NAM2,MSK1,MSR1,MST1 GO:0009605 4 response to external stimulus 27 0,0042 7 0,0088 1 E SIP2,PHO2,PRB1,SIP5,ASP3-3,ASP3-4,DPL1 GO:0018348 12,11 protein amino acid geranylgeranylation 4 0,0006 1 0,0013 1 E BET4 GO:0006308 6,7 DNA catabolism 11 0,0017 4 0,005 1 E REC114,SPO11,RAD50,XRS2 GO:0007126 7 meiosis 129 0,02 22 0,0276 1 E BDF1,ZIP1,AMA1,REC114,ADY2,SET3,SPO11,MMS4,RAD50,MEC1,CST9,MSC1,TOR1,SIF2,RCK2,RAD52,WTM1,RIM4,CYR1,MUS81,SDS24,XRS2 GO:0031163 6 metallo-sulfur cluster assembly 9 0,0014 2 0,0025 1 E ISU1,QCR9 GO:0006269 11 DNA replication, synthesis of RNA primer 7 0,0011 2 0,0025 1 E PRI1,RFA1 GO:0000282 7,9,10,8 bud site selection 65 0,0101 10 0,0125 1 E SAC6,LAS17,ERV14,SEC6,SEC10,THP1,EXO70,MYO3,SEC15,PFY1 GO:0019935 7 cyclic-nucleotide-mediated signaling 8 0,0012 3 0,0038 1 E PDE1,CYR1,RAS2 GO:0006914 4 autophagy 36 0,0056 11 0,0138 1 E ATG4,NVJ1,ATG1,ATG9,ATG17,VAC8,GTR2,SNX4,VPS30,ATG7,ATG12 GO:0040008 3 regulation of growth 4 0,0006 3 0,0038 1 E AVO2,NGR1,AVO1 GO:0019674 10,9 NAD metabolism 14 0,0022 4 0,005 1 E QNS1,BNA1,GUT2,NDE1 GO:0006614 12,10,8,11,9 SRP-dependent cotranslational protein targeting to membrane 19 0,0029 4 0,005 1 E KAR2,SSA4,SSA3,SSA1 GO:0007189 9,1 G-protein signaling, adenylate cyclase activating pathway 2 0,0003 1 0,0013 1 E RAS2 GO:0044238 4 primary metabolism 3152 0,4884 416 0,5213 1 E SSA2,BDF1,GIP2,SCL1,CBS2,TFG1,PGM2,MEF2,ADR1,SIP2,MAL13,PFK26,SRL3,AMA1,SDH2,USA1,ULA1,TDH3,PRE7,UBR1,POG1,RPN11,ARO9,YMR1,REC114,RPN7,RPD3,ZWF1,ALD3,RPT1,FYV6,LSC1,SHR5,CNE1,PRP5,TAZ1,YPR1,MED4,DOG2,ECM2,COX15,SHP1,MDJ1,HSP82,FYV10,ADY2,LEO1,PUT1,GLC3,PUP2,AYR1,COX14,YRR1,MRPL1,SIZ1,PPH22,PTH1,RPB7,YPT1,PRE10,PHO2,TAD3,SPT2,RPT2,RMD5,MSY1,ATP2,FOX2,STF2,SNF4,YAF9,ATP5,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,SSQ1,LAG1,RAD59,SCT1,PAP2,ATP10,PAI3,OSH6,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SET3,UBX7,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,SKP1,RPL5,ERG9,RAD2,RUP1,CRD1,NTA1,HYS2,MAL12,CSG2,EHT1,PCL6,ASK10,KNS1,NPL4,ALG2,UBP15,GLC8,SSE1,FAA1,GND2,CBP4,UFD1,MCT1,GRR1,BET4,STE11,RPH1,PRB1,GSF2,SNU71,AHA1,XYL2,SOL4,VID30,RPN9,UBP6,ISW1,CST6,AOS1,GLG2,MRPL28,UGA3,TPK1,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,STI1,DLD1,PRI1,GTS1,CIT2,PPG1,PMT2,SWS2,HXK1,MMS4,SSE2,UFD2,ADE16,FMS1,MAG1,SDH1,RAD50,KRE9,MEC1,CIT3,GLG1,MRP20,GDH3,CCL1,GPH1,DAP2,RPO41,MSF1,PNC1,ASP3-3,SAM50,MPD1,IST1,INO4,CDC73,ECM10,SGA1,BNA1,MSL5,PAN3,YRF1-2,FMT1,TGL4,ETR1,IMP2prime,RIM11,UBC8,NAM2,HSP104,MSC1,DHH1,RAV2,PBS2,TRA1,XKS1,IMP1,DAP1,SET2,ENO1,PSK2,MCM3,SRY1,CPR6,PPM1,CUS2,IDP3,SLF1,DOA1,ILS1,OAF1,TPK2,GPM1,SSK2,CAP2,HSP78,EPL1,HCH1,PHR1,SSA4,TGL1,APC9,CHA1,RAD1,HST3,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,THP1,TPS1,PTP2,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,ECM32,GRE3,SIF2,TSL1,RCK2,GAL10,RSC9,IPK1,SSC1,MSK1,PHO23,ARO80,DCS1,PRP4,RSE1,EXO1,RAD52,INH1,CAR2,KIN82,PUP1,COX20,PRP12,RAD26,PCL7,RIM20,ALD2,ATP15,APA1,UBA3,PET123,EAP1,ENO2,PEX19,CAP1,YAP1,PAP1,GLO4,AGX1,MRP8,RPN6,RTG1,SWI5,HSC82,BMH2,TSC13,POP5,VPS15,TRP4,MRPL16,SEC12,DPP1,ASP3-4,MSR1,HSP26,HAP2,CIT1,ADE8,AHC1,RSM18,MAL33,PAF1,TFS1,GPT2,AGP2,MUM2,MDM10,NTH1,YMR31,IZH3,YDC1,YPI1,TPS3,GUT2,TRM12,ATP16,MET22,ECM14,CIN5,UBP2,PRP45,RSF1,RIM4,YKU80,HAP5,YRM1,BUL1,GSY2,GID8,UBX6,GLK1,MRP51,DPL1,KTR4,GCY1,BMH1,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,PRP22,YPK1,SDH3,CHO1,SSA1,NUT2,PRE1,GAD1,MPT5,YKU70,AZF1,MRPL31,YTA7,ARO10,SNF5,PUT3,HYP2,YPK2,ARA1,HSM3,SDS24,YPC1,UBX5,CKI1,LAP4,RFA1,GLO2,LTP1,INO1,VPS45,ATP3,RSM28,ADE2,ATP17,MDH3,TDH1,UGA2,CSR2,QRI8,GPI19,PHB1,SKN1,PDX3,GDB1,TDP1,STE24,SPO14,ARG4,RPN14,GAL11,QCR7,APA2,SDH4,NDE1,XRS2 GO:0000082 7 G1/S transition of mitotic cell cycle 46 0,0071 12 0,015 1 E WHI5,SAP155,POG1,PPH22,SIC1,SKP1,PTK2,GRR1,BCK2,VHS2,CLN3,VHS3 GO:0000707 10,9,11,12,8 meiotic DNA recombinase assembly 5 0,0008 1 0,0013 1 E RAD52 GO:0019794 7,8 nonprotein amino acid metabolism 9 0,0014 2 0,0025 1 E ALD3,ALD2 GO:0006613 11,9,7,10,8 cotranslational protein targeting to membrane 22 0,0034 4 0,005 1 E KAR2,SSA4,SSA3,SSA1 GO:0000002 7 mitochondrial genome maintenance 27 0,0042 6 0,0075 1 E RPO41,HMI1,HSP78,PRP12,MDM10,MMM1 GO:0006096 10,11,8 glycolysis 21 0,0033 8 0,01 1 E PFK26,TDH3,TDH2,PFK27,ENO1,GPM1,ENO2,TDH1 GO:0006740 11,1 NADPH regeneration 12 0,0019 4 0,005 1 E ZWF1,TKL2,SOL4,IDP3 GO:0006995 6,7 cellular response to nitrogen starvation 5 0,0008 2 0,0025 1 E ASP3-3,ASP3-4 GO:0007119 7,5,6 budding cell isotropic bud growth 10 0,0015 4 0,005 1 E MLC1,RGA2,TPM2,TPM1 GO:0030258 6,7 lipid modification 12 0,0019 2 0,0025 1 E YMR1,LSB6 GO:0005997 8,9 xylulose metabolism 1 0,0002 1 0,0013 1 E XKS1 GO:0042542 8,7 response to hydrogen peroxide 3 0,0005 1 0,0013 1 E ZWF1 GO:0006528 8,9 asparagine metabolism 9 0,0014 2 0,0025 1 E ASP3-3,ASP3-4 GO:0045721 11,12,10,9,7,8 negative regulation of gluconeogenesis 9 0,0014 5 0,0063 1 E FYV10,RMD5,VID30,UBC8,GID8 GO:0046473 9,7,10 phosphatidic acid metabolism 1 0,0002 1 0,0013 1 E AYR1 GO:0007103 9,6 spindle pole body duplication in nuclear envelope 12 0,0019 2 0,0025 1 E MPS1,CDC37 GO:0006626 10,8,9 protein targeting to mitochondrion 47 0,0073 8 0,01 1 E SAM50,TOM6,ECM10,IMP1,HSP78,OCT1,TIM21,SSC1 GO:0009894 5 regulation of catabolism 12 0,0019 5 0,0063 1 E PFK26,PFK27,PCL6,MRK1,PCL7 GO:0019362 8,7 pyridine nucleotide metabolism 34 0,0053 11 0,0138 1 E ZWF1,TKL2,QNS1,SOL4,PNC1,BNA1,IDP3,POS5,GUT2,MDH3,NDE1 GO:0000350 11,13 formation of catalytic spliceosome for second transesterification step 4 0,0006 1 0,0013 1 E PRP22 GO:0043248 8 proteasome assembly 5 0,0008 2 0,0025 1 E HSP82,HSC82 GO:0006621 6 protein retention in ER 7 0,0011 1 0,0013 1 E ERD2 GO:0006461 7 protein complex assembly 148 0,0229 19 0,0238 1 E PRP5,COX15,HSP82,YPT1,LUC7,ATP10,SKP1,RPL5,CBP4,SAM50,RAV2,FMC1,RSE1,RAD52,COX20,HSC82,MDM10,VPS45,QCR7 GO:0006974 5 response to DNA damage stimulus 177 0,0274 32 0,0401 1 E BDF1,RPD3,FYV6,YIM1,RAD59,DDR48,RAD2,HYS2,RPH1,RAD18,MMS4,MAG1,RAD50,MEC1,PAN3,IMP2prime,DOA1,PHR1,RAD1,RAD6,EXO1,RAD52,RAD26,BMH2,YKU80,BMH1,MUS81,YKU70,HSM3,RFA1,TDP1,XRS2 GO:0051325 5 interphase 86 0,0133 15 0,0188 1 E WHI5,SAP155,POG1,PPH22,SIC1,SKP1,PTK2,GRR1,BCK2,VHS2,TOR1,SWI5,GID8,CLN3,VHS3 GO:0045002 9,8 double-strand break repair via single-strand annealing 11 0,0017 4 0,005 1 E RAD59,RAD50,RAD1,RAD52 GO:0001300 6,5 chronological cell aging 10 0,0015 4 0,005 1 E SOD1,GTS1,SCP1,CYR1 GO:0043488 9,8 regulation of mRNA stability 22 0,0034 4 0,005 1 E JSN1,DHH1,DCS1,MPT5 GO:0042149 6,7 cellular response to glucose starvation 2 0,0003 2 0,0025 1 E SIP2,SIP5 GO:0001558 5,8,7,4 regulation of cell growth 2 0,0003 2 0,0025 1 E AVO2,AVO1 GO:0019222 4 regulation of metabolism 429 0,0665 61 0,0764 1 E ADR1,MAL13,PFK26,POG1,RPD3,FYV10,COX14,YRR1,SPT2,RMD5,SNF4,YAF9,PFK27,CDC46,SKP1,PCL6,RPH1,VID30,NPR1,UGA3,JSN1,GTS1,CCL1,PNC1,INO4,UBC8,DHH1,RAV2,TRA1,SET2,SLF1,OAF1,CAP2,EPL1,HST3,MRK1,ECM32,SIF2,RSC9,ARO80,DCS1,PCL7,EAP1,CAP1,SWI5,HAP2,MAL33,TFS1,CIN5,PRP45,YKU80,HAP5,YRM1,GID8,PBI2,MPT5,YKU70,AZF1,PUT3,CSR2,PHB1 GO:0006814 8,9 sodium ion transport 3 0,0005 1 0,0013 1 E ENA2 GO:0009074 8,7,9 aromatic amino acid family catabolism 2 0,0003 2 0,0025 1 E ARO80,ARO10 GO:0015749 6,7 monosaccharide transport 21 0,0033 5 0,0063 1 E HXT6,HXT16,HXT5,HXT7,HXT13 GO:0007580 7,6 extrachromosomal circular DNA accumulation during cell aging 2 0,0003 1 0,0013 1 E RTG2 GO:0007116 6,4,5 regulation of cell budding 1 0,0002 1 0,0013 1 E MUB1 GO:0006665 7,8 sphingolipid metabolism 29 0,0045 7 0,0088 1 E LAG1,CSG2,YDC1,DPL1,YPK1,YPC1,SKN1 GO:0045426 8,7 quinone cofactor biosynthesis 3 0,0005 2 0,0025 1 E COQ9,COQ3 GO:0000910 5 cytokinesis 97 0,015 12 0,015 1 E MLC1,SAC6,LAS17,ERV14,SEC6,SEC10,THP1,EXO70,MYO3,SEC15,PFY1,IQG1 GO:0006311 9,8 meiotic gene conversion 15 0,0023 5 0,0063 1 E REC114,SPO11,RAD50,RAD52,XRS2 GO:0007117 6,4,5 budding cell bud growth 30 0,0046 6 0,0075 1 E MLC1,PPH22,RGA2,TPM2,TPM1,REH1 GO:0006468 8 protein amino acid phosphorylation 91 0,0141 18 0,0226 1 E SIP2,SLT2,PKH2,KNS1,STE11,TPK1,RIM11,PBS2,PSK2,TPK2,SSK2,MRK1,CMK1,RCK2,KIN82,VPS15,YPK1,YPK2 GO:0000738 7,8 DNA catabolism, exonucleolytic 3 0,0005 1 0,0013 1 E RAD50 GO:0007130 10 synaptonemal complex formation 5 0,0008 1 0,0013 1 E CST9 GO:0042364 7 water-soluble vitamin biosynthesis 38 0,0059 8 0,01 1 E RIB4,QNS1,RIB5,BNA1,BIO3,POS5,THI21,THI3 GO:0019483 9,1 beta-alanine biosynthesis 2 0,0003 2 0,0025 1 E ALD3,ALD2 GO:0006566 8,9 threonine metabolism 8 0,0012 1 0,0013 1 E CHA1 GO:0006559 9,8,10 L-phenylalanine catabolism 1 0,0002 1 0,0013 1 E ARO10 GO:0006403 4 RNA localization 83 0,0129 12 0,015 1 E NPL3,SHE2,MEX67,MYO4,THP1,TPM2,PAP1,TPM1,MTR10,ASM4,RPB4,CRM1 GO:0006345 11,10,5 loss of chromatin silencing 9 0,0014 2 0,0025 1 E RPD3,MPT5 GO:0006108 9,7 malate metabolism 3 0,0005 2 0,0025 1 E MDH1,MDH3 GO:0046351 8,7 disaccharide biosynthesis 4 0,0006 3 0,0038 1 E TPS1,TSL1,TPS3 GO:0006753 8 nucleoside phosphate metabolism 20 0,0031 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0006605 9,7,8 protein targeting 221 0,0342 41 0,0514 1 E PEX8,ATG4,PEX3,VPS73,PEX22,PEX25,ATG9,SDS22,CSE1,KAR2,SAM50,TOM6,ECM10,VAC8,IMP1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,TIM21,SSC1,YPT52,VPS30,ATG7,PEX19,ATG12,ATG19,VPS15,ENT3,PEX12,MTR10,ASM4,SSA1,MPT5,PEP1,VPS70,VPS21,BSD2,CRM1 GO:0009127 8,9 purine nucleoside monophosphate biosynthesis 16 0,0025 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0007234 7,6 osmosensory signaling pathway via two-component system 12 0,0019 3 0,0038 1 E PBS2,SSK2,PTP2 GO:0016569 10 covalent chromatin modification 59 0,0091 11 0,0138 1 E LEO1,SET3,CDC73,TRA1,SET2,EPL1,RAD6,SWD2,SIF2,AHC1,PAF1 GO:0006631 6,7 fatty acid metabolism 43 0,0067 10 0,0125 1 E FOX2,MCT1,ETR1,IDP3,OAF1,HST3,TSC13,AGP2,MDH3,PDX3 GO:0051595 7 response to methylglyoxal 3 0,0005 2 0,0025 1 E GLO4,GLO2 GO:0006575 6 amino acid derivative metabolism 27 0,0042 6 0,0075 1 E ALD3,CAT2,FMS1,SRY1,ALD2,TRP4 GO:0051382 8 kinetochore assembly 3 0,0005 1 0,0013 1 E SKP1 GO:0007163 6,7,5 establishment and/or maintenance of cell polarity 107 0,0166 16 0,0201 1 E MLC1,SAC6,LAS17,ERV14,SEC6,SLG1,SEC10,RGA2,RHO3,THP1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1 GO:0019751 6 polyol metabolism 8 0,0012 3 0,0038 1 E GUT1,TCO89,DAK2 GO:0009102 7,8 biotin biosynthesis 4 0,0006 1 0,0013 1 E BIO3 GO:0045184 5 establishment of protein localization 255 0,0395 46 0,0576 1 E PEX8,ATG4,SNX41,UFD1,PEX3,VPS73,PEX22,PEX25,ATG9,SCD5,SDS22,CSE1,KAR2,SAM50,TOM6,ECM10,NCE102,VAC8,IMP1,HSP78,PEX5,SSA4,ENT5,SSA3,OCT1,TIM21,SSC1,YPT52,VPS30,ATG7,PEX19,ATG12,ATG19,VPS15,ENT3,PEX12,MTR10,SSP120,ASM4,SSA1,MPT5,PEP1,VPS70,VPS21,BSD2,CRM1 GO:0048590 3 non-developmental growth 30 0,0046 6 0,0075 1 E MLC1,PPH22,RGA2,TPM2,TPM1,REH1 GO:0043118 4 negative regulation of physiological process 172 0,0267 23 0,0288 1 E RPD3,FYV10,SPT2,RMD5,YAF9,OPY2,CDC46,GRR1,RPH1,VID30,CCL1,PNC1,UBC8,CAP2,HST3,FAR10,SIF2,CAP1,YKU80,GID8,YKU70,FAR11,PHB1 GO:0006279 8 premeiotic DNA synthesis 4 0,0006 2 0,0025 1 E MUM2,RIM4 GO:0006787 7 porphyrin catabolism 1 0,0002 1 0,0013 1 E HMX1 GO:0019953 3 sexual reproduction 105 0,0163 18 0,0226 1 E POG1,CMP2,STE18,OPY2,GRR1,STE11,MDG1,PRM5,KAR2,RGA2,FAR10,PTP2,CNB1,AFR1,PRM8,STE5,MPT5,FAR11 GO:0000168 9,8 activation of MAPKK activity during osmolarity sensing 2 0,0003 1 0,0013 1 E SSK2 GO:0048015 7 phosphoinositide-mediated signaling 13 0,002 3 0,0038 1 E YMR1,TAX4,LSB6 GO:0043085 4 positive regulation of enzyme activity 7 0,0011 3 0,0038 1 E PBS2,SSK2,RAS2 GO:0006449 10,9,8 regulation of translational termination 3 0,0005 1 0,0013 1 E ECM32 GO:0007190 10,11,12,7 adenylate cyclase activation 1 0,0002 1 0,0013 1 E RAS2 GO:0019568 9,1 arabinose catabolism 4 0,0006 3 0,0038 1 E YPR1,GRE3,GCY1 GO:0000729 8,9,11,10 DNA double-strand break processing 3 0,0005 1 0,0013 1 E RAD50 GO:0046856 8,9 phosphoinositide dephosphorylation 7 0,0011 1 0,0013 1 E YMR1 GO:0051383 7 kinetochore organization and biogenesis 3 0,0005 1 0,0013 1 E SKP1 GO:0006354 8 RNA elongation 23 0,0036 5 0,0063 1 E LEO1,CDC73,SET2,THP1,PAF1 GO:0016574 12,9,10 histone ubiquitination 3 0,0005 1 0,0013 1 E RAD6 GO:0008654 8,7,9 phospholipid biosynthesis 52 0,0081 9 0,0113 1 E TAZ1,AYR1,SCT1,PBN1,INO4,GPT2,CHO1,CKI1,GPI19 GO:0006895 9,10,8,7 Golgi to endosome transport 10 0,0015 3 0,0038 1 E SFT2,ENT5,ENT3 GO:0006747 8,9 FAD biosynthesis 1 0,0002 1 0,0013 1 E FAD1 GO:0000060 11,9,8,10 protein import into nucleus, translocation 1 0,0002 1 0,0013 1 E SSA1 GO:0045229 5 external encapsulating structure organization and biogenesis 141 0,0218 23 0,0288 1 E ECM2,ECM21,ECM18,SLT2,PKH2,MTL1,ECM4,LRE1,KRE9,FMP45,TUS1,TAX4,SLG1,CNB1,SBE22,MYO3,ECM30,ECM14,ROT1,MPT5,SSD1,CSR2,SKN1 GO:0008298 5 intracellular mRNA localization 10 0,0015 4 0,005 1 E SHE2,MYO4,TPM2,TPM1 GO:0009168 9,1 purine ribonucleoside monophosphate biosynthesis 15 0,0023 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0016575 12,9 histone deacetylation 10 0,0015 2 0,0025 1 E SET3,SIF2 GO:0000722 9 telomerase-independent telomere maintenance 14 0,0022 4 0,005 1 E RAD59,RAD50,YRF1-2,RAD52 GO:0015804 7,8,9 neutral amino acid transport 5 0,0008 1 0,0013 1 E AVT3 GO:0046713 5,6 boron transport 1 0,0002 1 0,0013 1 E BOR1 GO:0051017 10 actin filament bundle formation 5 0,0008 2 0,0025 1 E TPM2,TPM1 GO:0043284 7,5,6 biopolymer biosynthesis 28 0,0043 8 0,01 1 E GLC3,PCL6,GLC8,GLG2,GLG1,PCL7,GSY2,SKN1 GO:0006972 6 hyperosmotic response 7 0,0011 1 0,0013 1 E MET22 GO:0019722 7 calcium-mediated signaling 7 0,0011 2 0,0025 1 E RSF1,DPL1 GO:0000209 10 protein polyubiquitination 19 0,0029 5 0,0063 1 E UBR1,UBC4,UBC8,UBI4,BUL1 GO:0045859 5 regulation of protein kinase activity 21 0,0033 5 0,0063 1 E SIC1,PBS2,SSK2,PTP2,CLN3 GO:0006558 8,7,9 L-phenylalanine metabolism 2 0,0003 1 0,0013 1 E ARO10 GO:0046394 7 carboxylic acid biosynthesis 17 0,0026 3 0,0038 1 E ALD6,AYR1,ETR1 GO:0006469 6 negative regulation of protein kinase activity 6 0,0009 1 0,0013 1 E PTP2 GO:0007243 6 protein kinase cascade 20 0,0031 4 0,005 1 E PKH2,PBS2,SSK2,PTP2 GO:0046185 6 aldehyde catabolism 5 0,0008 2 0,0025 1 E GLO4,GLO2 GO:0006746 8 FADH2 metabolism 2 0,0003 1 0,0013 1 E FAD1 GO:0016237 5 microautophagy 6 0,0009 3 0,0038 1 E NVJ1,VAC8,GTR2 GO:0051273 8,9 beta-glucan metabolism 9 0,0014 2 0,0025 1 E KRE9,SKN1 GO:0046513 10,9,11 ceramide biosynthesis 3 0,0005 1 0,0013 1 E LAG1 GO:0042592 3 homeostasis 114 0,0177 24 0,0301 1 E YVC1,CMP2,HMX1,SSQ1,SMF3,SKP1,SOD1,CSG2,PPZ2,ISU1,PTK2,COT1,PRX1,COS3,AHP1,RAV2,SLF1,GRX2,OCT1,GRX1,CNB1,IZH3,VPS45,VHS3 GO:0006595 7,8 polyamine metabolism 7 0,0011 3 0,0038 1 E ALD3,FMS1,ALD2 GO:0009308 5 amine metabolism 218 0,0338 29 0,0363 1 E ARO9,ALD3,PUT1,PHO2,MSY1,CAT2,CIT2,FMS1,GDH3,ASP3-3,FMT1,NAM2,CHA1,MSK1,ARO80,CAR2,ALD2,AGX1,TRP4,ASP3-4,MSR1,CIT1,MET22,MST1,GAD1,ARO10,PUT3,UGA2,ARG4 GO:0001308 8,12,11,7,6 loss of chromatin silencing during replicative cell aging 8 0,0012 2 0,0025 1 E RPD3,MPT5 GO:0000750 7,8,6 signal transduction during conjugation with cellular fusion 22 0,0034 7 0,0088 1 E STE18,STE11,MDG1,RGA2,PTP2,AFR1,STE5 GO:0007093 9,7 mitotic checkpoint 22 0,0034 4 0,005 1 E BUB3,PPH22,MPS1,MAD1 GO:0006265 7 DNA topological change 5 0,0008 1 0,0013 1 E PAP2 GO:0018344 11,1 protein geranylgeranylation 4 0,0006 1 0,0013 1 E BET4 GO:0009269 7,6 response to desiccation 10 0,0015 2 0,0025 1 E SIP18,STF2 GO:0000169 9,8 activation of MAPK activity during osmolarity sensing 1 0,0002 1 0,0013 1 E PBS2 GO:0042843 9,1 D-xylose catabolism 4 0,0006 3 0,0038 1 E YPR1,GRE3,GCY1 GO:0009231 8,9 riboflavin biosynthesis 6 0,0009 2 0,0025 1 E RIB4,RIB5 GO:0000723 8 telomere maintenance 45 0,007 10 0,0125 1 E RAD59,EST3,RAD50,MEC1,YRF1-2,SWD2,RAD52,YKU80,YKU70,XRS2 GO:0000726 8,7 non-recombinational repair 28 0,0043 10 0,0125 1 E RPD3,FYV6,RAD59,RAD50,DOA1,RAD1,RAD52,YKU80,YKU70,XRS2 GO:0000074 5 regulation of progression through cell cycle 140 0,0217 22 0,0276 1 E BUB3,POG1,PPH22,SIC1,OPY2,GRR1,GTS1,MEC1,MPS1,CDC37,BCK2,APC9,FAR10,TOR1,BMH2,CYR1,MAD1,GID8,BMH1,MPT5,FAR11,CLN3 GO:0030865 7 cortical cytoskeleton organization and biogenesis 16 0,0025 6 0,0075 1 E ARC15,HUA1,SCD5,ENT1,ENT3,ARC19 GO:0042493 6 response to drug 31 0,0048 8 0,01 1 E YRR1,MLF3,GTS1,SNG1,YAP1,YOR1,CIN5,YRM1 GO:0051348 5 negative regulation of transferase activity 6 0,0009 1 0,0013 1 E PTP2 GO:0006598 8,9 polyamine catabolism 3 0,0005 3 0,0038 1 E ALD3,FMS1,ALD2 GO:0009110 6 vitamin biosynthesis 38 0,0059 8 0,01 1 E RIB4,QNS1,RIB5,BNA1,BIO3,POS5,THI21,THI3 GO:0043241 6 protein complex disassembly 2 0,0003 1 0,0013 1 E PRP22 GO:0007029 6 ER organization and biogenesis 5 0,0008 1 0,0013 1 E MYO4 GO:0009072 7,6,8 aromatic amino acid family metabolism 21 0,0033 4 0,005 1 E ARO9,ARO80,TRP4,ARO10 GO:0007127 8 meiosis I 56 0,0087 13 0,0163 1 E ZIP1,AMA1,REC114,SPO11,MMS4,RAD50,MEC1,CST9,MSC1,RAD52,RIM4,MUS81,XRS2 GO:0009144 8 purine nucleoside triphosphate metabolism 22 0,0034 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0005979 11,9,8,10,7 regulation of glycogen biosynthesis 5 0,0008 2 0,0025 1 E PCL6,PCL7 GO:0031570 7 DNA integrity checkpoint 17 0,0026 3 0,0038 1 E MEC1,BMH2,BMH1 GO:0046443 7,8 FAD metabolism 1 0,0002 1 0,0013 1 E FAD1 GO:0007531 4 mating type determination 23 0,0036 3 0,0038 1 E RAD1,RAD52,YKU80 GO:0006527 9,10,7,6 arginine catabolism 2 0,0003 1 0,0013 1 E CAR2 GO:0030148 8,7,9 sphingolipid biosynthesis 19 0,0029 3 0,0038 1 E LAG1,CSG2,SKN1 GO:0019541 7 propionate metabolism 5 0,0008 2 0,0025 1 E CIT3,PDH1 GO:0007124 4 pseudohyphal growth 48 0,0074 9 0,0113 1 E STE11,TPK1,RGA2,TPK2,BCY1,BMH2,BMH1,RAS2,DIA3 GO:0006818 5,6 hydrogen transport 24 0,0037 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0010133 10,9,11 proline catabolism to glutamate 2 0,0003 1 0,0013 1 E PUT1 GO:0006627 11,9,10 mitochondrial protein processing 5 0,0008 2 0,0025 1 E IMP1,OCT1 GO:0006301 8,7 postreplication repair 11 0,0017 3 0,0038 1 E HYS2,PAN3,RFA1 GO:0006734 10,9 NADH metabolism 6 0,0009 3 0,0038 1 E GUT2,MDH3,NDE1 GO:0006807 4 nitrogen compound metabolism 236 0,0366 33 0,0414 1 E ARO9,ALD3,ADY2,PUT1,PHO2,MSY1,CAT2,VID30,NPR1,UGA3,CIT2,FMS1,GDH3,ASP3-3,FMT1,NAM2,CHA1,MSK1,ARO80,CAR2,ALD2,AGX1,TRP4,ASP3-4,MSR1,CIT1,MET22,MST1,GAD1,ARO10,PUT3,UGA2,ARG4 GO:0042770 6 DNA damage response, signal transduction 14 0,0022 3 0,0038 1 E MEC1,BMH2,BMH1 GO:0051327 6 M phase of meiotic cell cycle 129 0,02 22 0,0276 1 E BDF1,ZIP1,AMA1,REC114,ADY2,SET3,SPO11,MMS4,RAD50,MEC1,CST9,MSC1,TOR1,SIF2,RCK2,RAD52,WTM1,RIM4,CYR1,MUS81,SDS24,XRS2 GO:0000187 8 activation of MAPK activity 1 0,0002 1 0,0013 1 E PBS2 GO:0015992 6,8,7,9 proton transport 24 0,0037 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0042158 8,7 lipoprotein biosynthesis 36 0,0056 5 0,0063 1 E SHR5,PBN1,FAA1,BET4,GPI19 GO:0042144 7,4 vacuole fusion, non-autophagic 22 0,0034 6 0,0075 1 E SEC17,VAM6,VAC8,YPT7,PBI2,CLN3 GO:0045835 9 negative regulation of meiosis 5 0,0008 2 0,0025 1 E SET3,SIF2 GO:0006302 8,7 double-strand break repair 41 0,0064 11 0,0138 1 E RPD3,FYV6,RAD59,RAD50,DOA1,RAD1,RAD52,YKU80,YKU70,RFA1,XRS2 GO:0000725 8,7 recombinational repair 19 0,0029 6 0,0075 1 E RAD59,RAD50,RAD52,YKU80,YKU70,XRS2 GO:0015939 8 pantothenate metabolism 8 0,0012 1 0,0013 1 E FMS1 GO:0009743 6,5 response to carbohydrate stimulus 6 0,0009 3 0,0038 1 E SNF3,RGT2,AZF1 GO:0030010 7,8,6 establishment of cell polarity 103 0,016 16 0,0201 1 E MLC1,SAC6,LAS17,ERV14,SEC6,SLG1,SEC10,RGA2,RHO3,THP1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1 GO:0000746 5 conjugation 105 0,0163 18 0,0226 1 E POG1,CMP2,STE18,OPY2,GRR1,STE11,MDG1,PRM5,KAR2,RGA2,FAR10,PTP2,CNB1,AFR1,PRM8,STE5,MPT5,FAR11 GO:0000196 8,7 MAPKKK cascade during cell wall biogenesis 4 0,0006 1 0,0013 1 E PKH2 GO:0046083 8 adenine metabolism 3 0,0005 1 0,0013 1 E ADE8 GO:0030447 3 filamentous growth 87 0,0135 16 0,0201 1 E SIP2,VPS60,STE11,TPK1,RIM21,RGA2,TPK2,CAP2,RIM20,BCY1,BMH2,TPM1,STE5,BMH1,RAS2,DIA3 GO:0007034 8,6,7 vacuolar transport 48 0,0074 13 0,0163 1 E SKP1,BRO1,PEP12,GGA1,RAV2,VTI1,VPS52,MRL1,VPS15,YPT7,PEP1,VPS45,PEP7 GO:0030004 7 monovalent inorganic cation homeostasis 32 0,005 5 0,0063 1 E SKP1,PPZ2,COS3,RAV2,VHS3 GO:0006470 8 protein amino acid dephosphorylation 26 0,004 6 0,0075 1 E GIP2,PPH22,PPG1,PTP2,YPI1,LTP1 GO:0016075 8 rRNA catabolism 4 0,0006 1 0,0013 1 E PAP2 GO:0000011 7 vacuole inheritance 15 0,0023 5 0,0063 1 E MLC1,VAC8,TPM2,TPM1,YPT7 GO:0009719 4 response to endogenous stimulus 183 0,0284 35 0,0439 1 E BDF1,SNF3,RPD3,FYV6,YIM1,RAD59,DDR48,RAD2,HYS2,RPH1,RAD18,MMS4,MAG1,RAD50,MEC1,PAN3,IMP2prime,DOA1,PHR1,RAD1,RAD6,EXO1,RAD52,RAD26,BMH2,YKU80,BMH1,MUS81,RGT2,YKU70,AZF1,HSM3,RFA1,TDP1,XRS2 GO:0016570 11,8 histone modification 59 0,0091 11 0,0138 1 E LEO1,SET3,CDC73,TRA1,SET2,EPL1,RAD6,SWD2,SIF2,AHC1,PAF1 GO:0031023 6 microtubule organizing center organization and biogenesis 13 0,002 2 0,0025 1 E MPS1,CDC37 GO:0030042 10,7,8 actin filament depolymerization 4 0,0006 3 0,0038 1 E AIP1,CAP2,CAP1 GO:0006390 8 transcription from mitochondrial promoter 3 0,0005 2 0,0025 1 E RPO41,RSF1 GO:0006123 9,11,8 mitochondrial electron transport, cytochrome c to oxygen 10 0,0015 3 0,0038 1 E COX6,COX8,COX4 GO:0006743 8 ubiquinone metabolism 9 0,0014 4 0,005 1 E COQ6,COQ9,COQ4,COQ3 GO:0009247 8,7,9 glycolipid biosynthesis 3 0,0005 1 0,0013 1 E CSG2 GO:0031204 12,10,8,11,9 posttranslational protein targeting to membrane, translocation 4 0,0006 1 0,0013 1 E KAR2 GO:0009250 9,8,7 glucan biosynthesis 19 0,0029 8 0,01 1 E GLC3,PCL6,GLC8,GLG2,GLG1,PCL7,GSY2,SKN1 GO:0043161 11,12 proteasomal ubiquitin-dependent protein catabolism 46 0,0071 9 0,0113 1 E CNE1,SHP1,SKP1,NPL4,GRR1,VID30,APC9,SEC12,QRI8 GO:0009303 8 rRNA transcription 2 0,0003 1 0,0013 1 E RSC9 GO:0000045 6 autophagic vacuole formation 1 0,0002 1 0,0013 1 E ATG9 GO:0006281 7,6 DNA repair 150 0,0232 28 0,0351 1 E BDF1,RPD3,FYV6,RAD59,DDR48,RAD2,HYS2,RPH1,RAD18,MMS4,MAG1,RAD50,PAN3,IMP2prime,DOA1,PHR1,RAD1,RAD6,EXO1,RAD52,RAD26,YKU80,MUS81,YKU70,HSM3,RFA1,TDP1,XRS2 GO:0009167 9 purine ribonucleoside monophosphate metabolism 17 0,0026 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0016485 8 protein processing 32 0,005 7 0,0088 1 E PBN1,DAP2,IMP1,OCT1,COX20,RIM20,STE24 GO:0000161 8,7 MAPKKK cascade during osmolarity sensing 9 0,0014 3 0,0038 1 E PBS2,SSK2,PTP2 GO:0018377 10,9 protein myristoylation 5 0,0008 1 0,0013 1 E FAA1 GO:0046467 7,6,8 membrane lipid biosynthesis 71 0,011 12 0,015 1 E TAZ1,AYR1,LAG1,SCT1,PBN1,CSG2,INO4,GPT2,CHO1,CKI1,GPI19,SKN1 GO:0046685 7 response to arsenic 6 0,0009 1 0,0013 1 E YAP1 GO:0006875 7 metal ion homeostasis 60 0,0093 12 0,015 1 E HMX1,SSQ1,SMF3,SOD1,CSG2,PPZ2,ISU1,COT1,COS3,SLF1,OCT1,IZH3 GO:0019566 8,9 arabinose metabolism 4 0,0006 3 0,0038 1 E YPR1,GRE3,GCY1 GO:0006085 8 acetyl-CoA biosynthesis 4 0,0006 2 0,0025 1 E ACS1,PDX1 GO:0006659 10,9,11 phosphatidylserine biosynthesis 1 0,0002 1 0,0013 1 E CHO1 GO:0009165 6,7 nucleotide biosynthesis 55 0,0085 14 0,0175 1 E ATP2,STF2,ATP5,QNS1,ADE16,BNA1,POS5,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0045010 9 actin nucleation 3 0,0005 2 0,0025 1 E ARC40,PFY1 GO:0006828 9,1 manganese ion transport 7 0,0011 1 0,0013 1 E MTM1 GO:0006273 10 lagging strand elongation 20 0,0031 3 0,0038 1 E HYS2,PRI1,RFA1 GO:0045053 6 protein retention in Golgi 20 0,0031 3 0,0038 1 E VPS5,PEP8,VPS15 GO:0006420 10,11,9 arginyl-tRNA aminoacylation 1 0,0002 1 0,0013 1 E MSR1 GO:0051085 9 chaperone cofactor dependent protein folding 1 0,0002 1 0,0013 1 E HSP104 GO:0016567 9 protein ubiquitination 51 0,0079 9 0,0113 1 E UBR1,UBC4,SKP1,GRR1,UBC8,APC9,UBI4,RAD6,BUL1 GO:0006688 9,8,10 glycosphingolipid biosynthesis 3 0,0005 1 0,0013 1 E CSG2 GO:0019725 4 cell homeostasis 108 0,0167 23 0,0288 1 E YVC1,CMP2,HMX1,SSQ1,SMF3,SKP1,SOD1,CSG2,PPZ2,ISU1,PTK2,COT1,PRX1,COS3,AHP1,RAV2,SLF1,GRX2,OCT1,GRX1,CNB1,IZH3,VHS3 GO:0046352 8 disaccharide catabolism 24 0,0037 3 0,0038 1 E NTH2,MAL12,NTH1 GO:0009063 7,8 amino acid catabolism 28 0,0043 10 0,0125 1 E PUT1,ASP3-3,CHA1,ARO80,CAR2,ASP3-4,GAD1,ARO10,PUT3,UGA2 GO:0006658 9,1 phosphatidylserine metabolism 3 0,0005 1 0,0013 1 E CHO1 GO:0019932 6 second-messenger-mediated signaling 28 0,0043 8 0,01 1 E YMR1,TAX4,PDE1,LSB6,RSF1,CYR1,DPL1,RAS2 GO:0019321 7,8 pentose metabolism 6 0,0009 4 0,005 1 E YPR1,XKS1,GRE3,GCY1 GO:0048278 6,7 vesicle docking 14 0,0022 5 0,0063 1 E SEC6,SEC10,EXO70,SEC15,PEP7 GO:0006744 9,8 ubiquinone biosynthesis 3 0,0005 2 0,0025 1 E COQ9,COQ3 GO:0006824 9,1 cobalt ion transport 2 0,0003 1 0,0013 1 E COT1 GO:0006083 7 acetate metabolism 7 0,0011 3 0,0038 1 E ALD6,ACS1,ACH1 GO:0009266 5 response to temperature stimulus 20 0,0031 6 0,0075 1 E LSP1,LRE1,SLG1,BCY1,PIL1,YDC1 GO:0048285 6 organelle fission 4 0,0006 2 0,0025 1 E DNM1,FIS1 GO:0000076 8 DNA replication checkpoint 5 0,0008 1 0,0013 1 E MEC1 GO:0009260 7,8 ribonucleotide biosynthesis 39 0,006 11 0,0138 1 E ATP2,STF2,ATP5,ADE16,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0000719 9,8 photoreactive repair 1 0,0002 1 0,0013 1 E PHR1 GO:0006101 9,7 citrate metabolism 4 0,0006 3 0,0038 1 E CIT2,CIT3,CIT1 GO:0006290 8,7 pyrimidine dimer repair 1 0,0002 1 0,0013 1 E PHR1 GO:0007624 4 ultradian rhythm 1 0,0002 1 0,0013 1 E GTS1 GO:0006783 8,7 heme biosynthesis 14 0,0022 2 0,0025 1 E COX15,HEM15 GO:0018319 11,1 protein amino acid myristoylation 5 0,0008 1 0,0013 1 E FAA1 GO:0000706 10,9,12,11 meiotic DNA double-strand break processing 3 0,0005 1 0,0013 1 E RAD50 GO:0051276 6 chromosome organization and biogenesis 255 0,0395 35 0,0439 1 E BDF1,RPD3,LEO1,YAF9,RAD59,PAP2,SET3,CDC46,SKP1,ISW1,EST3,SWI1,RAD50,MEC1,PNC1,CDC73,YRF1-2,TRA1,SET2,EPL1,HST3,RAD6,SWD2,SIF2,RSC9,PHO23,RAD52,AHC1,PAF1,YKU80,MPT5,YKU70,SNF5,QRI8,XRS2 GO:0006307 8,7 DNA dealkylation 3 0,0005 1 0,0013 1 E MAG1 GO:0006515 9,1 misfolded or incompletely synthesized protein catabolism 22 0,0034 4 0,005 1 E CNE1,NPL4,SEC12,QRI8 GO:0030468 8,9,7 establishment of cell polarity (sensu Fungi) 103 0,016 16 0,0201 1 E MLC1,SAC6,LAS17,ERV14,SEC6,SLG1,SEC10,RGA2,RHO3,THP1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1 GO:0043173 6 nucleotide salvage 2 0,0003 1 0,0013 1 E PNC1 GO:0006811 5,6 ion transport 107 0,0166 16 0,0201 1 E ISA2,MTM1,ATP2,STF2,PMP3,ATP5,COT1,ENA2,SCO2,INH1,ATP15,PIC2,ATP16,BSD2,ATP3,ATP17 GO:0007118 7,5,6 budding cell apical bud growth 11 0,0017 4 0,005 1 E MLC1,RGA2,TPM2,TPM1 GO:0050794 3 regulation of cellular process 568 0,088 76 0,0952 1 E MAL13,BUB3,POG1,RPD3,FYV10,COX14,YRR1,PPH22,SPT2,RMD5,SNF4,YAF9,SIC1,OPY2,CDC46,PCL6,GRR1,RPH1,VID30,UGA3,PRX1,JSN1,GTS1,MEC1,CCL1,PNC1,INO4,MPS1,AHP1,AVO2,CDC37,UBC8,DHH1,TRA1,SET2,BCK2,SLF1,GRX2,OAF1,CAP2,EPL1,APC9,HST3,FAR10,TOR1,ECM32,SIF2,RSC9,MUB1,ARO80,DCS1,GRX1,PCL7,EAP1,AFR1,CAP1,AVO1,SWI5,BMH2,MAL33,CIN5,PRP45,YKU80,CYR1,YRM1,MAD1,GID8,BMH1,MPT5,YKU70,AZF1,FAR11,PUT3,CLN3,CSR2,PHB1 GO:0009126 8 purine nucleoside monophosphate metabolism 18 0,0028 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0000147 10,9 actin cortical patch assembly 15 0,0023 5 0,0063 1 E ARC15,HUA1,ENT1,ENT3,ARC19 GO:0045944 10 positive regulation of transcription from RNA polymerase II promoter 48 0,0074 6 0,0075 1 E YRR1,INO4,ARO80,PRP45,YRM1,PUT3 GO:0051246 6,5 regulation of protein metabolism 46 0,0071 12 0,015 1 E COX14,SKP1,RAV2,SLF1,CAP2,MRK1,ECM32,EAP1,CAP1,TFS1,PBI2,PHB1 GO:0044260 5 cellular macromolecule metabolism 1448 0,2244 193 0,2419 1 E SSA2,GIP2,SCL1,CBS2,MEF2,SIP2,ULA1,PRE7,UBR1,RPN11,RPN7,RPD3,RPT1,SHR5,CNE1,PRP5,COX15,SHP1,MDJ1,HSP82,LEO1,GLC3,PUP2,COX14,MRPL1,SIZ1,PPH22,PTH1,YPT1,PRE10,RPT2,MSY1,RPN5,LUC7,RSM23,RPT3,ASI2,ATP10,UBC4,PBN1,MRPS18,DDI1,SET3,UBX7,SLT2,PKH2,AIP1,SKP1,RPL5,LAS17,RUP1,NTA1,PCL6,KNS1,NPL4,ALG2,UBP15,GLC8,SSE1,FAA1,CBP4,UFD1,GRR1,BET4,STE11,GSF2,AHA1,VID30,RPN9,UBP6,AOS1,GLG2,MRPL28,TPK1,BRO1,STI1,PPG1,PMT2,SWS2,SSE2,UFD2,KRE9,GLG1,MRP20,GPH1,DAP2,MSF1,SAM50,MPD1,IST1,CDC73,ECM10,SGA1,FMT1,RIM11,UBC8,NAM2,HSP104,RAV2,PBS2,TRA1,IMP1,SET2,PSK2,CPR6,PPM1,SLF1,DOA1,ILS1,TPK2,SSK2,CAP2,HSP78,EPL1,HCH1,SSA4,APC9,SSA3,OCT1,ALG13,UBI4,FMC1,PTP2,MRK1,RAD6,RPN3,CMK1,SWD2,ECM32,SIF2,RCK2,SSC1,MSK1,TPM2,RSE1,RAD52,KIN82,PUP1,COX20,PCL7,RIM20,UBA3,PET123,EAP1,PEX19,CAP1,MRP8,RPN6,HSC82,BMH2,VPS15,MRPL16,TPM1,SEC12,MSR1,HSP26,AHC1,RSM18,PAF1,TFS1,MDM10,YMR31,YPI1,ECM14,UBP2,PFY1,BUL1,GSY2,UBX6,MRP51,KTR4,BMH1,MST1,PBI2,UGP1,YPK1,SSA1,PRE1,MRPL31,HYP2,YPK2,UBX5,LTP1,VPS45,RSM28,QRI8,GPI19,PHB1,SKN1,GDB1,STE24,RPN14,QCR7 GO:0000372 11 Group I intron splicing 7 0,0011 1 0,0013 1 E NAM2 GO:0006166 7,9 purine ribonucleoside salvage 6 0,0009 1 0,0013 1 E ISN1 GO:0046084 9,8 adenine biosynthesis 1 0,0002 1 0,0013 1 E ADE8 GO:0001302 6,5 replicative cell aging 33 0,0051 10 0,0125 1 E SIP2,RPD3,ATP2,LAG1,LAG2,RTG2,PNC1,RAS2,MPT5,PHB1 GO:0015908 6,7 fatty acid transport 4 0,0006 2 0,0025 1 E PXA2,PXA1 GO:0006654 8,10,9,11 phosphatidic acid biosynthesis 1 0,0002 1 0,0013 1 E AYR1 GO:0006752 7 group transfer coenzyme metabolism 44 0,0068 10 0,0125 1 E ATP2,STF2,ATP5,FMS1,INH1,ATP15,ATP16,ATP3,ATP17,VHS3 GO:0006768 6,7 biotin metabolism 4 0,0006 1 0,0013 1 E BIO3 GO:0006739 10,9 NADP metabolism 13 0,002 5 0,0063 1 E ZWF1,TKL2,SOL4,IDP3,POS5 GO:0051084 8 posttranslational protein folding 2 0,0003 2 0,0025 1 E ECM10,HSP104 GO:0045003 10,9 double-strand break repair via synthesis-dependent strand annealing 11 0,0017 2 0,0025 1 E RAD50,RAD52 GO:0009152 8,9 purine ribonucleotide biosynthesis 38 0,0059 11 0,0138 1 E ATP2,STF2,ATP5,ADE16,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0006280 7 mutagenesis 7 0,0011 1 0,0013 1 E HYS2 GO:0046854 8,10,9,11 phosphoinositide phosphorylation 4 0,0006 1 0,0013 1 E LSB6 GO:0045786 6 negative regulation of progression through cell cycle 11 0,0017 4 0,005 1 E OPY2,GRR1,FAR10,FAR11 GO:0007047 6 cell wall organization and biogenesis 141 0,0218 23 0,0288 1 E ECM2,ECM21,ECM18,SLT2,PKH2,MTL1,ECM4,LRE1,KRE9,FMP45,TUS1,TAX4,SLG1,CNB1,SBE22,MYO3,ECM30,ECM14,ROT1,MPT5,SSD1,CSR2,SKN1 GO:0009966 5,4 regulation of signal transduction 2 0,0003 1 0,0013 1 E AFR1 GO:0043119 4 positive regulation of physiological process 71 0,011 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0019323 8,9 pentose catabolism 5 0,0008 4 0,005 1 E YPR1,XKS1,GRE3,GCY1 GO:0019365 9,7,8 pyridine nucleotide salvage 2 0,0003 1 0,0013 1 E PNC1 GO:0009408 6,5 response to heat 17 0,0026 6 0,0075 1 E LSP1,LRE1,SLG1,BCY1,PIL1,YDC1 GO:0006643 6,7 membrane lipid metabolism 106 0,0164 20 0,0251 1 E TAZ1,AYR1,LAG1,SCT1,PBN1,LPP1,CSG2,INO4,LSB6,DPP1,GPT2,YDC1,DPL1,YPK1,CHO1,YPC1,CKI1,GPI19,SKN1,SPO14 GO:0046148 6 pigment biosynthesis 14 0,0022 2 0,0025 1 E COX15,HEM15 GO:0006544 8,9 glycine metabolism 6 0,0009 1 0,0013 1 E AGX1 GO:0009991 4,5 response to extracellular stimulus 20 0,0031 7 0,0088 1 E SIP2,PHO2,PRB1,SIP5,ASP3-3,ASP3-4,DPL1 GO:0040020 8 regulation of meiosis 20 0,0031 4 0,005 1 E SET3,SIF2,RCK2,WTM1 GO:0006071 7 glycerol metabolism 8 0,0012 3 0,0038 1 E GUT1,TCO89,DAK2 GO:0048017 8 inositol lipid-mediated signaling 13 0,002 3 0,0038 1 E YMR1,TAX4,LSB6 GO:0006163 7 purine nucleotide metabolism 46 0,0071 11 0,0138 1 E ATP2,STF2,ATP5,ADE16,INH1,ATP15,ADE8,ATP16,ATP3,ADE2,ATP17 GO:0007231 6 osmosensory signaling pathway 15 0,0023 4 0,005 1 E PBS2,SSK2,PTP2,RCK2 GO:0006343 13,8,11,6 establishment of chromatin silencing 2 0,0003 1 0,0013 1 E CDC46 GO:0045861 9,7,8 negative regulation of proteolysis 2 0,0003 1 0,0013 1 E PHB1 GO:0006081 5 aldehyde metabolism 19 0,0029 5 0,0063 1 E CIT2,ALD2,GLO4,GLO2,MDH3 GO:0006880 9,10,6 intracellular sequestering of iron ion 2 0,0003 2 0,0025 1 E SSQ1,SMF3 GO:0045185 5 maintenance of protein localization 29 0,0045 4 0,005 1 E VPS5,ERD2,PEP8,VPS15 GO:0042726 7 riboflavin and derivative metabolism 8 0,0012 3 0,0038 1 E RIB4,RIB5,FAD1 GO:0006464 7 protein modification 431 0,0668 70 0,0877 1 E GIP2,SIP2,ULA1,UBR1,RPD3,SHR5,LEO1,SIZ1,PPH22,UBC4,PBN1,SET3,SLT2,PKH2,SKP1,RUP1,NTA1,KNS1,ALG2,UBP15,FAA1,GRR1,BET4,STE11,UBP6,AOS1,TPK1,PPG1,PMT2,DAP2,CDC73,RIM11,UBC8,PBS2,TRA1,IMP1,SET2,PSK2,PPM1,TPK2,SSK2,EPL1,APC9,OCT1,ALG13,UBI4,PTP2,MRK1,RAD6,CMK1,SWD2,SIF2,RCK2,KIN82,COX20,RIM20,UBA3,VPS15,AHC1,PAF1,YPI1,UBP2,BUL1,KTR4,UGP1,YPK1,YPK2,LTP1,GPI19,STE24 GO:0006874 8 calcium ion homeostasis 6 0,0009 1 0,0013 1 E CSG2 GO:0051596 7 methylglyoxal catabolism 3 0,0005 2 0,0025 1 E GLO4,GLO2 GO:0043174 6 nucleoside salvage 6 0,0009 1 0,0013 1 E ISN1 GO:0051349 5 positive regulation of lyase activity 1 0,0002 1 0,0013 1 E RAS2 GO:0031146 12,13 SCF-dependent proteasomal ubiquitin-dependent protein catabolism 7 0,0011 2 0,0025 1 E SKP1,GRR1 GO:0030847 10 transcription termination from Pol II promoter, RNA polymerase(A)-independent 8 0,0012 1 0,0013 1 E SWD2 GO:0051300 7 spindle pole body organization and biogenesis 13 0,002 2 0,0025 1 E MPS1,CDC37 GO:0000075 6 cell cycle checkpoint 47 0,0073 7 0,0088 1 E BUB3,PPH22,MEC1,MPS1,BMH2,MAD1,BMH1 GO:0000077 8,7 DNA damage checkpoint 13 0,002 3 0,0038 1 E MEC1,BMH2,BMH1 GO:0007041 8,9,6,7 lysosomal transport 1 0,0002 1 0,0013 1 E VTI1 GO:0019482 8,9 beta-alanine metabolism 2 0,0003 2 0,0025 1 E ALD3,ALD2 GO:0000727 10,9 double-strand break repair via break-induced replication 6 0,0009 4 0,005 1 E RAD59,RAD50,RAD52,XRS2 GO:0051156 9,1 glucose 6-phosphate metabolism 2 0,0003 1 0,0013 1 E PGM2 GO:0007114 5,4 cell budding 77 0,0119 16 0,0201 1 E MLC1,SAC6,PPH22,LAS17,ERV14,SEC6,SEC10,RGA2,MUB1,TPM2,EXO70,MYO3,TPM1,SEC15,PFY1,REH1 GO:0009251 9,8 glucan catabolism 9 0,0014 5 0,0063 1 E PCL6,GPH1,SGA1,PCL7,GDB1 GO:0008277 7,6,5 regulation of G-protein coupled receptor protein signaling pathway 1 0,0002 1 0,0013 1 E AFR1 GO:0000390 10,12,7 spliceosome disassembly 2 0,0003 1 0,0013 1 E PRP22 GO:0006102 9,7 isocitrate metabolism 5 0,0008 1 0,0013 1 E IDP3 GO:0019660 8 glycolytic fermentation 6 0,0009 1 0,0013 1 E NDE1 GO:0008361 6,5 regulation of cell size 12 0,0019 4 0,005 1 E WHI5,WHI4,AVO2,AVO1 GO:0051235 4 maintenance of localization 31 0,0048 6 0,0075 1 E SSQ1,SMF3,VPS5,ERD2,PEP8,VPS15 GO:0042176 7,8,6 regulation of protein catabolism 3 0,0005 1 0,0013 1 E MRK1 GO:0000391 11,13,8 U2-type spliceosome disassembly 2 0,0003 1 0,0013 1 E PRP22 GO:0043406 7 positive regulation of MAPK activity 1 0,0002 1 0,0013 1 E PBS2 GO:0016558 11,8,9,7,10 protein import into peroxisome matrix 6 0,0009 2 0,0025 1 E PEX25,PEX12 GO:0006638 6,7 neutral lipid metabolism 4 0,0006 1 0,0013 1 E TGL4 GO:0000266 7 mitochondrial fission 3 0,0005 2 0,0025 1 E DNM1,FIS1 GO:0051238 5 sequestering of metal ion 2 0,0003 2 0,0025 1 E SSQ1,SMF3 GO:0031494 8,6 regulation of mating type switching 1 0,0002 1 0,0013 1 E YKU80 GO:0043412 6 biopolymer modification 567 0,0879 74 0,0927 1 E GIP2,SIP2,ULA1,UBR1,YMR1,RPD3,SHR5,LEO1,SIZ1,PPH22,TAD3,UBC4,PBN1,SET3,SLT2,PKH2,SKP1,RUP1,NTA1,KNS1,ALG2,UBP15,FAA1,GRR1,BET4,STE11,UBP6,AOS1,TPK1,PPG1,PMT2,DAP2,CDC73,RIM11,UBC8,PBS2,TRA1,IMP1,SET2,PSK2,PPM1,TPK2,SSK2,EPL1,APC9,LSB6,OCT1,ALG13,UBI4,PTP2,MRK1,RAD6,CMK1,SWD2,SIF2,RCK2,KIN82,COX20,RIM20,UBA3,VPS15,AHC1,PAF1,YPI1,TRM12,UBP2,BUL1,KTR4,UGP1,YPK1,YPK2,LTP1,GPI19,STE24 GO:0006512 8 ubiquitin cycle 69 0,0107 13 0,0163 1 E UBR1,UBC4,SKP1,RUP1,UBP15,GRR1,UBP6,UBC8,APC9,UBI4,RAD6,UBP2,BUL1 GO:0006552 9,1 leucine catabolism 2 0,0003 1 0,0013 1 E ARO10 GO:0006111 10,11,9,8,7 regulation of gluconeogenesis 11 0,0017 5 0,0063 1 E FYV10,RMD5,VID30,UBC8,GID8 GO:0030162 8,7,6 regulation of proteolysis 4 0,0006 3 0,0038 1 E TFS1,PBI2,PHB1 GO:0007121 6,8,10,11,9,5 bipolar bud site selection 32 0,005 8 0,01 1 E SAC6,LAS17,SEC6,SEC10,EXO70,MYO3,SEC15,PFY1 GO:0006754 8,10,7,9,11 ATP biosynthesis 20 0,0031 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0000730 8,10,11,7 DNA recombinase assembly 5 0,0008 1 0,0013 1 E RAD52 GO:0006431 10,11,9 methionyl-tRNA aminoacylation 3 0,0005 1 0,0013 1 E FMT1 GO:0000271 8,7,6 polysaccharide biosynthesis 28 0,0043 8 0,01 1 E GLC3,PCL6,GLC8,GLG2,GLG1,PCL7,GSY2,SKN1 GO:0051188 6 cofactor biosynthesis 71 0,011 18 0,0226 1 E COX15,ATP2,STF2,ATP5,QNS1,COQ9,FMS1,FAD1,BNA1,POS5,INH1,ATP15,COQ3,ATP16,HEM15,ATP3,ATP17,VHS3 GO:0030866 9,8 cortical actin cytoskeleton organization and biogenesis 16 0,0025 6 0,0075 1 E ARC15,HUA1,SCD5,ENT1,ENT3,ARC19 GO:0006481 9,1 C-terminal protein amino acid methylation 1 0,0002 1 0,0013 1 E PPM1 GO:0008333 9,10,8,7 endosome to lysosome transport 1 0,0002 1 0,0013 1 E VTI1 GO:0015891 5,6 siderophore transport 9 0,0014 2 0,0025 1 E FIT2,FIT3 GO:0050793 3 regulation of development 2 0,0003 1 0,0013 1 E MUB1 GO:0006144 7 purine base metabolism 16 0,0025 3 0,0038 1 E PHO2,ADE8,ADE2 GO:0006537 9,1 glutamate biosynthesis 13 0,002 4 0,005 1 E PUT1,CIT2,GDH3,CIT1 GO:0006530 9,1 asparagine catabolism 5 0,0008 2 0,0025 1 E ASP3-3,ASP3-4 GO:0009123 7 nucleoside monophosphate metabolism 19 0,0029 3 0,0038 1 E ADE16,ADE8,ADE2 GO:0051329 6 interphase of mitotic cell cycle 86 0,0133 15 0,0188 1 E WHI5,SAP155,POG1,PPH22,SIC1,SKP1,PTK2,GRR1,BCK2,VHS2,TOR1,SWI5,GID8,CLN3,VHS3 GO:0031281 5 positive regulation of cyclase activity 1 0,0002 1 0,0013 1 E RAS2 GO:0006741 9,8,11,10 NADP biosynthesis 1 0,0002 1 0,0013 1 E POS5 GO:0046034 6,1 ATP metabolism 20 0,0031 8 0,01 1 E ATP2,STF2,ATP5,INH1,ATP15,ATP16,ATP3,ATP17 GO:0000321 7,8,6 re-entry into mitotic cell cycle after pheromone arrest 3 0,0005 2 0,0025 1 E POG1,MPT5 GO:0007188 8,9 G-protein signaling, coupled to cAMP nucleotide second messenger 4 0,0006 2 0,0025 1 E CYR1,RAS2 GO:0006012 8,9 galactose metabolism 8 0,0012 2 0,0025 1 E GAL7,GAL10 GO:0051244 4 regulation of cellular physiological process 566 0,0877 75 0,094 1 E MAL13,BUB3,POG1,RPD3,FYV10,COX14,YRR1,PPH22,SPT2,RMD5,SNF4,YAF9,SIC1,OPY2,CDC46,PCL6,GRR1,RPH1,VID30,UGA3,PRX1,JSN1,GTS1,MEC1,CCL1,PNC1,INO4,MPS1,AHP1,AVO2,CDC37,UBC8,DHH1,TRA1,SET2,BCK2,SLF1,GRX2,OAF1,CAP2,EPL1,APC9,HST3,FAR10,TOR1,ECM32,SIF2,RSC9,MUB1,ARO80,DCS1,GRX1,PCL7,EAP1,CAP1,AVO1,SWI5,BMH2,MAL33,CIN5,PRP45,YKU80,CYR1,YRM1,MAD1,GID8,BMH1,MPT5,YKU70,AZF1,FAR11,PUT3,CLN3,CSR2,PHB1 GO:0009653 3 morphogenesis 144 0,0223 23 0,0288 1 E MLC1,SAC6,WHI5,LAS17,ERV14,GTS1,WHI4,SEC6,AVO2,SLG1,SEC10,RGA2,RNY1,RHO3,THP1,TPM2,EXO70,AFR1,AVO1,MYO3,TPM1,SEC15,PFY1 GO:0048519 3 negative regulation of biological process 178 0,0276 24 0,0301 1 E RPD3,FYV10,SPT2,RMD5,YAF9,OPY2,CDC46,GRR1,RPH1,VID30,CCL1,PNC1,UBC8,CAP2,HST3,FAR10,PTP2,SIF2,CAP1,YKU80,GID8,YKU70,FAR11,PHB1 GO:0016478 10,9,8 negative regulation of translation 4 0,0006 2 0,0025 1 E COX14,EAP1 GO:0007264 6 small GTPase mediated signal transduction 55 0,0085 12 0,015 1 E SHR5,TPK1,SLG1,RGA2,TPK2,RHO3,BMH2,IRA2,CYR1,BMH1,RAS2,BAG7 GO:0006771 8 riboflavin metabolism 6 0,0009 2 0,0025 1 E RIB4,RIB5 GO:0045047 10,8,6,9,7 protein targeting to ER 28 0,0043 4 0,005 1 E KAR2,SSA4,SSA3,SSA1 GO:0000160 5 two-component signal transduction system (phosphorelay) 12 0,0019 3 0,0038 1 E PBS2,SSK2,PTP2 GO:0046519 8,9 sphingoid metabolism 9 0,0014 3 0,0038 1 E LAG1,YDC1,YPC1 GO:0045935 7 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 66 0,0102 10 0,0125 1 E RPD3,YRR1,UGA3,INO4,OAF1,ARO80,PRP45,YRM1,MPT5,PUT3 GO:0006885 5 regulation of pH 27 0,0042 2 0,0025 1 D SKP1,RAV2 GO:0016573 12,9 histone acetylation 28 0,0043 3 0,0038 1 D TRA1,EPL1,AHC1 GO:0042724 8 thiamin and derivative biosynthesis 20 0,0031 2 0,0025 1 D THI21,THI3 GO:0030641 8 hydrogen ion homeostasis 23 0,0036 2 0,0025 1 D SKP1,RAV2 GO:0015849 5,6 organic acid transport 51 0,0079 6 0,0075 1 D ADY2,JEN1,AVT3,MUP3,AGP2,DIP5 GO:0016126 7,8,9 sterol biosynthesis 29 0,0045 2 0,0025 1 D MCR1,ERG9 GO:0045896 8,9 regulation of transcription, mitotic 10 0,0015 1 0,0013 1 D CCL1 GO:0000083 8,1 G1/S-specific transcription in mitotic cell cycle 12 0,0019 1 0,0013 1 D POG1 GO:0015837 5,6 amine transport 48 0,0074 5 0,0063 1 D PTK2,AVT3,MUP3,AGP2,DIP5 GO:0009075 7,8 histidine family amino acid metabolism 14 0,0022 1 0,0013 1 D PHO2 GO:0042401 7,8 biogenic amine biosynthesis 19 0,0029 1 0,0013 1 D TRP4 GO:0000184 9 mRNA catabolism, nonsense-mediated decay 9 0,0014 1 0,0013 1 D DHH1 GO:0015674 7,8 di-, tri-valent inorganic cation transport 51 0,0079 4 0,005 1 D ISA2,MTM1,COT1,SCO2 GO:0007062 5 sister chromatid cohesion 28 0,0043 1 0,0013 1 D PAP2 GO:0006696 8,9,10 ergosterol biosynthesis 25 0,0039 2 0,0025 1 D MCR1,ERG9 GO:0042546 7,6 cell wall biosynthesis 20 0,0031 1 0,0013 1 D SKN1 GO:0046021 9,1 regulation of transcription from RNA polymerase II promoter, mitotic 9 0,0014 1 0,0013 1 D CCL1 GO:0006526 9,10,7,6 arginine biosynthesis 10 0,0015 1 0,0013 1 D ARG4 GO:0006352 8 transcription initiation 55 0,0085 4 0,005 1 D TFG1,CST6,CCL1,RTG1 GO:0009892 5 negative regulation of metabolism 157 0,0243 19 0,0238 1 D RPD3,FYV10,SPT2,RMD5,YAF9,CDC46,RPH1,VID30,CCL1,PNC1,UBC8,CAP2,HST3,SIF2,CAP1,YKU80,GID8,YKU70,PHB1 GO:0001510 8 RNA methylation 15 0,0023 1 0,0013 1 D TRM12 GO:0046219 8,9,7 indolalkylamine biosynthesis 10 0,0015 1 0,0013 1 D TRP4 GO:0008054 6,12,13 cyclin catabolism 12 0,0019 1 0,0013 1 D APC9 GO:0006402 8 mRNA catabolism 55 0,0085 4 0,005 1 D JSN1,DHH1,DCS1,MPT5 GO:0000122 10 negative regulation of transcription from RNA polymerase II promoter 41 0,0064 4 0,005 1 D SPT2,RPH1,CCL1,SIF2 GO:0050658 7,6,8 RNA transport 72 0,0112 7 0,0088 1 D NPL3,MEX67,THP1,PAP1,ASM4,RPB4,CRM1 GO:0009070 8,9 serine family amino acid biosynthesis 12 0,0019 1 0,0013 1 D AGX1 GO:0006473 8 protein amino acid acetylation 38 0,0059 3 0,0038 1 D TRA1,EPL1,AHC1 GO:0006611 10,8,9 protein export from nucleus 45 0,007 3 0,0038 1 D CSE1,ASM4,CRM1 GO:0051169 8,6,7 nuclear transport 103 0,016 10 0,0125 1 D NPL3,CSE1,MEX67,THP1,PAP1,MTR10,ASM4,RPB4,SSA1,CRM1 GO:0051452 10,7 cellular pH reduction 23 0,0036 2 0,0025 1 D SKP1,RAV2 GO:0006259 6 DNA metabolism 555 0,086 64 0,0802 1 D BDF1,REC114,RPD3,FYV6,ADY2,LEO1,YAF9,SSQ1,RAD59,PAP2,DDR48,SET3,CDC46,SPO11,RAD2,HYS2,RPH1,ISW1,CST6,SWI1,RAD18,PRI1,MMS4,MAG1,RAD50,MEC1,PNC1,CDC73,PAN3,YRF1-2,IMP2prime,MSC1,TRA1,SET2,MCM3,DOA1,EPL1,PHR1,RAD1,HST3,THP1,RAD6,SWD2,SIF2,RSC9,PHO23,EXO1,RAD52,RAD26,AHC1,PAF1,MUM2,RIM4,YKU80,MUS81,MPT5,YKU70,SNF5,HSM3,SDS24,RFA1,QRI8,TDP1,XRS2 GO:0009081 7,8 branched chain family amino acid metabolism 16 0,0025 1 0,0013 1 D ARO10 GO:0006260 7 DNA replication 103 0,016 10 0,0125 1 D SSQ1,CDC46,HYS2,PRI1,MCM3,EXO1,MUM2,RIM4,HSM3,RFA1 GO:0040029 3 regulation of gene expression, epigenetic 84 0,013 9 0,0113 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,MPT5,YKU70 GO:0007064 9,6,7 mitotic sister chromatid cohesion 19 0,0029 1 0,0013 1 D PAP2 GO:0000278 5 mitotic cell cycle 231 0,0358 21 0,0263 1 D WHI5,SAP155,BUB3,POG1,PPH22,SIC1,PAP2,SKP1,PTK2,GRR1,CCL1,MPS1,BCK2,VHS2,APC9,TOR1,SWI5,MAD1,GID8,CLN3,VHS3 GO:0000022 9,11 mitotic spindle elongation 16 0,0025 1 0,0013 1 D APC9 GO:0030261 7 chromosome condensation 11 0,0017 1 0,0013 1 D PAP2 GO:0008202 6,7 steroid metabolism 45 0,007 5 0,0063 1 D OSH6,MCR1,ERG9,DAP1,TGL1 GO:0008150 1 biological_process 6454 1 798 1 1 D ASR1,SSA2,BDF1,GIP2,SCL1,PEX8,CBS2,TFG1,VPS29,MLC1,ZIP1,SAC6,PGM2,GYP7,MEF2,ISA2,ADR1,WHI5,ARC40,ATG4,YCP4,SIP2,MAL13,PFK26,SIP18,SNF3,SRL3,AMA1,SAP155,SDH2,BUB3,USA1,ULA1,FRT2,TDH3,PRE7,UBR1,POG1,PNS1,RPN11,ARO9,NAB6,GLR1,YMR1,BDF2,REC114,RPN7,RPD3,YVC1,SYM1,ZWF1,NPL3,ALD3,RPT1,HOR7,FYV6,APS1,LSC1,SHR5,ADH2,CNE1,FMP16,PRP5,TAZ1,YPR1,MTM1,YPT35,MED4,DOG2,ECM2,COQ6,KIN1,PEX2,UIP4,PTC7,COX15,SMY1,SHP1,MDJ1,MTQ1,HSP82,FYV10,ADY2,ALD6,LEO1,PUT1,SHE2,ARC35,GLC3,COS1,PUP2,AYR1,LSP1,COX14,YRR1,CMP2,RFS1,MRPL1,RIB4,SIZ1,PPH22,FMP33,PTH1,MDM31,SNX41,MLF3,ACS1,NUS1,ARC15,RPB7,YPT1,PRE10,FIT2,NVJ1,HMX1,QCR8,SPG4,HUA1,PHO2,SFT2,TAD3,SPT2,COS2,RPT2,RMD5,MSY1,SNC1,ATP2,STE18,COX6,FOX2,YIM1,STF2,ZSP1,PMP3,ECM21,SNF4,CNN1,YAF9,ATP5,RTN2,CAT2,RPN5,NTH2,LUC7,RSM23,RPT3,ASI2,HMO1,SSQ1,SIC1,LAG1,ECM18,RAD59,SCT1,CPR8,PAP2,ATP10,PSP1,PAI3,BET3,OSH6,OPY2,DDR48,UBC4,MCR1,CET1,TDH2,TKL2,PBN1,MRPS18,QNS1,DDI1,PFK27,SPG3,SET3,UBX7,RIB5,ERJ5,SMF3,LPP1,CDC46,SLT2,SPO11,PKH2,MDH1,KGD1,AIP1,MAK32,SKP1,RPL5,LAS17,UIP3,ATG1,BCH1,ERG9,SOD1,RAD2,NPC2,RUP1,CRD1,NTA1,KIN2,JIP4,HYS2,VPS60,MAL12,CSG2,ARP8,EHT1,PCL6,ASK10,PPZ2,KNS1,ISU1,NPL4,ERV14,PDX1,QCR10,GUT1,ALG2,UBP15,KRE11,GLC8,PTK2,SSE1,COQ9,FAA1,DNM1,GND2,FMP13,MTL1,CBP4,UFD1,MCT1,ARP3,GRR1,TCB1,LAG2,BET4,SEC17,NDI1,STE11,ALD4,KRE29,RPH1,MDG1,JEN1,PRB1,PEX3,COT1,YIP4,SIP5,GSF2,AST2,ADP1,SNU71,VPS73,AHA1,PRM5,YPS6,XYL2,SOL4,SYN8,FMP22,VID30,RPN9,UBP6,ISW1,VPS5,CST6,APL1,OMS1,NPR1,AOS1,EST3,GLG2,MRPL28,UGA3,ECM4,ENA2,TPK1,PRX1,TCO89,CTS2,FBP26,BRO1,SWI1,MED8,RAD18,JSN1,NUD1,HXT6,HXT16,VAM6,YPS5,STI1,ZRG8,DLD1,PRI1,GTS1,AQY1,PEX22,PEX25,RTG2,LRE1,CUE3,CTT1,CIT2,PPG1,PMT2,PCL5,SWS2,YBP1,RIM21,BBC1,ATG9,NCE103,HXK1,MMS4,PEP12,APM2,SSE2,UFD2,ADE16,COX8,FMS1,MAG1,SDH1,RAD50,KRE9,CYB2,FMP45,MEC1,SCD5,TUS1,RIP1,QCR6,WHI4,CIT3,BOP2,COS3,SDS22,GLG1,NIT1,MRP20,GPB2,GDH3,CCL1,GPH1,DAP2,CSE1,RPO41,BET5,SEC6,HSP31,MSF1,KAR2,HXT5,PNC1,YME1,FAD1,ASP3-3,TAX4,SAM50,TOM6,MEX67,MPD1,IST1,INO4,CDC73,ECM10,VAB2,MPS1,SYP1,SGA1,NCE102,AHP1,BNA1,MSL5,PAN3,YRF1-2,FMT1,ATG17,FMP12,AFG1,YIP5,XBP1,FIT3,AVO2,TGL4,ETR1,IMP2prime,MYO4,CDC37,RIM11,UBC8,GGA1,CST9,SLG1,AVT3,NAM2,HSP104,MSC1,DHH1,UGX2,RAV2,ERR1,PBS2,VPS17,HMI1,TRA1,SEC9,XKS1,VAC8,IMP1,SEC10,GOS1,FMP30,MCH1,HXT7,VTI1,DAP1,SET2,ENO1,LDB17,PSK2,GEM1,MCM3,BCK2,SRY1,CPR6,PPM1,CUS2,PXA2,ERD2,YET1,IDP3,SLF1,GRX2,DOA1,ILS1,OAF1,VHS2,RGA2,TPK2,GPM1,SSK2,CAP2,HSP78,PDE1,EPL1,HCH1,SCO2,PEX5,PHR1,PDH1,PXA1,RNY1,RHO3,SSA4,LEE1,ACH1,TGL1,ENT5,APC9,COS111,CHA1,RAD1,HST3,FAR10,GTR2,LSB6,SSA3,OCT1,ALG13,UBI4,FMC1,MSB3,THP1,TPS1,BIO3,PTP2,TIM21,GAL7,MRK1,ISN1,POS5,RAD6,RPN3,CMK1,SWD2,SNX4,TOR1,ECM32,GRE3,SIF2,MBR1,TSL1,ARP2,RCK2,GAL10,RSC9,IPK1,STR2,SSC1,MUB1,MSK1,PHO23,ARO80,MUP3,TPM2,DCS1,COR1,VPS38,STB3,YPT52,SNG1,PRP4,EXO70,YAP1801,RSE1,LEM3,EXO1,THI21,VPS30,RAD52,INH1,GRX1,CAR2,HSV2,KIN82,SPC105,PUP1,COX20,NGR1,OM45,PTC5,ZTA1,CNB1,PRP12,RAD26,PCL7,RIM20,ATG7,FMP14,BCY1,ALD2,NSG2,PEX29,QRI5,VPS52,NEM1,ATP15,APA1,YHI9,YET3,SBE22,UBA3,EMI2,UBP11,PET123,EAP1,DLD3,ENO2,SCP1,PEX19,AFR1,CAP1,YAP1,PAP1,AVO1,GLO4,AGX1,PRM8,ATG12,ENT1,MRP8,MRL1,DIT1,DAK2,THI3,RPN6,ATG19,VMR1,COS4,MYO3,PIC2,PEP8,RTG1,SWI5,HSC82,FIS1,QCR9,BMH2,TSC13,POP5,IRA2,FMP21,VPS15,TRP4,UBX3,MRPL16,TPM1,LSB1,PIL1,SEC12,DPP1,COQ4,ASP3-4,PAU7,MDM34,MSR1,FMP46,YOR1,OKP1,HSP26,HAP2,WTM1,DCS2,PTM1,MCX1,CIT1,ADE8,AHC1,RSM18,MAL33,CUE5,SEC15,PAF1,COX4,YPT7,ENT3,ECM30,TFS1,GPT2,AGP2,PHM8,MUM2,TRE2,MDM10,COQ3,NTH1,FUN19,YMR31,IZH3,YDC1,STE5,YPI1,TPS3,GUT2,TRM12,FMP37,CHL4,ATP16,MET22,RCY1,ECM14,CIN5,UBP2,PRP45,RSF1,ROT1,RIM4,MDR1,PEX12,YKU80,MTR10,CYR1,HAP5,PFY1,YRM1,PYK2,GPX1,FMP29,IQG1,BUL1,GSY2,MAD1,GID8,UBX6,YEN1,GLK1,MRP51,GRE2,SSP120,DPL1,KTR4,ASM4,GCY1,BMH1,DIP5,RPB4,KGD2,MUS81,MST1,PBI2,UGP1,FRE5,UTR4,PRP22,YPK1,SDH3,CHO1,RAS2,SSA1,BAG7,NUT2,PRE1,GAD1,RGT2,HEM15,MPT5,YKU70,AZF1,MRPL31,YTA7,ARO10,DIA3,SNF5,FAR11,PUT3,HYP2,PEP1,YPK2,REH1,ARA1,HSM3,SDS24,FMP10,YPC1,UBX5,CCP1,CAJ1,MPM1,QCR2,CKI1,CYC7,LAP4,ARC19,GTO3,YJU3,RFA1,VPS70,CLN3,EMP46,SSD1,GLO2,VPS21,BOR1,LTP1,BSD2,MMM1,INO1,VPS45,NYV1,HXT13,SSO1,ATP3,RCR2,RSM28,SEC28,CRM1,VPS8,ADE2,ATP17,VHS3,MDH3,TDH1,SHE10,UGA2,CSR2,QRI8,PEP7,GPI19,TVP18,PHB1,SKN1,PDX3,DSE3,GDB1,TDP1,STE24,SPO14,ARG4,EDE1,RPN14,LSB5,GAL11,COS6,QCR7,FMP34,APA2,SDH4,TMT1,CLC1,NDE1,XRS2 GO:0000070 8,6 mitotic sister chromatid segregation 55 0,0085 2 0,0025 1 D PAP2,APC9 GO:0006407 11,9,10,8 rRNA export from nucleus 26 0,004 1 0,0013 1 D ASM4 GO:0051030 8,7,9 snRNA transport 23 0,0036 1 0,0013 1 D ASM4 GO:0015698 7,8 inorganic anion transport 16 0,0025 1 0,0013 1 D PIC2 GO:0007051 9 spindle organization and biogenesis 43 0,0067 1 0,0013 1 D APC9 GO:0044271 6,5 nitrogen compound biosynthesis 108 0,0167 11 0,0138 1 D ALD3,PUT1,PHO2,CIT2,GDH3,ALD2,AGX1,TRP4,CIT1,MET22,ARG4 GO:0030001 7,8 metal ion transport 57 0,0088 6 0,0075 1 D ISA2,MTM1,COT1,ENA2,SCO2,BSD2 GO:0042257 8,9 ribosomal subunit assembly 52 0,0081 1 0,0013 1 D RPL5 GO:0009067 8,9 aspartate family amino acid biosynthesis 18 0,0028 1 0,0013 1 D MET22 GO:0006610 11,9,8,10 ribosomal protein import into nucleus 23 0,0036 1 0,0013 1 D ASM4 GO:0006913 8,6,7 nucleocytoplasmic transport 109 0,0169 11 0,0138 1 D NPL3,CSE1,MEX67,THP1,PAP1,MTR10,MAD1,ASM4,RPB4,SSA1,CRM1 GO:0006986 6,5 response to unfolded protein 12 0,0019 1 0,0013 1 D KAR2 GO:0006505 10,11 GPI anchor metabolism 24 0,0037 2 0,0025 1 D PBN1,GPI19 GO:0009076 8,9 histidine family amino acid biosynthesis 14 0,0022 1 0,0013 1 D PHO2 GO:0007059 4 chromosome segregation 104 0,0161 7 0,0088 1 D CNN1,PAP2,GLC8,SDS22,APC9,OKP1,CHL4 GO:0006272 10 leading strand elongation 14 0,0022 1 0,0013 1 D HYS2 GO:0006348 13,8,11,6 chromatin silencing at telomere 45 0,007 5 0,0063 1 D RPD3,YAF9,PNC1,HST3,SIF2 GO:0006725 5 aromatic compound metabolism 57 0,0088 7 0,0088 1 D ARO9,PHO2,ARO80,TRP4,ADE8,ARO10,ADE2 GO:0007088 8,6 regulation of mitosis 48 0,0074 4 0,005 1 D BUB3,PPH22,MPS1,MAD1 GO:0006401 7 RNA catabolism 64 0,0099 5 0,0063 1 D PAP2,JSN1,DHH1,DCS1,MPT5 GO:0051029 8,7,9 rRNA transport 26 0,004 1 0,0013 1 D ASM4 GO:0006997 6 nuclear organization and biogenesis 49 0,0076 3 0,0038 1 D KAR2,NEM1,ASM4 GO:0000741 7 karyogamy 12 0,0019 1 0,0013 1 D KAR2 GO:0042255 7,8 ribosome assembly 64 0,0099 1 0,0013 1 D RPL5 GO:0016481 8 negative regulation of transcription 128 0,0198 11 0,0138 1 D RPD3,SPT2,YAF9,CDC46,RPH1,CCL1,PNC1,HST3,SIF2,YKU80,YKU70 GO:0030384 9,1 phosphoinositide metabolism 31 0,0048 3 0,0038 1 D PBN1,LSB6,GPI19 GO:0051052 7 regulation of DNA metabolism 21 0,0033 1 0,0013 1 D YKU80 GO:0006820 6,7 anion transport 17 0,0026 1 0,0013 1 D PIC2 GO:0009228 8,9 thiamin biosynthesis 19 0,0029 2 0,0025 1 D THI21,THI3 GO:0042430 6 indole and derivative metabolism 10 0,0015 1 0,0013 1 D TRP4 GO:0031509 12 telomeric heterochromatin formation 45 0,007 5 0,0063 1 D RPD3,YAF9,PNC1,HST3,SIF2 GO:0006547 8,9 histidine metabolism 14 0,0022 1 0,0013 1 D PHO2 GO:0007004 9 telomerase-dependent telomere maintenance 13 0,002 1 0,0013 1 D EST3 GO:0031324 6 negative regulation of cellular metabolism 150 0,0232 17 0,0213 1 D RPD3,FYV10,SPT2,RMD5,YAF9,CDC46,RPH1,VID30,CCL1,PNC1,UBC8,HST3,SIF2,YKU80,GID8,YKU70,PHB1 GO:0045851 6 pH reduction 23 0,0036 2 0,0025 1 D SKP1,RAV2 GO:0006353 8 transcription termination 17 0,0026 1 0,0013 1 D SWD2 GO:0051028 8,7,9 mRNA transport 62 0,0096 6 0,0075 1 D NPL3,MEX67,PAP1,ASM4,RPB4,CRM1 GO:0006826 9,1 iron ion transport 19 0,0029 1 0,0013 1 D ISA2 GO:0006399 7 tRNA metabolism 103 0,016 10 0,0125 1 D TAD3,MSY1,PAP2,FMT1,NAM2,MSK1,POP5,MSR1,TRM12,MST1 GO:0051128 5 regulation of cell organization and biogenesis 22 0,0034 2 0,0025 1 D CAP2,CAP1 GO:0006276 4 plasmid maintenance 9 0,0014 1 0,0013 1 D HMO1 GO:0009073 8,7,9 aromatic amino acid family biosynthesis 16 0,0025 1 0,0013 1 D TRP4 GO:0000027 9,1 ribosomal large subunit assembly and maintenance 39 0,006 1 0,0013 1 D RPL5 GO:0006310 7 DNA recombination 189 0,0293 18 0,0226 1 D REC114,RPD3,RAD59,SPO11,MMS4,RAD50,MEC1,YRF1-2,MSC1,RAD1,THP1,RAD52,RIM4,YKU80,MUS81,YKU70,RFA1,XRS2 GO:0009309 6,7 amine biosynthesis 108 0,0167 11 0,0138 1 D ALD3,PUT1,PHO2,CIT2,GDH3,ALD2,AGX1,TRP4,CIT1,MET22,ARG4 GO:0006367 9 transcription initiation from RNA polymerase II promoter 44 0,0068 4 0,005 1 D TFG1,CST6,CCL1,RTG1 GO:0006261 8 DNA-dependent DNA replication 80 0,0124 8 0,01 1 D SSQ1,CDC46,HYS2,PRI1,MCM3,EXO1,HSM3,RFA1 GO:0006357 9 regulation of transcription from RNA polymerase II promoter 181 0,028 19 0,0238 1 D POG1,YRR1,SPT2,SNF4,RPH1,UGA3,CCL1,INO4,TRA1,EPL1,SIF2,RSC9,ARO80,SWI5,CIN5,PRP45,YRM1,PUT3,CSR2 GO:0006487 10,9 protein amino acid N-linked glycosylation 44 0,0068 3 0,0038 1 D ALG2,ALG13,KTR4 GO:0007035 11,9,7,8 vacuolar acidification 23 0,0036 2 0,0025 1 D SKP1,RAV2 GO:0000103 7 sulfate assimilation 10 0,0015 1 0,0013 1 D MET22 GO:0006609 11,9,8,10 mRNA-binding (hnRNP) protein import into nucleus 25 0,0039 2 0,0025 1 D MTR10,ASM4 GO:0000114 8,1 G1-specific transcription in mitotic cell cycle 14 0,0022 1 0,0013 1 D SWI5 GO:0006608 11,9,8,10 snRNP protein import into nucleus 23 0,0036 1 0,0013 1 D ASM4 GO:0009100 7 glycoprotein metabolism 73 0,0113 5 0,0063 1 D ALG2,PMT2,ALG13,KTR4,UGP1 GO:0045892 9 negative regulation of transcription, DNA-dependent 124 0,0192 11 0,0138 1 D RPD3,SPT2,YAF9,CDC46,RPH1,CCL1,PNC1,HST3,SIF2,YKU80,YKU70 GO:0000226 8 microtubule cytoskeleton organization and biogenesis 85 0,0132 4 0,005 1 D ARC35,NUD1,APC9,SPC105 GO:0050657 6,7 nucleic acid transport 72 0,0112 7 0,0088 1 D NPL3,MEX67,THP1,PAP1,ASM4,RPB4,CRM1 GO:0043413 7 biopolymer glycosylation 67 0,0104 5 0,0063 1 D ALG2,PMT2,ALG13,KTR4,UGP1 GO:0007120 6,8,10,11,9,5 axial bud site selection 22 0,0034 2 0,0025 1 D ERV14,PFY1 GO:0045814 4 negative regulation of gene expression, epigenetic 79 0,0122 8 0,01 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,YKU70 GO:0006825 9,1 copper ion transport 13 0,002 1 0,0013 1 D SCO2 GO:0006772 8 thiamin metabolism 20 0,0031 2 0,0025 1 D THI21,THI3 GO:0042723 7 thiamin and derivative metabolism 22 0,0034 2 0,0025 1 D THI21,THI3 GO:0000096 7,8,6 sulfur amino acid metabolism 32 0,005 1 0,0013 1 D MET22 GO:0006338 10 chromatin remodeling 132 0,0205 14 0,0175 1 D BDF1,RPD3,YAF9,CDC46,ISW1,SWI1,PNC1,HST3,SIF2,RSC9,YKU80,MPT5,YKU70,SNF5 GO:0006607 11,9,8,10 NLS-bearing substrate import into nucleus 23 0,0036 1 0,0013 1 D ASM4 GO:0051170 9,7,8 nuclear import 46 0,0071 3 0,0038 1 D MTR10,ASM4,SSA1 GO:0007017 7 microtubule-based process 100 0,0155 4 0,005 1 D ARC35,NUD1,APC9,SPC105 GO:0006400 8 tRNA modification 36 0,0056 2 0,0025 1 D TAD3,TRM12 GO:0009112 6 nucleobase metabolism 33 0,0051 3 0,0038 1 D PHO2,ADE8,ADE2 GO:0007070 10,11 negative regulation of transcription from RNA polymerase II promoter, mitotic 9 0,0014 1 0,0013 1 D CCL1 GO:0016458 6 gene silencing 79 0,0122 8 0,01 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,YKU70 GO:0042244 5 spore wall assembly 39 0,006 2 0,0025 1 D AMA1,DIT1 GO:0000375 9 RNA splicing, via transesterification reactions 105 0,0163 11 0,0138 1 D USA1,PRP5,ECM2,LUC7,SNU71,MSL5,NAM2,CUS2,PRP4,RSE1,PRP22 GO:0051278 9,8,7 cell wall polysaccharide biosynthesis (sensu Fungi) 15 0,0023 1 0,0013 1 D SKN1 GO:0006506 10,11,9,12 GPI anchor biosynthesis 23 0,0036 2 0,0025 1 D PBN1,GPI19 GO:0000105 9,1 histidine biosynthesis 14 0,0022 1 0,0013 1 D PHO2 GO:0000279 5 M phase 257 0,0398 29 0,0363 1 D BDF1,ZIP1,AMA1,BUB3,REC114,ADY2,PPH22,PAP2,SET3,SPO11,MMS4,RAD50,MEC1,CCL1,MPS1,CST9,MSC1,APC9,TOR1,SIF2,RCK2,RAD52,WTM1,RIM4,CYR1,MAD1,MUS81,SDS24,XRS2 GO:0006568 8,9,7 tryptophan metabolism 10 0,0015 1 0,0013 1 D TRP4 GO:0006413 9,8 translational initiation 48 0,0074 4 0,005 1 D FMT1,MRP51,HYP2,RSM28 GO:0006888 9,7,6,8 ER to Golgi transport 76 0,0118 9 0,0113 1 D YPT1,BET3,ERV14,KRE11,SEC17,BET5,SEC12,EMP46,SEC28 GO:0000086 7 G2/M transition of mitotic cell cycle 25 0,0039 1 0,0013 1 D SKP1 GO:0009069 7,8 serine family amino acid metabolism 22 0,0034 2 0,0025 1 D CHA1,AGX1 GO:0000819 5 sister chromatid segregation 55 0,0085 2 0,0025 1 D PAP2,APC9 GO:0006378 10 mRNA polyadenylylation 18 0,0028 1 0,0013 1 D PAP1 GO:0043162 11,12 ubiquitin-dependent protein catabolism via the multivesicular body pathway 12 0,0019 1 0,0013 1 D UBC4 GO:0006284 8,7 base-excision repair 10 0,0015 1 0,0013 1 D HYS2 GO:0006397 8 mRNA processing 132 0,0205 15 0,0188 1 D USA1,PRP5,ECM2,LUC7,CET1,UFD1,SNU71,MSL5,PAN3,CUS2,SWD2,PRP4,RSE1,PAP1,PRP22 GO:0031507 11 heterochromatin formation 79 0,0122 8 0,01 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,YKU70 GO:0000742 8,7,5 karyogamy during conjugation with cellular fusion 10 0,0015 1 0,0013 1 D KAR2 GO:0006791 6 sulfur utilization 10 0,0015 1 0,0013 1 D MET22 GO:0009272 8,7 cell wall biosynthesis (sensu Fungi) 20 0,0031 1 0,0013 1 D SKN1 GO:0006350 6 transcription 484 0,075 55 0,0689 1 D TFG1,ADR1,MAL13,POG1,RPD3,MED4,LEO1,YRR1,RPB7,PHO2,SPT2,SNF4,YAF9,CDC46,ASK10,RPH1,CST6,UGA3,MED8,GTS1,CCL1,RPO41,PNC1,INO4,CDC73,TRA1,SET2,OAF1,EPL1,HST3,THP1,SWD2,SIF2,RSC9,ARO80,YAP1,RTG1,SWI5,HAP2,MAL33,PAF1,CIN5,PRP45,RSF1,YKU80,HAP5,YRM1,RPB4,NUT2,MPT5,YKU70,AZF1,PUT3,CSR2,GAL11 GO:0000398 9,11 nuclear mRNA splicing, via spliceosome 97 0,015 10 0,0125 1 D USA1,PRP5,ECM2,LUC7,SNU71,MSL5,CUS2,PRP4,RSE1,PRP22 GO:0007266 7 Rho protein signal transduction 17 0,0026 1 0,0013 1 D SLG1 GO:0030476 7,6 spore wall assembly (sensu Fungi) 39 0,006 2 0,0025 1 D AMA1,DIT1 GO:0042398 7,6 amino acid derivative biosynthesis 20 0,0031 1 0,0013 1 D TRP4 GO:0010038 7 response to metal ion 16 0,0025 1 0,0013 1 D AHP1 GO:0051168 9,7,8 nuclear export 86 0,0133 8 0,01 1 D NPL3,CSE1,MEX67,THP1,PAP1,ASM4,RPB4,CRM1 GO:0009119 7 ribonucleoside metabolism 10 0,0015 1 0,0013 1 D ISN1 GO:0010035 6 response to inorganic substance 20 0,0031 2 0,0025 1 D AHP1,YAP1 GO:0006817 8,9 phosphate transport 10 0,0015 1 0,0013 1 D PIC2 GO:0007007 7,8 inner mitochondrial membrane organization and biogenesis 13 0,002 1 0,0013 1 D TAZ1 GO:0006406 11,9,10,8 mRNA export from nucleus 62 0,0096 6 0,0075 1 D NPL3,MEX67,PAP1,ASM4,RPB4,CRM1 GO:0006408 11,9,10,8 snRNA export from nucleus 23 0,0036 1 0,0013 1 D ASM4 GO:0000054 11,8,9,10 ribosome export from nucleus 16 0,0025 1 0,0013 1 D CRM1 GO:0006586 7,8 indolalkylamine metabolism 10 0,0015 1 0,0013 1 D TRP4 GO:0006369 9 transcription termination from RNA polymerase II promoter 15 0,0023 1 0,0013 1 D SWD2 GO:0000041 8,9 transition metal ion transport 43 0,0067 4 0,005 1 D ISA2,MTM1,COT1,SCO2 GO:0009101 8,7 glycoprotein biosynthesis 72 0,0112 5 0,0063 1 D ALG2,PMT2,ALG13,KTR4,UGP1 GO:0006271 9 DNA strand elongation 30 0,0046 3 0,0038 1 D HYS2,PRI1,RFA1 GO:0048284 6 organelle fusion 17 0,0026 1 0,0013 1 D KAR2 GO:0046470 9,1 phosphatidylcholine metabolism 9 0,0014 1 0,0013 1 D CKI1 GO:0006270 9 DNA replication initiation 25 0,0039 3 0,0038 1 D CDC46,PRI1,MCM3 GO:0006891 9,7,6,8 intra-Golgi transport 21 0,0033 2 0,0025 1 D GOS1,VTI1 GO:0046489 10,9,11 phosphoinositide biosynthesis 24 0,0037 2 0,0025 1 D PBN1,GPI19 GO:0046112 7,6 nucleobase biosynthesis 21 0,0033 2 0,0025 1 D PHO2,ADE8 GO:0007052 8,1 mitotic spindle organization and biogenesis 42 0,0065 1 0,0013 1 D APC9 GO:0042278 7 purine nucleoside metabolism 9 0,0014 1 0,0013 1 D ISN1 GO:0019219 6 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 355 0,055 36 0,0451 1 D MAL13,POG1,RPD3,YRR1,SPT2,SNF4,YAF9,CDC46,RPH1,UGA3,JSN1,GTS1,CCL1,PNC1,INO4,DHH1,TRA1,SET2,OAF1,EPL1,HST3,SIF2,RSC9,ARO80,DCS1,SWI5,MAL33,CIN5,PRP45,YKU80,YRM1,MPT5,YKU70,AZF1,PUT3,CSR2 GO:0006606 10,8,7,9 protein import into nucleus 46 0,0071 3 0,0038 1 D MTR10,ASM4,SSA1 GO:0031145 12,13 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism 15 0,0023 1 0,0013 1 D APC9 GO:0007091 8 mitotic metaphase/anaphase transition 15 0,0023 1 0,0013 1 D APC9 GO:0030488 9 tRNA methylation 14 0,0022 1 0,0013 1 D TRM12 GO:0000377 10 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 98 0,0152 10 0,0125 1 D USA1,PRP5,ECM2,LUC7,SNU71,MSL5,CUS2,PRP4,RSE1,PRP22 GO:0019438 6 aromatic compound biosynthesis 17 0,0026 1 0,0013 1 D TRP4 GO:0009096 9,8,10 aromatic amino acid family biosynthesis, anthranilate pathway 10 0,0015 1 0,0013 1 D TRP4 GO:0006790 5 sulfur metabolism 57 0,0088 3 0,0038 1 D BIO3,STR2,MET22 GO:0006555 8,9,7 methionine metabolism 23 0,0036 1 0,0013 1 D MET22 GO:0051236 5 establishment of RNA localization 72 0,0112 7 0,0088 1 D NPL3,MEX67,THP1,PAP1,ASM4,RPB4,CRM1 GO:0000097 8,9,7 sulfur amino acid biosynthesis 9 0,0014 1 0,0013 1 D MET22 GO:0045449 7 regulation of transcription 324 0,0502 33 0,0414 1 D MAL13,POG1,RPD3,YRR1,SPT2,SNF4,YAF9,CDC46,RPH1,UGA3,GTS1,CCL1,PNC1,INO4,TRA1,SET2,OAF1,EPL1,HST3,SIF2,RSC9,ARO80,SWI5,MAL33,CIN5,PRP45,YKU80,YRM1,MPT5,YKU70,AZF1,PUT3,CSR2 GO:0006355 8 regulation of transcription, DNA-dependent 305 0,0473 31 0,0388 1 D MAL13,POG1,RPD3,YRR1,SPT2,SNF4,YAF9,CDC46,RPH1,UGA3,CCL1,PNC1,INO4,TRA1,SET2,EPL1,HST3,SIF2,RSC9,ARO80,SWI5,MAL33,CIN5,PRP45,YKU80,YRM1,MPT5,YKU70,AZF1,PUT3,CSR2 GO:0007020 9 microtubule nucleation 33 0,0051 2 0,0025 1 D NUD1,SPC105 GO:0046942 6,7 carboxylic acid transport 50 0,0077 6 0,0075 1 D ADY2,JEN1,AVT3,MUP3,AGP2,DIP5 GO:0008652 7,8 amino acid biosynthesis 99 0,0153 11 0,0138 1 D ALD3,PUT1,PHO2,CIT2,GDH3,ALD2,AGX1,TRP4,CIT1,MET22,ARG4 GO:0006333 9 chromatin assembly or disassembly 100 0,0155 9 0,0113 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,YKU70,QRI8 GO:0043283 5 biopolymer metabolism 1593 0,2468 196 0,2456 1 D BDF1,GIP2,SCL1,SIP2,AMA1,USA1,ULA1,PRE7,UBR1,RPN11,YMR1,REC114,RPN7,RPD3,RPT1,FYV6,SHR5,CNE1,PRP5,ECM2,SHP1,ADY2,LEO1,GLC3,PUP2,SIZ1,PPH22,PRE10,TAD3,RPT2,MSY1,YAF9,RPN5,LUC7,RPT3,ASI2,SSQ1,RAD59,PAP2,PAI3,DDR48,UBC4,CET1,PBN1,DDI1,SET3,UBX7,CDC46,SLT2,SPO11,PKH2,SKP1,RAD2,RUP1,NTA1,HYS2,PCL6,KNS1,NPL4,ALG2,UBP15,GLC8,FAA1,UFD1,GRR1,BET4,STE11,RPH1,PRB1,SNU71,VID30,RPN9,UBP6,ISW1,CST6,AOS1,GLG2,TPK1,BRO1,SWI1,RAD18,JSN1,PRI1,PPG1,PMT2,MMS4,UFD2,MAG1,RAD50,KRE9,MEC1,GLG1,GPH1,DAP2,PNC1,CDC73,SGA1,MSL5,PAN3,YRF1-2,FMT1,IMP2prime,RIM11,UBC8,NAM2,MSC1,DHH1,PBS2,TRA1,IMP1,SET2,PSK2,MCM3,PPM1,CUS2,DOA1,TPK2,SSK2,EPL1,PHR1,APC9,RAD1,HST3,LSB6,OCT1,ALG13,UBI4,THP1,PTP2,MRK1,RAD6,RPN3,CMK1,SWD2,SIF2,RCK2,RSC9,MSK1,PHO23,DCS1,PRP4,RSE1,EXO1,RAD52,KIN82,PUP1,COX20,PRP12,RAD26,PCL7,RIM20,UBA3,PAP1,RPN6,BMH2,POP5,VPS15,SEC12,MSR1,AHC1,PAF1,MUM2,YPI1,TRM12,UBP2,RIM4,YKU80,BUL1,GSY2,UBX6,KTR4,BMH1,MUS81,MST1,UGP1,PRP22,YPK1,PRE1,MPT5,YKU70,YTA7,SNF5,YPK2,HSM3,SDS24,UBX5,LAP4,RFA1,LTP1,QRI8,GPI19,SKN1,GDB1,TDP1,STE24,XRS2 GO:0006351 7 transcription, DNA-dependent 441 0,0683 47 0,0589 1 D TFG1,MAL13,POG1,RPD3,MED4,LEO1,YRR1,RPB7,SPT2,SNF4,YAF9,CDC46,RPH1,CST6,UGA3,MED8,CCL1,RPO41,PNC1,INO4,CDC73,TRA1,SET2,EPL1,HST3,THP1,SWD2,SIF2,RSC9,ARO80,RTG1,SWI5,MAL33,PAF1,CIN5,PRP45,RSF1,YKU80,YRM1,RPB4,NUT2,MPT5,YKU70,AZF1,PUT3,CSR2,GAL11 GO:0006342 12,7,10,5 chromatin silencing 79 0,0122 8 0,01 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,YKU70 GO:0046483 5 heterocycle metabolism 71 0,011 8 0,01 1 D COX15,HMX1,PHO2,BIO3,TRP4,ADE8,HEM15,ADE2 GO:0006486 9,8 protein amino acid glycosylation 67 0,0104 5 0,0063 1 D ALG2,PMT2,ALG13,KTR4,UGP1 GO:0051231 10 spindle elongation 16 0,0025 1 0,0013 1 D APC9 GO:0009066 7,8 aspartate family amino acid metabolism 45 0,007 4 0,005 1 D ASP3-3,CHA1,ASP3-4,MET22 GO:0008204 7,8,9 ergosterol metabolism 25 0,0039 2 0,0025 1 D MCR1,ERG9 GO:0006633 8,7,6 fatty acid biosynthesis 12 0,0019 1 0,0013 1 D ETR1 GO:0042434 7 indole derivative metabolism 10 0,0015 1 0,0013 1 D TRP4 GO:0015931 5,6 nucleobase, nucleoside, nucleotide and nucleic acid transport 80 0,0124 7 0,0088 1 D NPL3,MEX67,THP1,PAP1,ASM4,RPB4,CRM1 GO:0051453 9,6 regulation of cellular pH 23 0,0036 2 0,0025 1 D SKP1,RAV2 GO:0006493 10,9 protein amino acid O-linked glycosylation 16 0,0025 1 0,0013 1 D PMT2 GO:0000162 10,9,8,11 tryptophan biosynthesis 10 0,0015 1 0,0013 1 D TRP4 GO:0016125 6,7,8 sterol metabolism 37 0,0057 4 0,005 1 D MCR1,ERG9,DAP1,TGL1 GO:0008380 8 RNA splicing 126 0,0195 11 0,0138 1 D USA1,PRP5,ECM2,LUC7,SNU71,MSL5,NAM2,CUS2,PRP4,RSE1,PRP22 GO:0007076 9,8,7 mitotic chromosome condensation 9 0,0014 1 0,0013 1 D PAP2 GO:0016044 5 membrane organization and biogenesis 32 0,005 3 0,0038 1 D TAZ1,CRD1,SAM50 GO:0007067 7 mitosis 146 0,0226 7 0,0088 1 D BUB3,PPH22,PAP2,CCL1,MPS1,APC9,MAD1 GO:0006999 7 nuclear pore organization and biogenesis 27 0,0042 1 0,0013 1 D ASM4 GO:0045934 7 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 138 0,0214 11 0,0138 1 D RPD3,SPT2,YAF9,CDC46,RPH1,CCL1,PNC1,HST3,SIF2,YKU80,YKU70 GO:0009116 6 nucleoside metabolism 14 0,0022 1 0,0013 1 D ISN1 GO:0006865 6,7,8 amino acid transport 37 0,0057 4 0,005 1 D AVT3,MUP3,AGP2,DIP5 GO:0007068 9,1 negative regulation of transcription, mitotic 10 0,0015 1 0,0013 1 D CCL1 GO:0042435 8,6 indole derivative biosynthesis 10 0,0015 1 0,0013 1 D TRP4 GO:0030846 10 transcription termination from Pol II promoter, RNA polymerase(A) coupled 10 0,0015 1 0,0013 1 D SWD2 GO:0031323 5 regulation of cellular metabolism 403 0,0624 48 0,0602 1 D MAL13,POG1,RPD3,FYV10,COX14,YRR1,SPT2,RMD5,SNF4,YAF9,CDC46,PCL6,RPH1,VID30,UGA3,JSN1,GTS1,CCL1,PNC1,INO4,UBC8,DHH1,TRA1,SET2,SLF1,OAF1,EPL1,HST3,ECM32,SIF2,RSC9,ARO80,DCS1,PCL7,EAP1,SWI5,MAL33,CIN5,PRP45,YKU80,YRM1,GID8,MPT5,YKU70,AZF1,PUT3,CSR2,PHB1 GO:0030466 13,8,11,6 chromatin silencing at silent mating-type cassette 22 0,0034 1 0,0013 1 D RPD3 GO:0006694 7,6,8 steroid biosynthesis 36 0,0056 3 0,0038 1 D OSH6,MCR1,ERG9 GO:0030471 4 spindle pole body and microtubule cycle (sensu Fungi) 37 0,0057 2 0,0025 1 D MPS1,CDC37 GO:0031505 7 cell wall organization and biogenesis (sensu Fungi) 21 0,0033 1 0,0013 1 D SKN1 GO:0000767 6,5 cellular morphogenesis during conjugation 18 0,0028 1 0,0013 1 D AFR1 GO:0016071 7 mRNA metabolism 185 0,0287 19 0,0238 1 D USA1,PRP5,ECM2,LUC7,CET1,UFD1,SNU71,JSN1,MSL5,PAN3,DHH1,CUS2,SWD2,DCS1,PRP4,RSE1,PAP1,PRP22,MPT5 GO:0031497 10 chromatin assembly 84 0,013 8 0,01 1 D RPD3,YAF9,CDC46,PNC1,HST3,SIF2,YKU80,YKU70 GO:0006366 8 transcription from RNA polymerase II promoter 277 0,0429 34 0,0426 1 D TFG1,POG1,MED4,LEO1,YRR1,RPB7,SPT2,SNF4,RPH1,CST6,UGA3,MED8,CCL1,INO4,CDC73,TRA1,EPL1,THP1,SWD2,SIF2,RSC9,ARO80,RTG1,SWI5,PAF1,CIN5,PRP45,RSF1,YRM1,RPB4,NUT2,PUT3,CSR2,GAL11 GO:0008033 8 tRNA processing 34 0,0053 1 0,0013 1 D POP5 GO:0006405 10,8,9,7 RNA export from nucleus 72 0,0112 7 0,0088 1 D NPL3,MEX67,THP1,PAP1,ASM4,RPB4,CRM1